@font-face {
    font-family: 'MyriadPro-Bold';
    src: url('fonts/myriadpro-bold.eot');
    src: url('fonts/myriadpro-bold.woff') format('woff'), url('fonts/myriadpro-bold.ttf') format('truetype');
    font-weight: normal;
    font-style: normal;
}

@font-face {
    font-family: 'MyriadPro-SemiBold';
    src: url('fonts/myriadpro-semibold.woff') format('woff');
    font-weight: normal;
    font-style: normal;
}
@font-face {
    font-family: 'Roboto-Black';
    src: url('/etc/designs/code/physician-services/US/lynparza-hcp-branded/fonts/newfont/Roboto-Black.woff') format('woff');
    font-weight: normal;
    font-style: normal;
    font-display: swap;
}
#test-pg-id {
    padding-top: 30px;
    font-size: 16px;
    font-family: 'Roboto-Regular';
    line-height: 20px;
    color: #000000;
}
.roboto-black-italic{
    font-family:'Roboto-BoldItalic';
    }
/* monotharpy*/
.sec66-rpfs {
	padding-left: 11px;
    text-indent: -5px;
    margin-bottom: 2px !important;
}
.sec66-rpfs li {
    font-family: 'Roboto-Regular';
    font-size: 14px;
}
.sec66-rpfs .first-li span {
    font-family: 'Roboto-Bold';
}
.sec66-patient, .sec66-patient2 {
    font-family: 'Roboto-Regular';
    font-size: 14px;
    margin-bottom: 0px;                
}
.sec31-rpfs {
	padding-left: 20px;
    padding-top: 20px;
    text-indent: -5px;
}
.monotherapy3 .sec31-rpfs {
   /* padding-left: 11px;*/
     padding-left: 15px;
}

/*.monotherapy3 .container-center.skew-maroon-head.skew-maroon-head-wdt.skew-maroon-head-wdt-h2 {
    padding-right: 190px!important;
    left: -42px!important;
}*/
.sec31-rpfs li, #sec31-patient{
	font-family: 'Roboto-Regular';
    font-size: 16px;
    color: #333333;
    padding-right: 19px;
    letter-spacing: 0.5px;
    line-height: 20px;
}
#sec31-patient{
	padding-left: 20px;
}
.monotherapy3 #sec31-patient{
	padding-left: 15px;
}
.sec31-rpfs li::marker {
  	color: #801852;
}
.pink78 {
	position: relative;
    left: -159px !important;
                    }
.monotherapy3 .pink78 {
	position: relative;
    left: -120px !important;
                    }
.pink78 h2{
    padding-right: 150px;
    margin-top: 4px !important;
    margin-bottom: 6px !important;                  
}
.pink78-pg {
	font-size: 25px;
    font-family: 'Roboto-Bold';
    color: #801852;
}
span.line-break {
    display: block;
}
.last78-pg {
	font-size : 14px;
    font-family: 'Roboto-Bold';
}
.monotherapy3 .last78-pg {
    font-size : 16px;
   
}
p.last78-pg {
    color: #333333;
}
.section31 {
	left: -60px !important;
}
.monotherapy3 .section31 {
	left: 15px !important;
}
.pink39-pg {
	font-size: 25px;
    font-family: 'Roboto-Bold';
    padding-left: 10px;
    color: #004D74;
}
p.pink39-pg.pink39-pg39 {
    padding-top: 9px;
    padding-bottom: 21px;
}


/* monotharpy*/
.mobile-show, .rpfs-footn-mobile {
	display: none;
}
.rpfs-p {
    padding-top: 17px;
    text-indent: 0px;
    margin-bottom: 0px;
    line-height: 14px!important;
        font-size: 10px;
    }
.rpfs-footn {
    line-height: 14px!important;
        font-size: 10px;
}

.propel-content .end-eff-cont .footnote{
	font-size: 10px !important;
	line-height: 12px !important;
}
.propel-content .end-eff-cont .footnote:nth-child(3){
	padding-bottom: 15px;
}
.propel-content .end-eff-cont .footnote:nth-child(4){
	text-indent: 0;
}                            
p.events-txt {
    padding-bottom: 15px;
}                            
.events-txt span{
	font-family: 'Roboto-Bold';
	color: #004d74;
}
.end-eff-cont-pg { font-family: 'Roboto-Bold'; padding-right: 40px;}
.propel-efficacy p.sub-head {
	    font-family: 'MyriadPro-Bold';
    font-size: 25px;
    line-height: 16px;
    color: #004D74;    
}
.skew-maroon-head.last-skew-maroon-head {
    margin-bottom: 40px !important;
}
.propel-efficacy .btm-txt .subnote span {
    font-family: 'Roboto-Bold' !important;
    color: #000000;
}
.no-italic {
    font-style: normal;
    padding-left: 2px;
}
.nccn-guidelines .footnotes p:last-child {
    /*text-indent: -4px;*/
    text-indent: -7px;
}
.nccn-mono .footnotes p:first-child{ text-indent: 0px; font-family: 'MyriadPro-Regular';}
.nccn-mono .footnotes p {
    text-indent: -4px;
}
.footnotes.tabs_desktop.tabs_desktop-left p {
    margin-left: -11px;
}
.indent{
    /*text-indent: -11px!important;*/
    text-indent: 0px!important;
}
.nccn-mono .nccn-rec{
	/*background: #D5E7F5;*/
    background: #eaf3fa;
}
p.indent.para1, .para3, .para4 {
    padding-bottom: 2px;
}
em.dis {
    display: inline-block;
}

.nccn-guidelines  .heading-1 .heading-sub{
	font-size: 20px;
    line-height: 28px;
    text-align: left;
    display: block;
}
.nccn-rec {
    /*background: #E8F1CF;*/
    background: #f3f8e7;
    /*padding: 35px 62px;*/
    /*transform: skewX(-5deg);*/
    transform: skewX(-6deg);
        margin-bottom: 16px;
}
.nccn-rec.tabs_desktop {    margin-left: 5px;}
.nccn-guidelines .tab-head-container .tab-heading h1 sup {
    font-style: normal;
}
.nccn-inner{
    transform: skewX(5deg);
    display: flex;
    justify-content: center;
    align-items: center;
}

.nccn-inner .images-sec {
    width: 100%;
    max-width: 223px;
    height: 215px;
    background: #E8F1CF!important;
    padding-top: 83px;
    padding-left: 48px;
    font-family: 'MyriadPro-Bold';
    font-style: italic;
    color: #004D74;
    font-size: 44px;
    line-height: 25px;
    transform: skewX(-5deg);
}
.image-sec.image-second{
      width: 100%;
    max-width: 263px;
    height: 308px;
    background: #d7e8f6!important;
    padding-top: 130px;
    padding-left: 22px;
    font-family: 'MyriadPro-Bold';
    font-style: italic;
    color: #004D74;
    font-size: 44px;
    line-height: 25px;
    transform: skewX(-5deg);
    text-align: center;
    }

.images-second span {
    font-size: 26px;
    display: block;
    margin-top: 8px;
}
.nccn-inner .images-sec span {
    font-size: 26px;
    display: block;
    margin-top: 8px;
}
.image-sec.image-second span {
    font-size: 26px;
    display: block;
    margin-top: 8px;
}
span.bold.font-size {
    font-size: 16px;
}
p.footnote.font-size1 {
    font-size: 10px;
}
p.color-brown {
    font-size: 20px!important;
    color: #801852!important;
    font-family: 'Roboto-Bold'!important;
}
p.color-brown25, p.color-brown31 {
    font-size: 25px!important;
    color: #801852!important;
    font-family: 'Roboto-Bold'!important;
    margin-bottom: 0px;
}
.Primary_endpoint-text-blue{
	font-size: 25px!important;
    font-family: 'Roboto-Regular';
    color: #004D74;
}
.Primary_endpoint-text-blue31 {
	font-size: 25px!important;
    font-family: 'Roboto-Bold'!important;
    color: #004D74;
	padding-top: 12px;
    line-height: 28px !important;
}
.spc{padding-left:5px;}
.content-right p {
    margin-bottom: 5px;
}
.line-h{
line-height:0px!important;
}
.sec71bg {width: 94%!important;}

p.explor-subg {
	color: #FFFFFF;
    font-family: 'Roboto-Bold';
    font-size: 20px;
    margin-left: -7px;
    margin-bottom: 0px;
    margin-top: 10px;
    transform: skew(11deg);
}


p.recommend_based.font-size {
    font-family: 'Roboto-Regular'!important;
    font-size: 18px!important;
}
.footnotes p {
    color: #333333;
    font-size: 9px;
    line-height: 11px;
    margin-bottom: 0;
}

.nccn-mono.container-center {
    display: none;
}
.image-sec {
    flex-basis: 40%;
    padding-right: 40px;
}
.image-second{

}
.footnotes.nccn-heads.fn-nccn-heads.fn-nccn-heads1 {
    display: none;
}
.nccn-head {
    font-size: 26px;
    line-height: 32px;
    font-family: 'MyriadPro-Bold' !important;
    color:#004D74;
    letter-spacing: -0.39px;
}
.nccn-head.nccn-heads {letter-spacing: 0px;}
.nccn-heads{
  padding-left: 33px;
}
.nccn-txt {
    font-size: 18px;
    line-height: 23px;
    color: #333333;
    font-family: 'MyriadPro-Regular'
}
p.nccn-txt.nccn-txtt1 {
    padding-right: 25px;
}

.padding-top-footnote {
    padding-top: 15px;
}
.cont-3.propel-content .margintop10.ipadp-mtop20 .footnote:last-child {
    margin-top: 20px;
        text-indent: 0;
}
.mb-0 {
    margin-bottom: 0 !important;
}
.mb-20{
	margin-bottom: 20px !important;
}
.dosing-callouts .dose-reduces .dose-red-body .tab-descript{
	font-size: 12px !important;
    padding-bottom: 10px;
    font-family: 'Roboto-Regular' !important;
}
section.propel-content.sec-2.bg-yellow.cont-4{
	padding-bottom: 15px;
}
.iit-txt{
	margin-bottom: 20px;
    text-align: left;
}   
span.normal-txt {
    font-family: 'Roboto-Regular';
}
.combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic p.sub-head {
    font-family: 'Roboto-Bold' !important;
}
.safety-combination-theraphy #footer .footnote{
		font-size: 16px !important;
		line-height: 20px !important;
	}
.mechanism-of-action .reference  em:nth-child(8) {
    padding-right: 3px;
}
/**moa tabs**/

.mono-foots,
.mechanism-of-action .moa-mono {
    display: none;
}

.mechanism-of-action .tab-head-container {
    background: #990064;
    transform: skewX(170deg);
    margin-top: 25px;
    margin-bottom: 35px;
    padding: 14px 28px 10px;
}

.mechanism-of-action .tab-links>nav>.nav-tabs {
    border: none;
}

.mechanism-of-action .tab-links .link-parent {
    display: inline-block;
    transform: skewX(170deg);
}

.mechanism-of-action .tab-active,
.mechanism-of-action .tab-links>nav a.nav-item:active,
.mechanism-of-action .tab-links>nav a.nav-item:focus,
.mechanism-of-action .tab-links>nav a.nav-item:hover {
    background-color: #FFFFFF !important;
    color: #990064 !important;
}

.mechanism-of-action #tab-opener-2>a {
    padding: 9px 30px 13px;
    display: inline-block;
    max-width: 197px;
    text-align: center;
}

.mechanism-of-action #tab-opener-1>a {
    /*padding: 9px 12px 13px;*/
    padding: 9px 11px 13px;
    display: inline-block;
    max-width: 197px;
    text-align: center;
}

.mechanism-of-action .tab-pane.active.in {
    display: block !important;
}

.mechanism-of-action .tab-pane.fade {
    display: none;
}

.mechanism-of-action .tab-head-container .tabs-body {
    display: flex;
    display: -webkit-box;
    display: -webkit-flex;
    display: -ms-flexbox;
}

.mechanism-of-action .tab-head-container .tab-heading h1 {
    font-size: 30px;
    line-height: 36px;
    font-family: 'Roboto-Bold';
    font-style: italic;
    color: #FFFFFF;
}

.mechanism-of-action .tab-links>nav a.nav-item {
    padding: 20px 30px 15px;
    color: #99006475;
    font-family: 'Roboto-Bold';
    font-size: 18px;
    background-color: #E3C8D7;
    text-decoration: none;
    line-height: 20px;
}


/**moa tabs**/

.foot_txt {
    margin-top: 10px;
}

.foot_txt p {
    font-size: 16px !important;
    line-height: 20px !important;
    color: #004D74;
}

.combi-therapy-header .solo-heading h1 {
    font-size: 30px !important;
    line-height: 36px !important;
    /*max-width: 775px;*/
    max-width: 925px;
}

.combi-therapy-header .solo-heading h1 sup {
    position: relative !important;
    top: -12px !important;
    left: 1px !important;
    padding-bottom: 9px;
}

.combi-therapy-content .heading p {
    font-family: 'Roboto-Bold' !important;
    color: #004D74;
    font-size: 25px !important;
    line-height: 28px !important;
    margin: 5px 0 20px 0;
}

.combi-therapy-content .daily-dose-rec-container .dosage-body-flex {
    background-color: transparent;
    padding: 4px 0;
    display: flex;
    flex-direction: row;
    justify-content: center;
    position: relative;
}

.combi-therapy-content .plus-img {
    position: absolute;
    top: 48%;
    left: 402px;
    transform: translateY(-50%);
}

.combi-therapy-content .daily-dose-rec-container .dosage-body-flex .recomended-dose-txt {
    background-color: #B2D234;
    text-align: left;
    padding: 30px;
    padding-right: 90px;
    transform: skewX(170deg);
}
img.img-responsive.img-responsive-width {
    width: 173px;
}
.combi-therapy-content .daily-dose-rec-container .dosage-body-flex .recomended-dose-txt p {
    text-align: left;
    font-size: 16px !important;
    line-height: 20px !important;
    margin-bottom: 10px;
    padding: 0 14px;
    transform: skewX(-170deg);
    color: #004D74;
}

.combi-therapy-content .daily-dose-rec-container .dosage-body-flex .recomended-dose-txt p.sub-head {
    font-size: 23px !important;
    line-height: 18px !important;
    margin-bottom: 10px;
    padding-left: 5px;
    font-family: 'Roboto-Bold' !important;
}

.combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic {
    background-color: #56849F;
    text-align: left;
    padding: 30px;
    padding-right: 50px;
    transform: skewX(170deg);
    display: flex;
    align-items: center;
}

.combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic p {
    text-align: left;
    font-size: 16px !important;
    line-height: 20px !important;
    margin-bottom: 15px;
    padding: 0 10px;
    transform: skewX(-170deg);
    color: #fff;
}

.combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic p:last-child {
    padding-left: 24px;
}

.combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic p.sub-head {
    font-size: 23px !important;
    line-height: 25px !important;
    margin-bottom: 10px;
    padding-left: 5px;
}

.combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic p:nth-child(4) {
    padding-left: 18px;
}

.combi-therapy-content .img-text {
    display: flex;
    justify-content: center;
    align-items: end;
    transform: skewX(-170deg);
}

.combi-therapy-content .img-text span {
    font-size: 23px;
    line-height: 30px;
    color: #004D74;
    font-family: 'Roboto-Bold' !important;
    font-style: italic;
    margin-left: 8px;
}

.combi-therapy-content div.divider {
    font-size: 18px;
    line-height: 22px;
    color: #fff;
    font-family: "Roboto-Bold";
    font-style: italic;
    margin-bottom: 12px;
    text-align: left;
   /* margin-left: 35%;*/
        margin-left: 29%;

}

.combi-therapy-content div.divider span {
    position: relative;
}

.combi-therapy-content div.divider span::before {
    content: '';
    position: absolute;
    border-bottom: 1px solid #fff;
    display: block;
    width: 34px;
    top: 50%;
    left: -48px;
}

.combi-therapy-content div.divider span::after {
    content: '';
    position: absolute;
    border-bottom: 1px solid #fff;
    display: block;
    width: 34px;
    top: 50%;
    right: -50px;
}

.combi-therapy-content .img-box {
    display: flex;
    flex-direction: column;
    justify-content: center;
    align-items: center;
    transform: skewX(-170deg);
        margin-top: -18px;
}

.combi-therapy-content .img-box span {
    font-size: 23px;
    line-height: 32px;
    color: #fff;
    font-family: "Roboto-Bold";
    font-style: italic;
    margin-left: 0;
}

.combi-therapy-content .text-box {
    width: 100%;
}

.combi-therapy-content .mgmt-options-container .mgmt-opt-flex {
    display: flex;
}

.combi-therapy-content .mgmt-head {
    background-color: #B2D234;
    transform: skewX(170deg);
    margin-left: 3px;
    margin-bottom: 2px;
    margin-right: -3px;
}

.combi-therapy-content .mgmt-options-container .mgmt-opt-flex p {
    font-family: 'MyriadPro-Bold' !important;
    color: #004D74;
    font-size: 18px !important;
    line-height: 28px !important;
}

.combi-therapy-content .mgmt-head>p {
    font-family: 'Roboto-Bold' !important;
    color: #004D74;
    transform: skewX(10deg);
    text-align: center;
}

.combi-therapy-content .dose-interrupts .dose-int-body,
.combi-therapy-content .dose-reduces .dose-red-body {
    background-color: #E8F1CF80;
    min-height: 288px;
}

.combi-therapy-content .mgmt-options-container p,
.combi-therapy-content .or-connect span {
    font-family: 'Roboto-Bold' !important;
    color: #004D74;
}

.combi-therapy-content .mgmt-options-container .init-reduce,
.combi-therapy-content .mgmt-options-container .final-reduce {
    display: flex;
    flex-direction: column;
    align-items: center;
    background: #e3efba;
    margin-bottom: 15px;
    max-width: 85%;
    margin: 0 auto;
    transform: skewX(170deg);
}

.combi-therapy-content .mgmt-options-container .init-reduce p,
.combi-therapy-content .mgmt-options-container .final-reduce p,
.combi-therapy-content .mgmt-options-container .init-reduce .img_box,
.combi-therapy-content .mgmt-options-container .final-reduce .img_box {
    transform: skewX(-170deg);
}

.combi-therapy-content .dosing-callouts {
    background-color: #FFFFFF;
}

.dosing-combination #maincontent .combi-therapy-content .dosing-callouts .or p {
    margin-top: 15px;
    font-size: 16px;
    line-height: 14px;
    color: #333;
    font-family: "Roboto-Bold";
    margin-bottom: 30px;
}

.combi-therapy-content .mgmt-options-container .init-reduce .img_box,
.combi-therapy-content .mgmt-options-container .final-reduce .img_box {
    display: flex;
    align-items: center;
    margin-bottom: 14px;
}

.combi-therapy-content .mgmt-options-container .init-reduce .img_box span,
.combi-therapy-content .mgmt-options-container .final-reduce .img_box span {
    font-size: 12px;
    line-height: 16px;
    color: #333;
    font-weight: 600;
    font-family: 'MyriadPro-Bold' !important;
    margin-right: 20px;
}

.combi-therapy-content .mgmt-options-container .dose-red-body p {
    font-size: 16px !important;
    line-height: 16px !important;
    color: #333;
    margin-bottom: 18px;
}

.combi-therapy-content .bg-heading {
    background: #8018521A;
    transform: skewX(170deg);
    display: flex;
    justify-content: center;
    align-items: center;
    margin-bottom: 3px;
    margin-left: 10px;
    padding: 10px 0 10px 0;
}

.combi-therapy-content .bg-heading p {}

.combi-therapy-content .bg-heading p {
    font-size: 20px !important;
    line-height: 19px !important;
    color: #333;
    transform: skewX(-170deg);
    text-align: center;
    margin: 0;
    font-family: 'MyriadPro-SemiBold' !important;
}

.dosing-combination #maincontent .combi-therapy-content .dose-discontinuation .dose-discontinuation-body p {
    color: #004d74;
    font-size: 16px !important;
    margin-top: 15px;
    line-height: 20px !important;
    padding: 0;
}

.combi-therapy-content .txt-banner {
    background: #9A0064;
    padding: 20px 52px;
    max-width: 820px;
    width: 100%;
    margin: 0 auto;
    margin-top: 45px;
    transform: skewX(175deg);
    box-shadow: 10px 10px 0px 1px #b2d234;
}

.dosing-combination #maincontent .combi-therapy-content .dose-discontinuation .dose-discontinuation-body .txt-banner p {
    font-family: "Roboto-Bold";
    font-size: 20px !important;
    line-height: 24px !important;
    color: #fff;
    transform: skewX(-175deg);
    font-style: italic;
    margin: 0;
    text-align: center;
}

.combi-therapy-content .btn-banner {
    background-color: #D8EA00;
    position: relative;
}

.combi-therapy-content .btn-banner {
    background-color: #990064;
    position: relative;
    transform: skewX(170deg);
    padding: 12px 10px 12px 0;
    float: right;
    margin-top: 50px;
        height: 45px;
}
.skew-maroon-head-new.skew-maroon-head-new-top {
    margin-top: 59px;
}
.combination-therapy.dosing-combination.dosing-combination .btn-banner {
    margin-top: 60px;
}

.combi-therapy-content .btn-banner a {
    font-size: 16px;
    line-height: 20px;
    position: relative;
    text-align: left;
    font-family: "Roboto-Bold";
    color: #fff;
    padding-right: 46px !important;
}

.combi-therapy-content .btn-banner a:after {
    content: " ";
    width: 12px;
    height: 13px;
    border: 3.5px solid #ffffff;
    position: absolute;
    right: 12px;
    top: 17px;
    transform: rotate(132deg);
    border-bottom: none;
    border-right: none;
}

.combi-therapy-content .btn-banner a:hover {
    text-decoration: none;
}

.combi-therapy-content table.table.table-dose-mod td {
    font-size: 14px;
    line-height: 20px;
    font-family: "Roboto-Regular";
    vertical-align: middle;
    padding: 12px;
    border-bottom: 1px solid #4a4a4a;
    border-top: none;
    border-left: 1px solid #4a4a4a;
    color: #333;
}

.combi-therapy-content table.table.table-dose-mod td:first-child {
    width: 36% !important;
    border-left: none;
}

.combi-therapy-content table.table.table-dose-mod td:nth-child(2) {
    width: 27% !important;
    text-align: center;
    background: #f7faea;
    color: #004D74;
}

.combi-therapy-content table.table.table-dose-mod td:nth-child(3) {
    width: 31% !important;
    text-align: center;
    background: #e6ecf0;
    color: #56849f;
}

.combi-therapy-content table.table.table-dose-mod td.white-head {
    padding: 4px 12px;
}

.combi-therapy-content table.table.table-dose-mod td.green-head {
    background: #b2d234;
    border-left: none;
    font-family: "Roboto-Bold";
    padding: 8px 12px;
    transform: skewX(170deg);
    position: relative;
    left: 4px;
}

.combi-therapy-content table.table.table-dose-mod td.green-head span {
    display: block;
    margin: 0 auto;
    transform: skewX(-170deg);
    line-height: 15px;
}

.combi-therapy-content table.table.table-dose-mod td.grey-head {
    background: #56849f;
    border-left: none;
    color: #fff;
    font-family: "Roboto-Bold";
    padding: 8px 12px;
    transform: skewX(170deg);
    position: relative;
    left: 4px;
}

.combi-therapy-content table.table.table-dose-mod td.grey-head span {
    display: block;
    margin: 0 auto;
    transform: skewX(-170deg);
    line-height: 15px;
}

.combi-therapy-header .solo-heading p {
    font-size: 20px;
    line-height: 32px;
    color: #fff;
    font-style: italic;
    font-family: 'Roboto-Bold';
}

.combi-therapy-header .common-headline {
    background: #990064;
}

section.propel-content {
    max-width: 1024px;
    margin: 0 auto;
}

.propel-content .skew-maroon-head {
    background-color: #990064;
    padding: 5px 35px;
    padding-right: 98px;
    transform: skewX(170deg);
    margin: 10px auto 28px;
    margin-left: 8px;
    width: fit-content;
    box-shadow: 10px 10px 0px 1px #b2d234;
}

.propel-content .skew-maroon-head h2 {
    color: #ffffff;
    margin: 10px 0;
    transform: skewX(10deg);
    font-size: 25px;
    line-height: 30px;
    font-family: "Roboto-Bold";
    padding-left: 0px;
}
.skew-maroon-head-new {
    background-color: #990064;
    padding: 1px 35px;
    transform: skewX(170deg);
    margin: 10px auto 28px;
    margin-left: 8px;
    width: fit-content;
}
.skew-maroon-head-new h2 {
        color: #ffffff;
    /*margin: 4px 0;*/
    margin: 4px -3px;
    transform: skewX(10deg);
    font-size: 14px;
    line-height: 25px;
    font-family: 'MyriadPro-Bold';
    padding-left: 0px;
    text-align: center;
}
.cont-4 .margintop20.ipadp-mtop20.paddingLeft5 {
    padding-left: 0;
}

.propel-content .heading p {
    font-family: 'Roboto-Bold' !important;
    color: #004D74;
    font-size: 25px !important;
    line-height: 28px !important;
    margin: 15px 0 15px 0;
    letter-spacing: 0;
}

.cont-3 .heading p {
    margin-top: 35px;
}

.propel-content .heading h5 {
    font-family: 'Roboto-Regular' !important;
    font-size: 16px !important;
    line-height: 20px !important;
    margin: 0 0 20px 0;
    color: #333333;
}

.propel-content .Primary_endpoint {
    margin: 30px auto 30px auto;
    overflow: auto;
} 
.img_sec {
    text-align: center;
}

.img_sec img.mobile {
    max-width: 500px;
    width: 100%;
}
.cont-1.propel-content .footnote{
    text-indent: -4px;
}
p.footnote.mobile.m1 {
    font-size: 12px!important;
    line-height: 14px!important;
}
p.footnote.mobile.m1:nth-child(2) {
    font-size: 14px !important;
    line-height: 16px !important;
}
.propel-content .footnote {
    color: #333333 !important;
    font-family: 'Roboto-Regular';
    /*font-size: 12px !important;
    line-height: 14px !important;*/
    font-size: 12px;
    line-height: 14px;
    margin-bottom: 2px;
	text-indent: -4px;
}

.propel-content .footnote.subnote {
    font-size: 16px !important;
    line-height: 20px !important;
        text-indent: 0;
}
.margintop10.ipadp-mtop20.font-10 p {
    font-size: 10px!important;
    line-height: 12px!important;
    padding-left: 7px;
}
.clr-blue {
    color: #004D74;
    ;
}

.pt-20 {
    padding-top: 20px;
}

.pb-20 {
    padding-bottom: 30px;
}

.heading.pink-skew {
    background: #9904641A;
    transform: skewX(-4deg);
    padding: 10px 10px 10px 20px;
    margin-top: 16px;
    margin-left: 8px;
    margin-right: 8px;
}

.heading.pink-skew h5.bold {
    text-indent: -10px;
    padding-left: 10px;
    margin-bottom: 4px;
    transform: skewX(4deg);
}

.heading.pink-skew h5.bold:first-child {
    padding-left: 7.5px;
}

p.sub-head {
    font-size: 20px;
    line-height: 16px;
    font-family: 'Roboto-Bold';
    color: #990064;
}

.btm-img {
    float: left;
    margin-right: 15px;
    margin-top: -5px;
}

.btm-txt {
    /* float: left;
    max-width: 90%; */
    margin-bottom: 25px;
}

.bg-yellow {
    background-color: #F8FFF7;
}

.propel-content .btn-banner {
    background-color: #990064;
    position: relative;
    transform: skewX(170deg);
    padding: 12px 10px 12px 0;
    float: right;
    /*margin-top: 40px;*/
    margin-top: 30px;
    margin-right: -10px;
}

.safety-tolerability .propel-content .btn-banner {
    padding: 11px 10px 12px 0;
}

.propel-content .btn-banner a {
    font-size: 16px;
    line-height: 20px;
    position: relative;
    text-align: left;
    font-family: "Roboto-Bold";
    color: #fff;
    padding-right: 38px !important;
    letter-spacing: -0.24px;
}

.propel-content .btn-banner a:hover {
    text-decoration: none;
}

.propel-content .btn-banner a:after {
    content: " ";
    width: 12px;
    height: 13px;
    border: 3.5px solid #ffffff;
    position: absolute;
    right: 7px;
    top: 13px;
    transform: rotate(132deg);
    border-bottom: none;
    border-right: none;
}

.combi-therapy-content .mgmt-options-container .or-connect span {
    font-family: 'MyriadPro-Bold' !important;
}
.ps3 .desk-callout a:after {
    content: '';
    position: absolute;
    width: 14px;
    height: 14px;
    right: 10px;
    transform: rotate(40deg);
    top: 9px;
    border: 3px solid #B2D234;
    border-left: none;
    border-bottom: none;
}
.ps3 .desk-callout.deskcallout-second a:after {
    border: 3px solid #801852;
    border-left: none;
    border-bottom: none;
}
.ps3 .desk-callout a {
    position: relative;
}
.ps3 .desk-callout-but span:after {
    display: none;
}
.ps3 .flag-txt h1 {
    font-family: 'Roboto-Italic';
}
.monotherapy3 .PROfound_wrap p.footnote.smallfont {
    font-size: 10px !important;
    line-height: 12px !important;
    margin-left: 6px;
}
.propel-efficacy .rpfs-p {
    text-indent: -4px;
    padding-left: 4px;
}
.ps3 .homepg-callout {
    /*max-width: 280px;*/
    max-width: 282px;
}
.monotherapy3 .sec66-rpfs li, .monotherapy3 .sec661 {
    font-size: 16px;
    line-height: 20px;
    letter-spacing: 0.5px;
    padding-right: 19px;
}
.monotherapy3 .sec661, .monotherapy3 #sec31-patient {
    position: relative;
    padding-left: 21px;
    margin-bottom:0;
}
.monotherapy3 .sec661:before, .monotherapy3 #sec31-patient:before {
    background: none;
    /* content: '—'; */
    content: '-';
    content: '–';
    color: #333333;
    font-size: 16px;
    line-height: 12px;
    left: 5px;
    position: absolute;
    top: 5px;
}
.monotherapy3 .sec66-rpfs > li::marker{
    color: #333333;
}
.safety-tolerability .platinum_chart {
    margin-bottom: 15px;
}
.safety-tolerability .desk-callout-inner-pdleft {
    padding: 5px 0;
    padding-right: 0 !important;
}
.safety-tolerability .desk-callout-but-arrow span:after {
    right: -45px!important;
}
.patient-profiles .combi-patient-profile .skew-maroon-head {
    max-width: 398px;
}
/*.patient-profiles .wiliam.col-xs-12.col-sm-6 {
    padding-left: 26px;
} */
.patient-profiles.lynparzahcpprostrate .desk-callout {
    max-width: 282px;
}
.mono-patient-profile .desk-callout-inner p {
    padding: 2px 76px 5px 0;
}
.ps3 .mobile-callout .homepg-callout {
    margin-bottom: 30px;
}
.homepg-callout.mob-callout.callut-mob-width {
    max-width: 281px!important;
}
.joe-pot h2, .william-opt h2, .nccn-guidelines.lynparzahcpprostrate  #maincontent h2, .ps3-video #maincontent h2 {
        margin:0;
}
.combinationtherapy3 #test-pg-id {
    padding-top: 10px;
    max-width: 1004px;
}
.propel-efficacy .propel-content .btn-banner.mtop_0 {
    margin-top:0;
}
/* ***********==============Responsive===============*********** */
@media (min-width: 1024px) {
	.home.ps3 .landing-hero-image {
    	/*background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/propel/header-d-3-ps3.png);*/
         background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/propel/header-d-3-ps3-v1.jpg);
	}
    .ps3-combi-dosing .recomended-dose-txt .img-responsive {
    	max-width: 177px;
    	width: 100%;
	}
    .dosing-mono-3.dosing .daily-dose-rec-container,
	.dosing-mono-3.dosing .mgmt-options-container,
	.dosing-mono-3.dosing .dose-discontinuation,
	.dosing-mono-3.dosing .dose-discontinuation-body img.desktop{
    	max-width: 1004px;
	}
	.combinationtherapy3 .section-one h1.container-center {
		max-width: 1024px;
    	margin-left: auto;
	}
	.ps3 .font-boldn {
    	line-height: 15px;
	}
}
@media (min-width: 768px) {
    .tabs_desktop{
        display: block;
    }
    .tabs_mobile{
        display: none;
    }
	.ncci-combi {
    	display: none;
	}
    .propel-efficacy .propel-content.cont-2.green .Primary_endpoint {
    	margin-bottom: 50px;
    	padding-bottom: 25px;
    	padding-top: 10px;
	}
    .combi-therapy-content table.table.table-dose-mod td.green-head span {
        width: 150px;
    }
    .combi-therapy-content table.table.table-dose-mod td.grey-head span {
        width: 150px;
    }
    .propel-content .skew-maroon-head h2 {
        /*max-width: 505px;*/
    	max-width: 900px;
    }



 	.skew-maroon-head-new h2 {
        max-width: 505px;
    }
	.propel-content .skew-maroon-head.last-skew-maroon-head  h2 {
    	max-width: 550px;
    	padding-top: 27px;
    	padding-bottom: 27px;
	}
    .mechanism-of-action .tab-head-container {
        max-width: 1004px;
        margin: 25px auto 32px;
        height: 76px;
    }
    .mechanism-of-action .tab-head-container .tabs-body {
        display: -webkit-box;
        display: -webkit-flex;
        display: -ms-flexbox;
        display: flex;
        justify-content: space-between;
        transform: skewX(10deg);
    }
    .mechanism-of-action.tab-links {
        margin-top: 24px;
    }
    .mechanism-of-action .container-center.thumbnail .col-sm-4 {
        width: 31.5%;
    }
    .mechanism-of-action .tab-head-container .tab-heading h1 {
        margin-top: 10px;
    }
	footnotes.tabs_desktop.tabs_desktop-left p {
    	margin-left: -11px;
	}
	.ps3-video .desc p.desc-head {
    	/*font-size: 20px;*/
    	font-size: 18px;
    	line-height: 24px;
	}
	.ps3-video .desc-body, .ps3-video .desc .boldText {
    	/*font-size: 16px;*/
    	font-size: 14px;
    	line-height: 20px;
    letter-spacing: -0.3px;
	}
	.ps3-video .thumbnail .thumb-head p {
    	font-size: 20px;
    	line-height: 24px;
    	
	}
	.ps3-video .thumbnail .col-xs-12:nth-child(1) div.thumb {
    	margin-top: 0;
	}
	.ps3-video .download-button a {
    	padding: 10px 92px 10px 69px;
	}
	.ps3-video .download-button {
    	padding: 8px 0;
	}
    .propel-efficacy .propel-content.cont-4 .heading p {
    	margin-top: 10px;
	}    
    .propel-efficacy.propel-efficacy .sec-2 .prim-endp .rpfs-p {
		padding-top: 0;
	}
    .monotherapy3 p.explor-subg {
        font-size: 25px;                                                                                 
    }

    p.ast-footnote1 {
    padding-left: 2px;
}
	.footnote-below-landong p {
    	font-family: 'Roboto-Regular';
    	font-size: 14px;
    	line-height: 16px;
    	color: #333333;
    	margin-bottom: 2px;
	}

	h2.explor-subg.explor-subg1.explor-subg111 {
    	font-size: 25px;
    	color: #FFFFFF;
    	font-family: 'Roboto-Bold';
    	margin-left: -7px;
	}
	.propel-content .section-71 .skew-maroon-head h2 {
    	padding: 5px 0;
	}
}

@media (min-width: 992px) {
.footnote-below-landong {
/*padding: 36px 0px 0px 461px;*/
    padding: 36px 0px 0px 185px;
    margin-bottom: -49px;
}
p.footnote.subnote.bold.blk-bld{
	    margin-bottom: 20px;
}
.propel-efficacy p.footnote.subnote.bold.blk-bld {
    margin-bottom: 5px;
    }
.dosing-combination .foot_txt p:last-child span{
	margin-top: 5px;
    display: block;            
}
.dosing-combination #maincontent .combi-therapy-content .dosing-callouts .or p{
	text-align: center;
}
.combi-therapy-content .img-box img:nth-child(4){
	margin-top: -12px !important;
   /* max-width: 80px;*/
   max-width: 101px;
}
.ps3 .homepg-callout {
    margin: 0.5% 4% 0 0;
}

.combinationtherapy3.hrrm-testing .section-two.how-and-when h2 p {
    margin-top: -7px;
}
.hrrm-testing.ps3-mono-testing h2 p.why-test-desc {
    margin-top: -8px;
}
.combi-therapy-content .img-box span:nth-child(5){
	margin-top: 0 !important;
}
	.safety-combination-theraphy .footnotecontiner.container-center {
    	padding-left: 15px;
	}
	.safety-combination-theraphy .desktop.adverse-react-head{
        font-family: 'Roboto-Bold';
        font-size: 17.5px;
        line-height: 18px;
        color: #004D74;
        text-align: left;
        position: relative;
    	top: 88px;
    	left: 192px;
    	    width: fit-content;
    	float: left;
	}
.dosing-mono-3.dosing-page #maincontent h2 p {
    font-size: 25px;
    line-height: 22px;
    margin-top: 30px;
    margin-bottom: -15px;
}
.pc3-combi .container-center.clinicalstudytxt h2 {
    margin: 0;
    font-size: 25px;
    line-height: 28px;
}
.trate-path-head h2.p3-h2, .mechanism-of-action .heading-1 h2 {
    font-size: 25px;
    line-height: 28px;
    margin: 0;
}
.safety-tolerability .container-center.clinicalstudytxt h2 {
    margin: 0;
    font-size: 25px;
    line-height: 30px;
}
p.image-after em:after {
    right: 9.7%!important;
}
p.image-after:after {
    right: 6.7%!important;
}
	.section-one .propel-content.cont-1 .Primary_endpoint{
        margin-top: 60px;
    }
    .safety-combination-theraphy .pink_eyebrow + .container-center.clinicalstudytxt{
        margin-top: 36px !important;
    	padding-right: 175px;
    }
    .combi-therapy-content .dosing-callouts{
        padding-top: 36px !important;
    }
    .combi-therapy-content .daily-dose-rec-container .foot_txt p:first-child {
        line-height: 12px !important;
        font-size: 12px !important;            
    }
    .combi-therapy-content .mgmt-options-container .dose-red-body>p {
        margin-bottom: 10px;
    }
    .dosing-combination .combi-therapy-content .btn-banner a {
        font-size: 18px;
        letter-spacing: -0.27px;
        padding: 12px 10px 12px 20px;
        padding-right: 34px !important;
    }
    .dosing-combination .combi-therapy-content .btn-banner {
        margin-top: 60px;
    }
    .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .recomended-dose-txt {
        padding: 30px 30px 30px 30px;
    }
    .dosing-combination .container-center.inner-wrapper h1 {
        letter-spacing: 0.9px;
    }
    .prim-endp .heading p {
        letter-spacing: 0.25px;
    }
.propel-efficacy p.headingrPFS {
    margin: 11px 0 19px 0!important;
}
    .sensit-analysis .img_sec,
    .prim-endp .img_sec {
        margin-bottom: 5px;
    }
.container-center.footnote_end.paddingLeft10.m-paddingLef20.margintop0 {
    /*padding-left: 16px!important;*/
    padding-right: 26px!important;
}
.monotherapy3 .secondary_endpoint {
    padding-bottom: 60px;
}
 /*.monotherapy3 .container-center.skew-maroon-head.skew-maroon-head-wdt.skew-maroon-head-wdt-h2 {
    width: 46%;
    margin-left: 32%;
}*/
   .monotherapy3 .Primary_endpoint {
   /* margin: 40px auto 40px auto!important;*/
    margin: 50px auto 16px auto!important;
}
.safety-combination-theraphy .pink_eyebrow h1.container-center {
    margin-bottom: 0;
}
    .sensit-analysis .footnote.subnote,
    .prim-endp .footnote.subnote {
        /*font-size: 18px !important;*/
		font-size: 20px !important;
        line-height: 24px !important;
    	letter-spacing: -0.1px;
    }
    section.propel-content.sec-2.bg-yellow .Primary_endpoint {
        margin-top: 30px;
        padding: 40px 0 0;
    }
    .propel-content .btn-banner {
        max-width: 240px;
    	height: 45px;
    }
    .propel-content .btn-banner a {
        padding: 10px 10px 10px 20px;
    	    font-size: 18px;
    	letter-spacing: -0.27px;
    }
    .propel-content .footnote.f2note {
        margin-top: -10px;
        margin-bottom: 45px;
    }
    .combi-therapy-header.propel-header .common-headline {
        padding-top: 20px !important;
        padding-bottom: 34px !important;
    }
    section.propel-content.sec-2 {
        max-width: 100%;
        background: #F8FFF7;
    }
p.bold.sub-85-font {
    line-height: 20px;
    margin-bottom: 0px;
}
    .propel-content .skew-maroon-head {
       /* padding-right: 85px;*/
    	padding-right: 45px;
        margin-top: 0;
    }
.hrrm-testing.ps3-mono-testing h2 p.recommend_based {
    margin-bottom: -9px;
}
.ps3-combi-dosing .combi-therapy-content .heading h2 p {
    margin-top: -15px;
}
/*for maroon new box start*/
  .skew-maroon-head-new {
    background-color: #990064;
    padding: 1px 42px;
    transform: skewX(170deg);
    margin: 10px auto 28px;
    margin-left: 15px;
   /* width: fit-content;*/
 	width: 189px;
    height: 33px;
    }
.skew-maroon-head-new_sf{
    padding-right: 85px;
    background-color: #990064;
    padding: 1px 42px;
    transform: skewX(170deg);
    margin: 35px auto -20px;
    margin-left: 5px;
    width: fit-content;
}
    .skew-maroon-head-new_ba {
    padding-right: 85px;
    background-color: #990064;
    padding: 1px 54px;
    transform: skewX(170deg);
    margin: 35px auto -20px;
    margin-left: 5px;
    width: fit-content;
}
.patient-profiles .combi-patient-profile .david-skew.skew-maroon-head h2 {
    font-size: 18px;
    line-height: 23px;
    text-align: center;
    margin-bottom: 0;
    margin: 0;
    padding: 14px 12px;
    transform: skewX(10deg);
}
/*for maroon box end*/
    .combi-therapy-content .dosing-callouts {
        padding-top: 6px;
        padding-bottom: 18px;
    }
    .combi-therapy-content .daily-dose-rec-container {
        margin: 0 auto 5px;
        max-width: 1024px;
    }
    .combi-therapy-header .common-headline {
        padding-top: 53px !important;
        padding-bottom: 67px !important;
    }

.ps3-combi-dosing .common-headline.solo-heading {
    padding-bottom: 27px !important;
}
    .combi-therapy-header .solo-heading h1 sup {
        font-size: 16px !important;
    }
    .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .recomended-dose-txt {
        width: 50%;
        max-width: 414px;
        margin-right: 15px;
        height: 210px;
    }
    .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic {
        width: 54%;
        max-width: 560px;
        height: 210px;
        padding: 48px 16px 30px 22px;
    }
    .foot_txt {
        /*display: flex;*/
        margin-left: 0px;
    }
    .foot_txt p:first-child {
        width: 97%;
    	text-align: right;
    }
    .foot_txt p:last-child {
        width: 98%;
    	margin-bottom: 20px;
    }
    .combi-therapy-content .mgmt-options-container {
        max-width: 1024px;
        margin: 0 auto 15px;
    }
.mgmt-options-container.bg-heading-tp {
    margin: 53px auto 15px!important;
}
    .combi-therapy-content .dose-interrupts {
        max-width: 353px;
        width: 100%;
    }
    .combi-therapy-content .dose-reduces {
        max-width: 598px;
        width: 100%;
    }
    .combi-therapy-content .mgmt-options-container .mgmt-opt-flex {
        align-items: start;
        justify-content: space-between;
    }
    .combi-therapy-content .mgmt-options-container .mgmt-opt-flex p {
        text-align: center;
    }
    .combi-therapy-content .mgmt-head>p {
        padding: 6px 0 4px;
        margin-bottom: 0;
    }
    .combi-therapy-content .mgmt-options-container .dose-int-body {
        padding: 5px 0;
    }
    .combi-therapy-content .mgmt-options-container .dose-int-body img.desktop {
        margin: 0 auto;
        padding: 25px 10px 0;
    }
    .combi-therapy-content .mgmt-options-container .dose-int-body p {
        line-height: 18px !important;
        padding: 20px 40px 54px 40px;
    }
    .combi-therapy-content .mgmt-options-container .or-connect {
        padding: 8px 15px;
        margin: 0 -20px 0 -20px;
        transform: none;
    }
    .combi-therapy-content .mgmt-options-container .or-connect span {
        display: inline-block;
        font-size: 17px;
        line-height: 27px;
        color: #333;
    }
    .combi-therapy-content .mgmt-options-container .dose-int-body {
        padding: 0 30px;
    }
	.combi-therapy-content .mgmt-options-container .dose-red-body{
		padding: 0 20px;
	}
    .combi-therapy-content .mgmt-options-container .dose-red-body>p:first-child {
        padding-top: 10px;
        font-size: 16px !important;
        line-height: 20px !important;
        color: #333;
    	padding-left: 10px;
    }
    .combi-therapy-content .mgmt-options-container .init-reduce,
    .combi-therapy-content .mgmt-options-container .final-reduce {
        padding: 10px 0 0;
        width: calc(50% - 15px);
        margin-right: 7.5px;
        margin-left: 7.5px;
        float: left;
        margin-bottom: 12px;
    }
    .combi-therapy-content .mgmt-options-container .final-reduce {
        margin-right: 0;
        margin-left: 7.5px;
    }
    .combi-therapy-content .mgmt-options-container .mgmt-opt-flex {
        align-items: start;
        justify-content: space-between;
    }
    .combi-therapy-content .mgmt-options-container .mgmt-opt-flex p.init-dose-txt,
    .combi-therapy-content .mgmt-options-container .mgmt-opt-flex p.final-dose-txt {
        font-size: 13px !important;
        line-height: 14px !important;
        max-width: 165px;
        font-family: "Roboto-Regular" !important;
    }
	p.final-dose-txt.desktop.space {
    	max-width: 157px!important;
	}
	p.tab-descript.center-align {
    	margin-left: -34px;
	}

    .combi-therapy-content #maincontent .dosing-callouts .or p {
        margin-top: 15px;
        margin-bottom: 37px;
        font-size: 14px;
        line-height: 11px;
    }
    .combi-therapy-content .mgmt-options-container .init-reduce p:first-child,
    .combi-therapy-content .mgmt-options-container .final-reduce p:first-child {
        text-align: right !important;
    }
    .combi-therapy-content .mgmt-options-container .dose-int-body p {
        font-size: 18px !important;
        line-height: 23px !important;
        color: #333;
        max-width: 192px;
        padding: 15px 0px;
        margin: 0 auto;
    }
    .combi-therapy-content .btn-banner {
        max-width: 240px;
    }
    .combi-therapy-content .btn-banner a {
        padding: 10px 10px 10px 20px;
    }
    .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic p.sub-head {
        line-height: 34px !important;
    	    margin-bottom: 0;
    }
    .combi-therapy-content .img-text {
        margin-left: 15px;
    }
	.ps3-mono-testing .pink_eyebrow .container-center {
    	/*max-width: 829px; */
        max-width: 900px;
	}
            h1.container-center.container-centers1.container-centers-left {
    /* padding-left: 12px; */
    max-width: 1024px;
    margin-left: auto;
}
    .ps3-mono-testing .section-two.how-and-when {
    	margin-top: 30px;
    	margin-bottom: 17px;
	}
    .ps3-combi-dosing .mgmt-options-container {
        margin-top: 56px;
        margin-bottom: 30px;                            
    }  
    .ps3-combi-dosing p.tab-descript.center-align {
    	margin-left: 0;
	}  
	.prostrate_efficacy.monotherapy3 h1.container-center.pr-p3.pr-p3-pad {
    	font-family: 'Roboto-Bold';
	}
    .prostrate_efficacy.monotherapy3 .secondary_endpointPFS p.cohort-txt.sk-new.sk-new-orr-n {
    	padding-right: 97px;
	}
	.patient-profiles .combi-patient-profile .med-facts .width500 {
    width: auto;
}
.patient-profiles .combi-patient-profile .med-facts .mCRPCw {
    width: auto;
}
.patient-profiles .joe-history {
	padding-right: 0;
}
}

@media (max-width: 1023px) {
	.home.ps3 .landing-hero-image {
		/*background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/propel/mobile/header-m-3-prople3.png);*/
        background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-prostrate/propel/mobile/header-m-3-prople3.jpg);
	}
    .combi-therapy-header .solo-heading h1 {
        font-size: 24px !important;
        line-height: 30px !important;
        font-style: italic !important;
        font-family: 'Roboto-Bold' !important;
        margin: 0;
    }
    .combination-therapy .outside-rep-section {
       /* z-index: 1;*/
    }
    .combi-therapy-content .daily-dose-rec-container .dosage-body-flex {
        display: flex;
        flex-direction: column;
    }

	p.footnote.fin-an {
    	font-size: 12px !important;
    	line-height: 14px !important;
	}
	.mobile.container-center.financial-analysys-end {
    	margin-top: 22px;
	}

}

@media (max-width: 991px) {
    .combi-therapy-header .solo-heading p {
        margin-bottom: 3px;
    }
	.lynparzahcpprostrate .mobile.col-xs-12.col-sm-6.william-pot {
    	padding-left: 24px;
    	padding-right: 24px;
    	margin-bottom: 20px;
	}
	.monotherapy3 .sec661, .monotherapy3 #sec31-patient {
        padding-left: 30px;
    	text-indent: 0px;
	}
	.ps3 .homepg-callout.mob-callout .desk-callout-inner p {
    	letter-spacing: -0.01px;
	}
	.monotherapy3 .sec66-rpfs, .monotherapy3 .sec31-rpfs {
    	text-indent: 0px;
    	padding-left: 15px;
        padding-top: 10px;
	}
    .sec31-rpfs .first-li, .sec31-rpfs .second-li, #sec31-patient {
		padding-bottom : 6px;
	}
    .monotherapy3 .sec661:before, .monotherapy3 #sec31-patient:before {
    	left: 20px;
    }
	.ps3-combi-dosing .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .recomended-dose-txt p {
    	padding-right: 16px;
	}
	.dosing-mono-3.monotherapy .refs.reference .container-center.inner-wrapper {
    	padding-left: 0;
	}
	.monotherapy3 .sec661.sec66-patient2 span:last-child {
    	display: initial;
	}
	.pc3-combi.safety-tolerability .section-two .platinum_chart.mobile img {
    	margin-top: -20px;
	}
	.ps3-mono-testing.hrrm-testing .col-xs-12.col-sm-6.ctdna-test p.subheadingtwo, 
	.ps3-mono-testing.hrrm-testing .col-xs-12.col-sm-6.ctdna-test p.subheadingtwo + p {
    	color: #000000;
	}
	.safety-tolerability .desk-callout-but-arrow span:after {
    	right: -94px!important;
	}
	.Primary_endpoint.section-71 {
    	padding-left: 10px;
    	padding-right: 20px;
	}
	.propel-efficacy p.sub-head{
		font-size: 20px;
    	line-height: 20px;
	}
	.skew-maroon-head-new.skew-maroon-head-new_ba {
    	margin-left: 5px;
	}
	.propel-efficacy  .btm-txt{
		max-width: 100%;
	}
	.profound.efficacy.monotherapy3 .Primary_endpoint.section-78 .container-center.skew-maroon-head.pink78.pink78-new {
    	left: 0 !important;
    	margin-left: -11px !important;

	}
    .profound.efficacy.monotherapy3 .Primary_endpoint.section-78 .container-center .pink78-pg {
    	font-size: 20px;
   	 	line-height: 26px;
    	padding-right: 35px;
	}  
    .profound.efficacy.monotherapy3 .secondary_endpoint {
    	padding-bottom: 20px;
	}                                                                            
    .profound.efficacy.monotherapy3 .Primary_endpoint .container-center.skew-maroon-head {
        max-width: 283px; 
    }
    .profound.efficacy.monotherapy3 .Primary_endpoint .container-center.skew-maroon-head h2{
    	padding-right: 0;                                                                
	}
	.hrrm-testing .biopsycontent.mobile .sectionright .contentwrap.sectiontwo .telephone-cont {
    	padding-right: 70px;
	}
	.hrrm-testing.combinationtherapy3 h1.container-center {
    	letter-spacing: -0.4px;
	}
	.patient-profiles.lynparzahcpprostrate .combi-patient-profile .patient-profile-wrap {
    	padding-bottom: 10px;
	}
.mono-patient-profile .desk-callout-inner p {
        line-height: 16px;
}
	.skew-maroon-head.last-skew-maroon-head{
	    padding: 17px 40px 17px 18px !important;
	}
	.combi-therapy-content .daily-dose-rec-container .foot_txt p:first-child {
    	font-size: 12px !important;
	}
	.dosing-combination .foot_txt p:last-child span {
    	margin-top: 5px;
    	display: block;
	}
	.dosing-combination .combi-therapy-header .common-headline{
		padding-top: 50px;
	}  
	.combi-therapy-content .mgmt-options-container{
		margin-top: 20px;
	}
	.patient-profiles.lynparzahcpprostrate .joe .pat-detail h4 {
    	letter-spacing: -1px;
	}
	.patient-profiles.lynparzahcpprostrate .pat-detail.pat-detail2 {
    	padding-left: 0;
	}
    .patient-profiles.lynparzahcpprostrate .pat-detail h4.second {
    	padding-right: 13px;
	}    
	.ps3-video .video-callouts {
    	width: auto !important;
	}
	.hrrm-testing.ps3-mono-testing h2 p.why-test-desc {
    	margin-top: 0px;
	}
	.pc3-combi .container-center.clinicalstudytxt h2 {
    margin: 0;
    font-size: 20px;
    line-height: 24px;
}
.trate-path-head h2.p3-h2, .mechanism-of-action .heading-1 h2 {
    font-size: 20px;
    line-height: 24px;
    margin: 0;
}
.safety-tolerability .container-center.clinicalstudytxt h2 {
    margin: 0;
    font-size: 20px;
    line-height: 26px;
}
.ps3-combi-dosing .combi-therapy-content .heading h2 p {
    margin-top: -20px;
}

.dosing-mono-3.dosing-page #maincontent h2 p {
    margin-top: 10px;
    margin-bottom: 10px;
}
.dosing-combination .combi-therapy-content .dose-interrupts .dose-int-body p{
	    font-size: 16px !important;
    line-height: 20px !important;
	color: #333333 !important;
}
.combi-therapy-content .bg-heading p{
	font-family: 'MyriadPro-Bold' !important;
}
.combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic p.sub-head {
    font-family: 'Roboto-Bold' !important;
}
.combi-therapy-content .daily-dose-rec-container .dosage-body-flex{
	padding-top: 0;
}
.combi-therapy-content .mgmt-options-container .init-reduce, 
.combi-therapy-content .mgmt-options-container .final-reduce{
	    background: #B2D23440;
}
.combi-therapy-content .mgmt-options-container .dose-red-body >p,
.combi-therapy-content .mgmt-options-container .init-reduce p, .combi-therapy-content .mgmt-options-container .final-reduce p {
    color: #333333 !important;
}
.prostrate_efficacy.monotherapy3 h1.container-center.pr-p3.pr-p3-pad {
	font-family:'Roboto-Black' !important;
}
.combi-therapy-content .mgmt-options-container .final-reduce  .reduce-txt-span{
	margin-top: 15px;
}
	.cont-1 .Primary_endpoint .skew-maroon-head{
	    margin-left: 0;
    	    margin-top: 0;
	}
.skew-maroon-head-new {
    margin-left: 12px;
    margin-top: 30px;
    margin-bottom: -24px;
    padding: 5px 38px!important;
}
    .propel-content .btn-banner {
        margin-right: 8px;
    }
    .propel-content .btn-banner a {
        padding: 10px 20px;
        padding-right: 22px !important;
    }
    .propel-content .btn-banner a:after {
        right: 2px !important;
    }
    .propel-content1 .btn-banner1 a:after {
        right: -20px!important;/*added for iphone 8 browser stack issue*/

    }

    p.sub-head {
        font-size: 16px;
        line-height: 16px;
        ;
    }
    .heading.pink-skew h5.bold:first-child {
        padding-left: 9px;
    }
	.heading.pink-skew h5.bold:nth-child(2){
		padding-left: 20px;
    }
    .heading.pink-skew h5.bold:last-child {
        padding-left: 20px;
    }
    .heading.pink-skew {
        padding: 10px 14px;
    }
    span.img-txt.mobile {
        font-size: 14px;
        line-height: 16px;
        color: #333;
        max-width: 290px;
        display: block !important;
        margin: 10px auto 20px;
    	/*font-family: 'MyriadPro-Regular';*/
    font-family: 'Roboto-Regular';
    }
.margintop10.ipadp-mtop20.font-10 p {
    font-size: 12px!important;
    line-height: 14px!important;
     padding-left: 0px!important; 
}
    .propel-content .Primary_endpoint {
        margin: 40px auto 50px auto;
    }
section.propel-content.sec-2.bg-yellow.cont-4 .Primary_endpoint{ margin-bottom: 0; }
	section.propel-content.sec-2.cont-2 .Primary_endpoint {
        margin-top: -55px;
    	margin-bottom: -30px;
    }
section.propel-content.sec-2.cont-2.green {
    background: #F8FFF7;
}


    .propel-content .heading p {
        font-size: 20px !important;
        line-height: 26px !important;
        margin: 30px 0 20px 0;
    	/*letter-spacing: 0;*/
    	/*letter-spacing: 1px;*/
    }
    section.propel-content.cont-3 .heading.mt p {
        margin: 40px 0 15px 0;
    }
	section.propel-content.sec-2.bg-yellow.cont-4 .heading p {
        margin: 21px 0 20px 0;
    }
    .cont-4.propel-content .Primary_endpoint{
        margin-top: 30px;
    }
    .propel-content .skew-maroon-head h2 {
        font-size: 16px;
        line-height: 27px;
    }
	.propel-content.cont-2 .skew-maroon-head h2 {
        font-size: 16px;
        line-height: 20px;
    	padding: 15px 0px;
    }
	.propel-content.cont-2 .skew-maroon-head {
        max-width: 310px;
    }
.skew-maroon-head.skew-lyn-abi {
    margin-left: 13px;
}

span.line-break {
    display: inline!important;
}
    .combi-therapy-content .heading p {
        font-size: 20px !important;
        line-height: 24px !important;
        margin: 0px 0 30px 0;
    }
    .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .recomended-dose-txt {
        max-width: 94%;
        width: 500px;
        margin: 0 auto;
        margin-bottom: 15px;
        padding: 16px 4px;
        transform: skewX(175deg);
        height: 170px;
    }
    .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic {
        max-width: 94%;
        width: 500px;
        margin: 0 auto;
        margin-bottom: 15px;
        padding: 16px 4px;
    	padding-bottom: 6px;
        transform: skewX(175deg);
    }
    .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .recomended-dose-txt p {
        transform: skewX(-175deg);
    	    font-family: 'MyriadPro-Regular' !important;
    }
    .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic p {
        transform: skewX(-175deg);
    }
	.combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic p.pr-40-mob {
        padding-right: 40px;
    }
    p.pr-40-mob.pr-40-mob11 {
    padding-right: 43px!important;
}
    .combi-therapy-content .img-text {
        transform: skewX(-175deg);
        display: flex;
        justify-content: flex-start;
        align-items: center;
        padding: 0 18px;
    }
    .combi-therapy-content .img-text img {
        max-width: 45%;
    }
    .combi-therapy-content .img-box {
        transform: skewX(-175deg);
        max-width: 22%;
    	margin-top: 0px;
    }
	.ps3-combi-dosing .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic {
    	margin-bottom: 5px;
    }
    .combi-therapy-content .img-box img:first-child {
        transform: scale(1.8);
        position: relative;
        left: -20px;
        top: -10px;
    } 
    .combi-therapy-content .img-box img:nth-child(4) {
        transform: scale(.95);
    }
    .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .recomended-dose-txt p.sub-head {
        font-size: 18px !important;
        line-height: 13px !important;
        margin-bottom: 5px;
        padding-left: 10px;
    }
    .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic p.sub-head {
        font-size: 18px !important;
        line-height: 22px !important;
        margin-bottom: 5px;
        padding-left: 8px;
    	    white-space: nowrap;
    	font-family: 'Roboto-Bold' !important;
    }
    .combi-therapy-content .text-box {
        width: 74%;
    }
    .combi-therapy-content .img-text span {
        font-size: 16px;
        line-height: 27px;
    }
    .combi-therapy-content div.divider {
        margin-bottom: 10px;
    	margin-top: -7px;
    }
    .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic span {
        font-size: 16px;
    }
    .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic p:nth-child(4) {
        padding-left: 10px !important;
    }
    .combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic p:last-child {
        padding-left: 14px;
    	padding-right: 20px;
    }
    p.left-mgs {
    padding-right: 24px!important;
}
	.combi-therapy-content .daily-dose-rec-container .dosage-body-flex .dosage-graphic p:last-child br{
		display: none;
	}
    .foot_txt {
        margin-top: -5px;
    }
    .foot_txt p {
        padding-right: 20px;
    }
    .combi-therapy-content .plus-img {
        position: absolute;
        top: 160px;
        left: 50%;
        transform: translateX(-50%);
    }
    .combi-therapy-content .plus-img img {
        max-width: 46px;
    }
    .combi-therapy-content .dosing-callouts {
        padding-top: 25px !important;
    	padding-bottom: 0;
    }
    .combi-therapy-content .mgmt-options-container .mgmt-opt-flex {
        flex-direction: column;
    }
    .combi-therapy-content .mgmt-head>p {
        font-size: 18px !important;
        padding: 7px 0;
        padding-bottom: 3px;
        margin-bottom: 2px;
    }

        .combi-therapy-content .mgmt-options-container .mgmt-opt-flex .mgmt-head p {
            font-size: 19px !important;
            line-height: 30px !important;
        }
    .combi-therapy-content .mgmt-options-container .dose-int-body {
        text-align: center;
        padding: 10px 10px;
    }
    .combi-therapy-content .mobile.border-for-or {
        border: none;
        width: 60%;
        margin: 30px auto 0;
    }
    .combi-therapy-content .mgmt-options-container .or-connect {
        padding: 15px 0;
        text-align: center;
        margin-top: -25px;
    }
    .combi-therapy-content .mgmt-options-container .dose-red-body {
        padding: 5px 10px 15px;
    }
    .combi-therapy-content .mgmt-options-container .init-reduce,
    .combi-therapy-content .mgmt-options-container .final-reduce {
        justify-content: center;
        align-items: flex-start;
        padding: 16px 0;
    }
    .combi-therapy-content span.upcase {
        white-space: nowrap;
        font-size: 16px;
    	line-height: 16px;
    }
    .combi-therapy-content .mgmt-options-container .init-reduce p>span.reduce-txt-span,
    .combi-therapy-content .mgmt-options-container .final-reduce p>span.reduce-txt-span {
        font-size: 14px !important;
        position: relative;
        right: -20px;
    }
    .combi-therapy-content .mgmt-options-container .init-reduce p,
    .combi-therapy-content .mgmt-options-container .final-reduce p {
        text-align: right !important;
        line-height: 24px !important;
    }
    .combi-therapy-content .mgmt-options-container .dose-red-body p,
    .combi-therapy-content .mgmt-options-container .dose-int-body p {
        font-size: 16px !important;
        line-height: 20px !important;
        color: #333;
        text-align: center;
        margin-top: 10px;
    }

	.combi-therapy-content .mgmt-options-container .dose-red-body>p:first-child {
        line-height: 18px !important;
    	    font-size: 16px !important;
    }
	.combi-therapy-content .mgmt-options-container .mgmt-opt-flex p.init-dose-txt .bold, 
	.combi-therapy-content .mgmt-options-container .mgmt-opt-flex p.final-dose-txt .bold{
	    font-family: "MyriadPro-Bold" !important;
	}
	.combi-therapy-content .mgmt-options-container .mgmt-opt-flex p {
        font-family: 'MyriadPro-Bold' !important;
        color: #004D74;
        font-size: 18px !important;
        line-height: 28px !important;
    }
	.combi-therapy-content .mgmt-options-container .dose-red-body p, .combi-therapy-content .mgmt-options-container .dose-int-body p {
        line-height: 16px !important;
    }
    .combi-therapy-content .mgmt-options-container .dose-int-body p {
        margin: 0 auto;
        margin-top: 20px;
        max-width: 170px;
    }
    .combi-therapy-content .mgmt-options-container .init-reduce,
    .combi-therapy-content .mgmt-options-container .final-reduce {
        justify-content: center;
        align-items: center;
        padding: 10px 0;
        padding-top: 0;
        margin-bottom: 28px;
    }
	.combi-therapy-content .mgmt-options-container .init-reduce .img_box, .combi-therapy-content .mgmt-options-container .final-reduce .img_box {
        margin-top: -8px;
    }
    .combi-therapy-content .mgmt-options-container .final-reduce {
        margin-bottom: 4px;
    }
    .combi-therapy-content .dosing-callouts .or {
        padding: 0 15px;
    }
    .combi-therapy-content .mgmt-options-container .or-connect span {
        background-color: #FFFFFF;
        padding: 0 20px;
        color: #333;
        font-size: 17px !important;
        line-height: 27px !important;
    }
    .combi-therapy-content .mgmt-options-container .init-reduce img.mobile,
    .combi-therapy-content .mgmt-options-container .final-reduce img.mobile {
        max-width: 105px;
        margin-left: 0;
    	width: 100%;
    }
    .combi-therapy-content .dose-interrupts .dose-int-body,
    .combi-therapy-content .dose-reduces .dose-red-body {
        background-color: #E8F1CF80;
        min-height: auto;
        padding-bottom: 24px !important;
    }
.combi-therapy-content .dose-reduces .dose-red-body{
	padding-bottom: 0!important;
}

img.mobile.mobilimg-width {
    max-width: 129px!important;
}
.dosing-callouts .dose-reduces .dose-red-body .tab-descript{padding-top: 5px;}
    .dosing-combination #maincontent .combi-therapy-content .dosing-callouts .or p {
        margin-top: 5px;
        font-size: 12px;
        line-height: 14px;
        color: #333;
        font-family: "Roboto-Bold";
        text-align: left;
    }
    .combi-therapy-content .mgmt-options-container .mgmt-opt-flex p.init-dose-txt,
    .combi-therapy-content .mgmt-options-container .mgmt-opt-flex p.final-dose-txt {
        font-size: 12px !important;
        line-height: 14px !important;
        font-family: 'MyriadPro-Regular' !important;
        max-width: 90%;
        margin: 0 auto;
        text-align: center !important;
    }
    .combi-therapy-content .bg-heading {
        padding: 7px 20px 7px 20px;
    	margin-bottom: 12px;
    }
    .combi-therapy-content .bg-heading p {
        font-size: 16px !important;
        line-height: 20px !important;
    }
    .combi-therapy-content .txt-banner {
        padding: 20px 26px;
        max-width: 820px;
        width: 95%;
        margin-top: 35px;
        transform: skewX(177deg);
    }
    .dosing-combination #maincontent .combi-therapy-content .dose-discontinuation .dose-discontinuation-body .txt-banner p {
        font-family: "Roboto-Bold";
        font-size: 18px !important;
        line-height: 22px !important;
    }
    .combi-therapy-content .btn-banner {
        margin-right: 8px;
    }
    .combi-therapy-content .btn-banner a:after {
        right: 2px !important;
    	top: 13px;
    }
    .combi-therapy-content .btn-banner a {
        padding: 10px 20px;
        padding-right: 22px !important;
    	letter-spacing: -0.24px;
    }
.ps3 .desk-callout.deskcallout-first {
    padding: 4px 12px 7px 12px;
}
.desk-callout.deskcallout-first.deskcallout-firsts1 {
        padding: 4px 12px 7px 12px!important;
}
.homepg-callout .deskcallout-second {
    position: relative;
    right: 17px;
        top: -5px;
}
.desk-callout.deskcallout-second.deskcallout-second-pad {
    padding: 4px 15px 9px 13px;
}
/*button.navbar-toggle.menu-close span:nth-child(2) {
display: none!important;
}*/

.saftey-mob-btn {
    width: 280px;
}
.saftey-mob-btn .desk-callout-but span:after { right: -130px;}
.ps3 .desk-callout-inner p {
    line-height: 19px;
}
p.line-h21 {
    font-family: 'Roboto-BlackItalic';
    line-height: 21px!important;
}
.ps3 .desk-callout a:after {
    content: '';
    position: absolute;
    width: 14px;
    height: 14px;
    right: 10px;
    transform: rotate(40deg);
    top: 9px;
    border: 3px solid #B2D234;
    border-left: none;
    border-bottom: none;
}
.ps3 .desk-callout a {
    position: relative;
}
.ps3 .desk-callout-but span:after {
    display: none;
}
.desk-callout.deskcallout-second .desk-callout-but {
    color: #801852;
}

.ps3 .desk-callout.deskcallout-second a:after {
    border: 3px solid #801852;
    border-left: none;
    border-bottom: none;
}
	.monotherapy3.profound .orr-a p.cohort-txt, .monotherapy3.profound .orr-ab p.cohort-txt {
    	padding: 0 4px 0 4%;
	}

.profound .cohort-container.cohort-container2 {
    margin-left: 19px!important;
}
.profound .cohort-container.cohort-container12 .orr-a {
    margin-left: 0px!important;
    padding-left: 3px;
    padding-right: 2px !important;
}
	.monotherapy3.profound p.cohort-foot.sk-new.sk-new-padding-left {
    	padding-left: 25px!important;
	}
    .monotherapy3.profound .orr-a h2 {
    	padding: 0 0 0 0%;
	}
    .monotherapy3.profound .cohort-foot.sk-new.sk-new-l2 {
    	padding: 0 0 0 32px !important;
	}
	.monotherapy3.profound .cohort-container.cohort-container2 .orr-ab {
    	padding-right: 5px;
     }
	.monotherapy3.profound p.cohort-foot.sk-new.sk-new-l1 {
    	padding-left: 25px!important;
	}
    .monotherapy3.profound .orr-ab p.cohort-txt {
    	padding-right: 0;
    }
	.monotherapy3.profound .cohort-container.cohort-container2.cohort-container2n {
    	width: 89%!important;
	}
    .monotherapy3.profound .orr-ab p, .monotherapy3.profound .orr-a p {
    	color: #004D74;
	}
    .ps3-combi-dosing .common-headline.solo-heading {
    	padding-right: 26px;
	}
	.ps3-mono-testing.hrrm-testing h1.container-center {
	    letter-spacing: -0.2px;
	}
    .dosing-mono-3.dosing-page #maincontent .recomended-dose-txt p:first-child {
        font-size: 16px;
    	line-height: 20px; 
        padding-right: 25px;                
    }
	.dosing-mono-3.dosing-page #maincontent .dose-discontinuation h2 {
    	font-size: 20px !important;
    	line-height: 24px;

	}
span.line-break-new {
    display: block;
}
.dosing-mono-3 .refs.reference .container-center.inner-wrapper p {
    font-family: 'Roboto-Regular';
    font-size: 16px!important;
    line-height: 20px;
}
/*refrence and abri*/
.reference {
    padding-left:20px!important;
   /* padding: 0px 21px 0px 20px!important;*/
}


    /*.dosing-mono-3 .container-center.inner-wrapper {
    	padding-left: 0px;
	}*/
}
@media (min-width: 767px) {
	.lynparzahcpprostrate.patient-profiles .tab-head-container,
    .moa.mechanism-of-action .tab-head-container.pd-left,
	.nccn-guidelines.lynparzahcpprostrate  .tab-head-container,
    .ps3-video.video-library .tab-head-container {
    	max-width: 992px;
	}
}
@media (max-width: 767px) {
    .margintop50.wheretxt {
        margin-top: 0px;
    }
	.propel-efficacy.propel-efficacy .cont-4 .end-eff-cont .end-eff-cont-os {
    	margin: -10px auto -20px;
	}
	.pink39-pg {
    	font-size: 20px;
    	line-height: 25px;
    	letter-spacing: 1px;
	}
	.monotherapy .pink39-pg {
		letter-spacing: normal;
        }
    .monotherapy3 .last78-pg {
    	line-height: 20px;
	}
    .propel-efficacy p.explor-subg, .propel-content .skew-maroon-head h2 {
    	line-height: 20px !important;
    	margin-top: 0 !important;
    	padding-left: 8px;
	} 
	.Primary_endpoint span.img-txt.mobile {
   	 	max-width: 328px;
    margin: 5px 0;
	}
	.propel-content .Primary_endpoint.section-71 .skew-maroon-head h2 {
    	padding: 10px 0 10px 8px;
	}
	.combination-therapy.propel.propel-efficacy .sec71bg {
    	width: 99%!important;
	}
	p.pink39-pg.pink39-pg39 {
    	padding-top: 0px;
    	padding-bottom: 0px;
	}
.footnote-below-landong {
    padding: 20px 28px 0px 20px;
}
.footnote-below-landong p {
    line-height: 16px;
    font-size: 14px;
    margin-bottom: 5px;
    color: #333333;
    font-family: 'Roboto-Regular';
}
	.Primary_endpoint-text-blue31 {
    	font-size: 20px!important;
    	padding-right: 50px;
	}
	p.color-brown25, p.color-brown31 {
    	font-size: 20px!important;
    	line-height: 26px!important;
	}
	.Primary_endpoint-text-blue {
    	font-size: 20px!important;
	}
	.pink78 {
    	position: relative;
    	left: 0px !important;
	}
	.last78-pg {
    	padding-top: 10px;
	}

	p.explor-subg {
    	font-size: 13px;
    	margin-left: 14px;
    	transform: skewX(10deg);
    	margin-top: 1px;
	}
	.section-78 h2 { margin-bottom: 0px !important; }
	.profound .Primary_endpoint .container-center h2 {
   		/* word-spacing: 3px;*/
    	padding-right: 65px;
    	line-height: 20px;
	}
	h2.explor-subg.explor-subg1.explor-subg111 {
    	margin-left: -6px;
        font-size: 13px !important;
	}
	.mobile-show {
		display: block;
   		font-size: 12px;
  	    font-family: 'Roboto-Bold';
    	margin-top: 5px;
   		/* letter-spacing: 0.9px;*/
    	line-height: 14px;
	}
	p.pg77.pgs {
    	letter-spacing: 0.03em;
	}
    .rpfs-footn-mobile {
		display: block;
    	font-size: 14px;
    	font-family: 'Roboto-Regular';
    }
    #mobile20 {
		font-size: 20px !important;
    	/*letter-spacing: 1px;*/
        letter-spacing: 0.03em;
    	padding-bottom: 10px;
     }

.propel-efficacy p#mobile20 {
    font-size: 16px !important;
    margin-bottom: -10px;
    letter-spacing: 0px;
}
    .pg77, .event77 {
		line-height: 19px !important;
    	margin-bottom: 10px !important;
    }
 	.brca-subgrp {
        margin-bottom: 3px;
    	margin-top: 10px;
	}
	.nccn-guidelines main#maincontent {
    	margin-top: 90px !important;
	}
	.rpfs-p {
		font-size: 12px;
    	margin-bottom:3px;
    }
    .rpfs-footn {
		font-size: 12px;
     }
	.propel-efficacy .rpfs-p {
    	text-indent: -5px;
	}
    .tabs_desktop{
        display: none;
    }
    .tabs_mobile{
        display: block;
    }
	.in-active +.ncci-combi,
	.in-active +.ncci-mono{
		display: none;
	}
	.in-active +.nccn-mono .nccn-rec.tabs_mobile {
    	display: none;
	}
	.nccn-mono.in-active {
    	display: none;
	}
	.combi-therapy-content .mgmt-options-container .mgmt-opt-flex p.final-dose-txt.mobile br {
        display: none;
    }
    .propel-efficacy main#maincontent {
        margin-top: 90px !important;
    }
    .btm-txt {
        float: left;
        max-width: 63%;
        margin-bottom: 25px;
    }
    .propel-content .skew-maroon-head {
        padding: 15px 16px;
        padding-right: 16px;
        box-shadow: 4px 4px 0px 1px #b2d234;
    }

	.nccn-rec.tabs_mobile .nccn-inner .image-sec.image-second span {
    	font-size: 20px !important;
	}
	.nccn-rec.tabs_mobile .nccn-inner .image-sec.image-second {
    	line-height: 20px;
        padding-top: 43px;
        padding-left: 20px;
    	padding-right: 20px;                
    	height: 126px;
	}
.resource-library.video-library.ps3-video .hcp-res p.down-res.down-res-new-res {
    padding-right: 0px!important;
    margin-left: -15px;
}
                .resource-library.video-library.ps3-video .hcp-res .double-pan-column.second-grid {
    padding: 28px 0 0;
}
                .resource-library.video-library.ps3-video .hcp-res .double-pan-column.second-grid .row,
                .resource-library.video-library.ps3-video .hcp-res > .row{
    margin-right: 0;
}
    .resource-library.video-library.ps3-video p.desc-body.desc-body-george {
    	font-size: 16px;
    	padding-right: 10px;
	}  
    .resource-library.video-library.ps3-video .patient-res .down-res {
    	line-height: 24px;
	}
    .resource-library.video-library.ps3-video .patient-res .pan-col-head p {
    	font-size: 16px;
	} 
    .resource-library.video-library.ps3-video .patient-res .pan-sec-col {
        padding-right: 1px;
	}                            
.skew-maroon-head.sec71bg.sec71bg1 {
    box-shadow: none!important;
    margin-left: -20px!important;
    margin-top: 20px!important;
}
.propel-efficacy .sec71bg {
    width: 97%!important;
}
.propel-efficacy p.explor-subg {
    margin-left: -2px;
}
.skew-maroon-head.last-skew-maroon-head.last-skew-maroon-head-align {
    width: 290px;
    padding: 11px 0px 11px 13px !important;
}
.skew-maroon-head-new {
    padding: 5px 16px;
    padding-right: 16px;
    }
    .propel-content .skew-maroon-head h2 {
        margin: 0px 0;
    }
        .skew-maroon-head-new h2 {
        margin: 0px 0;
    }
    .combi-therapy-header .common-headline {
        padding: 32px 25px 16px 20px;
    	min-height: 150px;
    }
    .combi-therapy-header .common-page-title {
        background-color: #B2D234 !important;
    }
    #maincontent .common-page-title p {
        font-size: 16px !important;
        line-height: 20px !important;
        font-family: Roboto-Bold !important;
        color: rgb(0, 77, 116) !important;
    	letter-spacing: -0.24px;
    }
    .combi-therapy-content .plus-img {
        top: 154px;
    }
.footnotes.footnotes1 p {
    margin-bottom: 5px;
}
    .dosing-combination .combi-therapy-content .img-blue-backgnd img {
        margin: 0 !important;
    }
    .combi-therapy-content table.table.table-dose-mod td {
        color: #004D74;
    }
    .combi-therapy-content table.table.table-dose-mod td:first-child {
        width: 48% !important;
    }
    .combi-therapy-content table.table.table-dose-mod td:nth-child(2) {
        background: transparent;
        color: #004D74;
    }
    .combi-therapy-content table.table.table-dose-mod td:nth-child(3) {
        background: transparent;
        color: #004D74;
    }
    .combi-therapy-content table.table.table-dose-mod td.green-head {
        background: #b2d234;
    }
    .combi-therapy-content table.table.table-dose-mod td.grey-head {
        background: #56849f;
        color: #fff;
    }
    .mechanism-of-action .tab-head-container .tabs-body {
        flex-direction: column;
    }
    .mechanism-of-action .tab-head-container {
        transform: none;
    }
    .mechanism-of-action .tab-heading {
        order: 1;
    }
    .mechanism-of-action .tab-head-container {
        padding-top: 0;
        text-align: center;
    }
    .mechanism-of-action .tab-head-container .tab-heading h1 {
        font-size: 24px;
        line-height: 30px;
        margin: 30px auto 20px;
        text-align: left;
    }
    .mechanism-of-action #tab-opener-1>a,
    .mechanism-of-action #tab-opener-2>a {
        font-size: 16px;
        line-height: 20px;
        max-width: 190px;
    }
    .mechanism-of-action div#nav-tab {
        display: flex;
        justify-content: center;
    }
    .mechanism-of-action #tab-opener-1>a {
        /*padding: 10px 18px 10px;*/
    	padding: 10px 3px 10px;
    }
    .mechanism-of-action #tab-opener-2>a {
        padding: 10px 22px 10px;
        margin-left: 3px;
    }
    .mechanism-of-action .tab-head-container {
        padding: 14px 18px 10px;
    }
    .mechanism-of-action .tab-head-container {
        margin-top: 0;
        padding-top: 0;
    }
    .mechanism-of-action .tab-head-container {
        background: #990064;
    }

    .nccn-guidelines  .heading-1 .heading-sub{
        font-size: 15px;
        line-height: 28px;
        text-align: left;
        display: block;
        margin-bottom: 5px;
    }
    .nccn-rec {
        /*background: #E8F1CF;*/
    	background: #f3f8e7;
        /*padding: 16px 10px 20px 10px;*/
        transform: none;
        margin-bottom: 16px;
    }
.nccn-inner .images-sec {
     width: 100%;
    /* max-width: 179px; */
    height: 191px;
    background: #E8F1CF!important;
    padding-top: 55px;
    padding-left: 22px;
    font-family: 'MyriadPro-Bold';
    font-style: italic;
    color: #004D74;
    font-size: 36px;
    line-height: 25px;
    transform: skewX(-5deg);
    margin-left: -9px;

}
.images-sec span {
    font-size: 18px!important;
    display: block;
    margin-top: 8px;
}
.image-sec.image-second {
      width: 100%;
    /* max-width: 263px; */
    height: 132px;
    background: #d7e8f6!important;
    padding-top: 41px;
    padding-left: 13px;
    font-family: 'MyriadPro-Bold';
    font-style: italic;
    color: #004D74;
    font-size: 36px;
    line-height: 25px;
    transform: skewX(-5deg);
    text-align: center;
    margin-left: -8px;
}
.image-sec.image-second span {
    font-size: 18px!important;
    display: block;
    margin-top: 8px;
}
.nccn-heads {
    font-size: 20px;
    line-height: 24px;
    font-family: 'MyriadPro-Bold';
    color: #004D74;
    padding: 13px;
}
.footnotes.nccn-heads.fn-nccn-heads.fn-nccn-heads1 {
    display: block!important;
}
.un-bold{
    font-family: 'MyriadPro-Regular';
}
    .nccn-guidelines .tab-head-container .tab-heading h1 sup {
        font-style: normal;
    }
    .nccn-inner{
        transform: none;
        display: flex;
        justify-content: center;
        align-items: center;
        margin-bottom: 17px;
    }
	.image-sec img{ max-width: 97px;}
    .content-right p {
        margin-bottom: 5px;
    }
    .footnotes p {
        color: #333333;
        font-size: 9.75px;
        line-height: 11px;
        margin-bottom: 0;
    	margin-left:10px;
    }
    
    .nccn-mono.container-center {
        display: none;
    }
    .image-sec {
        flex-basis: 40%;
        padding-right: 8px;
    }
    .nccn-head {
        font-size: 20px;
        line-height: 24px;
        font-family: 'MyriadPro-Bold' !important;
        color:#004D74;
    }
    .nccn-txt {
        /*font-size:6px;*/
    	font-size: 18px;
        line-height: 20px;
        color: #333333;
        font-family: 'MyriadPro-Regular';
    	    margin-bottom: 33px;

    }
.nccn-txt-nw{
padding: 0px 10px 0px 10px;
        margin-bottom: 13px;
}
p.nccn-txt.nccn-heads {
    margin-bottom: 0px;
}
	.footnotes p:last-child {
    	text-indent: -5px;
	}
.footnotes.nccn-heads.fn-nccn-heads p {
    margin-left: 1px;
}
.patient-profiles #tab-opener-1 > a {
   padding: 10px 7px 10px;
}
	.monotherapy3.profound .secondary_endpointOS.Primary_endpoint {
    	margin-top: 34px;
        padding-top: 0 !important;
	}
.patient-profiles .tab-opener-11 > a {
    padding: 10px 3px 10px!important;
}
.ps3-video .patient-res.resources-padding-lt {
    padding: 27px 20px 0px 20px!important;
}
}

.propel-content .heading .bold {
    font-family: "Roboto-Bold" !important;
}

@media (max-width: 1003px) {
    .mechanism-of-action .tab-head-container {
        margin-top: -1px;
        margin-bottom: 27px;    
    }
    .outside-rep-section {
       background: #006699;
        top: 265px;
     }

        .combination-therapy.dosing-combination #maincontent {
        margin-top:91px !important;
    }
	.isi-body .indications {
    	margin-bottom: 22px !important;
	}
	.ps3 .isi-body .indications h2:not(:first-child) {
    	letter-spacing: 0;
    }
.mob-container .pro-submenu .common-container {
    height: 389px;
}
}


@media (min-width: 1004px) {
	.isi-tray .isi-tray-head h2 {
    	/*max-width: 1018px; */
    	max-width: 1025px;
    	margin-bottom: 7px;
	}
    .isi .isi-body .left-isi-cont {
    	padding-left: 15px !important;
    	padding-right: 6.5px !important;
	}
	.isi .isi-body .right-isi-cont {
    	padding-right: 15px !important;
    	padding-left: 6.5px !important;
	}
	#header .indication-selector .header-dropdown ul li.init span.child-inner> span.nowrap{
		font-family: "Roboto-Regular";
    	font-size: 14px;
	}
	.navbar.navbar-default.container{
    	padding-left: 5px;
    	padding-right: 10px;
	}
	.fullnavigation .navbar-default .navbar-nav>li > a:hover {
    	color: #FFFFFF;
    	border-bottom: 5px solid #FFFFFF;
    	font-weight: normal;
	}
	.fullnavigation .navbar li ul.multi-level li > a, .fullnavigation .navbar li ul.multi-level li > a {
    	padding: 10px 10px 0px 15px !important;
	}
	.fullnavigation .navbar li ul.multi-level > li:nth-child(2) a, .fullnavigation .navbar li.about-lynparza ul.multi-level li:last-child > a, .fullnavigation .navbar li.resource-library ul.multi-level li:last-child > a {
    	padding-bottom: 10px !important;
	}
	/*.fullnavigation .navbar li.efficacy ul.multi-level li > a, .fullnavigation .navbar li.safety-tolerability ul.multi-level li > a, .fullnavigation .navbar li.resource-library ul.multi-level li:last-child > a{
    	padding-bottom: 10px !important;
    	padding-top: 0px!important;
	}*/
	li.resource-library ul.multi-level li:last-child, li.about-lynparza ul.multi-level li:last-child {
    	border-radius: 0 0 10px 10px;
	}
	.fullnavigation .navbar li.about-lynparza ul.multi-level li:nth-child(2) > a{
    	/*padding-bottom: 0px !important;*/
	}
	/*.fullnavigation .navbar li.resource-library ul.multi-level li:nth-child(2) > a {
    	padding-bottom: 0px !important;
	}*/
    .fullnavigation li.about-lynparza ul.dropdown-menu.multi-level li:last-child, .fullnavigation li.resource-library ul.dropdown-menu.multi-level li:last-child {
        box-shadow: none !important;
    }
	.dosing-mono-3 main {
    	xmargin-top: 130px !important;
	}
	.fullnavigation {
    	box-shadow: 0px 3px 6px #0000004D;
	}
	/*ul.dropdown-menu.multi-level li:first-child {
    	box-shadow: 0px 0px 6px #0000004D;
	}*/
    .fullnavigation .navbar li ul {
        background-color: #990064;
    	min-width: fit-content;
    }
	.fullnavigation ul.dropdown-menu.multi-level li:nth-last-child(2), li.resource-library ul.multi-level li:last-child, li.about-lynparza ul.multi-level li:last-child {
    	box-shadow: none;
	}
}
@media screen and (min-width: 1004px) and (max-width: 1040px){
	.dosing-combination .footnote{
	    padding-left: 10px;
	}
}
@media screen and (min-width: 1004px) and (max-width: 1365px){
	.ps3 .isi-tray .isi-tray-head h2 {
   		/* max-width: 985px;
    	padding: 0 130px 0 45px;*/
   		max-width: 836px;
	}
}
@media (min-width:992px) and (max-width: 1024px) and (orientation : landscape) {
	.patient-profiles .pat-detail h4{
    	padding-right: 86px;
	}
}  
 @media (min-width:1024px) and (max-width: 1024px){
p.image-after em:after {
    right: 7.7%!important;
}
  p.image-after:after {
    right: 4.7%!important;
}
    h1.container-center.container-centers1.container-centers-left {
    margin-left: 0px;
}
}
/* 18-04-23 */   
.end-eff-cont-os {
    font-size: 16px;
    font-family: 'Roboto-Bold';
    color: #525252;
    padding-top: 25px; 
    margin-bottom: 0px;
}
.brca-subgrp {
    font-size: 16px;
    font-family: 'Roboto-Bold';
    color: #004D74;
    margin-bottom: 1px;
}
.events-txt {
    font-size: 16px;
    font-family: 'Roboto-Bold';
    color : #525252;
}


/* 18-04-23 */ 
/* ==========================XXXXXXXXXXXXXXXXXXXXXXX=========================== */

@media (min-width:375px) and (max-width: 467px){
	.Primary_endpoint-text-blue31 {
   		padding-right: 14px;
	}
	.profound.efficacy.monotherapy3 .Primary_endpoint.section-78 .container-center .pink78-pg {
    	padding-right: 0px;
	}
}
/*************Common and new style class***************/
.top_0 {
    padding-top: 0;
}        
.top_10 {
    padding-top: 10px;
}
.top_20 {
    padding-top: 20px;
}
.mtop_0 {
    margin-top: 0;
}
.mtop_10 {
    margin-top: 10px;
}
.mtop_20 {
    margin-top: 20px;
}
.mtop_40 {
    margin-top: 40px;
}
.mtop_50 {
    margin-top: 50px;
}
.bottom_0 {
    padding-bottom: 0px;
}
.mleft_0 {
    margin-left: 0px;
}
.bottom_5 {
    padding-bottom: 5px;
}
.bottom_10 {
    padding-bottom: 10px;
}
.bottom_20 {
    padding-bottom: 20px;
} 
.mbottom_0 {
    margin-bottom: 0px;
}
.mbottom_5 {
    margin-bottom: 5px;
}
.mbottom_10 {
    margin-bottom: 10px;
}
.mbottom_20 {
    margin-bottom: 20px;
}
.indent3 {
    margin-left: 3px;
}
.ast-footnote {
    margin-left: -7px;
}
.single-footnote {
    margin-left: -5px;
}
.double-footnote {
    margin-left: -7px;
}
.break-all {
    word-break: break-all;
}
.ff-rblack {
    font-family: 'Roboto-Black';
    font-style: normal;
}
.ff-rregular{
    font-family: 'Roboto-Regular';
}
.ff-rbold{
    font-family: 'Roboto-Bold' !important;
}
.fs-normal {
    font-style: normal !important;

}    
.blue-subhead1 {
    font-family: 'Roboto-Bold';
	font-size: 20px;
    line-height: 22px;  
    color: #004D74;        
} 
.ef-below-gragh-block {
    margin-top: 20px;
}        
.ef-below-gragh-block div {
    margin-bottom: 20px;
}    
.ef-below-gragh-block p {
    font-family: 'Roboto-Regular';
	font-size: 16px;
    line-height: 20px;  
    color: #000000;    
    margin-bottom: 0;  
    margin-top: 5px;
} 
.ef-below-gragh-block p b {
    font-family: 'Roboto-Bold';
}
.ef-below-gragh-block p.last-note {
	font-size: 10px;
    line-height: 12px; 
    margin-top: 5px;
} 
h3.center-heading {
    font-family: 'Roboto-Bold';
    text-align: center;
    font-size: 20px;
    line-height: 24px;
    max-width: 674px;
    margin: -10px auto 30px;
}
p.image-after:after {
    display: none;
}
a.here-link {
    padding-right: 15px;
    position: relative;
}
p.image-after em:after {
    right: 0px !important;
    top: 1px;
}
p.new-eyebrow {
    line-height: 28px;
    font-size: 16px;
    margin-bottom: 0;
}
@media only screen and (min-width: 1351px) {
	.patient-profiles.lynparzahcpprostrate .combi-patient-profile .joe-history {
    	height: 533px;
	}
}
@media only screen and (max-width: 1003px) { 
	a.here-link {
    	padding-right: 15px;
	}
}  
@media only screen and (min-width: 768px) { 
.nccn-guidelines.lynparzahcpprostrate .nccn-mono.container-center {
    display: block !important;
}
}
@media only screen and (min-width: 768px) and  (max-width: 991px) { 
	.footnote-below-landong {
    	margin: 10px 20px 0;
	}
}
@media only screen and (max-width: 767px) {        
	.blue-subhead1 {
		font-size: 16px;
    	line-height: 20px; 
        margin-bottom: -10px;    
	} 
    h3.center-heading {
    	line-height: 26px;
        margin: 10px auto 0;    
	}  
    p.new-eyebrow {
    	line-height: 20px;
        margin-bottom: 5px;
	}  
    .nccn-guidelines .nccn-mono .footnotes p:last-child {
		text-indent: -4px;
    }
    .nccn-guidelines .ncci-combi .footnotes p:last-child {
         text-indent: 0;
     }
}
@media only screen and (max-width: 574px) { 
    .ps3 #header .ribbon img {
        width: 96%;
    }
}
@media only screen and (min-width: 462px) and  (max-width: 481px) {     
	p.image-after {
    	padding-right: 20px;
	}
    p.image-after em:after {
    	top: 21px;
	}    
}
@media only screen and (max-width: 461px) {     
	p.image-after em:after {
    	top: 22px;
	}
}
@media only screen and (min-width: 1920px) and  (max-width: 1920px) { 
h1.container-center.container-centers1.container-centers-left {
    padding-left: 18px;
}
}
@media only screen and (min-width: 993px) and  (max-width: 1350px) { 
h1.container-center.container-centers1.container-centers-left {
    margin-left: 0px;
}
    .ps3-mono-testing h1.container-center.container-centers1.container-centers-left {
    margin-left: auto;
}
}
@media (min-width: 1365px) {
.combi-patient-profile .medical-hist.desktop.col-xs-12.col-sm-6 {
    width: 53%;
}
}
@media (width: 992px) {
.home.ps3 .approved-callout.mobile {
    display: none !important;
}
.home.ps3 .approved-callout.desktop, .homepg-callout.desktop.desk-callout {
		display:block !important;
	}
}
/******month violater style starts here******  
.bcam-bg.container {
    background: #55BDDF;
	position: absolute;
    top: 131px;
}

.bcam-content.container-center {
    width: 100%;
    font-size: 16px;
    color: #fff;
    font-family: 'Roboto-Regular';
    margin: 0 auto;
    padding: 0;
}

.bcam-content .ribbontxt a {
    font-size: 16px;
    color: #fff;
    font-family: 'Roboto-Regular';
    text-decoration: underline;
}
.bcam-content .ribbon {
    margin-left: 32px;
    margin-right: 20px;
    display: inline-block;
}
.home.ps3 main#maincontent {
    margin-top: 192px !important;
}
@media (max-width: 1003px) {
    .bcam-bg .bcam-content .ribbontxt {
        font-size: 13px;
        text-align: center;
        position: relative;
        margin-left: 0px;
        width: 100%;
        display: block;
        padding: 10px 0;
    }
    .bcam-content.container-center {
        padding: 0;
    }    
    .bcam-content .ribbon {
        position: absolute;
        opacity: 0.3;
    }
    .bcam-bg .bcam-content .ribbontxt {
        display: block;
        padding: 10px;
    }
    .bcam-content .ribbontxt a {
        font-size: 14px;
    }
	.home.ps3 main#maincontent {
    	margin-top: 151px !important;
	}
	.bcam-bg.container {
    	top: 92px;
	}

}
@media only screen and (min-width: 768px) and  (max-width: 1003px) {
        .ps3 #header .ribbon img {
        width: 65%;
    }
}
@media only screen and (min-width: 603px) and  (max-width: 767px) {
    .home.ps3 main#maincontent {
    	margin-top: 132px !important;
	}
}

@media only screen and (min-width: 768px) and  (max-width: 1003px) {
    .home.ps3 main#maincontent {
    	margin-top: 128px !important;
	}
}
@media only screen and (min-width: 1004px) and  (max-width: 1265px) {
	#header .indication-selector .header-dropdown ul li.init span.child-inner {
    	padding: 0 5px 0 11px;
	} 
}                
/******month violater style ends here*******/