/* pink var hiddedn part *

body.resource-library.video-library.ps3-video.lynhcp-pro-integrate #videos,
body.resource-library.video-library.ps3-video.lynhcp-pro-integrate #tab-opener-2 {
    display: none ;
}

/* pink var hiddedn part */

.fullnavigation .navbar-default .navbar-nav>li>a:focus-visible {
    outline: auto;
}
/*staging 1 feedback isuues*/
.indication-inner-tray.container-center > div, .isi-tray-content .inner-trays > div {
    display: none;
}
.indication-inner-tray.container-center > div:first-child, .isi-tray-content .inner-trays > div:nth-child(2) {
    display: block;
}
.prostate-home #home-main-section .three-column-box>.box .box-image {
    max-width: 65px !important;
}

.nccn-guidelines.lynhcp-pro-integrate .sec-two .card-content p.card-body:nth-child(5) em {
    margin-right: 2px;
}

.nccn-guidelines .pink_eyebrow h1.container-center.ff-roboto-bold sup {
    margin-left: 2px;
}

.nccn-guidelines .sec-one p.card-heading.pink-color.ff-roboto-bold.fw-bold em {
    content: "";
    margin-right: 1px;
}

.nccn-guidelines .sec-two p.card-heading.blue-color.ff-roboto-bold.fw-bold em {
    content: "";
    margin-right: 1px;
}

.moa p.sub-heading.spadd {
    padding-bottom: 18px;
    margin: 0px;
}

.moa p.sub-heading.spadd-m {
    margin: 0px;
    padding-bottom: 5px;
    margin-top: -5px;
}

body.monotherapy.profound.efficacy.prostrate_efficacy.profound-efficacy.monotherapy3.lynhcp-pro-integrate .efficacy-mono.section-2 ul.list-section li.list-item .list-bullet {
    margin-left: -15px;
}

body.monotherapy.profound.efficacy.prostrate_efficacy.profound-efficacy.monotherapy3.lynhcp-pro-integrate .efficacy-mono.section-2 ul.list-section li.list-item {
    padding-left: 15px;
}

body.prostrate_efficacy .section-4 .efficacy-graph-container .graph-data p.fw-bold.ff-roboto-bold.last-para span i:after,
body.prostrate_efficacy .section-2 .efficacy-graph-container .graph-data p.fw-bold.ff-roboto-bold span i:after {
    margin-left: 0.8px;
    content: "";
}
body.resource-library.video-library.ps3-video.lynhcp-pro-integrate #videos .desc-body>a {
    pointer-events: none;
}
/* end staging 1 feedback isuues*/
.home .box-2 .box-content p:nth-child(3) {
    padding-bottom: 8px !important;
}

.combination-therapy .section-2 ul.list-section li:nth-child(1) {
    padding-bottom: 4px;
}

body.prostrate_efficacy .lt-green-bg.section-3 {
    padding: 40px 0 20px 0px !important;
}

body.combination-therapy.safety-tolerability.safety-combination-theraphy.pc3-combi.lynhcp-pro-integrate .propel-content .cta-button a:after {
    margin-left: 15px;
}

body.combination-therapy.safety-tolerability.safety-combination-theraphy.pc3-combi.lynhcp-pro-integrate .propel-content .cta-button a {
    padding: 15px 13px;
}

.patient-profiles .mono-patient-profile .pgend-navigator .cta-button a {
    padding: 15px 15px;
}

body.moa.mechanism-of-action .hp-margin,
.moa .hg-margin {
    padding-top: 3px;
    padding-bottom: 3px;
    display: flex;
}

.moa .propel-content .cta-button a:after,
.nccn-guidelines .propel-content .cta-button a:after {
    margin-left: 10px;
}

.moa .propel-content .cta-button a,
.nccn-guidelines .propel-content .cta-button a {
    padding: 15px 15px;
}

body.moa.mechanism-of-action .hp-margin span,
.moa .hg-margin span {
    line-height: 18px;
}

/*safety-monotherapy*/
.safetylistsect ul {
    color: #333333;
}

.treatment-paradigm .pink_eyebrow,
.safety-tolerability .pink_eyebrow,
.hrrm-testing .pink_eyebrow {
    background: #990064 0% 0% no-repeat padding-box;
}

.safety-tolerability .section-one,
.section-two {
    padding-bottom: 0px !important;
}

.monotherapy.safety-tolerability .clinicalstudytxt {
    margin-top: 35px !important;
}

.monotherapy .safetylistsect li span.left3 {
    left: -7px;
    position: relative;
}

.monotherapy .section-one .safetylistsect li {
    margin-top: 5px;
    margin-bottom: 5px;
}

.monotherapy .cta-button a:after {
    margin-left: 15px;
}

/*safety-combination-therapy*/
.mechanism-of-action .moa-combi .end-notes p.footnotes:last-child {
    text-indent: 0px !important;
}

.safety-combination-theraphy .footnotecontiner.container-center {
    padding-left: 10px;
}

span.text-block {
    display: block;
}

.cta-margin {
    margin-top: 40px;
    left: 10px;
    position: relative;
}

.cta-margin .cta-button {
    max-width: none !important;
}

.safety-tolerability .section-one .pink_eyebrow h1 span {
    margin-left: -2px;
}

.safety-combination-theraphy .safetylistsect li span.left3 {
    left: -7px;
    position: relative;
}

.safety-combination-theraphy #footer .footnote {
    margin-bottom: 10px;
}

/*about lynparza Hypothetical Patient Cases-Combination therapy*/
.patient-profiles .combi-patient-profile .skew-maroon-head {
    box-shadow: none;
}

.patient-profiles .pgend-navigator .cta-button a:after,
.moa .propel-content .cta-button a:after {
    margin-left: 15px;
}

/*about lynparza Hypothetical Patient Cases-monotherapy*/

.patient-profiles .end-banner-patient .william-opt,
.patient-profiles .end-banner-patient .joe-opt {
    background-color: #990064;
}

.patient-profiles .end-banner-patient .col-xs-12.col-sm-6.joe-pot .joe-opt,
.patient-profiles .end-banner-patient .col-xs-12.col-sm-6.william-pot .william-opt {
    max-width: 485px;
    transform: skewX(170deg);
    width: 96%;
}

.patient-profiles .end-banner-patient .col-xs-12.col-sm-6.william-pot .william-opt {
    margin-left: 5%;
}

.patient-profiles .end-banner-patient p {
    font-size: 18px;
    line-height: 23px;
    padding: 24px 10px;
}

.patient-profiles .end-banner-patient {
    margin-top: 40px;
}

.patient-profiles .pat-detail h4 {
    color: #990064;
}

.patient-profiles p.fact-head {
    color: #990064;
}

.clear-both {
    clear: both
}

.pad-top10 {
    padding-top: 1px;
}

.patient-profiles ::marker {
    font-size: 15px;
    line-height: 20px;
    vertical-align: middle;
    color: #59595B;
}

/*about-lynparza-moa*/
.moa.mechanism-of-action .pink_eyebrow {
    padding-top: 67px;
    padding-bottom: 50px;
    background: #990064 0% 0% no-repeat padding-box;
    color: #ffffff;
}

.hp-margin {
    margin-bottom: 16px;
    clip-path: polygon(0 0, 100% 0%, 96% 100%, 0% 100%);
    background: #990064;
    width: fit-content;
    padding: 3px 15px 3px 10px;
}

.hg-margin {
    margin-bottom: 16px;
    clip-path: polygon(0 0, 100% 0%, 96% 100%, 0% 100%);
    background: #004D74;
    width: fit-content;
    padding: 3px 15px 3px 10px;
}

span.hc-text-bg {
    font-size: 16px;
    font-family: "futura-pt-bold", sans-serif;
    color: #ffffff;
    letter-spacing: 1.6px;
    font-weight: bold;
}

.moa.mechanism-of-action .pink_eyebrow h1.container-center {
    padding: 0px;
    font-size: 30px;
    line-height: 36px;
}

.moa.mechanism-of-action img.img-responsive.desktop.img-responsive-desktop1 {
    width: 100%;
}

.moa-combi .sect-1 .heading-1 {
    margin-top: 20px;
}

p.footnote.note-text {
    font-size: 10px !important;
    line-height: 12px !important;
    font-family: 'MyriadPro-Bold';
    margin-bottom: 16px;
}

p.footnote.subnote-text {
    font-size: 10px !important;
    line-height: 11px !important;
    font-family: 'MyriadPro-Regular';
}

.moa p.footnote.subnote-text {
    font-size: 12px !important;
    line-height: 14px !important;
}

/*about-lynparza-nccn*/
.nccn-guidelines.lynhcp-pro-integrate .pink_eyebrow {
    padding-top: 40px;
    padding-bottom: 40px;
    background: #990064 0% 0% no-repeat padding-box;
    color: #ffffff;
}

.nccn-guidelines.lynhcp-pro-integrate .pink_eyebrow h1.container-center {
    padding: 0px;
    font-size: 30px;
    line-height: 36px;
}

.nccn-guidelines.lynhcp-pro-integrate .nccn-mono.container-center {
    display: block !important;
}

.nccn-guidelines.lynhcp-pro-integrate .heading-1 {
    margin-top: 40px;
}


body.nccn-guidelines .mono-foots .footnotecontiner.container-center, 
body.nccn-guidelines .mono-foots .reference.container-center {
    padding-right: 20px;
    padding-left: 10px;
}

.nccn-guidelines.lynhcp-pro-integrate .therapy.flex-container.max-width {
    display: flex;
    gap: 16px;
    margin: 20px 0px 16px;
    max-width: 1004px;
}

.nccn-guidelines.lynhcp-pro-integrate p.font-h {
    font-size: 20px;
    line-height: 26px;
}

.nccn-guidelines.lynhcp-pro-integrate .card.combination {
    padding: 0px 0 10px;
    background: #E5EDF0;
    overflow: hidden;
}

.nccn-guidelines.lynhcp-pro-integrate .label-heading {
    width: fit-content;
    margin-left: -3px;
}

.nccn-guidelines.lynhcp-pro-integrate .label-heading p {
    /*padding: 7px 22px 7px 22px;*/
    /*padding: 7px 12px 7px 9px;*/
    padding: 0px 15px 0px 12px;
    letter-spacing: 1.98px;
    font-size: 16px;
}

.nccn-guidelines.lynhcp-pro-integrate .card-content {
    text-align: left;
    margin-top: 0px;
    padding: 0 30px;
}

.nccn-guidelines.lynhcp-pro-integrate .card-content p.card-heading {
    /*font-size: 20px;*/
    font-size: 18px;
    letter-spacing: 0.27px;
    line-height: 24px;
}

.nccn-guidelines.lynhcp-pro-integrate .card-content .card-body {
    color: #57585B;
    font-size: 16px;
    line-height: 20px;
    margin-bottom: 16px;
}

.nccn-guidelines.lynhcp-pro-integrate hr {
    border-top: 1px solid #707070;
    margin: 16px 0px;
}

.nccn-guidelines.lynhcp-pro-integrate .card.monotherapy {
    padding: 0px 0 10px;
    background: #E5EDF0;
    overflow: hidden;
}

.nccn-guidelines.lynhcp-pro-integrate .footnotes.tabs_desktop.tabs_desktop-left p {
    margin-left: 0px;
}

.nccn-guidelines.lynhcp-pro-integrate p.indent {
    font-size: 10px;
    line-height: 12px;
    color: #525252;
    font-family: 'MyriadPro-Regular';
}

.nccn-guidelines.lynhcp-pro-integrate p.indent.para1 {
    font-weight: bold;
    font-family: 'MyriadPro-Bold';
}

.nccn-guidelines.lynhcp-pro-integrate .mono-foots,
.mechanism-of-action .moa-mono {
    display: block;
}

.nccn-guidelines.lynhcp-pro-integrate .tabs_desktop {
    display: block;
}

.nccn-guidelines.lynhcp-pro-integrate .heading-1 h2 {
    font-size: 25px;
    line-height: 28px;
    font-family: 'Roboto-Bold', sans-serif !important;
}

/*resources page */

body.resource-library.video-library.ps3-video.lynhcp-pro-integrate .video-frame.video-frames-new,body.resource-library.video-library.ps3-video.lynhcp-pro-integrate .grid .thumbnail .thumb {
    background: #888888;
    opacity: 1;
    pointer-events: none;
}

body.resource-library.video-library.ps3-video.lynhcp-pro-integrate .video-frame.video-frames-new>a>img,body.resource-library.video-library.ps3-video.lynhcp-pro-integrate .grid .thumbnail .thumb>img {
    visibility: hidden;
}
body.resource-library.video-library.ps3-video.lynhcp-pro-integrate .grid .thumbnail .thumb>img+.play {
    display: none;
}

.resource-library.video-library.ps3-video.lynhcp-pro-integrate .pancreatic-column,
.pancreatic-column-1 {
    border: 1px solid #707070;
    background: #fff;
    margin-top: 0px;
}

.resource-library #resources .down-res {
    margin-bottom: 40px;
}

.resource-library.video-library.ps3-video.lynhcp-pro-integrate .pan-col-text,
.pan-col-text.patient-text {
    color: #000000;
    padding-top: 0px;
}

.resource-library.video-library.ps3-video.lynhcp-pro-integrate .blue-color {
    text-decoration: underline;
    font-weight: bold;
    font-size: 18px;
    line-height: 24px;
    font-family: 'Roboto-Bold', sans-serif !important;
}

.resource-library.video-library.ps3-video.lynhcp-pro-integrate .blue-color:hover {
    text-decoration: none;
}

.resource-library.video-library.ps3-video.lynhcp-pro-integrate img.d-ima {
    margin-left: 10px;
}

/*new code*/
.resource-library.video-library.ps3-video.lynhcp-pro-integrate .pancreatic-column,
.pancreatic-column-1 {
    height: auto;
}

.resource-library.video-library.ps3-video.lynhcp-pro-integrate .box.box-1.flex-container {
    display: flex;
}

.resource-library.video-library.ps3-video.lynhcp-pro-integrate .box-content {
    padding-left: 15px;
}

.resource-library.video-library.ps3-video.lynhcp-pro-integrate .box-image img {
    max-width: 150px;
    height: 113px;
    object-fit: contain;
}

.resource-library.video-library.ps3-video.lynhcp-pro-integrate .pancreatic-column,
.pancreatic-column-1 {
    padding: 15px 15px;
}

.resource-library.video-library.ps3-video.lynhcp-pro-integrate .pancreatic-column {
    margin-bottom: -10px;
}

.resource-library.video-library.ps3-video.lynhcp-pro-integrate .box-content {
    padding-left: 15px;
    padding-right: 15px;
}

.pancreatic-column,
.pancreatic-column-1 {
    background-color: #fff !important;
    padding: 15px 18px !important;
}

p.box-body.pan-col-text.pad-right-20 {
    padding-right: 40px;
}

.pan-col-head p {
    font-size: 18px !important;
}

/*resources page hcp videos */
.ps3-video .desc p.desc-head {
    font-size: 20px;
    line-height: 24px;
}

.ps3-video .desc-body,
.ps3-video .desc .boldText {
    font-size: 16px;
    color: #333333;
}

.ps3-video .thumbnail .thumb-head p {
    font-size: 20px;
    line-height: 24px;
    color: #333333;
}

.lynhcp-pro-integrate.video-library #videos>div.grid:first-child>div .col-xs-12.col-sm-8 {
    max-width: 579px;
}

.lynhcp-pro-integrate.video-library #videos>div.grid:first-child>div .col-xs-12.col-sm-4 {
    background-color: #f3f7f8;
}

.lynhcp-pro-integrate.video-library #videos>div.grid:first-child>div .col-xs-12.col-sm-4>div .desc {
    margin: 0 auto !important;
}

.patient-profiles.lynhcp-pro-integrate .med-facts ul li {
    list-style-type: none;
}
p.image-after em:after {
    display:none;
    
}

.isi-body .info-report>p:last-child:after {
     content: url('/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-global/bluelinkout.svg');
     width: 13px !important;
     display: inline-block;
     right: unset !important;
     margin-left: 2px;
}
.isi-body .info-report>p:last-child:after {
    display: none;
}
.isi-body .info-report>p a.icon-after-dot:after {
    content: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-global/bluelinkout.svg);
    width: 13px !important;
    display: inline-block;
    right: unset !important;
    position: absolute;
    margin-left: 6px;
    margin-top: 1px;
}
.isi-body .info-report>p a.icon-before-dot i:after {
    content: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-global/bluelinkout.svg);
    width: 13px !important;
    display: inline-block;
    right: unset !important;
    position: absolute;
    margin-left: 3px;
    margin-top: 1px;
}
.isi-body .info-report>p a.icon-before-dot i {
    padding-right: 17px;
}
.isi-body .info-report>p:last-child>a {
    padding: 0 !important;
}
.ps3-video #maincontent .desc h2.desc-head {
    font-size: 20px;
    line-height: 24px;
    font-family: "Roboto-Bold";
    color: #004D74;
    margin: 0 0 10px;
}
.ps3-video #maincontent .thumbnail .thumb-head h2 {
    font-size: 20px;
    line-height: 24px;
    color: #333333;
    font-family: "Roboto-Bold";
    margin: 0 0 10px;
}

/* live-issues fix starts */

.pr-tumor-type .reference-container a, .pr-tumor-type .reference a {
  color: black;
  pointer-events: none;
}


/* live-issues fix ends*/

@media screen and (min-width: 1031px) and (max-width: 1362px) {

    .patient-profiles .end-banner-patient .col-xs-12.col-sm-6.joe-pot .joe-opt,
    .patient-profiles .end-banner-patient .col-xs-12.col-sm-6.william-pot .william-opt {

        width: 90%;
    }

    .patient-profiles .end-banner-patient .col-xs-12.col-sm-6.william-pot .william-opt {
        margin-left: 0%;
    }
}

@media screen and (min-width: 993px) and (max-width: 1031px) {

    .patient-profiles .end-banner-patient .col-xs-12.col-sm-6.joe-pot .joe-opt,
    .patient-profiles .end-banner-patient .col-xs-12.col-sm-6.william-pot .william-opt {

        width: 100%;
    }

    .patient-profiles .end-banner-patient .col-xs-12.col-sm-6.william-pot .william-opt {
        margin-left: 0%;
    }
}
@media screen and (min-width:1004px) and (max-width:1100px) {
    body.profound.safety-tolerability .pink_eyebrow, .monotherapy.safety-tolerability .clinicalstudytxt,body.monotherapy.profound.safety-tolerability.lynhcp-pro-integrate .section-one .footnotecontiner, body.monotherapy.profound.safety-tolerability.lynhcp-pro-integrate .section-one .footnotecontiner+.safetylistsect,.safety-combination-theraphy .pink_eyebrow, .neww-table.safety-olympia-table.sp1-table1, .safety-combination-theraphy .footnotecontiner.container-center, .safety-tolerability .section-two,.safety-combination-theraphy .footnotecontiner.container-center+.container-center.safetylistsect {
        padding-left: 30px !important;
        padding-right: 30px;
    }
    
    .safety-combination-theraphy .pink_eyebrow + .container-center.clinicalstudytxt {
        padding-left: 30px;
    }
	.patient-profiles .combi-patient-profile>.container-center,.patient-profiles .mono-patient-profile>.container-center {
	    padding-left: 30px;
	    padding-right: 30px;
	}

	.patient-profiles .tab-head-container {
	    max-width: 90%;
	}
	.moa.mechanism-of-action .pink_eyebrow,.moa.mechanism-of-action .maincontent.parsys>.rich-text.text.parbase.section+.rich-text.text.parbase.section {
	    padding-left: 30px;
	    padding-right: 30px;
	}
    .nccn-guidelines.lynhcp-pro-integrate .pink_eyebrow,.nccn-guidelines.lynhcp-pro-integrate .maincontent>.rich-text.text.parbase.section+.rich-text.text.parbase.section {
	    padding-left: 30px;
	    padding-right: 30px;
	}
    body.resource-library.video-library.ps3-video.lynhcp-pro-integrate .maincontent {
	    padding: 0 30px;
	}
	.resource-library.video-library.ps3-video.lynhcp-pro-integrate .double-pan-column {
	    width: 40% !important;
	}

	.resource-library.video-library.ps3-video.lynhcp-pro-integrate .double-pan-column:nth-child(2) .pancreatic-column.patient-column {
	    margin-left: 120px;
	}
    .resource-library.video-library.ps3-video.lynhcp-pro-integrate div#videos.tab-pane.active.in>.grid.section>.clearfix {
	    display: flex;
	    align-items: center;
	    justify-content: space-between;
	}

	.resource-library.video-library.ps3-video.lynhcp-pro-integrate div#videos.tab-pane.active.in>.grid.section>.clearfix>.col-xs-12 {
	    flex: 1 1 auto;
	}
}

@media screen and (min-width:1004px) and (max-width:1024px){
    .fullnavigation .navbar-default .navbar-nav {
        margin: 0;
        padding-right: 50px;
    }
}

@media screen and (min-width: 1004px) {

    body.patient-profiles .combi-patient-profile .patient-profile-wrap li:before, body.patient-profiles .med-facts ul li:before {
        top: 0 !important;
    }
    body.patient-profiles .combi-patient-profile .patient-profile-wrap li:before {
    	top: 1px !important;
	}
    body.resource-library.video-library.ps3-video.lynhcp-pro-integrate div#videos>.grid>.clearfix {
 	   padding-right: 0;
	}


    /*staging 1 feedback isuues*/
    body.prostrate_efficacy .maincontent .heading p {
        margin-left: -10px;
    }

    .dosing .container-center.footnote_end.paddingLeft10.m-paddingLef20.margintop0 {
        padding-left: 0px;
        /*padding-right: 0px;*/
    }

    .dosing .refs.reference {
        padding-left: 0px;
        /*padding-right: 0px;*/
    }

    .dosing .refs.reference .container-center.inner-wrapper {
        padding-left: 0px;
        /*padding-right: 0px;*/
    }

    .nccn-guidelines.lynhcp-pro-integrate .label-heading p {
        letter-spacing: 1.98px;
        padding: 4px 12px 4px;
        font-size: 16px;
        line-height: 16px;
        font-weight: 700;
        font-family: 'futura-pt';
        font-style: oblique;
    }

    /*staging 1 feedback isuues*/

    /* reopen issues starts */
    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .double-pan-column:nth-child(2) {
        padding-left: 5px;
    }

    body.monotherapy.profound.safety-tolerability.lynhcp-pro-integrate .section-one .footnotecontiner {
        padding-left: 20px;
    }

    body.monotherapy.profound.safety-tolerability.lynhcp-pro-integrate .section-two .footnotecontiner {
        padding-left: 16px;
    }

    body.monotherapy.profound.safety-tolerability.lynhcp-pro-integrate .section-one .footnotecontiner+.safetylistsect {
        max-width: 1004px;
        padding: 0 0 0 6px;
    }

    .patient-profiles .combi-patient-profile .patient-profile-wrap {
        padding-left: 12%;
    }

    .patient-profiles .joe .pat-detail img.desktop {
        max-width: 324px !important;
    }

    /* reopen issues ends */
    .safety-combination-theraphy .footnotecontiner.container-center {
        padding-left: 15px;
    }

    .safety-combination-theraphy .pink_eyebrow {
        padding: 51px 0 39px;
    }

    .patient-profiles .combi-patient-profile .med-facts p {
        padding: 0 10px 0 50px;
    }

    .patient-profiles .med-facts p {
        text-indent: -14px !important;
    }

    .patient-profiles .mono-patient-profile .joe-history .med-facts p,
    .patient-profiles .william-history .med-facts p {
        padding-left: 47px;
    }

    body.prostrate_efficacy .efficacy-graph-container .graph-head:nth-child(1) {
        padding-top: 30px !important;
    }

    .monotherapy.safetylistsect li,
    .combination-therapy .safetylistsect li {
        margin-top: 2px;
        margin-bottom: 2px;
    }

    .monotherapy .section-one .safetylistsect li {
        margin-top: 0px;
        margin-bottom: 0px;
    }

    .testing .section-4 .table .flex-container.flex-3 .box-3 {
        padding-right: 19px;
    }

    .testing .section-4 .table .flex-container.flex-3 .box-3 ul li.list-item:nth-child(3) span.text-nowrap {
        text-wrap: wrap;
    }

    .dose-modification table tr td {
        font-size: 16px;
        line-height: 20px;
    }

    .dosing .section-2 .abiraterone.blue-bg .daily-double p {
        font-size: 20px !important;
        line-height: 28px !important;
    }

    .monotherapy .section-9 {
        margin-bottom: -10px !important;
    }

    .pad20 {
        padding-right: 21px;
    }

    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .patient-res .pancreatic-column {
        margin-bottom: 10px;
    }

    .video-frame img {
        /* width: 640px; */
        max-width: 579px !important;
        width: 100%;
        max-height: 326px !important;
        height: 100%;
    }

    .grid.section:nth-child(2) {
        padding-top: 59px;
    }

    .desc-wrapper .desc {
        padding: 85px 0px 10px 12px !important;
        margin-left: -74px !important;
    }

    .resource-library .hcp-res.resources-padding-lt {
        padding-top: 1px !important;
    }

    .moa .cta-margin {
        margin-top: 55px;
    }

    .moa .moa-combi.container-center {
        padding-right: 0px;
        padding-left: 0px;
    }

    .patient-profiles .reference,
    .moa .reference {
        padding-right: 10px;
    }

    .patient-profiles .med-facts ul li:before {
        margin-left: -6px;
        content: "•";
        font-size: 18px;
        position: relative;
        left: -5px;
        top: 2px;
    }

    .patient-profiles .med-facts p:before {
        content: "";
        margin-left: -5px;
    }

    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .patient-res a.blue-color {
        font-size: 18px;
    }

    .resource-library.video-library.ps3-video.lynhcp-pro-integrate #patient-resources .down-res {
        padding-bottom: 30px;
    }

    .padd-top10 {
        padding-top: 10px;
    }

    .patient-profiles .combi-patient-profile .patient-profile-wrap h4 {
        font-size: 25px;
        line-height: 26px;
    }

    .fullnavigation li.about-lynparza ul.dropdown-menu.multi-level li:nth-child(2),
    .fullnavigation li.resource-library ul.dropdown-menu.multi-level li:nth-child(2) {
        margin-bottom: -10px;
    }

    .monotherapy .section-6 h2.skew10.white-color.ff-roboto-bold {
        padding-right: 58px;
    }

    /*proofing issues*/
    .monotherapy .section-4 .efficacy-mono ul.list-section li.list-item .list-bullet {
        margin-left: -11px;
        margin-right: 4px;
    }

    .monotherapy .section-one .container-center.safetylistsect {
        padding-right: 0px !important;
    }

    .patient-profiles.lynhcp-pro-integrate .maincontent.parsys .mono-patient-profile .container-center.treatment-path-container .trate-path-head,
    .patient-profiles.lynhcp-pro-integrate .maincontent.parsys .combi-patient-profile .container-center .trate-path-head {
        margin-left: -10px;
    }

    .patient-profiles .combi-patient-profile .med-facts li>span:nth-child(1) {
        left: -4px;
        position: relative;
    }

    .patient-profiles .combi-patient-profile .profile-cont li span:nth-child(1) {
        left: -4px;
        position: relative;
    }

    .patient-profiles.lynhcp-pro-integrate .mono-patient-profile .joe-history,
    .patient-profiles.lynhcp-pro-integrate .mono-patient-profile .william-history {
        height: 480px;
    }

    .patient-profiles.lynhcp-pro-integrate .mono-patient-profile .joe-history,
    .patient-profiles.lynhcp-pro-integrate .mono-patient-profile .william-history {
        height: 505px;
    }

    .margin-left12 {
        margin-right: 12px !important;
    }

    /*end proofing issues*/
    .lynhcp-pro-integrate.video-library #videos>div.grid:first-child>div .col-xs-12.col-sm-8 {
        max-width: 579px;
    }

    .lynhcp-pro-integrate.video-library #videos>div.grid:first-child>div .col-xs-12.col-sm-4 {
        width: 40%;
    }

    .lynhcp-pro-integrate.video-library #videos>div.grid:first-child>div .col-xs-12.col-sm-4>div .desc {
        padding: 73px 0 75px 16px !important;
    }
}

@media screen and (max-width: 1003px) {
    .isi-body .info-report>p:last-child:after {margin-top: 1px;}
    .isi-body .info-report>p a.icon-after-dot:after {
    	margin-top: 3px;
	}
    .patient-profiles .combi-patient-profile .skew-maroon-head h2 {
	    font-size: 16px;
	    line-height: 20px;
	}
	.resource-library.video-library.ps3-video.lynhcp-pro-integrate .double-pan-column {
	    width: 100% !important;
	}
    .patient-profiles .combi-patient-profile .patient-profile-wrap+div {
	    text-align: center !important;
	}
    .moa.mechanism-of-action .pink_eyebrow {
	    padding: 21px 0 !important;
	}
    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .double-pan-column .pancreatic-column.patient-column {
	    width: 100% !important;
	}
	.ps3-video #maincontent .desc h2.desc-head {
	    margin-top: 10px;
	}
	.ps3-video #maincontent .thumbnail .thumb-head h2 {
		font-size: 16px;
	    line-height: 20px;
	}
	.patient-profiles #tab-opener-1 > a {
	    padding: 8px 20px !important;
	}
	.nccn-guidelines.lynhcp-pro-integrate .nccn-mono.container-center {
	    padding-left: 0 !important;
	    padding-right: 0 !important;
	}
	body.safety-tolerability .table-legend ul {
	    margin-right: 7px;
	}
    body.patient-profiles.lynhcp-pro-integrate {} .patient-profiles #tab-opener-1 > a, .patient-profiles #tab-opener-2 > a {
	    line-height: 17px;
	}

	body.patient-profiles.lynhcp-pro-integrate {} .patient-profiles #tab-opener-1 > a {
	    padding: 8px 20px !important;
	}

	body.patient-profiles.lynhcp-pro-integrate {} .patient-profiles #tab-opener-2 > a {
	    padding: 16px 22px;
	}

    /* reopened-issues starts*/
    body.resource-library.video-library.ps3-video.lynhcp-pro-integrate main#maincontent {
        margin-bottom: -30px;
    }

    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .pancreatic-column,
    .pancreatic-column-1:nth-child(3) {
        padding-left: 20px !important;
        padding-right: 0px !important;
    }

    .lynhcp-pro-integrate.nccn-guidelines .monotherapy .label-heading {
        margin-top: 7px;
    }

    body.resource-library.video-library.ps3-video.lynhcp-pro-integrate .patient-res.resources-padding-lt {
        background-color: white;
    }

    body.resource-library.video-library.ps3-video.lynhcp-pro-integrate .patient-res.resources-padding-lt h2>p.down-res {
        font-size: 25px;
        line-height: 28px !important;
    }

    .medical-hist.mobile.col-xs-12.col-sm-6 .joe-history .med-facts p {
        padding-bottom: 5px;
    }

    .patient-profiles #maincontent .patient-profile-wrap .medical-hist.mobile .container-center {
        padding-left: 0 !important;
        padding-right: 0 !important;
    }

    .patient-profiles .mono-patient-profile .joe-history>div:last-child {
        margin-bottom: -7px;
    }

    .patient-profiles .william-opt,
    .patient-profiles .joe-opt {
        background-color: #990064;
    }

    .patient-profiles .william-history .med-facts {
        padding-bottom: 0;
    }

    .patient-profiles .william-history {
        margin-bottom: 15px;
    }

    body.monotherapy.profound.safety-tolerability.lynhcp-pro-integrate .section-one .footnotecontiner {
        padding-left: 15px;
    }

    body.monotherapy.profound.safety-tolerability.lynhcp-pro-integrate .section-one .footnotecontiner>p {
        margin-bottom: 0 !important;
    }

    body.monotherapy.profound.safety-tolerability.lynhcp-pro-integrate .section-one .footnotecontiner+.safetylistsect {
        padding: 0 15px 0 17px;
    }

    body.monotherapy.profound.safety-tolerability.lynhcp-pro-integrate .section-two .footnotecontiner {
        padding-left: 16px;
    }

    body.monotherapy.profound.safety-tolerability.lynhcp-pro-integrate .cta-margin .cta-button a {
        padding: 17px;
    }

    /* reopened-issues ends*/
    .combination-therapy .section-one .safetylistsect {
        /* padding-left: 15px; */
    }

    .patient-profiles .med-facts p {
        text-indent: -14px !important;
    }

    .monotherapy .section-two p.footnote.monotherapy-footnote.mar-top {
        margin-top: 20px !important;
        margin-bottom: 10px !important;
    }

    .combination-therapy .section-one .safetylistsect {
        margin-top: 15px !important;
        margin-bottom: 44px;
    }

    .combination-therapy .section-one .safetylistsect li:nth-child(3) {
        margin-top: 8px;
    }

    .monotherapy .section-one .safetylistsect li:nth-child(3) {
        margin-top: 21px;
        margin-bottom: 55px;
    }

    .monotherapy .section-one .safetylistsect li,
    .combination-therapy .section-one .safetylistsect li {
        margin-top: 5px;
        margin-bottom: 5px;
    }

    .testing .section-4 .table .flex-container .box-3 ul li.list-item:nth-child(3) {
        padding-right: 2px;
    }

    .testing .section-4 .table .flex-container .box-3 ul li.list-item:nth-child(4) {
        padding-right: 3px;
    }

    .testing .section-4 .table .flex-container .box-3 ul li.list-item:nth-child(3) span.text-nowrap {
        text-wrap: wrap;
    }

    .dosing .section-2 .abiraterone.blue-bg .daily-double p {
        font-size: 20px !important;
        line-height: 28px !important;
    }

    .section-5 p span.ff-roboto-bold.last-para.mobile-view-only {
        display: inline-block;
    }

    body.prostrate_efficacy .graph-side-heading {
        margin-top: 35px !important;
    }

    body.prostrate_efficacy .section-2 .propel-content .Primary_endpoint>.prim-endp {
        padding-top: 0px !important;
        margin-top: 0px !important;
    }

    body.prostrate_efficacy .lt-green-bg.section-3 {
        padding-bottom: 0px !important;
    }

    .section-4 .skew-maroon-head.sec71bg.sec71bg1 {
        margin-top: 4px !important;
    }

    .patient-profiles .combi-patient-profile .med-facts li>span:nth-child(1) {
        left: -5px;
        position: relative;
    }

    .nccn-guidelines.lynhcp-pro-integrate .sec-two .card-content .card-body {
        letter-spacing: -0.6px;
    }

    .grid.section {
        background: #f3f7f8;
    }

    .ps3-video .thumbnail .thumb-head p {
        font-size: 16px;
        line-height: 20px;
    }

    .resource-library.video-library.ps3-video p.desc-body.desc-body-george {
        padding-top: 5px;
    }

    .ps3-video .desc-body,
    .ps3-video .desc .boldText {
        padding-top: 10px;
    }

    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .hcp-res .down-res {
        margin-bottom: 5px !important;
        font-size: 25px;
        line-height: 28px !important;
    }

    #videos .patient-res,
    .hcp-res {
        background: unset !important;
    }

    #resources .hcp-res.resources-padding-lt {
        padding-left: 15px !important;
        padding-top: 20px !important;
        background: unset;
    }

    .nccn-guidelines.lynhcp-pro-integrate .heading-1 {
        margin-top: 26px;
    }

    .nccn-guidelines.lynhcp-pro-integrate p.font-h {
        margin-bottom: 18px;
    }

    .nccn-guidelines.lynhcp-pro-integrate .pink_eyebrow h1.container-center {
        padding-right: 20px;
        padding-left: 20px;
    }

    .moa .moa-combi .sect-1,
    .nccn-guidelines .nccn-mono .sect-1 {
        padding: 0px 20px;
    }

    .moa-combi.container-center {
        padding: 0px 0px;
        padding-left: 0px !important;
    }

    .moa.mechanism-of-action .pink_eyebrow h1.container-center {
        padding: 0px 0px 0px 10px;
    }

    .patient-profiles .mono-patient-profile .mobile.joe-history .med-facts li:before,
    .patient-profiles .mono-patient-profile .mobile.william-history .med-facts li:before {
        margin-left: -6px;
        content: "•";
        font-size: 18px;
        position: relative;
        left: -5px;
        top: 2px;
    }

    .patient-profiles .mono-patient-profile .mobile.joe-history .med-facts p,
    .patient-profiles .mobile.william-history .med-facts p {
        padding-left: 25px;
    }

    .patient-profiles .combi-patient-profile .patient-profile-wrap+div {
        overflow: hidden;
        margin: 41px 15px 0 13px;
    }

    .patient-profiles .combi-patient-profile .patient-profile-wrap+div .skew-maroon-head {
        margin-left: 20px;
        padding-left: 20px;
        margin-top: 0;
    }

    /* QA issue */
    body.prostrate_efficacy .propel-examined {
        margin-top: 0px !important;
    }

    body.prostrate_efficacy .efficacy-graph-container .graph-data {
        padding-bottom: 20px !important;
    }

    .padding12 {
        padding-top: 12px;
        padding-bottom: 12px;
    }

    body.dosing-management #maincontent .abiraterone p:nth-child(4) {
        margin: 24px 0 16px;
        padding: 0;
    }

    /* end QA issue */
    /*proofing issues*/
    .nccn-guidelines.lynhcp-pro-integrate .card-content .card-body {
        font-family: 'Roboto-Regular';
    }

    .nccn-guidelines.lynhcp-pro-integrate .card.monotherapy .card-heading {
        line-height: 20px;
    }

    .patient-profiles .pgend-navigator .cta-button a {
        padding: 17px 16px !important
    }

    .patient-profiles .tab-opener-11>a {
        padding: 0px 8px 0px !important;
    }

    .patient-profiles .combi-patient-profile .profile-cont li span:nth-child(1) {
        left: -6px;
        position: relative;
    }

    .safety-combination-theraphy #footer .footnote {
        margin-bottom: 20px !important;
    }

    .monotherapy .safetylistsect li span.left3 {
        left: -6px;
        position: relative;
    }

    .safety-combination-theraphy .safetylistsect li span.left3 {
        left: -3px;
        position: relative;
    }

    body.prostrate_efficacy .propel-content .Primary_endpoint {
        margin-top: 4px !important;
    }

    body.prostrate_efficacy .section-3 .propel-content .heading p {
        padding-top: 10px;
    }

    body.prostrate_efficacy .section-4 .section-heading p {
        margin-top: 20px !important;
    }

    body.prostrate_efficacy .section-3 .efficacy-graph-container .graph-head {
        padding-top: 17px !important;
    }

    body.prostrate_efficacy .section-one-link .propel-examined>p {
        line-height: 28px;
    }

    body.prostrate_efficacy .section-2 .efficacy-graph-container .graph-data {
        padding-top: 10px;
    }

    body.prostrate_efficacy .section-2 .efficacy-graph-container .graph-data ul {
        margin-bottom: 10px;
    }

    body.prostrate_efficacy .section-4 .efficacy-graph-container .graph-data ul {
        margin-bottom: 10px;
    }

    .prostrate_efficacy .section-4 .graph-data p:nth-child(3) {
        padding: 8px 0px;
    }

    .prostrate_efficacy .section-4 .graph-data p:nth-child(6) {
        margin-top: 10px !important;
    }

    body.prostrate_efficacy .section-5 .efficacy-graph-container .graph-data {
        padding-top: 10px !important;
    }

    .efficacy-mono.section-7 .cohort-a {
        margin-top: 0px !important;
    }

    /*end proofing issue*/

    .cta-margin {
        left: 0px;
    }

    .cta-margin .cta-button a {
        padding: 17px 19px;
    }

    .cta-margin .cta-button a:after {
        margin-left: 5px;
    }

    .safety-tolerability .footnote {
        color: #333333 !important;
    }

    span.text-block {
        display: inline-block;
    }

    .medical-hist.mobile.col-xs-12.col-sm-6 .joe-history .med-facts ul li {
        font-size: 20px;
        line-height: 24px;
    }

    .medical-hist.mobile.col-xs-12.col-sm-6 .joe-history .med-facts p {
        font-size: 20px;
        line-height: 24px;
    }

    .mobile.col-xs-12.col-sm-6.william-pot .william-opt {
        width: 85%;
        margin: 40px auto;
    }

    .moa.mechanism-of-action p.footnote.note-text,
    p.footnote.subnote-text {
        font-size: 12px !important;
        line-height: 16px !important;
    }

    .nccn-guidelines.lynhcp-pro-integrate .heading-1 h2 {
        font-size: 25px;
        line-height: 28px;
    }

    .nccn-guidelines.lynhcp-pro-integrate .therapy.flex-container.max-width {
        flex-direction: column;
    }

    .moa.mechanism-of-action .pink_eyebrow h1.container-center,
    .nccn-guidelines.lynhcp-pro-integrate .pink_eyebrow h1.container-center,
    .pink_eyebrow h1.container-center {
        line-height: 30px !important;
        font-size: 24px !important;
        margin-top: 0px;
        padding-left: 0px;
        padding-right: 0px;
        font-family: 'Roboto-Bold', sans-serif !important;
    }

    .nccn-guidelines.lynhcp-pro-integrate .card-content p.card-heading {
        font-size: 18px;
        line-height: 24px;
        margin-bottom: 4px;
    }

    /*resources pages */
    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .pancreatic-column,
    .pancreatic-column-1 {
        margin-left: unset;
        margin-right: unset;
        padding: 10px 10px;
    }

    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .box-content {
        padding-left: 16px;
        margin-right: 25px;
    }

    p.box-body.pan-col-text.pad-right-20 {
        padding-right: unset;
    }

    .pancreatic-column,
    .pancreatic-column-1 {
        padding: 15px 10px !important;
    }

    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .box-content {
        padding-right: unset;
    }

    .patient-res .pancreatic-column,
    .patient-res .pancreatic-column-1 {

        height: auto !important;
    }

    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .down-res {
        padding-right: unset;
        background: #ffffff;
    }

    .patient-res .pancreatic-column,
    .patient-res .pancreatic-column-1 {
        height: auto !important;
    }

    .resource-library.video-library.ps3-video .patient-res .pan-col-head p {
        font-size: 18px;
    }

    .black-top-border-mobile {
        border-top: 2px solid #000 !important;
    }

    .monotherapy.safety-tolerability.lynhcp-pro-integrate .pink_eyebrow {
        padding: 20px;
    }

    .patient-profiles .william-opt p,
    .patient-profiles .joe-opt p {
        line-height: 20px;
        padding: 7px 20px 7px 14px;
    }
}

@media screen and (min-width:767px) and (max-width:1003px){
	body.resource-library.video-library.ps3-video.lynhcp-pro-integrate #videos.tab-pane.active.in>.grid:nth-child(2)>.clearfix {
	    display: flex;
	    align-items: flex-end;
	}
	.video-library .thumbnail .col-xs-12:nth-child(1) div.thumb {
	    margin-top: 0 !important;
	}
    #resources .hcp-res.resources-padding-lt .row {
	    padding-left: 20px;
	}
}

@media (min-width: 767px) {

    .resource-library .patient-res .pancreatic-column,
    .patient-res .pancreatic-column-1 {
        height: 100%;
        min-height: 185px;
    }

    .margin-right-45 {
        margin-right: 45px;
    }
}
@media screen and (min-width:992px) and (max-width: 1003px){
	.patient-profiles .william-opt p, .patient-profiles .joe-opt p {
    	padding: 24px 10px;
	}
    body.profound.safety-tolerability .pink_eyebrow,.safety-combination-theraphy .pink_eyebrow + .container-center.clinicalstudytxt, .monotherapy.safety-tolerability .clinicalstudytxt, body.monotherapy.profound.safety-tolerability.lynhcp-pro-integrate .section-one .footnotecontiner, body.monotherapy.profound.safety-tolerability.lynhcp-pro-integrate .section-one .footnotecontiner+.safetylistsect, .safety-combination-theraphy .pink_eyebrow, .neww-table.safety-olympia-table.sp1-table1, .safety-combination-theraphy .footnotecontiner.container-center, .safety-tolerability .section-two, .safety-combination-theraphy .footnotecontiner.container-center+.container-center.safetylistsect {
    	padding-left: 20px !important;
    	padding-right: 20px !important;
	}
}
@media screen and (min-width:991px) and (max-width:1360px){
	.patient-profiles .patient-ids .medical-hist.desktop.col-xs-12.col-sm-6 .joe-history {height: auto !important;}
}
@media screen and (min-width: 992px) and (max-width: 1250px){
    .patient-profiles .end-banner-patient {
        margin-top: 0 !important;
    }
}
@media screen and (min-width:768px) and (max-width:1003px) {
    .patient-profiles .tab-head-container {
        max-width: 93% !important;
        height: 89px !important;
        padding-bottom: 0 !important;
        padding-top: 0px !important;
    }

    .patient-profiles #tab-opener-2>a {
        padding: 8px 36px !important;
        max-width: 170px;
    }

    .patient-profiles .tab-head-container .tabs-body {
        align-items: flex-end;
    }

    .patient-profiles .tab-head-container .tabs-body .tab-links {
        margin-top: 22px;
    }

    .patient-profiles .tab-head-container .tab-heading h1 {
        max-width: 300px !important;
    }

    .patient-profiles #tab-opener-1>a {
        max-width: 180px !important;
    }
	.patient-profiles .mono-patient-profile .medical-hist {
	    padding: 0 10px;
	}
	.tab-pane.active.in#videos {
	    margin-top: 30px;
	}

	.tab-pane.active.in#videos .grid.section:nth-child(2) {
	    margin-top: 50px;
	}


	.tab-pane.active.in#videos .grid.section div#desc0 p.boldText.boldText-george {
	    margin-bottom: 0;
	}
}
@media (max-width: 991px) {


    .combination-therapy .section-two .footnotecontiner.container-center {
        margin-top: 20px !important;
    }

    .combination-therapy .section-two .cta-margin {
        margin-top: 24px !important;
    }

    .patient-profiles .mono-patient-profile .joe-history>div {
        margin-bottom: 5px;
    }

    .combination-therapy.safety-tolerability.safety-combination-theraphy.pc3-combi.lynhcp-pro-integrate .footnotecontiner.container-center {
        margin-top: 10px;
    }

    .monotherapy.profound.safety-tolerability.lynhcp-pro-integrate.safety-tolerability .section-two .footnotecontiner {
        margin-top: 10px;
    }

    .mobile.col-xs-12.col-sm-6.william-pot .william-opt {
        width: 95%;
    }

    /* QA issue */
    .treatment-paradigm .pink_eyebrow p,
    .safety-tolerability .pink_eyebrow p,
    .hrrm-testing .pink_eyebrow p {
        padding-right: 0%;
    }

    .patient-profiles .patient-profile-wrap {
        padding-bottom: 10px;
    }

    .pat-detail.pat-detail2 {
        padding-left: 0px;
    }

    .moa .sect-1 .img-cont {
        margin-bottom: 16px;
        margin-left: -5px;
    }

    .mechanism-of-action section.propel-content {
        margin-top: 24px;
        margin-bottom: 10px;
    }

    .moa .cta-margin {
        margin-top: 0px;
    }

    /*end QA Issues */
    .joe img.mobile {
        max-width: 278px;
    }

    .wiliam img.mobile {
        max-width: 330px;
    }
}

@media (min-width: 767px) {
    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .double-pan-column {
        /*width: 50%;*/
        width: 49%;
    }
}

@media (max-width: 767px) {
    .dosing-page .footnote {
  margin-left: 0 !important;
}

.dosing-page .reference .container-center.inner-wrapper {
  padding-left: 0;
}
    .resource-library .pan-col-head p {
        margin-bottom: 10px;
    }

    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .pancreatic-column,
    .pancreatic-column-1 {
        margin-top: 0px !important;
    }

    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .tab-links>nav a.nav-item {
        width: 105px !important;
    }

    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .box-image img {
        max-width: 115px;
        height: auto;
        object-fit: unset;
    }

    .moa.mechanism-of-action .pink_eyebrow,
    .safety-tolerability .pink_eyebrow,
    .hrrm-testing .pink_eyebrow {
        padding-top: 20px;
        padding-bottom: 20px;
    }

    .nccn-guidelines.lynhcp-pro-integrate .pink_eyebrow,
    .moa.mechanism-of-action .pink_eyebrow {
        padding-top: 21px;
        padding-bottom: 21px;
    }

    .moa.mechanism-of-action main#maincontent {
        margin-top: 120px !important;
    }

    /* QA issue */
    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .pancreatic-column,
    .pancreatic-column-1 {
        border-left: 0px;
        border-right: 0px;
        border-bottom: 0px;
    }

    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .pancreatic-column,
    .pancreatic-column-1:nth-child(3) {
        border-bottom: 1px solid #707070;
    }

    .col-xs-12.col-sm-6.double-pan-column.second-grid.box-col-1 {
        padding-left: 0px;
        padding-right: 0px;
    }

    .patient-res .double-pan-column.second-grid:nth-child(2),
    .patient-res .row:nth-child(3) .double-pan-column.second-grid {
        padding-top: 0px !important;
    }

    .patient-res .double-pan-column.second-grid {
        padding-top: 0px !important;
    }

    .down-res {
        padding-bottom: 15px !important;
    }

    .ps3-video .patient-res.resources-padding-lt {
        padding-left: 15px !important;
    }

    #resources .hcp-res.resources-padding-lt {
        padding-left: 20px !important;
    }

    #resources .down-res {
        padding-left: 15px !important;
        margin-bottom: -10px;
    }

    /* end QA issue */
}

@media screen and (min-width: 767px) and (max-width: 860px) {

    .resource-library .patient-res .pancreatic-column,
    .patient-res .pancreatic-column-1 {
        height: 100%;
        min-height: 215px !important;
    }
}

@media screen and (min-width: 320px) and (max-width: 350px) {

    .safety-tolerability .platinum_chart.mobile img {
        width: 280px !important;
    }

    .safety-combination-theraphy .pink_eyebrow h1.container-center {
        font-size: 24px;
        line-height: 30px;
    }

}


/*new table code */
.neww-table table tr td ul li:last-child .val {
    color: #59595B !important;
}

.neww-table tr:first-child th {
    border-bottom: 3px solid #56849f;
}

.neww-table .reaction-name {
    color: #2B2E34 !important;
    font-family: 'Roboto-Regular';
    font-size: 16px !important;
}

.neww-table tr:first-child th {
    text-align: center;
}

.neww-table tr:first-child th:first-child {
    text-align: left;
}

.neww-table {
    font-family: "Roboto-Bold";
    width: 100%;
    max-width: 100%;
    margin: 10px auto;
    margin-bottom: 20px;
    margin: 16px auto 35px auto;
    max-width: 1003px;
    width: 100%;
}

.monotherapy .neww-table {
    margin-bottom: 0px;
}

.monotherapy .section-one .footnotecontiner {
    margin-top: 5px;
}

.safety-tolerability .section-two .footnotecontiner {
    margin-top: 5px;
}

.safety-tolerability .section-two .neww-table {
    margin-bottom: 0px;
}

.section-two .neww-table {
    margin-bottom: 15px;
}

.neww-table table {
    border-collapse: collapse;
    width: 100%;
    background-color: #fff;
}

.neww-table tr:first-child th:first-child {
    padding-top: 12px;
    padding-bottom: 12px;
}

.neww-table td,
.neww-table th {
    border: 1px solid #c5c5c5;
    text-align: left;
    padding: 5px 8px;
    line-height: 22px;
    vertical-align: middle;
}

.neww-table th {
    font-weight: 600;
    font-size: 17px;
    line-height: 27px;
    font-family: "Roboto-Bold";
    color: #004D74;
    text-align: left;
}

.neww-table td {
    font-weight: 400;
    font-size: 17px;
    line-height: 23px;
    color: #2B2E34;
    font-family: "Roboto-Regular";
}

.table-legend {
    width: 100%;
    display: inline-block;
}

.table-legend ul {
    list-style: none;
    padding: 0;
    float: right;
    margin-top: 0;
    margin-bottom: 5px;
    display: flex;
    flex-direction: column;
}

.table-legend ul li {
    font-size: 16px;
    font-weight: 500;
    font-family: 'Roboto-Bold';
    color: #333;
    display: flex;
    align-items: center;
    margin-left: 16px;
    margin-top: 1px;
}

.table-legend ul li span {
    width: 18px;
    height: 18px;
    display: inline-block;
    margin-right: 8px;
}

.table-legend ul li:first-child span {
    background-color: #B2D234;
}

.table-legend ul li:last-child span {
    background-color: #56849f;
}

.table-legend ul li:first-child {
    color: #004D74;
}

.table-legend ul li:last-child {
    color: #a89e9b;
    color: #59595B;
}

.neww-table.paola-1-tab table thead tr:last-child {
    border-bottom: 3px solid #56849F;
}

.neww-table .reaction-name.pad-40 {
    padding-left: 40px;
}

@media screen and (max-width: 991px) {

    .monotherapy .section-7 tr th.symbol1 {
        font-size: 18px !important;
        line-height: 22px !important;
    }

    .combination-therapy .section-3 .ef-below-gragh-block p.last-note {
        margin-top: 7px !important;
    }

    .combination-therapy .section-2 .skew-maroon-head.sec71bg.sec71bg1 {
        margin-top: 24px !important;
    }

    .patient-profiles .mono-patient-profile p.fact-head {
        margin-bottom: 7px;
    }

    .neww-table .reaction-name.pad-40 {
        padding-left: 20px;
    }

    .neww-table.paola-1-tab td,
    .neww-table.paola-1-tab th {
        border: 1px solid #c5c5c5;
        text-align: left;
        padding: 4px 4px;
        line-height: 22px;
        vertical-align: middle;
        font-size: 13px;
        line-height: 21px;
        letter-spacing: -0.3px;
    }

    .table-legend ul {
        display: flex;
        justify-content: left;
        flex-direction: column;
        float: right;
    }

    .table-legend ul li {
        font-size: 9px;
        margin-left: 0;
        margin-bottom: 2px;
    }

    .neww-table th {
        font-size: 11px;
        line-height: 16px;
        letter-spacing: -0.4px;
    }

    .neww-table td {
        font-size: 14px;
        line-height: 21px;
    }

    .neww-table .reaction-name {
        font-size: 10px !important;
        line-height: 12px !important;
    }

    /* QA issue */
    .patient-profiles .med-facts {
        padding-bottom: 10px;
        padding-left: 15px;
    }

    #resources .col-xs-12.col-sm-6.second-grid {
        padding-left: 0px !important;
        padding-right: 0px !important;
    }

    .padd-bott20 {
        padding-bottom: 20px;
    }

    /* End QA issue */
}

@media screen and (min-width: 992px) {

    .patient-profiles .mono-patient-profile .med-facts ul {
        padding-left: 27px;
    }

    .combination-therapy .section-2 .ef-below-gragh-block p.padd-bot5 {
        letter-spacing: -0.1px;
    }

    .combination-therapy .section-2 .propel-content .skew-maroon-head {
        padding-right: 0px !important;
    }

    .combination-therapy .section-2 .propel-content .sec71bg {
        width: 97% !important;
    }

    .patient-profiles .combi-patient-profile .joe-history {
        height: 520px !important;
    }

    .neww-table th:nth-child(2),
    .neww-table th:last-child {
        width: 33%;
    }

    .neww-table.paola-1-tab tr td:first-child {
        padding-left: 8px;
    }

    /* QA issue */
    .patient-profiles .med-facts {
        margin-bottom: 27px;
    }

    .custom-split2 {
        width: 500px !important;
    }

    .patient-profiles .combi-patient-profile .joe-history {
        height: 535px;
    }

    .patient-profiles .combi-patient-profile .med-facts li {
        text-indent: 0px;
        margin-right: -5px;
    }

    .patient-profiles .mono-patient-profile .med-facts {
        margin-bottom: 40px;
        margin-right: 10px;
    }

    /*.patient-profiles .mono-patient-profile .med-facts:nth-child(3) {
        margin-bottom: 0px;
    }*/

    .moa .img-cont {
        margin-bottom: 10px !important;
    }

    .prostate-home #home-main-section .three-column-box>.box .box-body {
        padding-bottom: 16px;
    }

    .padd-bot5 {
        padding-bottom: 5px;
    }

    .padd-bot15 {
        padding-bottom: 15px;
    }

    .monotherapy.therapy>.flex-container .box-2-content {
        margin-top: -5px;
    }

    /*end QA Issues */

}

/* ================================================================================ */

ul.chart {
    list-style: none;
    padding: 0 !important;
    margin: 0;
}

ul.chart li {
    width: 100%;
    display: flex;
    flex-direction: row;
    align-items: center;
    margin: 2px auto;
}

.val {
    font-size: 16px;
    font-family: 'Roboto-Bold';
    width: 20%;
    min-width: 20px !important;
    display: inline-block;
    text-align: left;
    color: #004D74;
}

ul.chart-inverse li .val {
    text-align: right;
}

ul.chart li:first-child .val {
    color: #004D74;
}

ul.chart li:last-child .val {
    color: #004D74;
}

.bar {
    height: 16px;
    width: 100%;
    display: inline-block;
    background: transparent;
}

.bar span {
    width: 0;
    height: 100%;
    display: block;
    float: right;
}

ul.chart-inverse li .bar span {
    float: left;
}

ul.chart li:first-child .bar span {
    background-color: #B2D234;
}

ul.chart li:last-child .bar span {
    background: #56849f;
}

/* Bar width css start */
.bar span.w-83 {
    width: 83%;
}

.bar span.w-69 {
    width: 69%;
}

.bar span.w-89 {
    width: 89%;
}

.bar span.w-52 {
    width: 52%;
}

.bar span.w-48 {
    width: 48%;
}

.bar span.w-17 {
    width: 17%;
}

.bar span.w-5 {
    width: 5%;
}

.bar span.w-1 {
    width: 1%;
}

.bar span.w-11 {
    width: 11%;
}

.bar span.w-2 {
    width: 2%;
}

.bar span.w-7 {
    width: 7%;
}

.bar span.w-3 {
    width: 3%;
}

.bar span.w-40 {
    width: 40%;
}

.bar span.w-26 {
    width: 26%;
}

.bar span.w-25 {
    width: 25%;
}

.bar span.w-31 {
    width: 31%;
}

.bar span.w-27 {
    width: 27%;
}

.bar span.w-50 {
    width: 50%;
}

.bar span.w-58 {
    width: 58%;
}

.bar span.w-35 {
    width: 35%;
}

.bar span.w-30 {
    width: 30%;
}

.bar span.w-15 {
    width: 15%;
}

.bar span.w-21 {
    width: 21%;
}

.bar span.w-22 {
    width: 22%;
}

.bar span.w-37 {
    width: 37%;
}

.bar span.w-36 {
    width: 36%;
}

.bar span.w-20 {
    width: 20%;
}

.bar span.w-16 {
    width: 16%;
}

.bar span.w-4 {
    width: 4%;
}

.bar span.w-13 {
    width: 13%;
}

.bar span.w-9 {
    width: 9%;
}

.bar span.w-26 {
    width: 26%;
}

.bar span.w-71 {
    width: 71%;
}

.bar span.w-33 {
    width: 33%;
}

.bar span.w-82 {
    width: 82%;
}

.bar span.w-66 {
    width: 66%;
}

.bar span.w-70 {
    width: 70%;
}

.bar span.w-73 {
    width: 73%;
}

.bar span.w-63 {
    width: 63%;
}

.bar span.w-46 {
    width: 46%;
}

.bar span.w-65 {
    width: 65%;
}

.bar span.w-33 {
    width: 33%;
}

.bar span.w-28 {
    width: 28%;
}

.bar span.w-8 {
    width: 8%;
}

.bar span.w-23 {
    width: 23%;
}

.bar span.w-38 {
    width: 38%;
}

.bar span.w-3 {
    width: 3%;
}

.bar span.w-57 {
    width: 57%;
}

.bar span.w-18 {
    width: 18%;
}

.bar span.w-14 {
    width: 14%;
}

.bar span.w-10 {
    width: 10%;
}

.bar span.w-4-5 {
    width: 4.5%;
}

.bar span.w-42 {
    width: 42%;
}

.bar span.w-24 {
    width: 24%;
}

.bar span.w-3-9 {
    width: 3.9%;
}

.bar span.w-6 {
    width: 6%;
}

.bar span.w-12 {
    width: 12%;
}

.bar span.w-4-8 {
    width: 4.8%;
}

.bar span.w-0-8 {
    width: 0.8%;
}

.bar span.w-0-7 {
    width: 0.7%;
}

.bar span.w-0-3 {
    width: 0.3%;
}

.bar span.w-0-1 {
    width: 0.1%;
}

.bar span.w-1-8 {
    width: 1.8%;
}

.bar span.w-0-2 {
    width: 0.2%;
}

.bar span.w-77 {
    width: 77%;
}

.bar span.w-59 {
    width: 59%;
}

.bar span.w-64 {
    width: 64%;
}

.bar span.w-67 {
    width: 67%;
}

.bar span.w-41 {
    width: 41%;
}

.bar span.w-47 {
    width: 47%;
}

.bar span.w-39 {
    width: 39%;
}

.bar span.w-79 {
    width: 79%;
}

.bar span.w-76 {
    width: 76%;
}

.bar span.w-55 {
    width: 55%;
}

.bar span.w-44 {
    width: 44%;
}

.bar span.w-87 {
    width: 87%;
}

.bar span.w-19 {
    width: 19%;
}

.bar span.w-43 {
    width: 43%;
}

.bar span.w-51 {
    width: 51%;
}

.bar span.w-34 {
    width: 34%;
}

.bar span.w-45 {
    width: 45%;
}

.bar span.w-29 {
    width: 29%;
}

.bar span.w-61 {
    width: 61%;
}

.bar span.w-3-7 {
    width: 3.7%;
}

.bar span.w-3-4 {
    width: 3.4%;
}

.bar span.w-2-2 {
    width: 2.2%;
}

.bar span.w-1-9 {
    width: 1.9%;
}

.bar span.w-1-5 {
    width: 1.5%;
}

.bar span.w-0-9 {
    width: 0.9%;
}

.bar span.w-0-4 {
    width: 0.4%;
}

.bar span.w-1-5 {
    width: 1.5%;
}

.bar span.w-1-7 {
    width: 1.7%;
}

.bar span.w-1-9 {
    width: 1.9%;
}

.bar span.w-2-4 {
    width: 2.4%;
}

.bar span.w-1-1 {
    width: 1.1%;
}

.bar span.w-53 {
    width: 53%;
}

.bar span.w-32 {
    width: 32%;
}

.bar span.w-3-3 {
    width: 3.3%;
}

.bar span.w-2-3 {
    width: 2.3%;
}

.bar span.w-0 {
    width: 0%;
}

.bar span.w-0-5 {
    width: 0.5%;
}

.bar span.w-1-3 {
    width: 1.3%;
}

.bar span.w-1-2 {
    width: 1.2%;
}

.bar span.w-97 {
    width: 97%;
}

.bar span.w-81 {
    width: 81%;
}

.bar span.w-49 {
    width: 49%;
}

.bar span.w-98 {
    width: 98%;
}

.bar span.w-62 {
    width: 62%;
}


/* Bar width css start */
.neww-table.dosing-c-tab table thead tr:last-child {
    border-bottom: 3px solid #56849F;
}

.neww-table.dosing-c-tab th {
    font-weight: 600;
    font-size: 20px;
    line-height: 28px;
    font-family: "Roboto-Bold";
    color: #004D74;
    text-align: center;
}

.neww-table.dosing-c-tab td {
    font-weight: 600;
    font-size: 20px;
    line-height: 28px;
    font-family: "Roboto-Bold";
    color: #2B2E34;
    text-align: left;
}

@media screen and (max-width: 991px) {
    .patient-profiles .mobile.william-history .med-facts ul p:nth-child(1) {
        margin-bottom: 5px !important;
    }

    .moa .space1 {
        padding-left: 0px;
    }

    .moa .pink_eyebrow .container-center,
    .nccn-guidelines .pink_eyebrow div.container-center {
        padding-left: 20px;
        padding-right: 20px;
    }

    .moa .moa-combi .sect-1 {
        padding: 0px 20px;
    }

    .dosing-page #maincontent .therapy>.flex-container .lynparza>p:nth-child(3) span.text-nowrap {
        white-space: normal;
    }

    .monotherapy .section-one .footnotecontiner {
        margin-top: 15px;
    }

    .moa-combi .sect-1 .heading-1 {
        margin-bottom: 8px;
    }

    .resource-library.video-library.ps3-video.lynhcp-pro-integrate #sitemap .isi .isi-body {
        padding-top: 135px !important;
    }

    .resource-library #maincontent .container-center {
        padding-top: 17px;
        margin-bottom: 0;
    }

    .video-library .thumbnail .col-xs-12:nth-child(2) .thumb-head {
        margin-top: 34px;
    }

    .patient-profiles.lynhcp-pro-integrate #footer .combi-foots .reference.container-center {
        margin-bottom: 24px;
    }

    .monotherapy .table-legend ul li {
        flex-direction: row-reverse;
    }

    .monotherapy .table-legend ul li span {
        margin-right: 0px;
        margin-left: 8px;
    }

    .monotherapy .cta-button a:after {
        margin-left: 15px;
    }

    .monotherapy .cta-margin .cta-button a {
        padding: 17px 25px;
    }

    .monotherapy.safety-tolerability .section-two .clinicalstudytxt {
        margin-top: 55px !important;
    }

    .monotherapy .section-one .safetylistsect {
        margin-top: 15px !important;
    }

    .monotherapy .safetylistsect ul {
        padding-left: 31px !important;
        line-height: 18px;
        font-size: 14px;
    }

    .safety-combination-theraphy .safetylistsect ul {
        padding-left: 28px !important;
    }

    .patient-profiles .combi-patient-profile .skew-maroon-head {
        margin-bottom: 22px !important;
    }

    .combi-patient-profile .cta-margin {
        margin-top: 22px;
    }

    .nccn-guidelines.lynhcp-pro-integrate .sec-two .label-heading p {
        margin-bottom: 7px;
    }

    .nccn-guidelines.lynhcp-pro-integrate .label-heading p {
        padding: 1px 24px 0px 8px;
        margin-bottom: 15px;
    }

    .nccn-guidelines.lynhcp-pro-integrate .card-content {
        padding: 0px 24px 0px 8px;
    }

    .nccn-guidelines.lynhcp-pro-integrate .sec-two .card-content {
        padding: 0px 8px 0px 8px;
    }

    .neww-table {
        width: 90%;
        margin: 18px auto 0px;
    }

    .neww-table.efficacy-table {
        width: 100% !important;
        margin: 18px auto 0px;
    }

    .val {
        font-size: 10px;
        line-height: 12px;
    }

    .sp1-table3 .table-legend>ul li {
        background-color: #B2D234;
        text-align: center;
        font-size: 16px !important;
        line-height: 20px;
    }

    .table-legend ul li:last-child {
        color: #a89e9b;
        color: #59595B;
    }

    td.border-left-none.indented-data {
        padding-left: 14px !important;
        padding-right: 4px !important;
    }

    .efficacy-table .reaction-name {
        font-size: 11px !important;
        line-height: 16px !important;
    }

    .neww-table.efficacy-table .reaction-name {
        font-size: 12px !important;
        line-height: 16px !important;
    }

}

@media screen and (min-width: 992px) {

    /*staging 1 issues*/
    .patient-profiles .combi-patient-profile .pat-detail .curr-age {
        margin-bottom: 10px;
    }

    /*staging 1 issues*/
    .monotherapy .safetylistsect ul,
    .combination-therapy .safetylistsect ul {
        margin-left: -2.6%;
        padding-right: 4px;
    }

    .patient-profiles .cta-margin {
        margin-bottom: -10px;
        margin-top: 30px;
    }

    body.profound.safety-tolerability .pink_eyebrow,
    .dosing-page .common-headline {
        padding-top: 54px !important;
    }

    .neww-table tr th:first-child,
    .neww-table tr td:first-child {
        padding-left: 20px;
    }

    td.border-left-none.indented-data {
        padding-left: 24px !important;
        padding-right: 6px !important;
    }

    .propel-content .section-71 .skew-maroon-head h2 {
        padding: 5px 10px 5px 0px;
    }
}

/*end new table code */

/* efficancy table code */
.neww-table.efficacy-table {
    font-family: "Roboto-Bold";
    margin: 37px 0px 35px 0px;
    max-width: 895px;
    width: 100%;
}

.neww-table.efficacy-table tr:first-child th:first-child {
    padding-top: 7px;
    padding-bottom: 7px;
}

.efficacy-table tr:nth-child(9) th {
    color: #ffffff;
}

th.border-none {
    border: unset !important;
}

.white-border {
    border: 2px solid #fff !important;
}

.light-gray {
    background-color: #cbcaca61;
}

.text-center {
    text-align: center !important;
}

.efficacy-table tr:first-child th {
    border-bottom: 1px solid #c5c5c5;
    border-top: 1px solid #c5c5c5;
}

th.pad-0 {
    padding: 0px;
}

.efficacy-table .reaction-name {
    font-family: 'Roboto-Regular';
    font-size: 18px !important;
    line-height: 20px !important;
    padding: 16px 2px;
}

th.heading-text {
    text-align: center;
    font-weight: 600;
    font-size: 17px;
    line-height: 27px;
    font-family: "Roboto-Bold";
    color: #000000;
    background: #A9ACAF;
    padding: 12px 0px;
}

.sub-heading {
    color: #2B2E34 !important;
    font-family: 'Roboto-Regular';
    font-size: 16px !important;
    line-height: 20px !important;
}

th.reaction-name.bg-blue {
    background: #004D74;
    color: #fff !important;
}

.efficacy-table table th {
    width: 25% !important;
}

.light-pink {
    background: #D9B9CA;
    border-top: 1px solid #a9acaf !important;
    border-bottom: 1px solid #a9acaf !important;
}

th.reaction-name.table-pink-color {
    color: #990064 !important;
}

.reaction-name.brg-pink {
    background: #990064;
    color: #fff !important;
}

.white-top-border {
    border-top: 2px solid #fff !important;
}

.white-left-border {
    border-left: 2px solid #fff !important;
}

.white-right-border {
    border-right: 2px solid #fff !important;
}

.white-bottom-border {
    border-top: 2px solid #fff !important;
}

.black-top-border {
    border-top: 2px solid #000 !important;
}

.border-bottom-none {
    border-bottom: none !important;
}

.border-right-none {
    border-right: none !important;
}

.border-left-none {
    border-left: none !important;
}

/*end efficancy table code*/

@media screen and (max-width:350px){
    body.patient-profiles #tab-opener-2 > a {
        padding-top: 9px;
        padding-bottom: 9px;
    }
    
    body.patient-profiles .wiliam img.mobile {
        max-width: 270px;
    }
    .patient-profiles #tab-opener-1 > a {
	    padding-right: 10px !important;
	    padding-left: 10px !important;
	    padding-top: 9px !important;
	}
}
@media screen and (max-width:374px){
    .resource-library.video-library.ps3-video.lynhcp-pro-integrate .tab-links>nav a.nav-item {
	    width: 90px !important;
	    font-size: 16px;
	}
}

/* US-108107 update starts */

@media screen and (max-width:1003px){
.resource-library.video-library.ps3-video.lynhcp-pro-integrate #sitemap .isi .isi-body {
    padding-top: 20px !important;
}
    #resources .down-res {

        padding-right: 15px !important;
                                        }
}

 /* compatibility code */

   @media screen and (min-width:991px) and (max-width:1003px){
    .resource-library-update #resources .hcp-res.resources-padding-lt .row

 {
                                            padding-left:0px!important;}
 }



@media screen and (min-width:1004px) and (max-width:1055px){
                                        .resource-library-update .hcp-res.resources-padding-lt {
                                                        padding-left: 0px !important;}


}

@media screen and (min-width:1055px) and (max-width:1100px){
                                        .resource-library-update .hcp-res.resources-padding-lt {
                                                        padding-left: 15px !important;
 margin-left: 0px !important;

                                                                }


}

@media screen and (min-width: 767px) and (max-width: 819px) {
    .video-library .tab-links {
    margin-top: 24px !important;
}
}