@font-face {
    font-family: 'MyriadPro-Bold';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/myriadpro-bold.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/myriadpro-bold.otf?#iefix') format('embedded-opentype'), url('/etc/designs/code/physician-services/US/fasenrahcp-unbranded/fonts/myriadpro-bold.woff2') format('woff2'), url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/myriadpro-bold.woff') format('woff'), url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/myriadpro-bold.ttf') format('truetype');
}

@font-face {
    font-family: 'MyriadPro-italics';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/myriadpro-regular.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/myriadpro-regular.otf?#iefix') format('embedded-opentype'), url('/etc/designs/code/physician-services/US/fasenrahcp-unbranded/fonts/myriadpro-regular.woff2') format('woff2'), url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/myriadpro-regular.woff') format('woff'), url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/myriadpro-regular.ttf') format('truetype');
}

/* Temp fix*/
/*.isi-tray{ display: none !important;}*/
/* Temp fix ends */

.scroll-disable{
    overflow: hidden;
}


.home .landing-hero-image {
    background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/desktop/prostrate-desktop-hero-image.jpg);
    background-repeat: no-repeat;
    background-position: center;
        background-position-x: left !important;
    background-size: cover;
    position: relative;
    height: calc(100vw * 0.32);
    /* height: calc(100vw * 0.27);*/
    width: 100%;
    overflow: hidden;
}

.fullnavigation .navbar-default .navbar-nav>li.dose-management {
    right: 233px;
    display: inline-block;
}

.fullheader .list-inline li:nth-child(4) {
    position: absolute;
    top: 44px;
    right: 400px;
    margin-left: 0px;
}

.home .isi-body, .treatment-paradigm .isi-body, .efficacy .isi-body, .hrrm-testing .isi-body{
    padding-bottom: 50px !important;
    }        

.marginbottom20{
margin-bottom:20px;
}            
.margintop0{
margin-top:0px !important;
}      

.margin5{
    margin-top: 5px !important;
    margin-bottom: 5px !important;

}  

.PROfound_wrap .robotbold18txt, .secondary_endpointOS p.robotbold18txt{
font-family: 'Roboto-Bold'!important;
font-size:16px !important;                    
line-height:23px !important;
color:#000 !important;                   
}


.PROfound_wrap .popchartwarp{
	position: relative;
    text-align: center;
	display:none;            
}
.PROfound_wrap .popchartcontent{
	width: 38%;
    position: absolute;
    top: -284px;
    left: 29%;
    background: #f3f7f8;
}

.blocktxt{
display:block;
}

.margin55{
margin-top:55px !important;
    }        

.boldtxt{
font-family: 'Roboto-Bold';
}    
.graytxt{
color:#5E86A0;
}

.astericksymb{
margin-left:-5px;
}


.symboltxt{
position:relative;
top:-2px;            
}        

.hrrm-old .biopsywrap .imgwrap img.bluedroplet {
    float: left;
    width: 63px;
    position: relative;
    left: 20px;
    top: -8px;
}

.hrrm-testing .biopsywrap .basedtxt {
    color: #004D74;
	font-family: 'Roboto-Regular';
    font-size: 16px;          
	margin-top:25px;
	margin-left:38px;                
}


.isi-body ul li::before {
    content: "•";
    font-size: 20px;
    padding-right: 10px;
    top: 3px;
    position: relative;
        margin-left: -15px;
}

.osprofoundtxtTM{
/*margin-top: 24px;
margin-bottom: 26px;*/
margin-top: 40px;
margin-bottom: 26px;
    }


/*hrrm testing new design changes */

.biopsywrap .biopsyheading{
    width: 100%;
    float: left;
    position: relative;
    left: 7px;
	background-color: #004D74;
    transform: skewX(-10deg);
    padding: 1.5% 10px;
    text-align: left;            
}

.biopsywrap .biopsyheading .biocontentshade {
    transform: skewX(+10deg);
    color: #fff;
    font-size: 21px;
    font-family: 'MyriadPro-Bold';
    margin: 0px;
    padding-left: 5px;
    line-height: 32px;
    margin:0 auto;
}

.biopsywrap .biopsyheading .biocontentshade .testtxt {
    font-family: 'MyriadPro-Bold';
    font-size: 21px;
    line-height: 25px;
    margin-top: 0px;
    margin-bottom: 0px;
    color: #fff;
    text-align: left;
    display:inline-block;
    width:3%;
    text-transform:uppercase;
    top: 4px;
    position: relative;
    padding-left: 2px;
}
.biopsywrap .biopsyheading .biocontentshade .mutationstxt {
    font-family: 'MyriadPro-Bold';
    font-size: 21px;
    line-height: 21px;
    margin-top: 0px;
    margin-bottom: 0px;
    color: #fff;
    text-align: left;
    display:inline-block;
    text-transform:uppercase;
     position: relative;
    left: 29%;
    top: 4px;

}

.hrrm-testing .biopsywrap .subheading {
    color: #630C46;
    font-size: 21px;
    font-family: 'Roboto-Bold';
    line-height: 26px;
    margin-top: 8px;
}

.hrrm-testing .biopsywrap .contentwrap {
    display: inline-block;
    width: 100%;
    padding-left: 15px;
}

.hrrm-testing .biopsywrap .contentwrap .italicstxt{
color:#464749;
}                    

.hrrm-testing .biopsywrap .biopsycontent .biosywhitebg{
background-color: #fff;    
} 

.hrrm-testing .biopsywrap .desktop .contentwrap {
    padding-left: 9px;
}

.hrrm-testing .biopsycontent .row {
display:flex;
}                


.margintop20{
margin-top:20px;
}                        

.margintop10{
margin-top:12px;
} 

.margintop50{
margin-top:35px;
} 

.hrrm-testing .biopsywrap .wheretxt{
color:#004D74;
}                                        

.hrrm-testing .biopsywrap .biopsycontent .listcontent{
color:#004D74;
margin-bottom:20px;    
}

.hrrm-testing .biopsywrap .biopsycontent .border-bottom{
border-bottom:1px solid #d4d4d4;
}                                        

.hrrm-testing .biopsywrap .biopsycontent .border-both{
border-left:1px solid #d4d4d4;
border-right:1px solid #d4d4d4;
width: 21%;
}

.hrrm-testing .biopsywrap .contentwrap .logosect img {
    border-bottom: 0px dotted #d4d4d4;
    padding-bottom: 10px;
    margin-bottom: 0px;
}
.hrrm-testing .biopsywrap .contentwrap .logosect {
    border-bottom: 0px solid #d4d4d4;
    padding-bottom: 0px;
    margin-bottom: 0px;
}

.width75{
width:75%;
}        

.width90{
width:96%;
    }   
.width55{
width:59%;
}                

.middlealign{
	display: flex;
    align-self: center;
    }


.desktop-md{
display:inline-block;
    } 

@media (max-width: 1023px){
.fullheader ul.list-inline li span.thissitetxt {
    opacity: 1;
}
.home .landing-hero-image {
		background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/mobile/prostrate-mobile-hero-image.jpg);
		/*height: calc(100vw * 0.65);*/
    	height: calc(100vw * 0.80);
	}
}            

@media (min-width: 992px) and (max-width: 1023px) {
.brca_flex_one .flex_content, .brca_flex_two .flex_content {
    margin-top: 30px; 
}
        .mobile-callout{
display:inline-block !important;
 }  
}



@media (min-width:993px) and (max-width: 1024px){
.desktop-md{
display:inline-block !important;
}  
.mobile{
display:none !important;
}
 .desktop{
display:inline-block !important;
 }   



.biopsywrap .biopsyheading .biocontentshade{
padding-left:20px;
}                
.home-content .recommend h2.subheading {
    position: relative;
    left: 3px;
}
.home-content .recommend .nccntxt {
    margin-left: 3px;
    padding-left: 0px;
}
.home-content .footnote {
    text-indent: 0px;
}

.treatment-paradigm .platinum_chart img, .safety-tolerability .platinum_chart img {
    width: auto;
    max-width: 100%;
}
.hrrm-testing .prognastic .footnote {
    margin-left: 0px;
}
.fullheader .list-inline li:nth-child(4) {
    top: 40px;
}

}

@media (min-width: 992px) and (max-width: 1023px) {
     .mobile-callout{
display:inline-block !important;
 }  
}


@media (min-width: 768px) and (max-width: 1023px) and (orientation: portrait){
.hrrm-testing .flex_content ul {
    margin-left: 0%;
    margin-top: 0px;
}
.hrrm-testing .biopsywrap .basedtxt {
    margin-left: 17px;
}
.ipadnowrap{
white-space: nowrap;
        }

.dosing-page #maincontent {
    margin-top: 141px !important;
}
}

/*ipad landscape styles*/

@media (min-width:992px) and (max-width: 1024px) and (orientation : landscape){

.biopsywrap .biopsyheading .biocontentshade {
    padding-left: 10px;
}        
.hrrm-testing .biopsywrap .contentwrap ul.listcontent li.magenta {
    width: 90%;
}             
.hrrm-testing .biopsywrap .contentwrap .logosect {
    width: 95%;
}
.hrrm-testing .biopsywrap{
width: 100%;
}
.desktop-md{
display:inline-block !important;
    }        
.biopsywrap .biopsyheading .biocontentshade .mutationstxt {
    left: 29.5%;
}

.biopsywrap .biopsycontent .biosywhitebg .col-xs-4, .biopsywrap .biopsycontent .biosywhitebg .col-sm-4{
        padding-left: 15px;
}        
.hrrm-testing .biopsywrap .subheading {
    margin-top: 0px; 
}

}


@media only screen and (min-device-width: 800px) and (max-device-height: 1280px) and (min-resolution: 192dpi)and (-webkit-device-pixel-ratio:2) and (orientation : portrait) {
.home-content .recommend .nccntxt {
    margin-left: 5px;
}
}


/*ipad portrait styles*/

@media (min-width:768px) and (max-width: 992px) {

.home-content .recommend .nccntxt {
    text-indent: 0px;
    margin-left: 7px;
}
.isi-body {
    padding-left: 0px;
} 
.ipad-marginleft10{
    margin-left: 10px !important;
    }
.astericksymb {
    margin-left: -7px;
}

.bulletcontent{
margin-bottom:30px;        
    }

.PROfound_wrap img {
    padding: 30px 0 30px 0 !important;
}

.bullentcontent .robotoegular20{
	font-family: "Roboto-Regular" !important;
	font-size:12px !important;
	color:#004D74; 
	line-height:16px;                
}
.bullentcontent .robotoegular20 li{
line-height:16px;
                    }

.bullentcontent .robotoegularb20{
	font-family: "Roboto-Bold" !important;
	font-size:14px !important;
	color:#004D74; 
	line-height:16px;        
}

.desktop-md{
display:none !important;
    }  
.width75{
width: 64.9% !important;
}        

.width90{
width:84% !important;
    }   
.width55{
width:50.6% !important;
} 

.margintop50 {
    margin-top: 30px;
}

.hrrm-testing .biopsywrap .sectionleft .contentwrap {
    padding-left: 10px;
}
.hrrm-testing .prognastic .recommendImg img {
    position: relative;
    left: 7%;
}                

.hrrm-testing .biopsywrap .contentwrap ul.listcontent li.magenta {
    width: 90%;
}             
.hrrm-testing .biopsywrap .contentwrap .logosect {
    width: 95%;
}
.hrrm-testing .biopsywrap{
/*width: 85%;*/
width: 100%;    
}

.hrrm-testing .biopsycontent .row {
    display: block;
}


.hrrm-testing .biopsywrap .contentwrap .logosect {
    border-bottom: 2px solid #004D74;
    padding-bottom: 15px;
}

.hrrm-testing .biopsywrap .contentwrap .logosect {
    border-bottom: 2px solid #004D74;
    padding-bottom: 15px;
    width: 46% !important;
}

.hrrm-testing .biopsywrap .contentwrap .logosect img {
    border-bottom: 0px dotted #004D74;
    padding-bottom: 0px;
}
.hrrm-testing .biopsywrap .sectionleft .logosect img, .hrrm-testing .biopsywrap .sectionright .logosect img {
    width: auto;
    max-width: 100%;
    float: left;
}
.hrrm-testing .biopsywrap .subheading {
    color: #004D74;
    font-size: 16px;
    font-family: 'Roboto-Bold';
    line-height: 20px;
    margin-top:5px;
}
.hrrm-testing .biopsywrap .subheadingtwo {
    color: #004D74;
    font-size: 18px;
    font-family: 'Roboto-Bold';
    line-height: 20px;
    margin-bottom:4px;
    margin-top:25px;    
}
.hrrm-testing .biopsywrap .wheretxt {
    margin-left: 10px;
}
.PROfound_wrap h3.margintop35{
	margin-top:35px !important;
    padding: 0px 10px 0px !important;
}
.ipadnowrap{
white-space: nowrap;
    }      

.isi{
padding-left: 20px;
}  
}

@media only screen and (max-width: 992px) and (min-width: 961px){
.fullnavigation .navbar-default .navbar-nav>li.dose-management {
    right: 22.5%;
}
.fullheader .list-inline li:nth-child(4) {
    top: 40px;   
}
}

@media only screen and (max-width: 960px) and (min-width: 768px){
.fullheader .list-inline li:nth-child(4) {
    right: 43.5% !important;
    top: 40px;                    
}
.fullnavigation .navbar-default .navbar-nav>li.dose-management {
    right: 24.9%;
}

}



@media (max-width: 767px){
.isi-body ul li::before{
	margin-left: 0;
}
.patient-support .enroll {
   margin: 25px 0px 0px 0px;
}

.patient-support .website-grid .col-xs-12{
 margin: 25px 0px 0px 0px;
            }

.fullnavigation .navbar-default .navbar-nav>li.dose-management {
	right: 0px;
    display: inline-flex;
    width: 100%;
}

.PROfound_wrap .robotbold18txt, .secondary_endpointOS p.robotbold18txt {
    font-family: 'Roboto-Bold'!important;
    font-size: 16px !important;
    line-height: 20px !important;
    color: #000 !important;
}

.hrrm-testing .biopsywrap .basedtxt {
    color: #004D74;
    font-family: 'Roboto-Regular';
    font-size: 16px;
    margin-top: 25px;
    margin-left: 14px;
}
.PROfound_wrap .toggleWrap img {
    max-width: 340px;
    width: 340px;
    margin: 0px;
    margin-left: -65px;
}

.bulletcontent{
margin-bottom:30px; 
    }
.PROfound_wrap h3.margintop35{
margin-top:35px !important;
        }

.bullentcontent .robotoegular20{
	font-family: "Roboto-Regular" !important;
	font-size:12px !important;
	color:#004D74; 
	line-height:16px;                
}
.bullentcontent .robotoegular20 li{
line-height:16px;
    font-size: 16px;
                    }

.bullentcontent .robotoegularb20{
	font-family: "Roboto-Bold" !important;
	font-size:14px !important;
	color:#004D74; 
	line-height:16px;        
}
.PROfound_wrap img {
    padding: 30px 0 30px 0 !important;
}
.desktop-md{
display:none !important;
    } 
.width75{
width: 64.9% !important;
}        

.width90{
width:84% !important;
    }   
.width55{
width:50.6% !important;
} 

.lnht15{
line-height:15px !important;
    }
.hrrm-testing .biopsywrap .biopsycontent {
    background-color: #f2f6f8;
}
.margintop50 {
    margin-top: 25px;
}
.hrrm-testing .biopsycontent .row {
    display: block;
}


.hrrm-testing .biopsywrap .contentwrap .logosect {
    border-bottom: 2px solid #004D74;
    padding-bottom: 15px;
    width: 84% !important;
}

.hrrm-testing .biopsywrap .contentwrap .logosect img {
    border-bottom: 0px dotted #004D74;
    padding-bottom: 0px;
}
.hrrm-testing .biopsywrap .sectionleft .logosect img, .hrrm-testing .biopsywrap .sectionright .logosect img {
    width: auto;
    max-width: 100%;
    float: left;
}
.hrrm-testing .biopsywrap .subheading {
    color: #004D74;
    font-size: 16px;
    font-family: 'Roboto-Bold';
    line-height: 20px;
    margin-top: 5px;
}
.hrrm-testing .biopsywrap .subheadingtwo {
    color: #004D74;
    font-size: 18px;
    font-family: 'Roboto-Bold';
    line-height: 20px;
    margin-bottom:4px;
    margin-top:25px;    
}

.home #maincontent {
    margin-top: 121px !important;
}
.efficacy #maincontent {
    margin-top: 90px !important;
}

.hrrm-testing #maincontent {
    margin-top: 90px !important;
}


.fullheader .logos .logo img {
    max-width: 110px;
    padding-left: 20px;
}
.isi{
    padding-left: 20px;
}                    
.isi-tray.open-state .indications{
 padding-left: 0px;
}
.isi-tray.open-state .isi-body {
    padding-top: 0;
    padding-left: 10px;
}

.fullheader ul.list-inline li:nth-child(2) {
    display: inline-block;
    background-color: #fff;
    margin-left: 8px;
}
.fullheader ul.list-inline li:nth-child(2):after {
    content: "|";
    margin: 0 5px 0px 11px;
}
.fullnavigation .navbar-default .navbar-nav>li:nth-child(5)>a {
    border-bottom: #fff solid 1px;
}

.m-marginleft10{
    margin-left: 10px !important;
    }

#header .indication-selector .header-dropdown ul li.init .child-inner {
    padding-left: 16px !important;
    padding-right: 6px !important;
}
.dosing-page #maincontent {
    margin-top: 92px !important;
}
}

@media only screen and (max-width: 767px) and (min-width: 321px){
.home #maincontent {
    margin-top: 117px !important;
}   
.fullheader .logos .logo {
    padding: 15px 0 17px;
}     
}

@media (max-width: 340px) {
.fullheader .logos .logo img {
    max-width: 102px;
    padding-left: 10px;
}
}

/******************for iphone 6**********************************/
@media only screen and (min-device-width : 375px) and (max-device-width : 667px) { 
  .PROfound_wrap .toggleWrap img {
    margin-left: -90px;
}   
}


@media only screen and (min-device-width : 375px) and (max-device-width : 667px) and (width : 667px) and (height : 375px) and (orientation : landscape) and (color : 8) and (device-aspect-ratio : 375/667) and (aspect-ratio : 667/375) and (device-pixel-ratio : 2) and (-webkit-min-device-pixel-ratio : 2)
{
.fullnavigation .navbar .navbar-collapse {
    overflow-y: scroll;
    height: 220px;
    z-index: 999;
}
 #header .search-box>.search form input#search {
    background-color: #b74583;
    z-index: 99999;
 }                               
}

@media only screen and (max-width: 767px) and (min-width: 320px) and (orientation : landscape){                
.fullnavigation .navbar .navbar-collapse {
    overflow-y: scroll;
    height: 220px;
    z-index: 999;
}
#header .search-box>.search form input#search {
    background-color: #b74583;
    z-index: 99999;
 }
}                    





/******************for iphone 6+ **********************************/

@media only screen and (min-device-width : 414px) and (max-device-width : 736px){
.PROfound_wrap .toggleWrap img {
    margin-left: -125px;
}                
} 


/******************for iphone 5**********************************/
@media only screen and (device-width: 320px) and (orientation :portrait){
.home #maincontent {
    margin-top: 122px !important;
} 

.patient-support .website-grid .content-right a.font10 {
    font-size: 10px !important;
}
}        


/****----------samsung 6plus-------************/

@media only screen and (min-device-width : 360px) and (max-device-width : 640px) and (-webkit-min-device-pixel-ratio : 3) {
.hrrm-testing .container-center {
    padding-right: 12px;
}
}                        



@media only screen and (max-width: 365px) and (min-width: 321px){
.hrrm-testing .blue_bg_whoicon {
   width: 290px;

}
.hrrm-testing .blue_bg_whaticon {
    width: 290px;
}
.piechart img {
    margin: 0 auto;
    width: 98%;
}
#modal-content-wrapper #indication-select .modal-dialog .modal-content {
    width: 95%;
}                                                
#header .indication-selector .header-dropdown ul li.init .child-inner {
    padding-left:7px !important;
    padding-right:6px !important;                                        
}
}           

@media only screen and (max-width: 340px) and (min-width: 321px){
.home-content .recommend h2.subheading {
    left: 41px;
}
}                         


@media only screen and (max-width: 320px) and (min-width: 320px){
#header .indication-selector .header-dropdown ul li.init .child-inner {
    padding-left:10px !important;
    padding-right:6px !important;                                        
}
}                        


@media only screen and (max-width: 370px) and (min-width: 366px){
#header .indication-selector .header-dropdown ul li.init .child-inner {
    padding-left:7px !important;
    padding-right:6px !important;                                        
}
}           

@media only screen and (max-width: 352px) and (min-width: 348px){
.az-logo a {
    margin: 9px -20px 0 0;
}
}

@media (max-width: 1280px) and (min-width: 1024px){
.home .callouts {
    margin: 47px -4% 0 0;
}    
}                           

@media only screen and (min-width: 1024px) and (max-width: 1350px) {
	.home .landing-hero-image{
		    height: calc(100vw * 0.28);
	}
	.home .callouts {
		margin: 4.5% 0 0 0 !important;
	}
}