/* START New fonts for Proper 3 */


@font-face {
    font-family: 'Roboto-Black';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black.eot?#iefix') format('embedded-opentype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black.woff2') format('woff2'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black.woff') format('woff'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black.ttf') format('truetype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black.svg#Roboto-Black') format('svg');
    font-weight: 900;
    font-style: normal;
    font-display: swap;
}

@font-face {
    font-family: 'Roboto-Light';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Light.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Light.eot?#iefix') format('embedded-opentype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Light.woff2') format('woff2'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Light.woff') format('woff'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Light.ttf') format('truetype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Light.svg#Roboto-Light') format('svg');
    font-weight: 300;
    font-style: normal;
    font-display: swap;
}

@font-face {
    font-family: 'Roboto-BlackItalic';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-BlackItalic.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-BlackItalic.eot?#iefix') format('embedded-opentype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-BlackItalic.woff2') format('woff2'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-BlackItalic.woff') format('woff'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-BlackItalic.ttf') format('truetype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-BlackItalic.svg#Roboto-BlackItalic') format('svg');
    font-weight: 900;
    font-style: italic;
    font-display: swap;
}

@font-face {
    font-family: 'Roboto-BoldItalic';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-BoldItalic.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-BoldItalic.eot?#iefix') format('embedded-opentype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-BoldItalic.woff2') format('woff2'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-BoldItalic.woff') format('woff'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-BoldItalic.ttf') format('truetype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-BoldItalic.svg#Roboto-BoldItalic') format('svg');
    font-weight: bold;
    font-style: italic;
    font-display: swap;
}

@font-face {
    font-family: 'Roboto-Bold';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Bold.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Bold.eot?#iefix') format('embedded-opentype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Bold.woff2') format('woff2'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Bold.woff') format('woff'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Bold.ttf') format('truetype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Bold.svg#Roboto-Bold') format('svg');
    font-weight: bold;
    font-style: normal;
    font-display: swap;
}

@font-face {
    font-family: 'Roboto-Italic';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Italic.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Italic.eot?#iefix') format('embedded-opentype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Italic.woff2') format('woff2'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Italic.woff') format('woff'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Italic.ttf') format('truetype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Italic.svg#Roboto-Italic') format('svg');
    font-weight: normal;
    font-style: italic;
    font-display: swap;
}

@font-face {
    font-family: 'Roboto-Black_1';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black_1.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black_1.eot?#iefix') format('embedded-opentype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black_1.woff2') format('woff2'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black_1.woff') format('woff'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black_1.ttf') format('truetype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black_1.svg#Roboto-Black') format('svg');
    font-weight: 900;
    font-style: normal;
    font-display: swap;
}

@font-face {
    font-family: 'Roboto-MediumItalic';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-MediumItalic.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-MediumItalic.eot?#iefix') format('embedded-opentype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-MediumItalic.woff2') format('woff2'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-MediumItalic.woff') format('woff'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-MediumItalic.ttf') format('truetype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-MediumItalic.svg#Roboto-MediumItalic') format('svg');
    font-weight: 500;
    font-style: italic;
    font-display: swap;
}

@font-face {
    font-family: 'Roboto-LightItalic';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-LightItalic.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-LightItalic.eot?#iefix') format('embedded-opentype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-LightItalic.woff2') format('woff2'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-LightItalic.woff') format('woff'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-LightItalic.ttf') format('truetype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-LightItalic.svg#Roboto-LightItalic') format('svg');
    font-weight: 300;
    font-style: italic;
    font-display: swap;
}

@font-face {
    font-family: 'Roboto-ThinItalic';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-ThinItalic.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-ThinItalic.eot?#iefix') format('embedded-opentype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-ThinItalic.woff2') format('woff2'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-ThinItalic.woff') format('woff'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-ThinItalic.ttf') format('truetype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-ThinItalic.svg#Roboto-ThinItalic') format('svg');
    font-weight: 100;
    font-style: italic;
    font-display: swap;
}

@font-face {
    font-family: 'Roboto-Medium';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Medium.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Medium.eot?#iefix') format('embedded-opentype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Medium.woff2') format('woff2'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Medium.woff') format('woff'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Medium.ttf') format('truetype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Medium.svg#Roboto-Medium') format('svg');
    font-weight: 500;
    font-style: normal;
    font-display: swap;
}

@font-face {
    font-family: 'Roboto-Regular';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Regular.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Regular.eot?#iefix') format('embedded-opentype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Regular.woff2') format('woff2'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Regular.woff') format('woff'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Regular.ttf') format('truetype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Regular.svg#Roboto-Regular') format('svg');
    font-weight: normal;
    font-style: normal;
    font-display: swap;
}

@font-face {
    font-family: 'Roboto-Thin';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Thin.eot');
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Thin.eot?#iefix') format('embedded-opentype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Thin.woff2') format('woff2'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Thin.woff') format('woff'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Thin.ttf') format('truetype'),
        url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Thin.svg#Roboto-Thin') format('svg');
    font-weight: 100;
    font-style: normal;
    font-display: swap;
}





/* END New fonts for Proper 3 */



@font-face {
	font-family: 'Roboto-Medium';
	src:  url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/Roboto-Medium.woff') format('woff');
	font-weight: normal;
	font-style: normal;
}
@font-face {
    font-family: 'MyriadPro-SemiBold';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/myriadpro-semibold.woff') format('woff');
    font-weight: normal;
    font-style: normal;
}
@font-face {
    font-family: 'MyriadPro-Regular';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/myriadpro-regular.woff') format('woff');
    font-weight: normal;
    font-style: normal;
}
span.text-indent {
	text-indent: 10px;
    display: block;
}
.desk-callout-inner-pdleft {
	padding-right: 80px !important;
}
.ital-space{
	padding-right: 1px;
}
.Roboto-BlackItalic{
font-family:'Roboto-BlackItalic';
    }
.final-os-itt.mobile {
    font-family: 'MyriadPro-Bold';
    font-size: 14.2px;
    line-height: 12px;
    padding-bottom: 20px;        
}
.final-os-itt .pink-sec{
	color: #990064;
}
.ps3 .flag-txt h1 {
    font-family: 'Roboto-Italic';
}
.moa-combi.container-center { padding-left : 3px !important;}
p.skew-before-txt {
    margin-top: 15px;
    color: #004D74;
    font-family: 'Roboto-Bold';
    font-size: 18px;
    line-height: 20px;
}
/**/
.safety-tolerability .adverseImg img {
    max-width: 1012px!important;
    margin-left: 0px;
    width: 1012px!important;
}
.safety-tolerability .labimg img {
    max-width: 1012px!important;
    margin-left: 0px;
    width: 1012px!important;
}/**/
p.footnote.fin-an {
    font-size: 13px;
    line-height: 16px;
    font-family: 'MyriadPro-Regular';
    text-indent: 0;
}
p.fin-analys-head{
	font-size: 14px;
    line-height: 16px;
    color: #991464;
    font-family: 'MyriadPro-Bold';
}
.crash-handler{
	padding-right: 2px;
}
.mechanism-of-action .moa-combi  .end-notes p.footnotes:last-child{
	    text-indent: -5px;
}
.combi-patient-profile .desk-callout-but span:after{
	right: -40px;
}
.combi-patient-profile .desk-callout-but span.ar-rights::after {
    right: -118px!important;
}
.pink_eyebrow.color-pulm {
    background: #990064 0% 0% no-repeat padding-box!important;
}
.cpy-right{ margin-left: 4px; }
.sized-cpyrt {
    font-size: 100% !important;
    top: 0;
}
sup.str-top {
    font-size: 23px;
    top: -5px;
}
.mechanism-of-action .moa-combi .end-notes .footnotes:nth-child(2),
.mechanism-of-action .moa-combi .end-notes .footnotes:nth-child(1) {
    font-family: 'MyriadPro-Bold';
    margin-bottom: 10px;
}

.moa-mono .footnote:first-child{
	font-size: 10px !important;
    line-height: 12px !important;
    font-family: 'MyriadPro-Bold';
    margin-bottom: 6px;
}	

.moa-mono .footnote:nth-child(2){
	font-size: 10px !important;
    line-height: 11px !important;
    font-family: 'MyriadPro-Regular';
}
.pink-var{
    color: #FF00EB;
    }
.pink-text{
    color: #FF00FF !important;
}
span.pink-text:before{
    content:'[';
}
span.pink-text:after{
    content:']';
}
/**patient-profile tabs**/
.mono-foots,
.patient-profiles .mono-patient-profile{
	display: none;
}
.patient-profiles  .tab-head-container {
	background: #990064;
    transform: skewX(170deg);
    margin-top: 25px;
    margin-bottom: 35px;
    padding: 14px 28px 10px;
}
.patient-profiles .tab-links > nav >.nav-tabs{
	border: none;
}
.patient-profiles .tab-links .link-parent {
    display: inline-block;
    transform: skewX(170deg);
}
.patient-profiles .tab-active,
.patient-profiles .tab-links > nav a.nav-item:active, 
.patient-profiles .tab-links > nav a.nav-item:focus, 
.patient-profiles .tab-links > nav a.nav-item:hover {
    background-color: #FFFFFF !important;
    color: #990064 !important;      
}
.patient-profiles #tab-opener-2 > a {
    padding: 9px 30px 13px;
    display: inline-block;
    max-width: 197px;
    text-align: center;
}
.patient-profiles #tab-opener-1 > a {
	/*padding: 9px 12px 13px;*/
    padding: 9px 11px 13px;
    display: inline-block;
    max-width: 197px;
    text-align: center;
}
.patient-profiles .tab-pane.active.in{
	display: block !important;
}
.patient-profiles .tab-pane.fade{
	display: none;
}
.patient-profiles .tab-head-container .tabs-body{
	display: flex;
   display: -webkit-box;
  display: -webkit-flex;
  display: -ms-flexbox;
}
.patient-profiles .tab-head-container .tab-heading h1{
	font-size: 30px;
	font-family: 'Roboto-Bold';
	font-style: italic;
	color: #FFFFFF;
} 
.patient-profiles .tab-links > nav  a.nav-item {
	padding: 20px 30px 15px;
    color: #99006475;
    font-family: 'Roboto-Bold';
    font-size: 18px;
    background-color: #E3C8D7;
    text-decoration: none;
        line-height: 20px;
}

/**NCCN tabs**/
.mono-foots,
.nccn-guidelines .mono-patient-profile{
	display: none;
}
.nccn-guidelines  .tab-head-container {
	background: #990064;
    transform: skewX(170deg);
    margin-top: 25px;
    margin-bottom: 35px;
    padding: 14px 28px 10px;
}
.nccn-guidelines .tab-links > nav >.nav-tabs{
	border: none;
}
.nccn-guidelines .tab-links .link-parent {
    display: inline-block;
    transform: skewX(170deg);
}
.nccn-guidelines .tab-active,
.nccn-guidelines .tab-links > nav a.nav-item:active, 
.nccn-guidelines .tab-links > nav a.nav-item:focus, 
.nccn-guidelines .tab-links > nav a.nav-item:hover {
    background-color: #FFFFFF !important;
    color: #990064 !important;      
}
.nccn-guidelines #tab-opener-2 > a {
    padding: 9px 30px 13px;
    display: inline-block;
    max-width: 197px;
    text-align: center;
}
.nccn-guidelines #tab-opener-1 > a {
	/*padding: 9px 12px 13px;*/
    padding: 9px 11px 13px;
    display: inline-block;
    max-width: 197px;
    text-align: center;
}
.nccn-guidelines .tab-pane.active.in{
	display: block !important;
}
.nccn-guidelines .tab-pane.fade{
	display: none;
}
.nccn-guidelines .tab-head-container .tabs-body{
	display: flex;
   display: -webkit-box;
  display: -webkit-flex;
  display: -ms-flexbox;
}
.nccn-guidelines .tab-head-container .tab-heading h1{
	font-size: 30px;
	font-family: 'Roboto-Bold';
	font-style: italic;
	color: #FFFFFF;
} 
.nccn-guidelines .tab-links > nav  a.nav-item {
	padding: 20px 30px 15px;
    color: #99006475;
    font-family: 'Roboto-Bold';
    font-size: 18px;
    background-color: #E3C8D7;
    text-decoration: none;
        line-height: 20px;
}


/**NCCN tabs**/

/**patient-profile tabs**/
.btm-txt .subnote span {
   font-family: 'MyriadPro-Bold' !important;
}
.pink-call-txt {
    background: #9904641A;
    padding: 12px 22px;
    transform: skewX(-5deg);
    text-align: center;
    margin-bottom: 12px;
    margin-top: 20px;
}
.pink-call-txt.pink-call-txt-pad {
    padding: 12px 20px;
}
.pink-call-txt span {
	font-family: 'Roboto-Bold';
    color: #333333;
	display: inline-block;
   transform: skewX(4deg);
        line-height: 20px;
}
.base-line h5{
	font-size: 16px !important;
	text-align: left;
	margin-bottom: 20px;
}
.base-line .heading p{
	text-align: left;
}
p.footnote.subnote.bold.blk-bld {
    font-size: 16px !important;
    line-height: 20px !important;
    font-family: 'Roboto-Bold';
	color: #000000 !important;
}
.deskcallout-first .desk-callout-but span:after{
	    border: 3px solid #B2D234;
        border-left: none;
    border-bottom: none;
}
.treatpath-diagram img{
	width: 100%;
}
p.treat-studytxt,
.trate-path-head{
	color: #004D74;
    font-family: 'Roboto-Bold';
}
.container-center.chart-txts{
	color: #004D74;
    text-align: center;
}
p.treat-disclaimer{
	font-family: 'Roboto-Regular';
}
.patient-profiles .end-banner-patient .william-opt, 
.patient-profiles .end-banner-patient .joe-opt {
    background-color: #801852;
}
.patient-profiles .end-banner-patient p {
    color: #FFFFFF;
}
.patient-profiles .joe .pat-detail img.desktop {
    max-width: 338px;
}
.patient-profiles .pat-detail img.desktop{
	max-width: 392px;
}
.pat-detail.pat-detail2 { padding-left: 25px;}
.patient-profiles .propel-content .btn-banner {
    background-color: #801852;
}
.patient-profiles .combi-patient-profile .patient-profile-wrap{
	background-color: #F8FFF7;
}
.patient-profiles .combi-patient-profile .patient-profile-wrap h4{
	color: #801852;
    font-family: 'Roboto-Bold';
}
.patient-profiles .combi-patient-profile .med-facts{
	color: #59595B;
}
.patient-profiles .combi-patient-profile .med-facts .mCRPCw { width : 520px;}
.patient-profiles .combi-patient-profile .med-facts .width500{
	width : 500px;
}
.patient-profiles .combi-patient-profile p.fact-head{
	margin-bottom: 0;
}
.patient-profiles .combi-patient-profile .med-facts li {
    /*padding-bottom: 5px;*/
}
.patient-profiles .combi-patient-profile .propel-content .btn-banner {
    background-color: #990064;
    margin-top: 20px;
    max-height: 45px;
    max-width: 500px;
}
.patient-profiles .mono-patient-profile .propel-content .btn-banner{
 max-width: 500px;
}
.patient-profiles .combi-patient-profile .skew-maroon-head {
    background-color: #990064;
    padding: 5px 60px;
    transform: skewX(170deg);
    margin: 30px auto 35px;
    margin-left: 8px;
    box-shadow: 10px 10px 0px 1px #b2d234;
    max-width: 447px;            
}
.footnotes.footnotes1 {
    display: none;
}
.patient-profiles .combi-patient-profile .skew-maroon-head h2 {
    color: #ffffff;
    margin: 10px 0;
    transform: skewX(10deg);
    font-size: 20px;
    line-height: 22px;
    font-family: "Roboto-Bold";
    padding-left: 0px;
    text-align: center;
}
.patient-profiles .combi-patient-profile ul.profile-cont {
    color: #333333;
    font-family: 'Roboto-Regular';
}
.skew-maroon-head.david-skew p{
	color: #FFFFFF;
	font-family: 'Roboto-Bold';
}
.skew-maroon-head.david-skew {
	box-shadow: 10px 5px 0px 1px #b2d234;
}

.home .landing-content{
	background-color: #FFFFFF;
}
.landing-content.landing-content-pad{
margin-bottom:-25px;
}
.home .callouts .callout{
	    background-color: #990064;
		border: solid 3px #990064;
}
.now-approve{
	background: #B2D234;
}
.flag-txt{
    background: #990064;
    color: #FFFFFF;
}
.flag-txt sup{
	margin-left: 3px;
    font-family:'Roboto-Regular';
}
.now-approve p{
	color: #004D74;
    font-family: 'Roboto-Bold';
}

.homepg-callout{
	float: right;
	/*max-width: 230px;*/
    max-width: 232px;
	margin: 4.5% 5% 0 0; 
}
.homepg-callout.desk-callout.desk-callout-left {
    margin: 4.5% -1% 0 0;
    width: 280px!important;
}
.homepg-callout .deskcallout-second{
    position: relative;
    right: 10px;
}   
.patient-profiles .desk-callout,
.homepg-callout .desk-callout {
	background-color: #990064;
	margin-bottom: 15px;
	transform: skewX(-10deg);
   padding: 4px 15px 7px 12px;
}
.desk-callout.deskcallout-first.desk-calloutss1 {
    padding: 4px 9px 7px 11px;
}
.desk-callout-width{
width:281px!important;
}
.select-patients {
    color: #fff;
    position: absolute;
    left: 74px;
    bottom: 0;
    font-size: 13px;
}
p.footnote.marginbottom20.marginbottom20-align {
    font-size: 16px !important;
    line-height: 20px !important;
    margin-bottom: 20px!important;
    color: #000!important;
}
.patient-profiles .desk-callout{
		float: right;
		max-width: 230px;
	}
.mono-patient-profile .desk-callout-but span:after{
	right: -99px;
}
.desk-callout.deskcallout-second {
    background-color: #801852;
}
.desk-callout.deskcallout-second .desk-callout-but{
    color: #801852;
}
.desk-callout-but {
    background-color: #FFFFFF;
    padding: 6px 6px;
	color: #990064;
    font-family: 'Roboto-Bold';
    font-size: 20px;
    letter-spacing: -0.3px;
    line-height: 20px;
    display: block;    
}
.desk-callout-inner p{
	font-size: 14px;
    color: #FFFFFF;
    line-height: 21px;
    margin: 0;
    transform: skewX(10deg);
    font-style: italic;
    padding: 2px 0px 5px;
    font-family: 'Roboto-BlackItalic';
}
p.font-boldn {
    font-family: 'Roboto-Bold';
}
.desk-callout-inner.comb-bold {
    font-family: 'Roboto-Bold';
}
.desk-callout-but:hover { 
    text-decoration: none;
	color: #990064;
}
.desk-callout-but span{ position: relative; }
.desk-callout-but span:after{
    content: '';
    position: absolute;
    border: 3px solid #801852;
    border-left: none;
    border-bottom: none;
    width: 14px;
    height: 14px;
    right: -65px;
    transform: rotate(40deg);
    top: 5px;
}

p.robo-bold.robo-bold-lineh {
    line-height: 14px!important;
}
.desk-callout-but-arrow span:after{right: -94px!important;}
.desk-callout-but-arrow1 span:after{right: -120px!important; }
.homepg-callout .deskcallout-second .desk-callout-but span:after{
	right: -45px;
}
.color-cg {
    color: #990064!important;
}
.homepg-callout .deskcallout-first .desk-callout-but span:after{
	border: 3px solid #B2D234;
    border-left: none;
    border-bottom: none;                
}
.patient-profiles .deskcallout-first .desk-callout-but,
.homepg-callout .deskcallout-first .desk-callout-but{
	border: 2px solid #B2D234;
}
.deskcallout-second a.desk-callout-but{
	border: 2px solid #FFFFFF;
}
.hrrm-testing .pink_eyebrow {
    background: #801852 0% 0% no-repeat padding-box;
}
.safety-combination-theraphy .pink_eyebrow{
	background: #990064 0% 0% no-repeat padding-box;
     /*   background: #801852 0% 0% no-repeat padding-box;*/
}
.safety-combination-theraphy .safetylistsect ul,
.safety-combination-theraphy .footnote{
	color: #333333;
}
.safety-combination-theraphy .section-one{
	   background-color: #FFFFFF;
}
.hrrm-testing .propel-box{
	background: #801852;
	font-family: 'Roboto-Bold';
    transform: skewX(-10deg);
    color: #FFFFFF;
    text-align: center;
    padding: 12px;
}
.hrrm-testing .bio-txt {
    color: #801852;
    font-family: "Roboto-bold";
}
.hrrm-testing .bio-txt sup{
	margin-left: 3px;
}
.hrrm-testing .container-center.skew-maroon-box {
    background: #990064;
    font-family: 'Roboto-Bold';
    transform: skewX(-10deg);
    color: #FFFFFF;
    text-align: center;
    padding: 12px;
    box-shadow: 8px 8px 0px 1px #b2d234;
}
.hrrm-testing .container-center.skew-maroon-box em{
	transform: none;
}
.hrrm-testing .section-one{
	background: #FFFFFF;
}
.hrrm-testing .whytest-flex {
    display: flex;
    justify-content: left;
}
.hrrm-testing .chart-sec-head{
	color: #004D74;
	font-family: 'Roboto-Bold';
}
.hrrm-testing .pink-bg {
    background: #801852;
    color: #FFFFFF;
    font-family: "Roboto-bold";
}
.hrrm-testing .container28{
	background: #FFFFFF;
}
.hrrm-testing .pink-head {
    color: #801852;
    font-family: "Roboto-bold";
}  
.hrrm-testing .pinkhead-cont {
    color: #004D74;
    font-family: "Roboto-Regular";
}

.hrrm-testing .propel-content .btn-banner{
	float: none;
	max-width: fit-content;
}
.hrrm-testing .propel-content:nth-child(2){
	color: #801852;
}
.hrrm-testing .propel-content:nth-child(1) .btn-banner{
	box-shadow: 4px 4px 0px 1px #b2d234;
}

.heading-1{
	font-family: "Roboto-bold";
    color: #004D74;
}
.img-desc {
    font-family: "Roboto-Regular";
    color: #004D74;
}
.img-desc .high-txt{
	font-family: "Roboto-bold";
}
.sect-3 .footnote{  
	color: #333333 !important;
    font-family: "Roboto-bold";
}
.mechanism-of-action .common-head{
	color: #004D74;
	font-family: 'Roboto-Bold';
}
.mechanism-of-action .end-notes .footnotes {
    font-family: 'Roboto-Regular';
    color: #333333;
}
.moa-combi .moa-process{
	display: flex;
    justify-content: center;
    align-items: center;
}
.green-cont.theraphy-steps{
	background: #B2D234;
    font-family: 'Roboto-Bold';
	color: #004D74;
}

.grey-cont.theraphy-steps {
    background: #56849F;
	font-family: 'Roboto-Bold';
	color: #FFFFFF;
}
.plus-img{
	z-index: 1;
}
.pageend-navigator .propel-content:nth-child(2) .btn-banner {
    background-color: #801852;
}
.reference,
.footnote{
	font-size: 16px !important;
    line-height: 20px !important; 
}
p.footnote.footnote-nw-font {
    font-size: 10px !important;
    line-height: 12px !important;
}
.monotherapy-footnote {
	font-size: 10px !important;
    line-height: 12px !important;
}
.patient-profiles .med-facts {
    color: #59595b;
}
.safety-combination-theraphy .footnote{
	/*color: #333333 !important;*/
}
.safety-tolerability .monotherapy-footnote{
color: #333333 !important;
}

.patient-profiles .combi-patient-profile .patient-profile-wrap li{
	list-style-type: none;
}
.patient-profiles .combi-patient-profile .patient-profile-wrap li:before{ 
	    content: "•";
    font-size: 18px;
    position: relative;
    left: -10px;
}

.dosing-mono-3 #footer > div.footer-parsys.parsys > div > div.container-center.footnote_end.m-paddingLef20.margintop0 {
    padding-left: 5px;
}

@media (min-width: 1004px) and (max-width: 1024px){
.fullnavigation .navbar-default .navbar-nav{
	    justify-content: center;
}	
}

@media (min-width: 1004px){
.fullnavigation .navbar li.testing{
	position: relative;
}
.fullnavigation .navbar li.testing ul.multi-level li > a {
    max-width: 338px;
}

.fullnavigation .navbar li.testing ul.multi-level li > a{
	font-family: 'Roboto-Regular';
    color: #FFFFFF;
    white-space: normal;
    text-align: left;
}
.fullnavigation .navbar li.testing ul.multi-level li:last-child{
	    background: #FFFFFF !important;
    opacity: 0.95;
}
.fullnavigation .navbar li.testing ul.multi-level li:last-child > a{
	color: #000000 !important
}
.fullnavigation .navbar li.testing ul.multi-level .select-txt{
	    border-radius: 0 0 10px 10px;
}
}

/*****desktop******/
@media (min-width: 992px){
.patient-profiles .mono-patient-profile .medical-hist{
	margin-top: 38px;
}    
p.skew-before-txt{
	padding-left: 30px;
    font-size: 18px;
    line-height: 20px;
}
img.img-responsive.desktop.os-kmcurve{
	max-width: 806px;
}
img.img-responsive.desktop.os-kmcurve.os-kmcurve-n {
    max-width: 100%!important;
}
img.img-responsive.desktop.os-event{
	max-width: 435px;
}
.dose-mod-img{
	max-width: 711px;
    margin: 0 auto;
}
.flag-txt h1{
    margin: 0;
    font-size: 16px;
    line-height: 20px;
    letter-spacing: -0.2px;
}
.monotherapy.profound-efficacy .magenta_eyebrow h1 {
    font-size: 30px;
    padding-left: 10px;
}
h1.container-center.pr-p3.pr-p3-pad {
   letter-spacing: -0.02em;
   font-family: 'Roboto-BlackItalic';
}
.sensit-analysis  .margintop20.ipadp-mtop20.paddingLeft5,
.prim-endp .margintop20.ipadp-mtop20.paddingLeft5{
	margin-top: 25px;
}
	.home .callouts .callout{
		width: 229px;
		height: 68px;
	}
.approved-callout{
	/* max-width: 496px; */
	max-width: 526px;
    position: relative;
    left: -10px;
        top: 10px;        
}
.dose-interrupts.dose-interruptss-new{
    max-width: 318px!important;
    width: 100%;
}
.dose-reduces.dose-reducess-new{
    max-width: 658px!important;
    width: 100%;
}
.init-reduce.init-reduce-to1 {
    padding: 10px 21px 18px 28px!important;
}
.final-reduce.final-reduce-to1 {
    padding: 10px 21px 18px 28px!important;
}
.now-approve{
	max-width: 269px;
    transform: skewX(-10deg);
    position: relative;
    top: 7px;
    z-index: 1;    
}        
.now-approve p{
	font-size: 20px;
	line-height: 21px;
    padding: 8px 10px 8px 69px;
    margin-bottom: 0;
    transform: skewX(10deg);        
}
.flag-txt{
	    padding: 18px 15px 4px 71px;
    transform: skewX(-12deg);
    line-height: 20px;
    height: 88px; 
    margin-top: 37px;
}
.flag-txt div{
	transform: skewX(10deg);
    font-family: 'Roboto-Medium';
}
.homepg-callout.mob-callout{
	display: none;
}
.home .footnote{
	font-size: 16px !important;
    line-height: 20px;
}
.home .reference{
	font-size: 16px;
    line-height: 20px;
}
.patient-profiles .end-banner-patient p{
	    padding: 9px 42px;
}
.patient-profiles .propel-content .btn-banner{
	margin-top: 55px;
}
.select-patients {
    color: #fff;
    position: absolute;
    left: 74px;
    bottom: 0;
    font-size: 13px;
}

.monotherapy3 p.color-brown25, p.color-brown31 {
    padding-top: 21px;
}
.monotherapy3 p.Primary_endpoint-text-blue31.Primary_endpoint-text-blue311 {
    padding-bottom: 23px;
}

}


@media (min-width: 1365px){
.patient-profiles .combi-patient-profile .patient-profile-wrap > .container-center {
    padding-left: 5px;
    padding-right: 5px;
    max-width: 1280px;
}
.patient-profiles .combi-patient-profile .patient-profile-wrap{
	/*padding-left: 12%;*/
	padding-left: 17%;
}
.combi-patient-profile .joe.col-xs-12.col-sm-6{
	/*width: 48%;*/
    width: 42%;
}
.combi-patient-profile .medical-hist.desktop.col-xs-12.col-sm-6 {
    width: 52%;
}
.patient-profiles .combi-patient-profile .medical-hist.desktop .joe-history div:last-child .med-facts ul li:last-child{
	    white-space: nowrap;
}
/*.mono-patient-profile .medical-hist.desktop{
	max-width: 1330px;
	padding-left: 5%;
}*/

.mono-patient-profile .medical-hist.desktop .container-center{
    margin: 0 auto 0 auto;
    max-width: 1130px;
    padding-left: 5.5%;
}
.custom-split {
    width: 450px;
}
.custom-split2{
	width: 470px;
}
.patient-profiles .mono-patient-profile .joe-history, 
.patient-profiles .mono-patient-profile .william-history{
	height: 485px;
}    
}

@media (min-width: 1024px){
	.home .landing-hero-image{
		background-image:url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/propel/header-d.jpg);
	}
    .home.ps3 .landing-hero-image{
		background-image:url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/propel/header-d-3.jpg);
	}
}

@media (max-width: 767px){
.safety-combination-theraphy .platinum_chart.container-center.mobile.labimg{
	margin-top: 0;
}    
.hrrm-testing .biopsywrap .sectionleft .logosect img, .hrrm-testing .biopsywrap .sectionright .logosect img {
    max-width: 282px;
}    
.now-approve p{
	margin-bottom: 0;
    text-align: center;
    font-size: 18px;
    padding: 6px 10px 2px;
    line-height: 21px;
}
.flag-txt.flag-text-nw {
    padding: 10px 19px 6px;
}

.flag-txt{
	font-size: 16px;
    line-height: 20px;
    padding: 10px 16px 6px;
}

.patient-profiles .tab-head-container .tabs-body {
    flex-direction: column;
}
.patient-profiles .tab-head-container {
    transform: none;
}
.patient-profiles .tab-heading {
    order: 1;
}
.patient-profiles .tab-head-container{
	padding-top: 0;
    text-align: center;                                        
}
.patient-profiles .tab-head-container .tab-heading h1{
	font-size: 24px;
	line-height: 30px;
    margin: 30px auto 26px;  
    text-align: left;
}
.patient-profiles #tab-opener-1 > a,
.patient-profiles #tab-opener-2 > a {
	font-size: 16px;
	line-height: 20px;
    max-width: 190px;                                        
}
.patient-profiles div#nav-tab{ 
     display: flex; 
    justify-content: center;
}
.patient-profiles #tab-opener-1 > a{
	padding: 10px 18px 10px;
}                                                                                
.patient-profiles #tab-opener-2 > a{
	padding: 10px 22px 10px;
        margin-left: 3px;                                        
}
.patient-profiles .tab-head-container{
	padding: 14px 18px 10px;
}
.patient-profiles .tab-head-container {
    margin-top: 0;
    padding-top: 0;
}
.patient-profiles .tab-head-container {
    background: #990064;
}

/******NCCN Tabs***********/
.nccn-guidelines .tab-head-container .tabs-body {
    flex-direction: column;
}
.nccn-guidelines .tab-head-container {
    transform: none;
}
.nccn-guidelines .tab-heading {
    order: 1;
}
.nccn-guidelines .tab-head-container{
	padding-top: 0;
    text-align: center;                                        
}
.nccn-guidelines .tab-head-container .tab-heading h1{
	font-size: 24px;
	line-height: 30px;
    margin: 30px auto 26px;  
        text-align: left;            
}
.nccn-guidelines #tab-opener-1 > a,
.nccn-guidelines #tab-opener-2 > a {
	font-size: 16px;
	line-height: 20px;
    max-width: 190px;                                        
}
.nccn-guidelines div#nav-tab{ 
     display: flex; 
    justify-content: center;
}
.nccn-guidelines #tab-opener-1 > a{
	/*padding: 10px 18px 10px;*/
    padding: 10px 3px 10px;
}                                                                                
.nccn-guidelines #tab-opener-2 > a{
	padding: 10px 22px 10px;
        margin-left: 3px;                                        
}
.nccn-guidelines .tab-head-container{
	padding: 14px 18px 10px;
}
.nccn-guidelines .tab-head-container {
    margin-top: 0;
    padding-top: 0;
}
.nccn-guidelines .tab-head-container {
    background: #990064;
}
/******NCCN Tabs***********/
.select-patients {
    left: 26px;
}


}    

@media (max-width: 1023px){
	.home .landing-hero-image{
            height: calc(100vw * 0.65);
			background-image:url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/propel/header-m.jpg);
	}
    .home.ps3 .landing-hero-image{
            height: calc(100vw * 0.65);
			background-image:url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/propel/header-m-3.jpg);
	}
 .safety-combination-theraphy .platinum_chart.container-center.mobile.labimg{
	margin-bottom: 40px;
    margin-top: 18px;
}    
.safety-combination-theraphy #footer .footnote{
	margin-bottom: 20px;
}
p.footnote.marginbottom20.abi-new{
    margin-bottom: 20px!important;
}

}

@media (max-width: 991px){
.safety-tolerability .section-two .footnotecontiner{
	/*margin-top: -20px;*/
/* margin-top: -49px;*/
   /*margin-top: -29px;*/
   margin-top: -51px;
}
 p.footnote.monotherapy-footnote.mar-top{
   margin-top: 11px!important;
}
            .pink_eyebrow.color-browns {
    background: #801852 0% 0% no-repeat padding-box;
}
.safety-combination-theraphy .section-one .footnotecontiner.container-center{
	/*margin-top: 20px;*/

       margin-top: -45px;
}
p.skew-before-txt{
	padding: 0 10px;
}
img.img-responsive.desktop.os-event {max-width: 435px;}
.moa-mono .footnote:first-child{
	font-size: 12px !important;
    line-height: 14px !important;
}	
	
.moa-mono .footnote:nth-child(2){
	font-size: 12px !important;
    line-height: 14px !important;
        font-family: 'MyriadPro-Regular';
}   
.space1 {
    padding-left: 5px;
}
p.robotoegularb20.margintop30.first-list.first-list1 {
    padding-bottom: 13px!important;
}
.moa-mono .footnote:nth-child(3){
    text-indent: -5px;
} 
.dosing-combination .reference .container-center.inner-wrapper {
    padding-left: 0;
}    
.iit-txt{
	line-height: 18px;
}    
.cont-3-head {
    margin-bottom: 12px !important;
}    
.pink-call-txt span{
	text-align: left;
}
.pink-call-txt{
	padding: 12px 18px;
}    
p.footnote.subnote.bold.blk-bld {
    font-size: 18px !important;
    padding-right: 10px;  
        padding-top: 0;
    margin-bottom: 20px;    
}    
p.footnote.subnote.bold.blk-bld.marginbottom0.blk-blds {
    font-size: 16px!important;
    color: #525252!important;
}
.patient-profiles .desk-callout {
    float: right;
    margin-right: 12px;
}
.combi-patient-profile .pgend-navigator.container-center {
    margin-top: 28px;
}
.mono-patient-profile .pgend-navigator.container-center {
    margin-top: 37px;
}    
.flag-txt h1{
    margin: 0;
    font-size: 16px;
    line-height: 20px;
}    
.monotherapy.profound-efficacy .magenta_eyebrow h1 {
    font-size: 20px;
    line-height: 24px;
    padding-top: 36px;
    padding-left: 15px;
    padding-right: 40px;
} 
span.regular-font {
     font-family: 'Roboto-BoldItalic' !important;

}

h1.container-center.pr-p3 {
    font-size: 24px!important;
    /*font-family: "Roboto-Bold" !important;*/
    font-family: 'Roboto-BlackItalic' !important;
    line-height: 30px!important;
}
.hrrm-testing h1.container-center {
    line-height: 30px;
    font-size: 24px;  
    margin-top: 5px;
    letter-spacing: 0.5px;
}
.hrrm-testing h1.container-center sup{
    position: relative;
    top: -10px;
    left: 0px;
}
.monotherapy.safety-tolerability h1.container-center{
	font-size: 28px;
    line-height: 38px;
    margin-top: 5px;
}
h1.container-center.safty-fnt {
    font-size: 24px!important;
    line-height: 30px!important;
    margin-top: 0px!important;
}
.pink_eyebrow.pink_eyebrow_nw h1.container-center {
    font-size: 24px;
    line-height: 30px;
    margin-top: 0px;
}
.brca-logo-m{
	padding-bottom: 0 !important;
}    
.desk-callout-inner p{
	font-family: "Roboto-Bold";
    line-height: 27px;
}    
.mechanism-of-action .propel-content .btn-banner a:after {
    right: -12px !important;
}    
.patient-profiles .william-opt p, .patient-profiles .joe-opt p{
	font-size: 16px;
}
.now-approve p{
	margin-bottom: 0;
}
.homepg-callout{
	float: none;
    margin: 4.5% auto 0;
}
span.dis-inline {
    display: inline-block;
}
.homepg-callout.desk-callout{
	display: none; 
}
.homepg-callout.desk-callout.desk-callout-left.desk-callout-lefts2 {
    display: block!important;
}
.homepg-callout.desk-callout.desk-callout-left.desk-callout-lefts2 p{
    padding: 2px 0px 3px;
}

.combi-patient-profile .desk-callout-but .ar-right:after {
    right: -66px;
}
.homepg-callout.desk-callout.desk-callout-left {
    margin: 4.5% 5% 0 0;
    float: right;
    max-width: 281px;
}
.trate-path-head {
    font-size: 20px;
    line-height: 24px;
    text-align: left;
    margin-bottom: 26px;
}
p.treat-studytxt {
    font-size: 16px;
    line-height: 20px;
    margin-bottom: 32px;
}
p.treat-disclaimer {
    font-size: 16px;
    line-height: 20px;
    margin-bottom: 24px;
    margin-top: 18px;
}
.mobile.treatpath-diagram{
	margin: 0 auto;
    display: block !important;
    max-width: 336px;
    text-align: center;
}
.william-opt.william-opt-new {
   width: 86%;
    margin-left: 26px;
    margin-top: 24px;
    padding: 0px;
    margin-bottom: 55px;
}
.william-opt.william-opt-new p {
font-size: 16px!important;
    line-height: 20px!important;
    text-align: center!important;
    padding-left: 45px!important;
    padding-right: 44px!important;
}

.patient-profiles .patient-profile-wrap{
	background: #004D7412;
    overflow: hidden;
    padding: 38px 0;
}
.patient-profiles .combi-patient-profile .patient-profile-wrap {
    padding-top: 13px;
}
.patient-profiles .pat-detail .curr-age br{
	display: block;
}
.patient-profiles .pat-detail .curr-age{
	margin-left: 0;
    margin-top: 20px;
    line-height: 30px;
}
.patient-profiles .pat-detail .curr-age span.nowrap {
    line-height: 30px;
}
.patient-profiles p.curr-age {
    font-size: 25px;
    line-height: 35px;
}
.patient-profiles .pat-detail h4{
	font-size: 22px;
    /*margin-left: -10px;*/
    letter-spacing: -0.55px;
}
.patient-profiles .pat-detail h4.second{
    padding-right: 70px;
}
.patient-profiles .william-opt, 
.patient-profiles .joe-opt{
	background-color: #801852;
}
.joe-opt.joe-optss {
    padding: 9px 51px 8px 45px!important;
}
.patient-profiles .william-opt p, 
.patient-profiles .joe-opt p{
	color: #FFFFFF;
}
.patient-profiles .propel-content .btn-banner{
	margin-top: 50px;
}
.patient-profiles .combi-patient-profile .patient-profile-wrap h4{
	    font-size: 22px;
    line-height: 26px;
    margin-bottom: 30px;
}
.patient-profiles .combi-patient-profile .medical-hist.mobile .container-center,
.patient-profiles .combi-patient-profile .medical-hist.mobile{
	padding: 4px !important;
}
.patient-profiles .combi-patient-profile .med-facts,
.patient-profiles .combi-patient-profile .joe-history{
	padding-right:0;
}
.patient-profiles .combi-patient-profile .med-facts li {
    padding-bottom: 8px;
}
.patient-profiles .combi-patient-profile p.fact-head {
    margin-bottom: 8px;
    margin-top: 15px;
        font-size: 20px;
}
.patient-profiles .combi-patient-profile .med-facts p{
	margin: 0;
}
.patient-profiles .med-facts ul{
	margin-bottom: 0;
}
.medical-hist.mobile.col-xs-12.col-sm-6 .joe-history .med-facts ul {
    text-indent: -6px;
}

.medical-hist.mobile.col-xs-12.col-sm-6 .joe-history .med-facts ul li {
    line-height: 18px;
}

.medical-hist.mobile.col-xs-12.col-sm-6 .joe-history .med-facts p {
    line-height: 24px;
}




.patient-profiles .combi-patient-profile .skew-maroon-head.mobile {
    margin-top: 24px;
	padding: 5px 30px;
}

.patient-profiles .combi-patient-profile .skew-maroon-head{
	padding: 5px 42px;
        position: relative;
    left: -12px;
}
.patient-profiles .combi-patient-profile .med-facts{
	padding-left: 18px;
}
.patient-profiles .combi-patient-profile ul.profile-cont {
    padding-left: 10px;
}
.patient-profiles #maincontent .container-center {
    padding: 0 16px;
}
.patient-profiles .combi-patient-profile ul.profile-cont{
	line-height: 18px;
    font-size: 16px;        
}
.patient-profiles p.fact-head{
	font-size: 20px;
    line-height: 20px;
}
.patient-profiles .joe-history, .patient-profiles .william-history {
    padding: 0 0px 0 10px;
}
.patient-profiles .med-facts {
    padding: 0 4px 0 20px;
}
.patient-profiles .mono-patient-profile .med-facts li{
	padding-bottom: 5px;
}
.patient-profiles .mono-patient-profile .mobile.joe-history .med-facts li {
    line-height: 18px;
}
.patient-profiles .mono-patient-profile .mobile.joe-history .med-facts p {
    line-height: 18px;
}
.patient-profiles .mono-patient-profile p.fact-head{
	margin-bottom: 8px;
    padding-top: 5px;         
}
.patient-profiles .mono-patient-profile .joe-history > div {
    margin-bottom: 20px;
}
.patient-profiles #maincontent .patient-profile-wrap .container-center {
	padding: 0 8px 0 24px;
}

.patient-profiles .william-opt p, .patient-profiles .joe-opt p {

    text-align: center;
}
.joe-opt.joe-opt-new p {
    font-size: 16px;
    line-height: 20px;
    text-align: center;
    padding-left: 60px;
    padding-right: 65px;
}
.william-opt.william-opt-new p {
    font-size: 16px;
    line-height: 20px;
    text-align: left;
    padding-left: 72px;
    padding-right: 40px;
}
p.footnote.marginbottom20.abi-new.abi-new1 {
    color: #000!important;
}
.reference.container-center.ref-align {
    padding: 0 19px!important;
}
.safety-combination-theraphy .pink_eyebrow{
	padding-top: 45px;
    padding-bottom: 20px;
    padding-right: 26px;
}
.pad-left {
	margin-bottom: 5px;
}
.safety-combination-theraphy .pink_eyebrow h1.container-center{
	line-height: 30px;
    font-size: 24px;
    margin-top: 0px;
    padding-left: 0px;       
}
.safety-combination-theraphy .clinicalstudytxt{
	line-height: 24px;
}
.safety-combination-theraphy .footnote{
	font-size: 12px !important;
	line-height: 14px !important;
}
.safety-combination-theraphy .safetylistsect ul li{
	list-style-type: none;
       text-indent: -5px;         
}
.safety-combination-theraphy .safetylistsect ul li:before{
	content: "•";
    font-size: 16px;
    position: relative;
    left: -5px;
}
.combination-therapy.safety-tolerability.safety-combination-theraphy .footnote {
    text-indent: 0px;
}

.safety-combination-theraphy .safetylistsect ul{
	    line-height: 18px;
    font-size: 14px;
        padding-left: 35px;
}
.safety-combination-theraphy .propel-content .btn-banner a{
	letter-spacing: -0.24px;
}
.hrrm-testing .pink_eyebrow{
	padding-top: 45px;
    padding-bottom: 40px;
    padding-right: 10px;
}
.hrrm-testing .propel-box{
	max-width: 320px;
	font-size: 17px;
	line-height: 18px;
        margin-bottom: 28px;
        padding: 16px 0;
}
.hrrm-testing .bio-txt{
    font-size: 20px;
    line-height: 24px;
    text-align: left;
    margin-bottom: 30px;
}

.hrrm-testing .container-center.skew-maroon-box {
    max-width: 330px;
	font-size: 17px;
	line-height: 19px;
    margin: 30px auto;
    padding: 16px 0;
}
.hrrm-testing .why-test-sec .flex_container_brca.container-center{
	padding-top: 20px;
}
.hrrm-testing .chart-sec-head{
	font-size: 16px;
	line-height: 20px;
	margin-bottom: 18px;
}
.hrrm-testing .container28{
	max-width: 239px;
	margin: 0 auto 40px;
}
.hrrm-testing .whytest-flex{
	flex-direction: column;
        margin-top: 25px;
}
.hrrm-testing .mobile-only.stats-patients img{
	width: 100%;
}
.hrrm-testing .pink-bg {
    font-size: 35px;
    line-height: 46px;
    text-align: center;
}

.hrrm-testing .pinkhead-cont
.hrrm-testing .pink-head {
    font-size: 18px;
    line-height: 22px;
} 
.hrrm-testing .pink-head {
	padding: 10px 10px 0 10px;
}
.hrrm-testing .pinkhead-cont {
    padding: 0px 10px 17px 10px;
} 
.hrrm-testing .hrrm-foot-note p:first-child {
    font-size: 12px;
    line-height: 14px;
        text-indent: -5px;
}
.hrrm-testing .hrrm-foot-note p:last-child {
    font-size: 16px;
    line-height: 20px;
    text-indent: -7px;
        padding-bottom: 20px;
}
.hrrm-testing .section-two.how-and-when p {
    font-size: 20px;
    line-height: 24px;
}
.hrrm-testing .section-two.how-and-when h2 {
    font-size: 32px;
    line-height: 30px;
}
.hrrm-testing .propel-content .btn-banner{
	margin-right: 0;
}
.hrrm-testing .propel-content {
	margin-top: 50px;
	margin-bottom: 40px;
        width: 332px;
    margin-right: 0;
}
.sect-1 .heading-1{
    font-size: 20px;
    line-height: 24px;
    margin-bottom: 28px;
}
.img-desc{
	font-size: 16px;
    line-height: 20px;
}
.sect-1 .img-cont{
	margin-bottom: 38px;
        text-align: center;
}
.sect-2 .img-cont{
	margin-bottom: 24px;
}
.sect-3 .footnote {
    font-size: 16px !important;
    line-height: 20px !important;
    text-indent: -10px;
    padding-left: 12px;
} 
.sect-2 .img-desc{
	margin-bottom: 15px;
}

.moa-combi .moa-process{
	flex-direction: column;
}
.mechanism-of-action .propel-content .btn-banner{
    padding: 13px 24px 13px 6px;	
}
.mechanism-of-action section.propel-content{
	margin-top: 45px;
}
.moa-combi .sect-1 .heading-1{
	margin-bottom: 10px;
}

.mechanism-of-action .end-notes .footnotes {
    font-size: 12px;
	line-height: 14px;
	margin-bottom: 0px;
}
.mechanism-of-action .end-notes .footnotes:nth-child(2){
	margin-bottom: 10px;
}

.mechanism-of-action .propel-content .btn-banner{
    padding: 12px 3px 12px 3px;
    margin-top: 10px;
    width: 197px;
    height: 45px;
}
.mechanism-of-action section.propel-content{
	margin-top: 45px;
}
.mechanism-of-action .propel-content .btn-banner a{
	font-size: 18px;
    line-height: 20px;
	letter-spacing: -0.27px;
}
.mechanism-of-action .propel-content .btn-banner a {
    padding: 10px 12px 10px 12px;
}
.moa .moa-combi .sect-1 { padding : 0px 10px;}
.moa-combi .sect-1 .heading-1{
	margin-bottom: 24px;
}

.mechanism-of-action .common-head{
	font-size: 16px;
	line-height: 20px;
    margin-bottom: 10px;
}

.moa.mechanism-of-action main#maincontent {
    margin-top: 93px !important;
}

.mechanism-of-action .end-notes .footnotes:nth-child(1){
	margin-bottom: 10px;
}
.mechanism-of-action .end-notes {
    margin-bottom: 10px;
    margin-top: 10px;
}
.green-cont.theraphy-steps{
	max-width: 440px;
    width: 100%;
    padding: 20px 60px 37px 20px;
    height: 206px;
    font-size: 16px;
    line-height: 22px;
    position: relative;
    margin-bottom: -28px;
}

.grey-cont.theraphy-steps {
	max-width: 494px;
    width: 100%;
    padding: 30px 20px 35px 20px;
    height: 220px;
    font-size: 18px;
    position: relative;
    margin-top: -28px;
}
.green-cont.theraphy-steps .head,
.grey-cont.theraphy-steps .head{
 	font-size: 26px;
    line-height: 22px;
}
.grey-cont.theraphy-steps .head {
    /*line-height: 16px;*/
}
p.subhead-inner {
    line-height: 22px;
    font-size: 16px;
}
.green-cont.theraphy-steps .head span,
.grey-cont.theraphy-steps .head span{
 	font-size: 18px;
    line-height: 16px;
}
.grey-cont.theraphy-steps .head span{
	display: block;
}
ul.process-steps {
    padding-left: 18px;
}
ul.process-steps li{
	line-height: 18px;
    font-size: 16px;
}
ul.process-steps li:first-child{
	margin-bottom: 10px;
}
}  

@media (max-width: 360px){
   .safety-combination-theraphy .pink_eyebrow h1.container-center{
	line-height: 30px;
	font-size: 22px;
    margin-top: 5px;        
}
}

/***desktop nav code*****/
@media (min-width: 1004px){
.fullnavigation,
.fullnavigation .dropdown-menu.multi-level > li{
	    background-color: #990064;
}
li.dosing  ul.dropdown-menu.multi-level a{
	text-align: left;
}

.fullnavigation .navbar li.dosing ul.dropdown-menu li>a{ 
    font-family: 'Roboto-Regular';
    color: #FFFFFF;
    white-space: normal;
    text-align: left; 
}  
.fullnavigation .navbar li.dosing{
	position: relative;
}
.fullnavigation .navbar li.dosing ul.multi-level li:last-child{
    background: #FFFFFF !important;
    opacity: 0.95;
}
.fullnavigation .navbar li.dosing ul.multi-level .select-txt{
	border-radius: 0 0 10px 10px;
}
.fullnavigation .navbar li.dosing ul.multi-level li:last-child > a{
	color: #000000 !important;
}
.fullnavigation ul.dropdown-menu.multi-level li{
	max-width: 338px;
    width: 338px;
}
.fullnavigation .navbar li.safety-tolerability ul.multi-level li,
.fullnavigation .navbar li.safety-tolerability ul.multi-level li > a{
	max-width: 425px;
	xwidth: 425px;
}
.fullnavigation .navbar li.efficacy ul.multi-level li > a {
    max-width: 338px;
}
}


@media (min-width: 767px){
/**patient profile tabs***/
.patient-profiles .tab-head-container {
	max-width: 1004px;
	margin: 25px auto 32px;
        height: 76px;
}
.patient-profiles .tab-head-container .tabs-body{
    display: -webkit-box;
  display: -webkit-flex;
  display: -ms-flexbox;
	display: flex;
	justify-content: space-between;
        transform: skewX(10deg);
}
.patient-profiles.tab-links {
	margin-top: 24px;
}
.patient-profiles .container-center.thumbnail .col-sm-4{
	width: 31.5%;
}
.patient-profiles .tab-head-container .tab-heading h1{
	margin-top: 10px;
        line-height: 35px;
}

/**NCCN profile tabs***/
.nccn-guidelines .tab-head-container {
	max-width: 1004px;
	margin: 25px auto 32px;
        height: 76px;
}
.nccn-guidelines .tab-head-container .tabs-body{
    display: -webkit-box;
  display: -webkit-flex;
  display: -ms-flexbox;
	display: flex;
	justify-content: space-between;
        transform: skewX(10deg);
}
.nccn-guidelines.tab-links {
	margin-top: 24px;
}
.nccn-guidelines .container-center.thumbnail .col-sm-4{
	width: 31.5%;
}
.nccn-guidelines .tab-head-container .tab-heading h1{
	margin-top: 10px;
        line-height: 35px;
}

}

@media (max-width: 1003px){
.patient-profiles .tab-head-container {
	margin-top: 0;
    margin-bottom: 25px;
}

}

@media (min-width: 992px){
.patient-profiles .desk-callout{
	/*margin-right: 30px; */
    margin-right: 20px;
}    
.combi-patient-profile .pgend-navigator.container-center {
    margin-top: 32px;
}
.mono-patient-profile .desk-callout.deskcallout-second {
    margin-top: 30px;
}   
.monotherapy.safety-tolerability h1.container-center{
	font-size: 30px;
    margin-top: 5px;
}    
.patient-profiles .combi-patient-profile .med-facts li{
	text-indent: -5px;
}    
.trate-path-head{
	font-size: 25px;
	line-height: 28px;
	text-align: left;
    margin-bottom: 32px;  
    padding-right: 35px;
}
.desktop.treatpath-diagram{
	margin-bottom: 34px;
}
p.treat-studytxt{
	font-size: 20px;
    line-height: 18px;
    margin-bottom: 37px;
}
p.treat-disclaimer{
	font-size: 16px;
    line-height: 18px;
    margin-bottom: 20px;
}
.patient-profiles .combi-patient-profile .patient-profile-wrap h4{
	    font-size: 24px;
    line-height: 26px;
    margin-bottom: 22px;
}
.patient-profiles .combi-patient-profile .joe-history{
	height: 545px;
}
.patient-profiles .joe-history, 
.patient-profiles .william-history{
	height: 525px;
}

.patient-profiles .end-banner-patient{
	margin-top: 72px;
}
.patient-profiles .combi-patient-profile ul.profile-cont li{
	font-size: 20px;
    line-height: 24px;
    padding-bottom: 5px;
}
.skew-maroon-head.david-skew {
	max-width: 435px;
}
.skew-maroon-head.david-skew p{
	font-size: 18px;
    line-height: 23px;
    text-align: center;
    margin-bottom: 0;
	padding: 14px 12px;
        transform: skewX(10deg);
}
.safety-combination-theraphy .propel-content .btn-banner {
    max-width: 286px;
        padding: 11px 10px 11px 0;
    margin-top: 32px;
}
.safety-combination-theraphy .propel-content .btn-banner a{
	font-size: 18px;
    letter-spacing: -0.27px;
}
.safety-combination-theraphy .adverseImg img,
.safety-combination-theraphy .labimg img{
	max-width: 1012px;
    width: 1012px;
}

.safety-combination-theraphy .pink_eyebrow h1.container-center{
	line-height: 36px;
	/*letter-spacing: 0.9px;*/
        font-size: 30px;
    margin-top: 5px;  
    padding-left: 0px;
    padding-right: 0px;
}
.safety-combination-theraphy .footnote{
	font-size: 10px !important;
	line-height: 12px !important;
}
.safety-combination-theraphy .pink_eyebrow{
	padding-top: 67px;
    padding-bottom: 50px;
}
.hrrm-testing .propel-box{
	max-width: 456px;
	font-size: 25px;
	line-height: 28px;
        margin: 0 auto 60px;
}
.hrrm-testing .pink_eyebrow{
	padding-top: 48px;
    padding-bottom: 27px;

}
.pink_eyebrow.color-pulm {
    background: #990064 0% 0% no-repeat padding-box!important;
}
.pink_eyebrow.color-browns {
    background: #801852 0% 0% no-repeat padding-box;
}
.hrrm-testing .bio-txt{
    font-size: 25px;
    line-height: 28px;
    text-align: left;
    margin-bottom: 30px;
}

.hrrm-testing .container-center.skew-maroon-box {
    max-width: 480px;
	font-size: 25px;
	line-height: 28px;
    margin: 62px auto 70px;
    padding: 18px 0;
}
.hrrm-testing .why-test-sec .flex_container_brca.container-center{
	padding-top: 20px;
}
.hrrm-testing .container-center.skew-maroon-box {
    background: #990064;
}
.hrrm-testing .desktop.why-test-chart img{
	max-width: 677px;
}
.hrrm-testing .chart-sec-head{
	font-size: 20px;
	line-height: 14px;
    margin-bottom: 28px;
}
.hrrm-testing .container28{
	max-width: 239px;
    margin-right: 75px;
    margin-top: 40px;
    height: fit-content;
}
.hrrm-testing .pink-bg {
    font-size: 43px;
    line-height: 57px;
    text-align: center;
        padding: 8px 10px;
}

.hrrm-testing .pinkhead-cont,
.hrrm-testing .pink-head {
    font-size: 20px;
    line-height: 28px;
} 
.hrrm-testing .pink-head {
	padding: 10px 10px 0 10px;
}
.hrrm-testing .pinkhead-cont {
    padding: 0px 10px 17px 10px;
} 
.hrrm-testing .section-two.how-and-when p {
    font-size: 25px;
    line-height: 28px;
}
.hrrm-testing .section-two.how-and-when h2 {
    font-size: 36px;
    line-height: 30px;
    margin-bottom: 19px;
    margin-top: 7px;
}
.hrrm-testing .hrrm-foot-note p:first-child{
	font-size: 10px;
    line-height: 12px;
        text-indent: -5px;
}
.hrrm-testing .hrrm-foot-note p:last-child{
	font-size: 16px;
    line-height: 20px;
    text-indent: -7px;
}
.hrrm-testing .biopsywrap .wheretxt {
    font-size: 16px;
    line-height: 20px;
}
.wheretxt.wheretesting { margin: 15px 0px 25px 0; }
.hrrm-testing .section-three .footnotecontiner .footnote {
    line-height: 20px;
}
.hrrm-testing h1.container-center {
    max-width: 800px;
    margin-left: 168px;
        line-height: 36px;
        font-size: 30px;
    margin-top: 5px;    
}
.hrrm-testing h1.container-center sup{
    position: relative;
    top: -10px;
    left: 0px;
    font-size: 16px;
}
sup.spc-left {
    left: 3px!important;
}
.hrrm-testing .pageend-navigator{
	display: table;
}
.hrrm-testing .propel-content{
	width: 363px;
    display: table-cell;
}
.hrrm-testing .pageend-navigator{
    margin-top: 0px;
    position: relative;
    left: 110px;
}
.sect-1 .heading-1{
    font-size: 25px;
    line-height: 28px;
	margin-bottom: 30px;
}
.heading-1.heading-paddright {
    margin-right: -48px;
}
.img-desc{
	font-size: 16px;
    line-height: 20px;
	margin-bottom: 20px;
}

.moa-mono .img-cont{
	margin-bottom: 12px;
}
.img-cont{
	margin-bottom: 47px;
}
.sect-2 .img-cont{
	margin-bottom: 36px;
}
.sect-3 .footnote {
    font-size: 16px !important;
    line-height: 20px;
}
.mechanism-of-action .propel-content .btn-banner{
    padding: 12px 3px 12px 3px;
}
.mechanism-of-action section.propel-content{
	margin-top: 28px;
}
section.propel-content.propel-content-tp {
    margin-top: -19px!important;
}
.mechanism-of-action .propel-content .btn-banner a{
	font-size: 18px;
    line-height: 20px;
	letter-spacing: -0.27px;
}
.mechanism-of-action .propel-content .btn-banner a {
    padding: 10px 12px 10px 12px;
}
.moa-combi .sect-1 .heading-1{
	margin-bottom: 35px;
}
img.img-responsive.desktop.img-responsive-desktop1 {
    width: 961px;
}
.moa-combi .sect-1 .end-notes{
	margin-bottom: 35px;
}
.moa .moa-combi .sect-1 { margin-left: 8px; }
.moa .moa-combi .end-notes, .moa .moa-mono p.footnote:nth-child(2) { padding-left: 8px; }
.moa .moa-mono p.footnote:first-child { padding-left: 10px; }
.mechanism-of-action .common-head{
	font-size: 20px;
	line-height: 22px;
    margin-bottom: 50px;
}
.mechanism-of-action .end-notes .footnotes {
    font-size: 10px;
	line-height: 12px;
	margin-bottom: 0px;
}
.mechanism-of-action .end-notes .footnotes:nth-child(1){
	margin-bottom: 5px;
}
.mechanism-of-action .end-notes {
    margin-bottom: 10px;
    margin-top: 10px;
}
.green-cont.theraphy-steps{
	max-width: 440px;
    width: 100%;
    padding: 20px 40px 37px 25px;
    height: 178px;
    font-size: 18px;
    position: relative;
}
.grey-cont.theraphy-steps .subhead-inner,
.green-cont.theraphy-steps .subhead-inner{
	line-height: 22px;
}
.grey-cont.theraphy-steps {
	max-width: 494px;
    width: 100%;
    padding: 20px 12px 37px 10px;
    height: 178px;
    font-size: 18px;
    position: relative;
}
.green-cont.theraphy-steps .head,
.grey-cont.theraphy-steps .head{
 	font-size: 26px;
    line-height: 22px;
}
.green-cont.theraphy-steps .head span,
.grey-cont.theraphy-steps .head span{
 	font-size: 18px;
}
ul.process-steps {
    padding-left: 20px;
}
.green-cont.theraphy-steps:after{
	content: " ";
    position: absolute;
    display: block;
    width: 100%;
    height: 100%;
    top: 0;
    left: 10px;
    z-index: -1;
    background: #B2D234;
    transform-origin: bottom left;
    -ms-transform: skew(-30deg, 0deg);
    -webkit-transform: skew(-30deg, 0deg);
    transform: skew(-10deg, 0deg);
}
.grey-cont.theraphy-steps:after{
	content: " ";
    position: absolute;
    display: block;
    width: 100%;
    height: 100%;
    top: 0;
    left: -8px;
    z-index: -1;
    background: #56849F;
    transform-origin: top left;
    -ms-transform: skew(-30deg, 0deg);
    -webkit-transform: skew(-30deg, 0deg);
    transform: skew(-10deg, 0deg);
}
.hrrm-testing .propel-box{
	padding: 18px 12px;
}
.hrrm-testing .recommendImg img {
    margin-top: -5px;
}
.hrrm-testing .pageend-navigator .propel-content .btn-banner a{
    font-size: 18px;
    letter-spacing: -0.27px;
	padding-right: 28px !important;
}
.hrrm-testing .pageend-navigator .propel-content{
    width: 380px;
}
.hrrm-testing .propel-content .btn-banner a:after{
	right: 8px;
    top: 15px;
}
.grey-cont.theraphy-steps .process-steps li,
.green-cont.theraphy-steps .process-steps li{
	line-height: 22px;
    margin-bottom: 7px;
}



.patient-profiles .pageend-navigator .propel-content .btn-banner a{
        font-size: 18px;
    letter-spacing: -0.27px;
	    padding-right: 30px !important;
}
.patient-profiles .joe-history > div, .patient-profiles .william-history> div {
    position: relative;
    left: -10px;
}
.patient-profiles .william-history p.fact-head::before,
.patient-profiles .joe-history p.fact-head::before{
	left: -10px;
        top: 1.5px;
}
.patient-profiles p.fact-head{
	line-height: 20px;
}
.patient-profiles .medical-hist{
	margin-top: -40px;
}
.patient-profiles .patient-profile-wrap{
	padding-bottom: 20px;
        padding-top: 30px;
}
.patient-profiles .pat-detail .curr-age{
	line-height: 33px;
}
.patient-profiles .pat-detail .curr-age, 
.patient-profiles .pat-detail h4{
	line-height: 30px;
}
.patient-profiles .pageend-navigator .propel-content .btn-banner a{
        font-size: 18px;
    letter-spacing: -0.27px;
}
.patient-profiles .combi-patient-profile .pat-detail .curr-age{
	    line-height: 30px;
    margin-top: 25px;
    margin-bottom: 0;
}
.patient-profiles .combi-patient-profile p.fact-head {
    margin-bottom: 6px;
}

.patient-profiles .combi-patient-profile ul.profile-cont{
	padding-left: 12px;
}
    ul.profile-cont.profile-cont-font li {
    font-size: 16px!important;
    line-height: 18px!important;
}
.patient-profiles .combi-patient-profile .med-facts ul {
    padding-left: 35px;
}
.safety-combination-theraphy .platinum_chart{
	margin-top: 26px;
}
.safety-combination-theraphy .clinicalstudytxt {
    line-height: 28px;
        margin-top: 32px !important;
}
.safety-combination-theraphy .safetylistsect li{
    line-height: 20px;
}
.safety-combination-theraphy .platinum_chart{
	margin-bottom: 10px;
}
.safety-combination-theraphy .clinicalstudytxt:first-child{
	margin-top:25px;
}
.hrrm-testing .section-three{
	padding-bottom: 20px;
}
.combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic img:first-child{
	/*max-width: 148px;*/
        max-width: 183px;
}
.patient-profiles .mono-patient-profile .patient-profile-wrap{
	    padding-top: 50px;
        padding-bottom: 30px;
}
.patient-profiles .mono-patient-profile .propel-content .btn-banner{
	    margin-top: 50px;
}
}            




@media screen and (min-width: 768px) and (max-width: 991px) {
.home .approved-callout.mobile {
    margin-top: 4px;
}
.home .now-approve p {
        padding: 2px 10px 1px 10px;
}
.home .flag-txt {
        padding: 5px 10px;
}


.hrrm-testing .propel-box{
	margin-left: auto;
    margin-right: auto;
}
.safety-combination-theraphy .section-one .footnotecontiner{
    padding-left: 35px;
}
.patient-profiles .tab-head-container{
	height: 116px;
        width: 97%;                            
}
.patient-profiles .tab-heading {
    max-width: 300px;
}    
.patient-profiles #tab-opener-2 > a{
	    max-width: 187px;
} 
.patient-profiles .tab-head-container .tabs-body   {
	align-items: center;
}   
.green-cont.theraphy-steps {
    max-width: 494px; 
        height: 220px;                                    
}
.propel-content .container-center .btn-banner a:after {
    right: 6px !important;
    top: 16px;                                        
}
.combi-therapy-content .img-box img:first-child{
	transform: none !important;
}
.propel-efficacy .propel-content.cont-2 .skew-maroon-head h2{
	padding: 4px 0px;
}
.propel-efficacy .propel-content .skew-maroon-head{
	padding-right: 20px;
}
.propel-content.cont-2 .skew-maroon-head {
    max-width: 340px !important;
}
.propel-efficacy .propel-content .skew-maroon-head.last-skew-maroon-head h2{
	    padding-top: 10px;
    padding-bottom: 10px;
}

.safety-combination-theraphy .pink_eyebrow{
	padding-bottom: 40px;
}
.tab-active, .video-library .tab-links>nav a.nav-item:active, 
.video-library .tab-links>nav a.nav-item:focus, 
.video-library .tab-links>nav a.nav-item:hover{
	border-bottom: none !important;
}
}                                    

@media only screen and (min-width: 605px) and (max-width: 992px){
.propel-efficacy img.img-responsive.mobile.os-kmcurve {
    display: block !important;
    width: 100%;
}
}

@media only screen and (min-width: 1024px) and (max-width: 1100px){
.home .landing-hero-image{
	    background-position-x: -100px !important;
}	
}
@media only screen and (min-width: 1139px) and (max-width: 1279px){
.home .landing-hero-image{
	    background-position-x: 0 !important;
}	
}

@media only screen and (min-width: 992px) and (max-width: 1100px){
.homepg-callout {
   margin: -7% 5% 0 0;
}
 .homepg-callout.desk-callout.desk-callout-left {
    margin: 4.5% 2% 0 0;
}
.combi-therapy-content .daily-dose-rec-container .dosage-body-flex{
	    flex-direction: row !important;
}   
.combi-therapy-content .dose-reduces {
    max-width: 578px !important;                            
}
.safety-combination-theraphy .adverseImg img, .safety-combination-theraphy .labimg img {
    max-width: 1012px;
    width: 982px;
}    
.patient-profiles .combi-patient-profile .joe-history {
    height: 655px;
}
}

                    
@media only screen and (min-width: 1024px) and (max-width: 1350px){
.home .approved-callout {
    top: -2px;
}
.home .landing-hero-image{
	height: 400px !important;
    /*background-position-x: -100px !important;*/
}
.patient-profiles .combi-patient-profile .joe-history {
    height: 670px;
}
.safety-combination-theraphy .desktop.adverse-react-head{
	left: 22px !important;
}
.hrrm-testing .hrrm-foot-note{
	    margin-left: 10px;
}
}

@media (min-width: 1024px) and (max-width: 1250px){
.patient-profiles .medical-hist {
    margin-top: -70px;
}
.footnote-below-landong {
    /* padding: 36px 0px 0px 461px; */
    padding: 36px 0px 0px 30px!important;
    margin-bottom: -49px;
}
}

@media (min-width: 1351px) {
.patient-profiles .combi-patient-profile .joe-history {
    /*height: 625px; */
    height: 510px;
}
}    

@media (min-width: 320px) and (max-width: 374px){
.pageend-navigator .propel-content{
    width: 290px;
}
.propel-content .btn-banner a{
	font-size: 14px !important;
}
.safety-combination-theraphy .clinicalstudytxt .nowrap:last-child {
    white-space: normal;
}
.patient-profiles #tab-opener-1 > a {
    /*padding: 10px 15px 10px;*/
    padding: 10px 3px 10px;
} 

span.i5-nowrap {
    white-space: nowrap;
}  
span.dis-inline {
    display: inline;
}

}    

@media only screen and (min-width: 992px) and (max-width: 1010px){
.hrrm-testing .pageend-navigator{
	left: 90px;
}

.hrrm-testing .biopsywrap .sectionleft, 
.hrrm-testing .biopsywrap .sectionright, 
.hrrm-testing .biopsywrap .middlecontent{
	width: 80%;
}
.hrrm-testing p.telephone-cont{
	clear: both;
}
}
@media only screen and (min-width: 1920px) and (max-width: 1920px){
h1.container-center.container-centers1 {
    margin-left: 439px;
    line-height: 36px;
    font-size: 30px;
    margin-top: 5px;
}
 .footnote-below-landong {
padding: 36px 0px 0px 461px!important;
   /* padding: 36px 0px 0px 185px;*/
    margin-bottom: -49px;
}   
}