@font-face {
  font-family: 'Roboto-Black';
  src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black.eot');
  src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black.eot?#iefix') format('embedded-opentype'),
    url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black.woff2') format('woff2'),
    url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black.woff') format('woff'),
    url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black.ttf') format('truetype'),
    url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black.svg#Roboto-Black') format('svg');
  font-weight: 900;
  font-style: normal;
  font-display: swap;
}

/* ************************************************** */
.propel-home-update-q1 .in-page-header .new-connect-rep-button>div a:hover {
  color: white;
}

.pros-update-text-margin {
  margin-bottom: 0 !important;
}

.pros-update-lime-clr-text {
  color: #B2D234;
}

.pros-update-efficacy-banner .banner-section-3.pink-bg .flex-container .box.box-1.image-container img {
  width: 292px;
  left: -27px;
}

.efficacy-mono-banner.pros-update-efficacy-banner-monotherapy .banner-section-3.pink-bg .flex-container .box.box-1.image-container img {
  width: 294px;
  left: -30px;
}

.efficacy-mono.section-8.lt-grey-bg.pros-update-study-design .img-sec img {
  width: 100%;
}

/* .testing.section-2.pros-table-update ul.list-section li.list-item:nth-child(2) .list-bullet {
    top: 0px;
}

.testing.section-2.pros-table-update ul.list-section li.list-item .list-bullet {
    top: 5px;
} */

body.prostrate_efficacy .efficacy-mono-banner.pros-update-efficacy-banner-monotherapy .banner-section-3 .box.box-1.image-container p.not-real-patient {
  color: #000000;
}

.margin-right-pros {
  margin-right: 2px;
}

.margin-right-pros-4 {
  margin-right: 4px;
}

body.prostrate_efficacy .section-6.pros-update-section-6 .efficacy-graph-container .graph-data ul+p {
  max-width: 100%;
  font-size: 16px;
  line-height: 20px;
  color: #333333;

}

body.prostrate_efficacy .section-6.pros-update-section-6 .efficacy-graph-container .graph-data ul.list-section.second-ul {
  margin-top: 0;
  margin-bottom: 0;
}

/* ************************************************** */
.pr-tumor-type .reference a,
.pr-tumor-type .reference-container a {
  color: inherit;
  pointer-events: none;
}

.propel-home-banner {
  background: transparent linear-gradient(177deg, #990064 35%, #99006400 95%) 0% 0% no-repeat padding-box;
}

.home-combination {
  max-width: 1366px;
  margin: 0 auto;
  background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/pros-update-q1/desktop/home-combination-banner.png);
  background-repeat: no-repeat;
  background-position-y: bottom;
}

.home-combination .combination-container,
.home-mono .home-mono-container {
  max-width: 1010px;
  margin: 0 auto;
}

.home-combination .combination-container .section-1 {
  max-width: 724PX;
  margin: 0 0 0 auto;
  padding-top: 94px;
}

.testing.section-3 .pie-chart-container.pie-chart-2 ul li.footnotes:not(:first-child) {
  margin-top: 0;
}

.section-4.testing .table .flex-container .box-1 img {
  width: 100%;
}

.ef-below-gragh-block ul.list-graph {
  padding-left: 17px;
}

.home-combination .combination-container .section-1 .section-heading {
  margin: 0;
  font-size: 34px;
  line-height: 44px;
}

.home-combination .combination-container .section-1 .section-subhead {
  font-size: 18px;
  line-height: 24px;
  margin: 10px 0 38px;
  max-width: 630PX;
}

.propel-home-banner .not-actual-text {
  font-size: 16px;
  line-height: 16px;
}

.flex-box.section-2 {
  display: flex;
  align-items: center;
  margin: 10px 0 14px;
  justify-content: space-between;
}

.flag-image img {
  max-width: 341px;
  margin-bottom: 5px;
}

.skew-heading {
  overflow: hidden;
  border-left: 2px solid white;
  margin-bottom: 5px;
}

.home-eyebrow-head p>span {
  padding: 9px;
  font-size: 20px;
  line-height: 24px;
  display: inline-block;
  border: 3px solid white;
}

.home-eyebrow-head p>span>span {
  display: inline-block;
}

.home-eyebrow-head p>span.pink-bg {
  padding-left: 16px;
}

.white-bg {
  background-color: white;
}

.propel-home-banner p {
  margin: unset;
}

.home-eyebrow-head {
  margin-left: -10px;
  transform: skew(-4deg);
}

.home-eyebrow-subhead {
  font-size: 20px;
  line-height: 24px;
}

.flex-box.section-2 .box-1 {
  max-width: 696px;
  width: 100%;
}

.flex-box.section-2 .box-2 {
  max-width: 266px;
  width: 100%;
  text-align: center;
}

.flex-box.section-2 .box-2 p {
  margin-bottom: 10px;
}

.section-3.flex-box {
  display: flex;
  padding: 0 2.5px;
  justify-content: space-between;
}

.section-3.flex-box .card {
  background-color: #F5E6F0;
  max-width: 490px;
  width: 100%;
  display: flex;
  flex-direction: column;
  justify-content: space-between;
  padding: 14px 18px 21px 17px;
}

.ff-roboto-medium {
  font-family: 'Roboto-Medium';
}

.ff-roboto-black {
  font-family: 'Roboto-black' !important;
  /* font-weight: 900; */
}

.section-3.flex-box .card .card-content>p {
  font-size: 18px;
  line-height: 24px;
}

.section-3.flex-box .card .card-content .flex-content {
  display: flex;
  justify-content: space-between;
  gap: 9px;
  margin-bottom: 12px;
}

.section-3.flex-box .card .card-content .flex-content .percentage {
  max-width: 98px;
  width: 100%;
}

.section-3.flex-box .card .card-content .flex-content .percentage p {
  font-size: 60px;
  line-height: 60px;
  letter-spacing: -3.84px;
}


.section-3.flex-box .card .card-content .flex-content .content p {
  font-size: 20px;
  margin-bottom: 3px;
  line-height: 24px;
}

.section-3.flex-box .card .card-content .flex-content .content p:nth-child(2n),
.section-3.flex-box .card .card-content .flex-content .content p:nth-child(5) {
  font-size: 16px;
  line-height: 19px;
}

.section-3.flex-box .card .card-content .flex-content .content p:nth-child(5) {
  margin-top: 10px;
}

.section-3.flex-box .card .card-content .flex-content .content .data {
  padding-right: 7px;
}

.section-3.flex-box .card.card-2 .card-content .flex-content .content .data {
  padding-right: 15px;
}

.section-3.flex-box .card-link {
  text-align: right;
}

.card-link a {
  display: inline-block;
  max-width: 257px;
  width: 100%;
  text-align: center;
  border-radius: 7px;
  border: 2px solid #990064;
  font-family: 'Roboto-Bold';
  padding: 12.5px 0;
}


.card-link a:after {
  content: "";
  display: inline-block;
  background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/pros-update-q1/global/right-arrow-pink.png);
  width: 12px;
  height: 12px;
  background-size: cover;
  background-repeat: no-repeat;
  vertical-align: middle;
  margin-left: 9px;
}

.combination-container .comb-ref-links {
  max-width: 607px;
  margin: 10px 0 0 auto;
}

.pros-footnote {
  font-size: 13px;
  line-height: 16px;
}

.combination-container .comb-ref-links .comb-links {
  padding: 0;
  list-style: none;
  display: flex;
  gap: 27px;
  margin: 0;
  padding: 10px 0 15px;
}

.combination-container .comb-ref-links .comb-links li a {
  color: black;
  font-size: 13px;
  line-height: 16px;
}

.propel-home-banner .home-mono {
  border-top: 6px solid #990064;
  border-bottom: 6px solid #990064;
}

.home-mono .home-mono-container {
  padding-top: 0;
  display: flex;
  margin-top: 22px;
}

.home-mono-container .mono-content .home-eyebrow-subhead.mono-section-head {
  margin: 5px 0 8px;
}

.home-mono .mono-card {
  max-width: 490px;
  border: 1px solid #707070;
  padding: 15px 26px;
  margin-bottom: 10px;
}

.home-mono .mono-card .card-link {
  margin: 13px 0 22px;
}

.home-mono .mono-card>.home-eyebrow-subhead {
  margin-bottom: 7px;
}

.home-mono .mono-card .card-link>a {
  background-color: #F3E8EE;
}

.propel-home-banner .home-mono .not-actual-text {
  max-width: 489px;
  text-align: right;
  margin-bottom: 7px;
}

.home-mono .home-mono-container .mono-content {
  padding-top: 6px;
}

.home-mono .home-mono-container .mono-image {
  display: flex;
}

.home.prostate-home .nccn-section {
  max-width: 1004px;
  margin: 0 auto;
}

.home.prostate-home .nccn-section .nccn-container {
  background-color: #E5EDF0;
  margin: 24px 0;
  padding: 12px 18px 12px 15px;
}

.home.prostate-home .nccn-section .nccn-container>p:first-child {
  font-size: 32px;
  line-height: 50px;
}

.home.prostate-home .nccn-section .nccn-container>p:nth-child(2) {
  margin: 10px 0 12px;
}


.home.prostate-home .nccn-section .nccn-container .flex-box {
  display: flex;
  justify-content: space-between;
}

.home.prostate-home .nccn-section .nccn-container .flex-box p.card-link a {
  max-width: 282px;
  width: 100%;
  border-color: #004D74;
}

.home.prostate-home .nccn-section .nccn-container .flex-box .pros-footnote {
  margin: 0;
  max-width: 549px;
  width: 100%;
  margin-top: 21px;
}

.home.prostate-home .nccn-section .nccn-container .flex-box p.card-link {
  width: 100%;
  max-width: 282px;
  margin: 0 24px 4px 0;
}

.home.prostate-home .nccn-section .nccn-container .flex-box p.card-link a:after {
  background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/pros-update-q1/global/right-arrow-blue.png);
}

.parpi-section .flex-box.parpi-img-section {
  display: flex;
  justify-content: space-between;
  margin-bottom: 13px;
}

.parpi-section .flex-box.parpi-img-section img {
  width: 100%;
}

.parpi-section .flex-box.parpi-img-section>* {
  max-width: 496px;
  width: 100%;
}

.card-link a:hover {
  background-color: #990064 !important;
  color: white !important;
  text-decoration: underline;
}

.card-link a:hover:after {
  background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/pros-update-q1/global/right-arrow-white.png) !important;
}

.home.prostate-home .nccn-section .nccn-container .flex-box p.card-link a:hover {
  background-color: #004D74 !important;
  color: white !important;
}

.home-mono .flag-image img {
  max-width: 287px;
  margin-top: 9px;
}

/* Patient -care page starts */

.patient-profiles .tab-head-container.propel-update-q1 {
  margin: 0;
  max-width: 100%;
  transform: none;
  height: auto;
  padding: 34px 0 0;
}

.patient-profiles .tab-head-container.propel-update-q1 .tabs-body {
  transform: none;
  max-width: 1005px;
  margin: 0 auto;
  flex-direction: column;
}

.patient-profiles .propel-update-q1 .tab-links .link-parent {
  transform: none;
  width: 100%;
  max-width: 248px;
}

.patient-profiles .propel-update-q1 .tab-links>nav>.nav-tabs {
  display: flex;
  justify-content: flex-end;
}

.patient-profiles .tab-head-container.propel-update-q1 .tab-heading h1 {
  margin: 0;
  max-width: 786px;
  font-size: 36px;
  line-height: 43px;
}


.patient-profiles .propel-update-q1 #tab-opener-1>a,
.patient-profiles .propel-update-q1 #tab-opener-2>a {
  color: rgba(128, 24, 82, 0.35);
  max-width: 248px;
  width: 100%;
  padding: 12.5px;
  display: inline-block;
}

.patient-profiles .propel-update-q1 #tab-opener-2>a {
  background-color: #F3E8EE !important;
}

.patient-profiles #tab-opener-1>a {
  background-color: #FFFFFF;
}

.patient-profiles .combination-therapy {
  max-width: 1005px;
  margin: 0 auto;
}

.patient-profiles .patient-image img {
  width: 100%;
  max-width: 475px;
}

.patient-profiles .section-head p {
  font-size: 30px;
  line-height: 38px;
  padding: 22px 0 20px;
  margin: 0;
}

.patient-profiles .detaials-list-heading {
  margin: 0;
  font-size: 24px;
  line-height: 38px;
  position: relative;
}

.patient-profiles .patient-heading {
  margin-bottom: 10px;
}

.patient-profiles .flex-box.patient {
  display: flex;
  column-gap: 54px;
}

.patient-profiles .flex-box.patient .box {
  max-width: 475px;
  width: 100%;
}

.patient-profiles .combination-therapy .flex-box.patient .box-2 {
  max-width: 466px;
  padding-left: 33px;
  padding-top: 40px;
}

.patient-profiles .patient-details-list ul {
  padding: 0;
  list-style: none;
  margin-bottom: 18px;
}

.patient-profiles .patient-details-list ul li {
  padding-left: 11px;
  position: relative;
  font-size: 20px;
  line-height: 26px;
  font-family: 'Roboto-Regular';
}

.patient-profiles .patient-details-list ul li:before {
  content: "";
  display: inline-block;
  width: 4px;
  height: 4px;
  background-color: black;
  border-radius: 10px;
  position: absolute;
  left: 0;
  top: 10px;
}

.patient-profiles .patient-details-list ul.small-list li {
  font-size: 16px;
  line-height: 22px;
}

.patient-profiles .patient-image {
  margin-bottom: 13px;
}

.patient-profiles .patient-details-list ul li ul.patient-details-sublist {
  padding-left: 39px;
  margin: 0;
}

.patient-profiles .patient-details-list ul li ul.patient-details-sublist li:before {
  content: "–";
  background: none;
  width: auto;
  height: auto;
  top: 0;
  left: -5px;
  font-family: 'Roboto-Regular';
}

.patient-profiles .detaials-list-heading.pink-ball:before {
  content: "";
  position: absolute;
  width: 23px;
  height: 23px;
  background: #990064;
  left: -33px;
  border-radius: 50%;
  top: 7px;
}

.patient-profiles .skew-desc {
  max-width: 475px;
  margin: 42px auto 36px;
}

.patient-profiles .skew-desc p {
  font-size: 18px;
  line-height: 23px;
  text-align: center;
  padding: 16px;
}

.patient-profiles .cta-button {
  text-align: center;
  display: inline-block;
}

.patient-profiles .cta-button a span {
  display: inline-block;
}

.patient-profiles .cta-button a:after {
  margin: 0 3px;
}

.patient-profiles .cta-button a {
  max-width: 312px;
  padding: 15.5px 0;
  background-color: #F5E6F0;
}

.patient-profiles .mono-patient-profile .monotherapy {
  max-width: 1005px;
  margin: 0 auto;
}



.patient-profiles .monotherapy .patient-details-list:has(.pink-ball) {
  padding-left: 33px;
  padding-right: 15px;
}

.patient-profiles .mono-patient-profile .bg-color {
  background-color: #F3E8EE;
}

.patient-profiles .mono-patient-profile .cta-button a {
  background-color: #004D741A;
}

.patient-profiles .mono-patient-profile .cta-button a:hover {
  background-color: #004D74;
}

/* Patient -care page ends */
.deskop-inline-block {
  display: inline-block;
}

.mobile-inline-block {
  display: none;
}


body.combination-therapy #propel-rpfs,
body.combination-therapy #propel-p3,
body.combination-therapy #propel-os {
  scroll-margin-top: 150px;
}

body.prostrate_efficacy .maincontent p.eff-comb-update {
  font-size: 16px;
  line-height: 20px;
  margin-bottom: 5px;
}

.efficacy-mono.section-7 .table-content {
  display: none;
}

/* Dosing starts */

.section-2.dosing .combination .box-1 {
  background-color: #F3F8E0;
  border: 1px solid #B2D234;
  max-width: 433px;
  width: 100%;
  padding: 0 30px 0 45px;
  position: relative;
  left: -30px;
  margin-right: -50px;
}



.section-2.dosing .combination .box-2 {
  background-color: #56849F;
  padding: 5px 33px 4px 49px;
  right: -30px;
  position: relative;
  max-width: 665px;
  width: 100%;
}

.section-2.dosing .combination .box-2 .abiraterone-new {
  padding: 0;
  position: relative;
}

.dosing #maincontent .combination .section-container p.devider-line {
  margin: 0;
  position: relative;
  margin-right: 8px;
  display: flex;
  align-items: center;
  column-gap: 17px;
  font-size: 13px;
  line-height: 13px;
  letter-spacing: -0.13px;
}

.dosing #maincontent .combination .section-container p.devider-line:before,
.dosing #maincontent .combination .section-container p.devider-line:after {
  content: "";
  height: 1px;
  display: inline-block;
  width: 100%;
  max-width: 445px;
  background-color: white;
  top: 50%;
  right: 0;
}

.dosing #maincontent .combination .section-container p.devider-line:before {
  max-width: 34px;
}

.dosing #maincontent .propel-update-dosing-comb .flex-box {
  display: flex;
}

.dosing #maincontent .propel-update-dosing-comb .main-heading {
  font-size: 21.5px;
  line-height: 29px;
  font-family: 'Roboto-Black';
}

.dosing #maincontent .propel-update-dosing-comb .sub-heading {
  font-size: 16.5px;
  line-height: 21px;
  letter-spacing: -0.17px;
}

.dosing #maincontent .propel-update-dosing-comb .card-side-head {
  font-size: 15.5px;
  line-height: 18px;
  letter-spacing: -0.31px;
}

.dosing #maincontent .propel-update-dosing-comb .capsule-box .capusles {
  display: flex;
  flex-direction: column;
  gap: 5px;
}

.dosing #maincontent .propel-update-dosing-comb .capsule-box {
  align-items: center;
  gap: 10px;
}

.dosing #maincontent .propel-update-dosing-comb .capsule-box .capusles span {
  border-radius: 30px;
  display: inline-block;
  max-width: 69px;
  padding: 3px 8px;
  font-weight: bold;
  font-size: 16px;
  line-height: 22px;
  width: 100%;
  text-align: center;
}

.dosing #maincontent .propel-update-dosing-comb .daily-dosage-text p {
  font-size: 17px;
  line-height: 23px;
}

.dosing #maincontent .propel-update-dosing-comb .box-1 .daily-dosage-text p {
  font-size: 22px;
  line-height: 29px;
}

.dosing #maincontent .propel-update-dosing-comb .flex-box.precaution {
  align-items: baseline;
}

.dosing #maincontent .propel-update-dosing-comb .card-side-head+.flex-box {
  /* justify-content: space-between; */
  gap: 25px;
}

.dosing #maincontent .propel-update-dosing-comb .flex-box.precaution .with-precaution p {
  font-size: 12px;
  line-height: 16px;
}

.dosing #maincontent .propel-update-dosing-comb .flex-box.precaution .with-precaution {
  text-align: center;
}

.dosing #maincontent .propel-update-dosing-comb .flex-box-new>.flex-box {
  column-gap: 20px;
}

.dosing #maincontent .propel-update-dosing-comb .box-2 .capsule-box .capusles {
  flex-direction: row;
}

.dosing #maincontent .propel-update-dosing-comb .box-2 .capsule-box .capusles .skyblue-bg {
  background-color: #8DC2E0;
}

.dosing #maincontent .propel-update-dosing-comb .card-normal-text {
  font-size: 12.5px;
  line-height: 16px;
  letter-spacing: -0.46px;
}



.dosing #maincontent .propel-update-dosing-comb .box-2 .flex-box.precaution .with-precaution p {
  font-size: 11.5px;
  line-height: 12px;
}

.dosing #maincontent .propel-update-dosing-comb .flex-box.single-dosage {
  gap: 20px;
}

.dosing #maincontent .propel-update-dosing-comb .flex-box.single-dosage .lt-skyblue-bg {
  background-color: rgb(229, 236, 240);
  width: 69px;
  text-align: center;
}

.dosing #maincontent .propel-update-dosing-comb .card-footnote p {
  font-size: 11.5px;
  line-height: 15px;
}

.section-2.dosing .combination .box-2:before {
  content: "";
  position: absolute;
  width: 66px;
  height: 66px;
  background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/update-prostate/desktop/dosing/plus-sign.svg);
  background-size: contain;
  background-repeat: no-repeat;
  left: 0;
  top: 50%;
  transform: skewX(10deg) translate(-50%, -50%);
}

.section-2.dosing .combination .part-two .box-1 {
  margin: 0;
  max-width: 100%;
  background-color: #E6ECEF;
  border-color: #004D74;
  padding: 2px 0 30px 31px;
  left: -21px;
  display: flex;
  align-items: center;
}

.section-2.dosing .combination .part-two .box-new-2 {
  max-width: 416px;
  margin-top: -25px;
  padding-left: 6px;
}

.section-2.dosing .combination .part-two .box-1>.lynparza {
  display: flex;
  align-items: flex-end;
  column-gap: 20px;
}

.section-2.dosing .combination .part-two .box-1>.lynparza .flex-box-2 {
  max-width: 192px;
}

.dosing #maincontent .propel-update-dosing-comb .flex-box.part-two {
  align-items: unset;
}

.section-2.dosing .combination .part-two .box-1>.lynparza>.flex-box {
  gap: 20px;
}



.dosing-page #maincontent .therapy .section-heading p {
  font-size: 13px;
  line-height: 16px;
  padding-left: 22px;
}



#maincontent .section-2.dosing .combination .part-two .box-new-2 p {
  color: #525252;
  font-size: 14px;
  line-height: 14px;
  letter-spacing: -0.28px;
  margin-bottom: 5px;
}

#maincontent .section-2.dosing .combination .part-two .box-new-2 .section-content p:nth-child(2) {
  letter-spacing: -0.34px;
}

#maincontent .section-2.dosing .combination .part-two .box-new-2 .section-content .contnet-heading {
  font-size: 15px;
  line-height: 15px;
}

.dosing .therapy .section-heading {
  margin: 0 0 7px -7px;
}

.dosing #maincontent .propel-update-section-4 .section-heading-new p {
  font-size: 18px;
  line-height: 20px;
  margin-bottom: 13px;
}

.dosing .propel-update-section-4 .green-flex {
  gap: 8px;
  margin-bottom: 13px;
}

.dosing .propel-update-section-4 .green-flex .box-2 {
  max-width: 697px;
}

.dosing .propel-update-section-4 .green-flex .box-1 {
  max-width: 293px;
}

.dosing .propel-update-section-4 .green-flex .box-2 .skew-flex {
  justify-content: center;
  gap: 10px;
}

.dosing .propel-update-section-4 .green-flex .box-1:after {
  right: -7px;
  font-family: 'Roboto-Bold', sans-serif;
  color: #B2D234;
  background-color: #004D74;
  padding: 2px 11px;
  transform: skewX(-10deg) translateX(50%);
  top: 0;
  z-index: 1;
  font-size: 20px;
  line-height: 27px;
}



.dosing .propel-update-section-4 .green-flex .box-1 .box-content {
  padding: 0 37px;
}

.dosing #maincontent .propel-update-section-4 .dosing-callouts .green-flex p.box-subhead {
  font-size: 16px;
  line-height: 20px;
  margin: 0;
  text-align: center;
  max-width: 100%;
}

.dosing #maincontent .propel-update-section-4 .green-flex .box .box-heading p {
  padding: 1.5px;
  font-size: 17px;
  line-height: 28px;
}

.dosing .propel-update-section-4 .green-flex .box .box-content {
  margin-top: 0;
  min-height: auto;
  background-color: transparent;
}

.dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards {
  margin: 10px 0 0;
  max-width: 312px;
  padding: 12px 20px;
}

.dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards .propel-flex {
  display: flex;
  align-items: baseline;
  gap: 15px;
}

.dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards .propel-flex .flex-container {
  flex-direction: column;
  gap: 4px;
  align-items: flex-start;
}

.dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards .propel-flex .flex-container .img-sec {
  max-width: 84px;
}

.dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards .propel-flex .flex-container .img-sec img {
  width: 100%;
}

.dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards .propel-flex .flex-container>p {
  font-size: 12px;
  line-height: 16px;
  padding-left: 4px;
}

.dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards .propel-flex>p {
  text-align: left;
  font-size: 11.5px;
  line-height: 12px;
  margin: 0;
  max-width: 165px;
}

.dosing-page #maincontent .dosing-callouts .box.box-2>.box-content>p:last-child {
  font-size: 11px;
  line-height: 14px;
  padding: 8px 0 7px;
}

.dosing .propel-update-section-4 .green-flex .box {
  background-color: #E8F1CF80;
}

.dosing #maincontent .dose-modification-content p {
  max-width: 914px;
  font-size: 14px;
  line-height: 15px;
  color: #525252 !important;
}

.dosing #maincontent .dose-modification-content {
  margin-bottom: 20px;
}

.dosing #maincontent .section-2.dosing .combination .part-two .box-new-2 p a {
  color: #525252;
}

.dosing #maincontent .dosing-ul-eff {
  padding-left: 0px;
  list-style: none;
}

.dosing #maincontent .dosing-ul-eff li {
  padding-left: 6px;
  position: relative;
}

.dosing #maincontent .dosing-ul-eff li::before {
  content: '';
  position: absolute;
  left: 0px;
  top: 4px;
  width: 3px;
  height: 3px;
  background-color: #525252;
  border-radius: 50%;
}

/* Dosing ends */
/* PMLR -4 Updated */
.section-3.flex-box .card .card-content>p.newly-added-header {
  /* text-align: center;
    margin-right: 21px; */
  margin-left: 108px;
  position: relative;
  font-size: 20px;
  line-height: 24px;
  top: 3px;
}


@media screen and (min-width:1004px) and (max-width:1300px) {
  .home-combination .combination-container .section-1 {
    max-width: 570px;
    padding-top: 37px;
  }

  .home-combination .combination-container,
  .home-mono .home-mono-container,
  .home.prostate-home .nccn-section {
    padding: 0 30px;
  }

  .section-3.flex-box {
    gap: 15px;
    margin-top: -4px;
  }

  .parpi-section .flex-box.parpi-img-section {
    gap: 20px;
  }

  .combination-container .comb-ref-links {
    max-width: 425px;
  }

  .combination-container .comb-ref-links .comb-links li a {
    font-size: 9px;
    margin-right: -2px;
  }

  .combination-container .comb-ref-links>p {
    font-size: 9px;
  }

  .combination-container .comb-ref-links .comb-links {
    padding: 5px 0;
    gap: 19px;
  }

  .patient-profiles .tab-head-container.propel-update-q1 .tabs-body,
  .patient-profiles .combination-therapy,
  .patient-profiles .mono-patient-profile .monotherapy {
    padding: 0 30px;
  }

  body.prostrate_efficacy.monotherapy .max-width {
    padding-left: 30px;
    padding-right: 30px;
  }

  .flex-box.section-2 .flag-image img {
    max-width: 330px;
    margin-bottom: 2px;
  }

  .flex-box.section-2 {

    margin: 20px 0 7px;
  }

}

@media screen and (min-width : 1004px) {
  .section-3.flex-box .card {
    border: 1px solid #004D74;
  }

  .patient-profiles .monotherapy .visible-hidden {
    visibility: hidden;
  }

  .patient-profiles .cta-button.mobile-view-only {
    display: none;
  }

  .dosing #maincontent .propel-update-dosing-comb .box-2 .flex-box.precaution .with-precaution img {
    max-width: 53px;
  }

  .dosing #maincontent .propel-update-dosing-comb .mobile-view-only {
    display: none;
  }

  .dosing .combination.therapy {
    margin: 12px 0;
  }

  .dosing #maincontent .propel-update-dosing-comb .single-dosage .capsule-box {
    max-width: 180px;
    width: 100%;
  }

  .dosing #maincontent .propel-update-dosing-comb .card-footnote.tab-desc p {
    padding-left: 15px;
    padding-top: 5px;
  }

  .dosing .propel-update-dosing-comb .combination {
    margin-bottom: 0;
  }

  .dosing .propel-update-section-4 .green-flex .box-1 .box-content .img-sec {
    overflow: hidden;
    text-align: center;
    display: flex;
    justify-content: center;
    max-width: 148px;
  }

  .patient-profiles .combination-therapy .box-2 .patient-details-list:last-child ul {
    margin-bottom: 0;
  }

  .flex-box.section-2 .box-2 {
    display: flex;
    align-items: center;
    flex-direction: column-reverse;
  }

  .flex-box.section-2 .box-2>img {
    max-width: 33px;
  }

  body.prostrate_efficacy .propel-examined a.flex-container {
    padding: 15px 20px !important;
  }

  .combination-therapy .section-2 .propel-content .sec71bg {
    padding-right: 20px !important;
  }

  .dosing #maincontent .dosing-ul-eff li {
    padding-left: 6.5px;

  }

  /* dsoing li update */
  .dosing .section-3 .section-2.dosing .combination .part-two .box-1>.lynparza {

    gap: 20px;
  }

  .dosing .section-3 .section-2.dosing .combination .part-two .box-1>.lynparza>.flex-box {
    gap: 8px;
  }

  .dosing #maincontent .section-3 .section-2.dosing .flex-box.main-flex .box-1 .capsule-box {

    gap: 7px;
  }

  .section-2.dosing .combination .part-two .box-new-2 {
    max-width: 428px;
  }

  /* dsoing li update */

  /* PMLR 3 updates */
  .dosing .section-3 .propel-update-dosing-comb .combination {
    margin-top: 19px;
  }

  .dosing .section-3 .propel-update-dosing-comb .combination .section-heading {
    margin-bottom: 6px;

  }

  .dosing #maincontent .section-3 .propel-update-dosing-comb .flex-box.part-two {
    align-items: flex-start;
    flex-basis: 160px;
    min-height: 160px;
  }

  .dosing #maincontent .section-3 .section-2.dosing .combination .section-container {
    display: flex;
    flex-direction: column;
  }

  .dosing #maincontent .section-3 .section-2.dosing .combination .part-two .box-1 {
    padding: 3px 0 38px 31px;
    max-width: 576px;

  }

  .dosing #maincontent .section-3 .propel-update-dosing-comb .card-side-head {
    line-height: 17px;
  }

  #maincontent .section-2.dosing .combination .part-two .box-new-2 .section-content .contnet-heading {
    margin-bottom: 9px;
  }

  .dosing #maincontent .section-3 .propel-update-dosing-comb .card-footnote.tab-desc p {
    padding-top: 3px;
  }

  .dosing #maincontent .section-3 .propel-update-dosing-comb .main-heading {
    line-height: 26px;
  }

  .dosing #maincontent .section-3 .propel-update-dosing-comb .card-side-head {
    letter-spacing: -0.32px;
  }

  /* PMLR 3 Updates */
}




@media screen and (max-width:1003px) {
  body.prostrate_efficacy .section-4 .propel-content .Primary_endpoint .content p {
    font-size: 12px;
  }

  body.prostrate_efficacy .section-4 .propel-content .Primary_endpoint .content {
    margin-top: 32px !important;
  }

  /* ************************************************** */
  .efficacy-mono.section-8.lt-grey-bg.pros-update-study-design .img-sec img {
    max-width: 375px;
    width: unset;
  }

  .efficacy-mono.section-8.lt-grey-bg.pros-update-study-design .img-sec {
    margin: 5px 0 15px -19px;
  }

  .moa.mechanism-of-action.global-redesign.pr-tumor-type main#maincontent {
    margin-top: 160px !important;
  }

  .efficacy-mono.section-8 .mob-new-content {
    font-size: 20px !important;
    line-height: 24px;
    margin: 0;
  }

  section.efficacy-mono-profound p:nth-child(4) {
    margin-top: 10px;
  }

  .section-3.flex-box .card,
  .combination-container .comb-ref-links,
  .home-mono .home-mono-container .mono-content,
  .home-mono .mono-card,
  .parpi-section .flex-box.parpi-img-section>* {
    max-width: 100% !important;
  }

  .home-mono .home-mono-container .mono-content {
    width: 100%;
  }

  .section-2.dosing .combination .box {
    max-width: 100%;
  }

  body.prostrate_efficacy .section-4 .efficacy-graph-container .graph-head .pink-bg.skew-10 h2 {
    padding-right: 10px !important;
  }

  .dosing-page #maincontent .dose-modification>div:last-child>p {
    padding-right: 10px;
  }

  .dose-modification table tr:first-child td:last-child {
    padding-left: 5px;
    padding-right: 5px;
  }

  /* ************************************************** */
  .propel-home-banner .home-mono {
    border-top: 12px solid #004D74 !important;
  }

  .home-mono .home-mono-container .mono-image {
    display: none;
  }

  .section-3.flex-box {
    flex-direction: column;
    padding: 0;
  }

  .home-combination .combination-container .section-1 {
    padding: 20px 31px 0 17px;
  }

  .home-combination .combination-container .section-1 .section-subhead {
    margin: 0;
  }

  .home-combination .combination-container .section-1 .section-heading {
    font-size: 22px;
    line-height: 27px;
    max-width: 172px;
    margin: 10px 10px 0 auto;
  }

  .propel-home-banner .home-combination .not-actual-text {
    max-width: 172px;
    margin: 32px 20px 0;
    position: relative;
    z-index: 2;
  }

  .flex-box.section-2>* {
    padding: 0 32px 0 20px;
  }

  .home-eyebrow-head p>span {
    font-size: 14px;
    line-height: 18px;
    letter-spacing: 1.5px;
    padding: 7px;
  }

  .flex-box.section-2 {
    flex-direction: column-reverse;
    gap: 10px;
    max-width: calc(100% - 20px);
  }

  .flex-box.section-2 {
    /* flex-direction: column; */
    align-items: flex-start;
    margin: 6px 0 0;
  }

  .home-combination {
    background-image: none;
  }

  .home-eyebrow-subhead {
    font-size: 16px;
    line-height: 19px;
  }

  .section-2 .home-eyebrow-subhead {
    margin: 10px 0 14px;
  }

  .flex-box.section-2 .box-2 {
    max-width: 100%;
    text-align: left;
    display: flex;
    flex-direction: row-reverse;
    gap: 20px;
    align-items: center;
    background-color: #990064;
    padding-top: 2px;
    padding-bottom: 5px;
    margin-left: 20px;
  }

  .flex-box.section-2 .box-2 p {
    margin: 0;
  }

  .section-3.flex-box .card {
    padding: 12px 25px 21px 14px;
  }

  .section-3.flex-box .card .card-content .flex-content .content p {
    letter-spacing: -0.48px;
  }

  .section-3.flex-box .card .card-content .flex-content .content .subhead {
    letter-spacing: -1.2px;
  }

  .section-3.flex-box .card .card-content .flex-content .content .data {
    padding: 0;
  }

  .section-3.flex-box .card-link {
    text-align: center;
  }

  .section-3.flex-box .card.card-1 {
    border-bottom: 6px solid #990064;
  }

  .section-3.flex-box .card.card-2 .card-content .flex-content .content .data {
    padding: 0;
    letter-spacing: -0.8px;
  }

  .combination-container .comb-ref-links {
    margin: 0;
    padding: 0 34px 0 20px;
    background-color: #F5E6F0;
  }

  .section-3.flex-box .card.card-2 {
    padding-bottom: 10px;
  }

  .combination-container .comb-ref-links .comb-links {
    flex-direction: column;
    gap: 8px;
    justify-content: center;
    align-items: center;
    padding: 14px 0 22px;
  }

  .home-mono .home-mono-container .mono-inner-section {
    padding: 22px 20px 28px 19px;
  }

  .propel-home-banner {
    background: none;
  }

  .home-mono .mono-card {
    border: none;
    background-color: transparent;
    padding: 0;
  }

  .home-mono .mono-card>.home-eyebrow-subhead {
    font-size: 20px;
    line-height: 24px;
    margin-top: 10px;
  }

  .home-mono .mono-card .card-link>a {
    background-color: white;
  }

  .mono-inner-section {
    background-color: #F3E8EE;
  }

  .home-mono .home-mono-container .mono-content {
    padding: 0;
  }

  .home-mono-container .mono-content .home-eyebrow-subhead.mono-section-head {
    margin: 12px 0;
  }

  .home-mono .pros-footnote {
    padding: 12px 34px 20px 20px;
  }

  .combination-container .mob-bg-gradient {
    background: transparent linear-gradient(174deg, #990064 0%, #99006400 300%);
    position: relative;
  }

  img.home-combination-banner {
    position: absolute;
    bottom: 0;
    /* bottom: 22.2px; */
    max-width: 301px;
    left: 0px;
    z-index: 0;
  }

  .home-combination .combination-container .section-1,
  .flex-box.section-2 {
    position: relative;
    z-index: 1;
  }

  .propel-home-banner .home-mono {
    border-bottom: none;
  }

  .flag-image img {
    max-width: 300px;
    margin-bottom: 0;
  }

  .home.prostate-home .nccn-section .nccn-container {
    margin: 0;
    padding: 12px 18px 29px 18px;
  }

  .home.prostate-home .nccn-section .nccn-container>p:first-child {
    font-size: 32px;
    line-height: 38px;
  }

  .home.prostate-home .nccn-section .nccn-container>p:nth-child(2) {
    margin: 12px 0;
    padding-right: 10px;
  }

  .home.prostate-home .nccn-section .nccn-container .flex-box {
    flex-direction: column;
    gap: 24px;
  }

  .home.prostate-home .nccn-section .nccn-container .flex-box p.card-link {
    margin: 0;
    text-align: center;
    width: 100%;
    max-width: 100%;
  }

  .home.prostate-home .nccn-section .nccn-container .flex-box .pros-footnote {
    margin: 0;
    padding-right: 18px;
  }

  .parpi-section .flex-box.parpi-img-section {
    flex-direction: column;
    gap: 12px;
  }

  .home .parpi-section {
    padding: 18px 20px 0;
  }

  .home .parpi-section .pros-footnote {
    padding-right: 20px;
  }

  .home-mono .home-mono-container {
    margin-top: 0;
  }

  .home-mono .flag-image img {
    margin-top: 0;
    max-width: 270px;
  }

  /* Patient care page starts */

  .patient-profiles .tab-head-container.propel-update-q1 {
    padding: 20px 0 0;
    height: auto !important;
    max-width: 100% !important;
    width: 100%;
  }

  .patient-profiles .tab-head-container.propel-update-q1 .tab-heading h1 {
    font-size: 30px;
    line-height: 40px;
    padding: 18px 34px 22px 20px;
    max-width: 100% !important;
  }


  .patient-profiles .propel-update-q1 #tab-opener-1>a,
  .patient-profiles .propel-update-q1 #tab-opener-2>a {
    font-size: 15px;
    line-height: 18px;
  }

  .patient-profiles .propel-update-q1 #tab-opener-1>a {
    padding: 10px 11px 15px !important;
  }

  .patient-profiles .propel-update-q1 #tab-opener-2>a {
    padding: 10px 29px 15px;
    margin: 0;
  }

  .patient-profiles .propel-update-q1 .tab-links .link-parent {
    background-color: white;
  }

  .patient-profiles .propel-update-q1 .tab-links .link-parent#tab-opener-2 {
    background-color: #F3E8EE;
  }

  .patient-profiles .flex-box.patient {
    flex-direction: column;
    /* padding: 0 20px; */
  }

  .patient-profiles .patient-details-list ul li:before {
    left: 1px;
  }

  .patient-profiles .section-head p {
    padding: 12px 22px 24px;
  }

  .patient-profiles .patient-heading {
    font-size: 22px;
    line-height: 38px;
  }

  .patient-profiles .combination-therapy .flex-box.patient .box-2 {
    padding-top: 0;
    padding-right: 15px;
  }

  .patient-profiles .skew-desc {
    transform: none;
    margin: 6px 0 34px;
  }

  .patient-profiles .skew-desc p {
    transform: none;
  }

  .patient-profiles .flex-box.patient .box>* {
    padding-left: 20px;
    padding-right: 20px;
  }

  .patient-profiles .monotherapy .patient-details-list:has(.pink-ball) {
    padding-left: 53px;
    padding-right: 34px;
  }

  .patient-profiles .patient-details-list ul li ul.patient-details-sublist {
    padding-left: 17px;
  }

  .patient-profiles .cta-button.desktop-view-only {
    display: none;
  }

  .patient-profiles .flex-box.patient .cta-button.mobile-view-only {
    margin-bottom: 40px;
  }

  .patient-profiles .monotherapy .visible-hidden {
    display: none;
  }

  /* Patient care page ends */
  .deskop-inline-block {
    display: none;
  }

  .mobile-inline-block {
    display: inline-block;
  }

  .dosing #maincontent .propel-update-dosing-comb .flex-box.main-flex {
    flex-direction: column;
    gap: 20px;
  }

  .section-2.dosing .combination .box-1,
  .section-2.dosing .combination .box-1 .lynparza,
  .section-2.dosing .combination .box-2,
  .section-2.dosing .combination .box-2 .abiraterone-new,
  .section-2.dosing .combination .part-two .box-1 {
    transform: none;
    margin: 0;
    left: unset;
    right: unset;
  }

  .section-3 .propel-content .Primary_endpoint.section-71 .skew-maroon-head h2 {
    padding-left: 15px;
  }

  body.prostrate_efficacy.combination-therapy .section-3 .propel-content.cont-4 .Primary_endpoint .skew-maroon-head.sec71bg.sec71bg1 {
    margin-left: -36px !important;
    padding-top: 15px;
    padding-left: 22px;
  }

  .combination-therapy .section-2 .skew-maroon-head.sec71bg.sec71bg1 {
    margin-bottom: 8px;
  }

  .section-2.dosing .combination .box-1 {
    padding: 13px 20px 30px 10px;
  }

  .dosing #maincontent .propel-update-dosing-comb .card-side-head+.flex-box {
    flex-direction: column;
    gap: 15px;
    margin-top: 10px;
  }

  .section-2.dosing .combination .box-2 {
    padding: 32px 20px 19px 10px;
  }

  .dosing .therapy .section-heading {
    margin-bottom: 14px;
  }

  .dosing #maincontent .propel-update-dosing-comb .flex-box.new-update-propel {
    flex-direction: column;
  }

  .dosing #maincontent .propel-update-dosing-comb .flex-box-new>.flex-box {
    flex-direction: column;
  }

  .dosing #maincontent .propel-update-dosing-comb .box-2 .capsule-box .capusles {
    flex-direction: column;
  }

  .dosing #maincontent .propel-update-dosing-comb .flex-box-new>.flex-box .mobile-flex {
    display: flex;
    gap: 20px;
    margin: 6px 0 10px;
  }

  .dosing #maincontent .propel-update-dosing-comb .desktop-view-only {
    display: none;
  }

  .dosing #maincontent .propel-update-dosing-comb .card-normal-text {
    letter-spacing: -0.38px;
    margin-bottom: 5px;
  }

  .dosing #maincontent .combination .section-container p.devider-line:before,
  .dosing #maincontent .combination .section-container p.devider-line:after {
    max-width: 71px;
  }

  .dosing #maincontent .combination .section-container p.devider-line {
    justify-content: center;
    font-style: italic;
    font-family: 'myriad-pro', sans-serif !important;
    font-weight: bold;
    margin: 15px 0 20px;
  }

  .dosing #maincontent .propel-update-dosing-comb .flex-box.single-dosage {
    flex-direction: column;
  }

  .dosing #maincontent .propel-update-dosing-comb .flex-box.single-dosage .flex-box.capsule-box {
    align-items: flex-end;
  }

  .section-2.dosing .combination .box-2:before {
    left: 50%;
    top: -10px;
    transform: skewX(0) translate(-50%, -50%);
  }

  .section-2.dosing .combination .part-two .box-1>.lynparza {
    flex-direction: column;
    align-items: flex-start;
  }

  .section-2.dosing .combination .part-two .box-1 {
    padding: 13px 21px 10px 10px;
  }

  .section-2.dosing .combination .part-two .box-1>.lynparza>.flex-box {
    flex-direction: column;
    gap: 10px;
    margin-top: 15px;
  }

  .section-2.dosing .combination .part-two .box-1>.lynparza .flex-box-2 {
    max-width: 100%;
  }

  .section-2.dosing .combination .part-two .box-new-2 {
    margin: 0;
    max-width: 100%;
    padding-right: 18px;
  }

  .dosing #maincontent .propel-update-dosing-comb .card-footnote p.mobile-view-only {
    margin: 10px 0;
  }

  .dosing .propel-update-section-4 .green-flex {
    margin: 0;
    gap: 48px;
  }

  .dosing .section-4.propel-update-section-4 {
    padding: 0 20px;
  }

  .dosing .propel-update-section-4 .green-flex .box .box-content {
    background: #E8F1CF80;
  }

  .dosing .propel-update-section-4 .green-flex .box {
    background: transparent;
    max-width: 100%;
  }

  .dosing .propel-update-section-4 .green-flex .box-1:after {
    top: unset;
    bottom: -10px;
    left: 50%;
    right: unset;
    position: absolute;
    transform: skewX(-10deg) translate(-50%, 100%);
    padding: 0.5px 4px;
  }

  .dosing #maincontent .propel-update-section-4 .green-flex .box .box-heading p {
    font-size: 19px;
    line-height: 30px;
    padding: 5.5px;
  }

  .dosing .propel-update-section-4 .green-flex .box-2 {
    margin: 0 0 10px;
  }

  .dosing #maincontent .propel-update-section-4 .dosing-callouts .green-flex .box-1 p.box-subhead {
    max-width: 190px;
    margin: 0 auto;
  }

  .dosing-page #maincontent .dosing-callouts .box.box-2>.box-content>.flex-container.skew-flex {
    margin: 10px 0 0;
    gap: 28px;
    justify-content: center;
    align-items: center;
  }

  .dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards {
    max-width: 82%;
    padding: 8px 10px 8px 0;
    margin-left: -10px;
  }

  .dosing .propel-update-section-4 .green-flex .box-1 .box-content .img-sec {
    padding-top: 10px;
  }

  .dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards .propel-flex {
    flex-direction: column;
    align-items: center;
    gap: 8px;
  }

  .dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards .propel-flex .flex-container {
    flex-direction: row;
    align-items: center;
    gap: 15px;
  }

  .dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards .propel-flex .flex-container>p {
    padding: 0;
  }

  .dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards .propel-flex>p {
    text-align: center;
    max-width: 100%;
  }

  .dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards.card-1 .propel-flex>p {
    padding: 0 20px;
  }

  .patient-profiles .tab-heading {
    order: 1;
    max-width: 100%;
  }

  .patient-profiles .propel-update-q1 .tab-links>nav>.nav-tabs {
    justify-content: center;
  }

  .patient-profiles .tab-head-container.propel-update-q1 .tabs-body {
    align-items: center;
  }

  .moa.mechanism-of-action .moa-combi.container-center .img_sec img.mobile {
    max-width: 100%;
  }

  .moa.mechanism-of-action .img-cont {

    text-align: center;
  }

  .moa.mechanism-of-action .img-cont img {
    width: 100%;
  }

  .nccn-guidelines.lynhcp-pro-integrate .card-content {
    padding: 0px 24px 0px 8px;
  }

  /*  dosing li update */
  .dosing #maincontent .dosing-ul-eff {
    padding-left: 0px;
  }

  .section-2.dosing .combination .part-two .box-new-2 {
    padding-left: 2px;
    padding-right: 8px;
  }

  .section-3.flex-box .card .card-content>p.newly-added-header {
    /* text-align: center;
    margin-right: 21px; */
    margin-left: 103px;

  }
}

@media screen and (min-width: 376px) and (max-width: 1003px) {
  .efficacy-mono.section-8.lt-grey-bg.pros-update-study-design .img-sec img {
    max-width: 100%;
    width: 100%;
  }

  body.combination-therapy #propel-p3 .chart-image img {
    margin: 0 auto;
    width: 100%;
  }

  body.prostrate_efficacy .efficacy-graph-container .img_sec img {
    /* max-width: 334px; */
    margin: 0 auto;
    width: 100%;
    max-width: 100% !important;
    padding: 0 18px;
  }
}

@media screen and (min-width:480px) and (max-width:483px) {
  p.image-after {
    padding-right: 30px;
  }
}

@media screen and (max-width: 352px) and (min-width: 348px) {
  .az-logo a {
    margin-right: -10px;
  }
}

@media screen and (min-width:398px) and (max-width: 1003px) {


  .dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards {

    padding: 8px 13px 8px 0;
  }

  .dosing-page #maincontent .dosing-callouts .box.box-2>.box-content>p:first-child {

    padding: 0 10px;
  }
}

@media screen and (min-width:400px) and (max-width: 1003px) {

  .patient-profiles .flex-box.patient .box,
  .patient-profiles .patient-image img,
  .patient-profiles .combination-therapy .flex-box.patient .box-2,
  .patient-profiles .skew-desc {
    max-width: 100%;
  }
   .home-combination .combination-container .section-1 {
    min-height: 350px;
    margin-left: 0;
    max-width: 100%;
  }
      .section-3.flex-box .card .card-content>p.newly-added-header {
        margin-left: 108px;
    }
}

@media screen and (min-width:1004px) and (max-width:1060px) {
  .section-2.dosing .combination .part-two .box-1 {
    padding-right: 10px;
  }

  .dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards {
    max-width: 290px;
  }
}

@media screen and (min-width: 500px) and (max-width:1003px) {

  .home-combination .combination-container .section-1 .section-heading,
  .propel-home-banner .home-combination .not-actual-text {
    max-width: 100%;
    margin-left: 240px;
  }

  /* .home-combination .combination-container .section-1 {
    min-height: 350px;
    margin-left: 0;
    max-width: 100%;
  } */

  img.home-combination-banner {
    bottom: 0;
  }

  .flex-box.section-2 .box-2 {
    justify-content: flex-end;
  }

  body.prostrate_efficacy .propel-examined>p {
    max-width: 100% !important;
  }

  .combination-therapy .section-2 .skew-maroon-head.sec71bg.sec71bg1 {
    margin-left: -20px;
    margin-top: 20px;
  }

  body.prostrate_efficacy.combination-therapy .section-3 .propel-content.cont-4 .Primary_endpoint .skew-maroon-head.sec71bg.sec71bg1 {
    margin-left: -60px !important;
    padding-left: 50px;
  }

  .resource-library #maincontent .container-center {
    width: 100% !important;
  }

  /*.resource-library .tab-head-container.tab-head-left.tab-head-left1 {
    margin: 25px auto !important;
    width: 93% !important;
  } */

  body.resource-library.video-library.ps3-video.lynhcp-pro-integrate .patient-res.resources-padding-lt .row {
    margin: 10px 0 0;
  }

  body.resource-library.video-library.ps3-video.lynhcp-pro-integrate .patient-res.resources-padding-lt {
    padding: 10px 0 5px !important;
  }

  .resource-library.video-library.ps3-video.lynhcp-pro-integrate .double-pan-column {
    padding: 0 !important;
  }

  .resource-library.video-library.ps3-video.lynhcp-pro-integrate .double-pan-column .pancreatic-column.patient-column {
    border-left: none;
    border-right: none;
  }

  body.resource-library.video-library.ps3-video.lynhcp-pro-integrate .patient-res.resources-padding-lt h2 {
    padding: 0 20px;
  }

  .resource-library.video-library.ps3-video.lynhcp-pro-integrate .box.box-1.flex-container .box-image {
    max-width: 115px;
    width: 100%;
  }

  .resource-library.video-library.ps3-video.lynhcp-pro-integrate .box.box-1.flex-container .box-image img {
    width: 100%;
  }

  .lynhcp-pro-integrate.video-library #videos>div.grid:first-child>div .col-xs-12.col-sm-8 {
    max-width: 100%;
  }

}

@media screen and (Min-width:768px) and (max-width:1003px) {
  .resource-library .tab-head-container.tab-head-left.tab-head-left1 {
    margin-left: auto !important;
    width: 90%;
    margin-right: auto !important;
  }
}

@media screen and (min-width: 767px) and (max-width: 819px) {
  .video-library .tab-links {
    width: unset !important;
  }

  .resource-library .tab-head-container.tab-head-left.tab-head-left1 {
    padding-bottom: 12px;
  }
}

@media screen and (max-width : 370px) {
  .home-combination .combination-container .section-1 {
    padding-right: 15px;
  }

  img.home-combination-banner {
    max-width: 240px;
  }

  .section-2 .home-eyebrow-subhead {
    font-size: 14px;
  }

  .flag-image img {
    max-width: 250px;
  }

  .efficacy-mono.section-8.lt-grey-bg.pros-update-study-design .img-sec img {
    width: 100%;
  }

  .efficacy-mono.section-8.lt-grey-bg.pros-update-study-design .img-sec {
    margin-right: -14px;
  }

  .combination-therapy.safety-tolerability.safety-combination-theraphy.pc3-combi.lynhcp-pro-integrate.global-redesign.pr-tumor-type .cta-button a {
    font-size: 16px;
  }

  .patient-profiles .cta-button a {
    /* padding-left: 20px; */
    /* padding-right: 20px; */
    max-width: 85%;
  }

  .home .propel-home-banner .home-combination .not-actual-text {
    margin-top: 0;
  }

  .home .flex-box.section-2 .box-2 p {
    font-size: 12px;
  }

  .home .section-2 .home-eyebrow-subhead {
    font-size: 11px;
  }

  .dosing #maincontent .propel-update-section-4 .dosing-callouts .box.box-2>.box-content>.flex-container .cards {

    padding: 8px 12px 8px 0;

  }

  .patient-profiles .cta-button a span {
    font-size: 16px;
  }
}


/*************************/

@media screen and (min-width: 400px) and (max-width:1100px) {


  .combination-therapy.safety-tolerability.safety-combination-theraphy.pc3-combi.lynhcp-pro-integrate.global-redesign.pr-tumor-type .footnotecontiner p.footnote,
  .monotherapy.profound.safety-tolerability .footnotecontiner p.footnote {
    padding-left: 0;
  }



  .safety-combination-theraphy .clinicalstudytxt:first-child,
  .monotherapy.profound.safety-tolerability .clinicalstudytxt:first-child,
  .neww-table.safety-olympia-table.sp1-table1,
  .monotherapy.profound.safety-tolerability .neww-table.safety-olympia-table.sp1-table1,
  .combination-therapy.safety-tolerability.safety-combination-theraphy.pc3-combi.lynhcp-pro-integrate.global-redesign.pr-tumor-type .section-one .safetylistsect,
  .monotherapy.profound.safety-tolerability .section-one .safetylistsect,
  .combination-therapy.safety-tolerability.safety-combination-theraphy.pc3-combi.lynhcp-pro-integrate.global-redesign.pr-tumor-type .footnotecontiner.container-center,
  .monotherapy.profound.safety-tolerability .footnotecontiner.container-center {

    padding-right: 20px !important;
    padding-left: 20px !important;
  }

  .safety-tolerability .section-two,
  .monotherapy.profound.safety-tolerability .section-two {
    padding: 0 !important;
  }

  .neww-table {
    width: 100%;
  }

  .safety-tolerability .section-two .footnotecontiner {
    max-width: 1003px;
  }
}

@media screen and (min-width: 1004px) and (max-width:1300px) {
  .home-combination {
    padding-top: 50px;
  }


}

@media screen and (min-width: 1004px) and (max-width:1100px) {

  .combination-therapy.safety-tolerability.safety-combination-theraphy.pc3-combi.lynhcp-pro-integrate.global-redesign.pr-tumor-type .section-one .footnotecontiner.container-center,
  .monotherapy.profound.safety-tolerability .section-one .footnotecontiner.container-center {

    padding-left: 28px !important;
  }

  .safety-combination-theraphy .clinicalstudytxt:first-child,
  .monotherapy.profound.safety-tolerability .clinicalstudytxt:first-child {
    padding-left: 30px !important;
  }

  .monotherapy.profound.safety-tolerability .propel-content .container-center,
  .combination-therapy.safety-tolerability .propel-content .container-center {
    padding-right: 45px;
  }

  .resource-library .patient-res.resources-padding-lt {
    padding: 10px 0 5px !important;
    margin: 0;
  }

  .resource-library.video-library.ps3-video.lynhcp-pro-integrate .patient-res .pancreatic-column {
    width: auto !important;
  }

  .resource-library.video-library.ps3-video.lynhcp-pro-integrate .double-pan-column:nth-child(2) .pancreatic-column.patient-column {
    margin: 0;
  }

  .resource-library.video-library.ps3-video.lynhcp-pro-integrate .double-pan-column {
    flex-basis: 50%;
  }

  .patient-res.resources-padding-lt .row {
    display: flex;
    flex-wrap: wrap;
  }

  .resource-library.video-library.ps3-video.lynhcp-pro-integrate div#videos.tab-pane.active.in>.grid.section>.clearfix {
    width: auto !important;
  }

  .resource-library .video-callouts {
    padding: 0;
  }

  .lynhcp-pro-integrate.video-library #videos>div.grid:first-child>div .col-xs-12.col-sm-8 {
    padding-left: 0;
  }

  .lynhcp-pro-integrate.video-library #videos>div.grid:first-child>div.pr-video-update .col-xs-12.col-sm-4>div .desc {
    padding: 0 !important;
  }

  .pros-update-safety.hrrm-testing .section-one .page-heading,
  .pros-update-safety.hrrm-testing .section-2 .section-2-content,
  .pros-update-safety.hrrm-testing.testing.section-3.grey-bg,
  .pros-update-safety.hrrm-testing.testing .section-4.testing,
  .pros-update-safety.hrrm-testing.testing .section-5 {
    margin-left: 0;
    margin-right: 0;
  }

  .pros-update-safety .testing.section-3 .pie-chart-container>.flex-container>.box-2 {
    margin-left: 10px;
  }

  .pros-update-safety .testing.section-3 .pie-chart-container>.flex-container .card {

    margin-bottom: 10px;
  }

  .dosing #maincontent .section-3 .section-2.dosing .flex-box.main-flex .box-1 .capsule-box {
    gap: 5px;
  }

  .dosing .section-3 .section-2.dosing .combination .part-two .box-1>.lynparza>.flex-box {
    gap: 7px;
  }

  .dosing .section-3 .section-2.dosing .combination .part-two .box-1>.lynparza {
    gap: 8px;
  }

  .dosing #maincontent .section-3 .section-2.dosing .combination .part-two .box-1 {
    padding: 3px 0 38px 28px;
  }

  .combination-therapy .safetylistsect ul {
    margin-left: -2.4%;
  }

  .monotherapy .safetylistsect ul {
    margin-left: -3.4%;
  }

  body.monotherapy.profound.safety-tolerability .footnotecontiner.container-center.graycolortxt.ipadp-pLeft20 p {
    padding-left: 5px !important;
  }
}

@media screen and (min-width: 1024px) and (max-width:1060px) {
  .dosing #maincontent .section-3 .section-2.dosing .flex-box.main-flex .box-1 .capsule-box {
    gap: 4px;
  }

  .dosing .section-3 .section-2.dosing .combination .part-two .box-1>.lynparza>.flex-box {
    gap: 7px;
  }

  .dosing .section-3 .section-2.dosing .combination .part-two .box-1>.lynparza {
    gap: 4px;
  }

  .dosing #maincontent .section-3 .section-2.dosing .combination .part-two .box-1 {
    padding: 3px 0 38px 27px;
  }
}

@media screen and (min-width: 1020px) and (max-width:1033px) {
  .dosing #maincontent .section-3 .section-2.dosing .combination .part-two .box-1 {
    /* padding: 3px 0 38px 31px; */
    max-width: 530px;
  }
}

@media screen and (min-width: 400px) and (max-width:600px) {

  .safety-combination-theraphy .safetylistsect ul,
  .monotherapy.profound.safety-tolerability .safetylistsect ul {
    padding-left: 2px !important;
    margin-left: 0px;
  }
}

@media screen and (min-width: 992px) and (max-width: 1003px) {
  .combination-therapy.prostrate_efficacy .reference {
    padding: 0 20px;
  }

}


@media only screen and (min-width: 768px) and (max-width: 1003px) {
  #header .search-box>.search form {
    width: 100%;
  }

  .resource-library .video-frame img {
    width: 100%;
    height: auto;
  }

  .lynhcp-pro-integrate.video-library #videos>div.grid:first-child>div .col-xs-12.col-sm-4 {
    align-content: center;
  }

  .resource-library #maincontent .container-center {
    padding-top: 0;
  }

  .lynhcp-pro-integrate.video-library #videos>div.grid:first-child>div .col-xs-12.col-sm-8 {
    padding-left: 0;
  }

  .resource-library #maincontent .container-center {
    padding-left: 0;
  }

  .resource-library .grid.section {
    margin-left: 30px;
    margin-right: 30px;
  }
}

@media screen and (min-width:1004px) and (max-width:1023px) {
  .prostate-home .footer-parsys .oc-home-footnote {
    padding: 0 20px;
  }

  .video-library .tab-head-container {
    padding: 10px 28px 8px !important;
  }

}

    @media screen and (width:375px){
.span-wrap{white-space: nowrap;}
    }