/*.isi-tray {
	display: none !important;
}*/
.brca-testing p.when-ico-head {
    margin-bottom: 28px;
}
.ref-foot .footnote{
    font-size: 12px !important;
    margin-bottom: 10px;
    font-family: 'Roboto-Regular';
}
span.footnote_fda.indent, span.footnote_fda.indent sup {
font-family: 'Roboto-Light';
font-size: 16px;
color: #000;
}
.study_design sup.new-sup-color {
color: #000 !important;
font-family: 'Roboto-Light';
}

.indent {
text-indent: -6px;
}

.double_indent {
text-indent: -9px;
}

.home .recommend_content .indent {
margin-top: 0%;
}

.efficacy .footnote_sub {
font-family: 'Roboto-light';
}

.home_indication h2 {
font-family: "Roboto-Bold";
color: #004D74;
margin: 0 0 10px 0;
font-size: 18px;
}

.brca_space {
padding-left: 2px;
}

.home .yellow_eyebrow sup {
font-family: 'Roboto-Regular';
}

.align_center {
text-align: center;
}

.landing-hero {
background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-pan/home/hero.png);
background-repeat: no-repeat;
background-position: center;
background-size: cover;
display: block;
padding: 4%;
}

.callouts {
margin-bottom: 6%;
}

.callouts a {
color: #004D74;
text-decoration: none;
}

.callouts a .callout_span {
text-decoration: underline;
font-family: Roboto-Medium;
}

.callout {
width: 30%;
margin-left: 69%;
margin-top: 20px;
text-align: center;
display: block;
background-color: #FCC50B;
transform: skewX(-10deg);
box-shadow: 5px 5px rgba(252, 197, 11, .4);
-webkit-box-shadow: 5px 5px rgba(252, 197, 11, .4);
border: solid 3px #FCC50B;
padding: 1%;
font-family: Roboto-Bold;
font-size: 16px;
}

.callout p,
.callouts a span {
transform: skewX(+10deg);
}

.home_eyebrow {
background: #FFFFFF 0% 0% no-repeat padding-box;
text-align: center;
padding: 1% 0%;
color: #004D74;
font-family: 'Roboto-Regular';
font-size: 16px;
line-height: 23px;
}

.home_eyebrow span:nth-child(1) {
font-family: 'Roboto-Bold';
}

.recommend_content .home_footnote {
padding-left: 13%;
color: #000;
}

.recommend_content .home_footnote.home_footnote_left {
padding-left: 0;
}

.yellow_eyebrow {
background: #FCC50B 0% 0% no-repeat padding-box;
text-align: left;
padding: 1%;
color: #004D74;
font-size: 24px;
margin-top: -1px;
font-family: 'Roboto-Bold';
padding-top: 42px;
padding-bottom: 42px;
}

.yellow_eyebrow h4 {
font-size: 18px;
margin-bottom: 7px;
}

.home_footnote {
font-family: 'Roboto-Light';
margin-top: 1%;
font-size: 14px;
}

.treatment_paradigm .home_footnote {
margin-top: 1.5%;
}

.home_footnote .footnote_fda {
font-size: 16px;
}

.home_footnote .footnote_abb {
margin-top: 1%;
font-size: 14px;
}

sup.brca_space.one {
padding-left: 5px;
}

.recommend_content {
color: #004D74;
margin-top: 3%;
}

.nccn_clinical {
font-size: 18px;
font-family: 'Roboto-Bold';
padding-left: 13%;
}

div#study_height {
padding-top: 3%;
}

.olaprib_cat {
font-family: 'Roboto-Regular';
font-size: 16px;
padding-left: 14%;
}

.mpac_management {
font-size: 23px;
font-family: 'Roboto-Bold';
color: #fff;
}


/*home*/


/*treatment_paradigm*/

.treatment_paradigm .recommend img {
/*padding-top: 2.25%;*/
padding-top: 1%;
position: relative;
transform: skewX(+10deg);
left: -7%;
}

.recommend_bullet,
.recommend_platinum {
font-family: 'Roboto-Bold';
font-size: 16px;
}

.recommend_bullet {
padding-left: 15%;
transform: skewX(+10deg);
}

ul.recommend_bullet {
list-style: none;
padding-left: 0px;
}

ul.recommend_bullet li {
font-family: 'Roboto-Bold';
font-size: 16px;
line-height: 20px;
}

ul.recommend_bullet li:before {
content: "\2022";
font-size: 16px;
padding-right: 10px;
top: 3px;
position: relative;
}

.recommend_based {
padding-left: 10%;
transform: skewX(+10deg);
}

.recommend_platinum {
margin-top: 20px;
display: block;
/*background-color: #004D741A;*/
background-color: #e5edf1;
transform: skewX(-10deg);
-ms-transform: skewX(-10deg);
margin-left: 5%;
padding: 1.4%;
}

.platinum_chart img {
width: 100%
}

.flex_container.container-center.desktop {
padding: 2% 1% 1%;
display: flex !important;
}

.flex_content {
color: #004D74;
font-size: 16px;
font-family: 'Roboto-Bold';
}

.flex_one,
.flex_two,
.flex_three {
flex: 1;
}

.flex_one .flex_content,
.flex_two .flex_content,
.flex_three .flex_content {
margin: 1% 16% 4% 4%;
}

.flex_container img {
margin-right: 2%;
}

.yellow_eyebrow p, .yellow_eyebrow h1 {
font-family: 'Roboto-Regular';
font-size: 20px;
text-align: left;
}

.treatment_paradigm .yellow_eyebrow p,
.treatment_paradigm .yellow_eyebrow h1,
.efficacy .yellow_eyebrow p,
.efficacy .yellow_eyebrow h1,
.BRCA-Testing .yellow_eyebrow p,
.BRCA-Testing .yellow_eyebrow h1 {
line-height: 22px;
margin-bottom: 15px;
padding-right: 10%;
}

.yellow_eyebrow h2, .yellow_eyebrow.safety h1 {
    font-family: inherit;
    font-size: 30px;
    text-align: left;
    font-weight: bolder;
}

.dosing-page .yellow_eyebrow {
padding-top: 50px;
}


}
.moa-page span.font-normal {
font-style: initial;
}
/* .yellow_eyebrow h1 {
    margin: 0;
    font-size: 30px;
    font-family: 'Roboto-Bold';
    line-height: 35px;
    color: #004D74;
} */
.home .yellow_eyebrow h2, .home .yellow_eyebrow.safety h1  {
text-align: center;
font-size: 25px;
}
.home .yellow_eyebrow {
padding-top: 10px;
padding-bottom: 10px;
}
.nccn_guidelines {
color: #004D74;
font-size: 18px;
font-family: 'Roboto-Bold';
margin-top: 1.4%;
text-align: center;
}

/*treatment_paradigm*/
.study_design {
color: #004D74;
font-size: 20px;
}
.study_design .study_design_heading {
	font-family: 'Roboto-Bold';
    margin: 4px 0px;
}
.study_design_heading {
font-size: 25px;
}
.study_design .study_design_subheading {
font-family: 'Roboto-Medium';
}
.study_design .main {
font-size: 25px;
}
.efficacy .study_design_description {
padding-left: 19px;
}
.efficacy .median {
padding-left: 0px;
}
img.progress_img.img-wid.container-center {
max-width: 800px;
padding-bottom: 17px;
}
img.progress_img.head.container-center {
max-width: 900px;
}
.efficacy .study_design_heading.trial-sub {
margin-bottom: 2.5%;
}
.effi_footnote.kaplan.analyses.container-center {
margin-bottom: 44px;
}
li.patient-had {
margin-bottom: 20px;
}
.effi_footnote.kaplan.container-center {
padding-bottom: 2%;
padding-left: 10px;
padding-right: 10px;
font-family: roboto-medium;
font-size: 17px;
}
.efficacy .study_design_subheading.trial-sub {
margin-bottom: 2%;
}
.study_design.container-center.end-space {
margin-bottom: 47px;
}
.study_design_description {
font-size: 16px;
color: #000000;
margin-top: 10px;
margin-bottom: 2%;
}
.efficacy .flex_one .flex_content {
margin: 4% 32% 7% 7%;
padding-left: 21%;
}
.prognastic {
background-color: #E5EDF0;
}
.prognastic.ae {
background: none;
}
.prognastic.lab {
padding-bottom: 40px;
}
.prognastic .desktop {
width: 100%
}
.progress_img {
width: 100%;
display: block;
margin-left: auto;
margin-right: auto;
max-width: 608px;
padding-bottom: 1%;
}
.progress_bg {
background-color: #E5EDF0;
}
.prognastic .study_design {
padding-top: 4%;
padding-bottom: 4%;
}
.efficacy .prognastic .study_design {
padding-top: 2%;
padding-bottom: 1%;
}
.prognastic .study_design .study_design_subheading {
font-family: 'Roboto-medium';
font-size: 20px;
margin-top: -1%;
}
.footnote_sub {
padding-bottom: 3%;
}
.recommend_content.container-center img {
width: 100%;
max-width: 110px;
}
.study_design_heading.adverse,
.study_design_subheading.adverse {
text-align: center;
}
.home_footnote.container-center.nccn {
margin-left: 36px;
}
.moa span.font-normal {
font-style: initial;
position: relative;
left: 2px;
}
.prognastic .study_design .study_design_description {
font-family: 'Roboto-regular';
font-size: 16px;
}
.prognastic .study_design .study_design_description {
list-style: none;
padding: 0;
}
.prognastic.os-polo .study_design {
padding-bottom: 25px;
}
img.progress_img.head.next.container-center {
margin-top: -2px;
}
li.hris {
margin-bottom: 10px;
margin-top: 12px;
}
img.progress_img.head.next.container-center {
margin-top: -2px;
padding-bottom: 35px;
}
.efficacy .flex_container {
padding-left: 1%;
margin-top: 40px;
display: flex;
margin-bottom: 2%;
}
.efficacy .bottom_space {
padding-bottom: 30px;
}
.treatment_paradigm .flex_one .flex_content,
.treatment_paradigm .flex_two .flex_content,
.treatment_paradigm .flex_three .flex_content {
margin: 4%;
}
.efficacy .two .flex_two {
padding-left: 0%;
}
.efficacy .polo_left_align {
padding-left: 10px;
}
.efficacy .two .flex_two img,
.efficacy .two .flex_one img {
width: 85%;
margin-bottom: 1%;
}
.study_design_description p:last-child {
margin-bottom: 43px;
}
.prognastic .study_design .study_design_subheading.for {
margin-top: 0%;
}
img.progress_img.bar.container-center {
padding-top: 5px;
padding-bottom: 16px;
}
.study_design_description p {
color: #004D74;
margin-bottom: 10px;
}
.safety-tolerability .home_footnote {
margin-top: 8px;
margin-bottom: 3.5%;
line-height: 13px;
}
#resctionchart {
max-width: 1021px;
}
img#parameter {
padding-bottom: 0;
}
#parameter {
max-width: 1083px;
}
.home_footnote.second-foot.container-center p:last-child {
margin-bottom: 0;
}
.home_footnote.second-foot.container-center {
margin-bottom: 0;
margin-top: -12px;
}
.efficacy .yellow_eyebrow {
/* margin-bottom: 2%;*/
}
.efficacy .prognastic img {
padding-bottom: 12px;
}
.efficacy .study_design_heading {
margin-top: 1%;
margin-bottom: 10px;
line-height: 30px;
}
.orr .study_design_subheading {
line-height: 26px;
margin-bottom: 20px;
font-size: 20px;
}
.efficacy .os-polo .study_design_heading {
margin-top: -1%;
}
.effi_footnote,
.effi_footnote_sub {
font-family: 'Roboto-Light';
margin-top: 0;
font-size: 14px;
padding: 0;
padding-bottom: 6%;
}

.study_design.container-center.bottom_space .effi_footnote {
padding: 0;
color: #000;
}

.effi_footnote.kaplan-meier {
padding-left: 12px;
font-family: 'Roboto-Regular';
color: #000 !important;
}
.effi_footnote_sub {
font-family: 'Roboto-Regular';
font-size: 16px;
}
.effi_body {
margin: 15px 0;
font-size: 16px;
padding: 0;
}
.study_design.container-center.end-space .study_design_subheading {
font-family: 'Roboto-Bold';
}
.effi_footnote.polo {
margin-top: 4%;
}
.effi_footnote_sub {
padding-bottom: 6%
}
.efficacy .progress_img {
/*padding-bottom: 3%;*/

padding-top: 2%;
margin-top: 0%;
}
.efficacy .orr_flag {
padding-top: 3%;
}
.orr .study_design_description {
padding-left: 0%;
line-height: 20px;
}
.median .study_design_heading {
margin-top: 5%;
}
.os-polo {
padding-top: 3% !important;
padding-bottom: 2% !important;
}

/*MOA*/
.common-headline {
background: #FCC50B;
padding: 40px 0;
}
.common-headline h1 {
margin: 0;
font-size: 30px;
font-family: 'Roboto-Bold';
line-height: 35px;
font-style: italic;
color: #004D74;
}
.common-headline h2 {
font-family: 'Roboto-Medium';
font-size: 20px;
font-weight: normal;
color: #ffffff;
}
.carousel-container h2 {
font-family: 'Roboto-Medium';
font-size: 20px;
text-align: center;
margin: 0;
font-weight: normal;
}
.carousel-container {
padding: 50px 0 70px 0;
}
.moa-page .carousel-container .carousel-block {
position: relative;
width: 100%;
background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-pan/moa/d_moa_large_angled_blue.png);
background-position: center;
background-repeat: no-repeat;
}
.moa-page .carousel-container .carousel-block .carousel {
width: 800px;
height: 237px;
margin: 35px auto 0 auto;
position: static;
}
.moa-page .carousel-container .carousel-block .carousel-indicators {
width: 100%;
top: 243px;
left: 0%;
margin: 0;
padding: 0;
}
.moa-page .carousel-container .carousel-block .carousel-indicators li {
width: 275px;
background-color: #f0f0f0;
margin: 0;
margin-right: 20px;
border-radius: 0;
height: 7px;
border: none;
}
.moa-page .carousel-container .carousel-block .carousel-indicators li.active {
background-color: #004d74;
}
.moa-page .carousel-container .carousel-block .carousel-inner .item {
height: 100%;
}
.moa-page .carousel-container .carousel-block .carousel-inner .item .left-content {
width: 30%;
display: inline-block;
}
.moa-page .carousel-container .carousel-block .carousel-inner .item .left-content img {
margin: 35px 25px;
}
.moa-page .carousel-container .carousel-block .carousel-inner .item .right-content {
display: inline-block;
width: 68%;
vertical-align: middle;
}
.moa-page .carousel-container .carousel-block .carousel-inner .item .right-content p {
color: #ffffff;
font-family: 'Roboto-Regular';
font-size: 20px;
line-height: 25px;
margin-bottom: 0;
}
.moa-page .carousel-container .carousel-block .carousel-control.left {
background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-pan/moa/d_global_left_arrow_on.png);
left: 10px;
position: absolute;
}
.moa-page .carousel-container .carousel-block .carousel-control.right {
background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-pan/moa/d_global_right_arrow_on.png);
right: 10px;
position: absolute;
}
.moa-page .carousel-container .carousel-block .carousel-control {
background: transparent;
background-repeat: no-repeat;
background-position: center;
width: 50px;
height: 85px;
top: 66px;
opacity: 1;
}
.moa-page .carousel-container .carousel-block .carousel-control.left.disable {
background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-pan/moa/d_global_left_arrow_off.png);
pointer-events: none;
position: absolute;
}
.moa-page .carousel-container .carousel-block .carousel-control.right.disable {
background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-pan/moa/d_global_right_arrow_off.png);
pointer-events: none;
position: absolute;
}
.moa-page .carousel-container .carousel-mobile {
display: none;
}
.moa-page p.footnote.new {
font-size: 16px !important;
line-height: 20px !important;
}
.moa-page .moa-bottom-content.new {
margin-top: 35px;
}
.common-tagging {
background: #004D74;
text-align: center;
padding-top: 10px;
padding-bottom: 15px;
}
.moa-page p.footnote.new {
font-size: 16px !important;
line-height: 20px !important;
font-family: 'Roboto-Medium';
}
.footnote.bannerfootnote {
margin-bottom: 25px;
margin-top: -38px;
margin-left: 10px;
}
.moa-page .common-tagging+.footnote-content {
margin-top: 35px;
}
.common-tagging.see-efficacy a {
color: #004D74
}
.common-tagging a {
display: inline-block;
width: 750px;
padding-top: 5px;
padding-bottom: 5px;
color: #ffffff;
text-decoration: none;
font-family: 'Roboto-Medium';
font-size: 20px;
line-height: 25px;
transform: skewX(-10deg);
background-color: #f7941f;
box-shadow: 5px 5px rgba(247, 148, 31, .5);
-webkit-box-shadow: 5px 5px rgba(247, 148, 31, .5);
border: solid 3px #f7941f;
max-width: 100%;
}
.common-tagging a span {
transform: skewX(10deg);
display: block;
}
.footnote {
font-family: 'Roboto-Light';
font-size: 14px !important;
color: #000000 !important;
line-height: 17px;
margin-bottom: 0;
}

/*US-63388 changes 25-06-22*/
.home_footnote .footnote-acronym {
font-family: 'Roboto-Regular';
font-size: 12px !important;
color: #000000 !important;
line-height: 17px;
}
.asco-metastatic {
padding: 54px 0;
background-color: #e9e8cd;
margin: 22px 0 32px 0;
}
.asco-brca {
display: flex;
max-width: 1024px;
margin: auto;
padding-left: 20px;
align-items: center;
}
.text-asco p {
margin-top: -106px;
font-size: 28px;
font-weight: 900;
color: #004D74;
}
.metastatic-text {
padding-left: 25px;
}
.metastatic-text .bold-text {
letter-spacing: 0px;
color: #004D74;
opacity: 1;
font-family: roboto-bold;
font-size: 19px;
line-height: 26px;
margin-bottom: 5px;
 margin-top: 0px;
}
.metastatic-text .normalt {
font-size: 16px;
margin-bottom: 0;
}
.metastatic-text ul {
padding-left: 10px
}

.home #maincontent > div.maincontent.parsys > div:nth-child(2) > div > div:nth-child(2) > nobr {
    white-space: normal;
}

@media (max-width: 767px) {
p.normalt.nw-p {
    margin-top: 0 !important;
}

.moa-page .carousel-container {
    padding: 35px 30px 20px 30px;
}

.moa-page .common-tagging {
    padding-top: 0;
    padding-bottom: 0;
}

.moa-page .moa-bottom-content {
    padding-bottom: 30px;
}

.common-headline {
    padding: 60px 20px 40px 20px;
}
/*US-63388 changes 25-06-22*/

.moa-page .home_footnote .footnote-acronym {
    padding-left: 0;
    margin-bottom: 39px;
}

.home_footnote .footnote-acronym {
    padding-left: 10px;
    margin-bottom: 35px;
}

body.polo.olaparib-efficacy.efficacy .home_footnote .footnote-acronym {
    padding-left: 10px;
}

.asco-brca {
    display: block;
    padding-right: 20px;
}

.text-asco p {
    margin-top: 0;
}

.metastatic-text {
    padding-left: 0
}
}

/*MOA*/

/*brca*/
.blue_bg {
margin-top: 20px;
display: block;
padding: 1%;
height: 112px;
width: 98%;
background: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-pan/brca/why-flag.svg) no-repeat;
}
.blue_bg img {
padding-left: 4%;
margin-top: 11px;
}
.brca_flex_one .blue_bg img {
padding-left: 1.6%;
margin-top: 1px;
}
.brca_content_bg {
margin-top: -100px;
display: block;
background-color: #fff;
border: solid 3px #fff;
padding: 1%;
width: 84%;
margin-left: 14%;
}
sup.font-normal {
font-style: initial;
}
.brca_content_bg .flex_content {
padding-left: 0%;
padding-right: 15%;
}
.brca_flex_two .blue_bg img {
padding-left: 25px;
margin-top: 12px;
}
.BRCA-Testing .recommend {
padding-top: 2%;
padding-bottom: 4.4%;
}
.BRCA-Testing .recommend img {
padding-top: 8%;
/*width: 11%;*/

z-index: 1;
position: relative;
}
.BRCA-Testing .recommend_platinum {
background-color: #fff;
padding: 3%;
}

/*.BRCA-Testing .home_footnote {
padding-bottom: 3%;
padding-top: 3%;
}*/
.BRCA-Testing .recommend_based {
color: #004D74;
font-size: 25px;
font-family: Roboto-Bold;
margin-top: 0px;
}
.BRCA-Testing .recommend_bullet {
color: #004D74;
font-size: 16px;
font-family: Roboto-Regular;
padding-left: 8%;
}

/*.BRCA-Testing .home_footnote {
padding: 3% 0 4% 0;
}*/
.BRCA-Testing .recommend_based {
padding-left: 7%;
}
#brcafoot {
padding: 0;
text-align: center;
}
.flex_heading {
font-size: 25px;
}
.flex_subheading {
font-size: 16px;
margin-bottom: 4px;
}
.BRCA-Testing .flex_content ul {
font-size: 16px;
font-family: Roboto-Regular;
color: #000;
margin-left: -2%;
}
.BRCA-Testing .flex_content ul .blue-bold {
font-family: Roboto-Bold;
color: #004D74;
}
.BRCA-Testing .flex_footnote {
font-size: 14px;
font-family: Roboto-light;
color: #000;
margin-left: 2%;
}
.flex_container_brca {
padding-top: 28px;
padding-left: 20px;
}
.BRCA-Testing .recommend_platinum {
width: 94%;
}

/*brca*/

/*efficacy*/
.flex_container_two .flex_two_one .flex_content{
margin-top: 25px;
padding: 0 75px;
}
.flex_container_two .flex_two_two .flex_content{
margin-top: 25px;
}
.flex_container_two .flex_two_three .flex_content{
margin-top: 0;
    padding: 15px 20px 0;
}
.flex_container_two .flex_two_three img{
padding-top: 50px;
}
.flex_container_two .flex_two_two img{
padding-top: 20px;
}
.green-next {
margin-top: -50px;
}
.flex_container_two {
display: flex;
align-items: center;
}
.flex_two_one,
.flex_two_two,
.flex_two_three {
display: flex;
flex-direction: column;
align-items: center;
    text-align: center;
flex: 1;
margin: 0 0 20px 0;
}
.flex_container_two .flex_content {
margin: 0 0 0 10px;
}
.brca_content_bg .flex_content .flex_heading {
/* margin-bottom: 0px; */
    margin-bottom: 5px;
    margin-top: 4px;
}

/*efficacy*/
@media (max-width: 1023px) {
.brca_flex_three .blue_bg img {
    margin-top: 14.5px!important;
}

.brca_flex_two .blue_bg img {
    padding-left: 0% !important;
    padding-top: 0.75px!important;
}

#brcafoot {
    padding-left: 3% !important;
}

.recommend_content .home_footnote {
    padding-left: 17%;
}

.nccn_clinical,
.olaprib_cat {
    padding-left: 17%;
}

.moa-page .carousel-container .carousel-desktop {
    display: none;
}

.moa-page .carousel-container {
    padding: 35px 30px;
    background-color: #e5edf1;
}

.moa-page .carousel-container .carousel-mobile {
    display: block;
    text-align: center;
}

.moa-page .carousel-container .carousel-mobile p {
    font-family: 'Roboto-Regular';
    font-size: 15px;
}

.moa-page .carousel-container .carousel-mobile .carousel-item {
    margin: 10px auto 0 auto;
}

.moa-page .carousel-container .carousel-mobile .carousel-item img {
    margin: 15px auto;
    display: block;
}

.moa-page .carousel-container .carousel-mobile .carousel-item img:first-child {
    width: 14px;
}

.moa-page .moa-bottom-content {
    background-color: #e5edf1;
    padding-bottom: 40px;
}

.BRCA-Testing .recommend img {
    padding-top: 14% !important;
}

BRCA-Testing .recommend_based {
    padding-left: 9% !important;
    font-size: 24px !important;
}

.BRCA-Testing .recommend_bullet {
    padding-left: 10% !important;
}

.progress_img {
    max-width: 100%;
}
}
.test-patient-brca {
display: flex;
max-width: 1024px;
margin: auto;
padding-left: 20px;
align-items: center;
}
.test-patient-wrap {
padding: 54px 0;
/*background: #004D741A;*/

background-color: #e5edf1;
margin: 22px 0 32px 0;
}
.brcanalysis-text {
padding-left: 13px;
}
.brcanalysis-text p.bold-text {
letter-spacing: 0px;
color: #004D74;
opacity: 1;
font-family: roboto-bold;
font-size: 19px;
line-height: 26px;
margin-bottom: 5px;
}
.brcanalysis-text p.normalt {
font-size: 16px;
margin-bottom: 0;
}

/*compatability test 2*/
@media only screen and (min-width:2000px) {
    .home .landing-hero {
	padding: 6% 4%;
	}
}
/*End compatability test 2*/


@media only screen and (max-width:1023px) and (min-width:768px) {
.brcanalysis-text {
    padding-right: 20px;
}

.BRCA-Testing p.recommend_bullet.blackf {
    color: #000;
    padding-left: 80px !important;
}
.flex_container_two .flex_two_one .flex_content{
    padding: 0 30px;
}
.flex_container_two .flex_two_three .flex_content{
     padding: 0 ;
     margin-top: 15px;
}
.brca-testing .brca_flex_three .test-patient-wrap .when-steps img {
    padding-right: 19px !important;
    padding-left: 20px !important;
}
}
@media only screen and (max-width:1002px) and (min-width:768px) {
/*US-63388 changes 25-06-22*/

.home_footnote .footnote-acronym {
    padding-left: 10px
}

.BRCA-Testing .home_footnote.acronym {
    padding: 0
}

.BRCA-Testing .home_footnote .footnote-acronym {
    padding-left: 20px
}
}
/*home page compatability*/
@media screen and (min-width: 900px) and (max-width: 1024px) { 

     .hcp-res.patient-res .card-img {
            width: 100px !important;
            height: auto !important;
        }
}
@media screen and (min-width: 767px) and (max-width: 1003px) { 
.polo.olaparib-safety-tolerability.safety-tolerability .home_footnote.container-center {
padding-left:20px;
}
}

@media screen and (min-width: 900px) and (max-width: 1003px) { 
.nccn_clinical, .olaprib_cat {
        padding-left: 15.8% !important;
    }
}
@media screen and (min-width: 992px) and (max-width: 992px) { 

   .resource-library.video-library .hcp-res .card-img {
    display: block;
}
 .resource-library .pancreatic-column-1 {
    height: 200px !important;
}
.resource-library .pancreatic-column:nth-child(1) {
    height: 160px !important;
}
}

@media screen and (min-width: 767px) and (max-width: 992px) {
.resource-library .pancreatic-column-1 {
    margin-left: 3px !important;
} 
.resource-library .pancreatic-column img.card-img-m.img-hcp-res1 {
    max-width: 200px !important;
}

.resource-library .pancreatic-column-1 img.card-img-m {
    max-width: 200px !important;
}

}

@media screen and (min-width: 901px) and (max-width: 992px) { 
.pancreatic-column, .pancreatic-column-1 {
min-height: unset !important;
    }
   .pancreatic-column, .pancreatic-column-1 {
        height: unset !important;
    }        


}

@media screen and (min-width: 767px) and (max-width: 900px) { 
.pancreatic-column, .pancreatic-column-1 {
         min-height: unset !important;
        }

}
 /*Video thumnail */                               
@media screen and (min-width: 376px) and (max-width: 767px) {
    .resource-library .grid .thumbnail .thumb.active img {
    height: 100% !important;
}
} 
 /* End Video thumnail */                                                
@media screen and (min-width: 767px) and (max-width: 821px) { 

    .blueboxright {
        padding-top: 4.5% !important;
        min-height: 111px;
    }
}
@media screen and (min-width: 822px) and (max-width: 841px) { 


    .blueboxright {
        padding-top: 2.8% !important;
        min-height: 88px;
    }
}
@media screen and (min-width: 700px) and (max-width: 766px) { 

.brca-testing .test-patient-wrap {
            width: 500px !important;
        }
        .brca-testing .when-steps {
            width: 345px;
            margin: 0 auto;
        }
}
@media screen and (min-width: 601px) and (max-width: 699px) { 
.brca-testing .test-patient-wrap {
            width: 345px !important;
        margin-left: -8% !important;
        }

}

@media only screen and (min-width: 377px) and (max-width: 767px) {
.olaparib-brca-testing .recommend_based {
    margin: 0px 0 10px !important;
    padding-left: 0% !important;
}

}

/*compatability test 2*/
@media only screen and (min-width: 800px) and (max-width: 1000px) { 
  .video-library .thumbnail .col-xs-12:nth-child(1) div.thumb img.philp-video {
    height: auto !important;
}
 }  
@media only screen and (min-width: 700px) and (max-width: 750px) { 
  .brca-testing .brca_flex_two .container-center .flex_content .test-patient-wrap {
        margin-left: -22% !important;
    }
 }
@media only screen and (min-width: 698px) and (max-width: 699px) { 
  .brca-testing .brca_flex_two .container-center .flex_content .test-patient-wrap {
        margin-left: -8% !important;
    }
 }
@media only screen and (min-width: 650px) and (max-width: 699px) { 
  .brca-testing .test-patient-wrap {
        margin-left: -8% !important;
    }
 } 

@media only screen and (min-width: 500px) and (max-width: 700px) { 
 .treatment_paradigm .nccn_guidelines {
       font-size:13px;
line-height:16px;
    } 

.polo #footer .home_footnote {
    font-size: 10px;
	line-height:13px;
}  
.polo .home_footnote {
    font-size: 14px;
	line-height:16px;
}                                                                                                
.polo .prognastic.lab .home_footnote {
    font-size: 14px !important;
	line-height:16px;
}
/*.treatment_paradigm .recommend .recommend_based {
        font-size: 16px !important;
        line-height: 20px;
    }
.treatment_paradigm .recommend ul.recommend_bullet li {
        font-size: 16px !important;
        line-height: 20px;
    }*/
.treatment_paradigm .home_footnote {
 font-size: 12px !important;
	line-height:16px;                                                                              
 }
 }                                                                          

  @media only screen and (min-width: 501px) and (max-width: 550px) { 
  .brca-testing .test-patient-wrap {
        margin-left: -20% !important;
    }
 } 
 @media only screen and (min-width: 697px) and (max-width: 698px) { 
  .brca-testing .test-patient-wrap {
        margin-left: 0% !important;
    }
 }
 @media only screen and (min-width: 400px) and (max-width: 569px) { 
.dosing .dose-img-text-container .dose-img {
    padding: 5px 0px 5px 10px;
}
 }

@media only screen and (min-width: 400px) and (max-width: 410px) { 
  /*.brca-testing .test-patient-wrap {
        margin-left: -42% !important;
    }*/
 } 
 @media only screen and (min-width: 411px) and (max-width: 430px) { 
  .brca-testing .test-patient-wrap {
        margin-left: -35% !important;
    }
 }   
 @media only screen and (min-width: 431px) and (max-width: 460px) { 
  .brca-testing .test-patient-wrap {
        margin-left: -30% !important;
    }
 } 
  @media only screen and (min-width: 461px) and (max-width: 500px) { 
  .brca-testing .test-patient-wrap {
        margin-left: -25% !important;
    }
 }  

  @media only screen and (min-width: 320px) and (max-width: 360px) {

.brca_content_bg .flex_content .flex_heading {
padding-left: 0% !important;
 }       
.brca-testing .mobile .brca_content_bg .flex_content {
 padding-left: 0% !important;                                                                                                                               
}
.brca-testing .mobile .flex_content {
        padding-left: 108px;
    }
	    .mobile .olaparib-brca-testing .flex_heading {
        padding-left: 0%;
    }
 } 

 @media only screen and (min-width: 320px) and (max-width: 369px) { 
.dosing .dose-img-text-container .dose-img {
    padding: 5px 0px 5px 10px;
}
 } 

  @media only screen and (min-width: 351px) and (max-width: 360px) {
.brca-testing .test-patient-wrap {
        margin-left: -41% !important;
    }
}    
 @media only screen and (min-width: 341px) and (max-width: 350px) {
.brca-testing .test-patient-wrap {
        margin-left: -45% !important;
    }
}
  @media only screen and (min-width: 331px) and (max-width: 340px) {
.brca-testing .test-patient-wrap {
        margin-left: -52% !important;
    }
}                                                                                                
  @media only screen and (min-width: 320px) and (max-width: 330px) {
.brca-testing .test-patient-wrap {
        margin-left: -58% !important;
    }
} 


/* End compatability test 2*/

@media only screen and (min-width: 320px) and (max-width: 350px) {
.dosing-page .rec-dosage-body {
            padding: 7% 2% !important;
        }
.treatment_paradigm .mobile .flex_two {
    height: unset;
}                                                                               
/*.dosing-page #maincontent p, .dosing-administration-oc #maincontent p, .dosing-administration-bc #maincontent p, .dosing-page #maincontent ul>li, .dosing-administration-oc #maincontent ul>li, .dosing-administration-bc #maincontent ul>li {
            font-size: 11.5px !important;
            line-height: 16px;
        }*/
#modal-content-wrapper .modal-dialog .modal-content {
            width: 315px;
            top: calc(40vh - 160px);
            left: calc(50vw - 158px);
        }                

}

/* end home page compatability*/
@media only screen and (max-width:767px) {
.brca-testing .test-patient-wrap{
    margin: 0 auto;
    width: 300px;
    text-align: center;
    margin-left: -41%;
}
.brca-testing .when-steps{
    display: flex;
    align-items: baseline;
}
.brca-testing .whenSteps p {
    margin-top: 20px;
    line-height: 16px;
    color: #000;
    font-size: 10px;
}
.test-patient-brca {
    margin-left: -41%;
    padding-left: 12px;
}
.brca-testing .when-steps img {
    max-width: 50px;
    max-height: 50px;
    padding: 0 5px;
}
.test-patient-wrap {
    background: none;
    margin: 0 0 50px 0;
    padding-top: 20px;
}

.test-patient-wrap {
    margin-bottom: 0;
    padding-bottom: 25px;
}

.brcanalysis-text {
    padding: 0;
    padding-right: 20px;
}

p.bold-text span.visible-xs {
    display: inline-block !IMPORTANT;
}

p.bold-text span.visible-xs img {
    max-width: 165px;
}

.brcanalysis-text p.bold-text {
    font-size: 16px;
}

.test-patient-brca.when-testing-img {
    width: 100%;
    min-width: 300px;
    padding-top: 20px;
    padding-left: 12px;
}
}
p.recommend_bullet.blackf {
color: #000;
padding-left: 80px;
}
.home_footnote.container-center.nccn {
visibility: hidden;
margin-top: -55px;
}
span.word-breaker {
word-break: break-all;
}
.when-testing-img {
width: 400px;
padding-top: 20px
}
@media only screen and (min-width:1024px) {
/*
.fullnavigation .navbar-default .navbar-nav>li.olaparib-dose-management {
right: 228px;
}
*/

#header .indication-selector .header-dropdown.isi-headerin {
    display: none;
    left: 488px;
    z-index: 0;
}

.efficacy .two .flex_two img,
.efficacy .two .flex_one img {
    width: 75%;
}

.efficacy .flex_container.two {
    text-align: center;
}

.efficacy .two .flex_one {
    margin-left: 10px;
}

.header-dropdown.isi-headerin a {
    width: 146px !important;
    background-color: #004d74;
    color: #ffffff;
    border-radius: 10px;
    padding: 4px 0;
    font-family: 'Roboto-Medium';
    font-size: 14px;
    border: solid 2px #ffffff;
    display: block !important;
    white-space: normal !important;
    line-height: 16px;
    height: 40px;
    padding: 3px 5px;
    text-align: center;
    max-width: 146px !important;
}

.fullnavigation .navbar-default .navbar-nav>li.olaparib-dose-management a,
.fullnavigation .navbar-default .navbar-nav>li.olaparib-patient-support a {
    /*width: 146px;*/
    background-color: #004d74;
    color: #ffffff;
    border-radius: 10px;
    /*padding: 4px 0;*/
    font-family: 'Roboto-Medium';
    font-size: 14px;
    border: solid 2px #ffffff;
    white-space: normal !IMPORTANT;
    /*line-height: 16px;*/
    height: 40px;
    /*padding: 2px;*/
}
/*
#header .indication-selector .header-dropdown ul{
width: 305px;
}
*/

#header .indication-selector .header-dropdown ul li .child-inner {
    padding-left: 15px;
}

.header-dropdown.isi-headerin a:hover {
    background-color: #f7941f;
    border-color: #f7941f;
    text-decoration: none;
}
/*
#header .search-box>.search form input#search {
width: 470px;
}
#header .search-box>.search form {
width: 525px;
}
*/
/*
.fullheader ul.list-inline li:nth-child(4) {
display: none;
}
*/
/*
.fullheader ul.list-inline {
display: flex;
justify-content: space-between;
}
.fullheader ul.list-inline li {
margin: 0;
}
*/

.progress_img.orr_flag {
    max-width: 940px;
}
}
span.postop {
position: relative;
top: -1px;
}
span.customBold.increase-pt {
font-family: 'Roboto-Bold';
font-size: 14px;
}
@media screen and (-ms-high-contrast: active),
(-ms-high-contrast: none) {
.treatment_paradigm .yellow_eyebrow p, .treatment_paradigm .yellow_eyebrow h1 {
    padding-right: 9%;
}

ul.recommend_bullet li:before {
    content: "\2022";
    font-size: 24px;
}

ul.recommend_bullet li {
    text-indent: 10px;
}
}

/***** Updated_1 *****/
.no-wrap {
white-space: nowrap;
}
.brca-testing .yellow_eyebrow .container-center em sup {
font-style: normal;
padding-left: 2px;
}
.brca-testing .brca_content_bg .flex_content .test-patient-brca {
flex-direction: column;
align-items: start;
padding: 0;
width: 100%;
}
.brca-testing .brca_content_bg .flex_content .test-patient-brca .brcanalysis-img {
margin-left: 0;
max-width: 560px;
width: 100%;
text-align: center;
}
.brca-testing .brca_content_bg .flex_content .test-patient-brca .brcanalysis-text {
padding-left: 2px;
}
.brca-testing .brca_content_bg .flex_content .test-patient-wrap {
margin: 28px 0 0px 2px;
padding: 0;
background-color: transparent;
width: 560px;
}
.flex_one,
.flex_two,
.flex_three {
flex: 1;
display: flex;
align-items: start;
}
.polo .flex_one,
.polo .flex_two,
.polo .flex_three {
flex: 1;
display: flex;
align-items: center;
justify-content: center;
}
.flex_container img {
margin-right: 0%;
}
.container-center.nw-img .progress_img {
position: relative;
right: 30px;
max-width: 85%;
}
.nw_column .col-6.col-md-4 {
max-width: 20%;
}
.nw_column .col-12.col-md-8 {
width: 80%;
}
.nw_column p.pan-col-text {
margin-top: -6px;
}
.sm_img img {
width: 200px;
max-width: 75%;
}
.brca-testing .brca_content_bg .flex_content .test-patient-brca .brcanalysis-img img {
padding: 0;
}
p.normalt.nw-p {
margin: 12px auto;
max-width: 560px;
text-align: center;
position: relative;
left: -20px;
margin-top: 0;
}
span.visible-xs.sm_img {
text-align: center;
}


@media only screen and (max-width: 1003px){
.container-center.footnote-content.ref-foot {
padding-left: 20px;
padding-right: 20px;
}
/* compatability*/
/*.polo.olaparib-safety-tolerability.safety-tolerability .container-center, .fullheader .logos .logo {
                padding-left: 20px !important;
 padding-right: 20px !important;
                    }*/

.dosing-page #maincontent {
    margin-top:92px !important;
}



.common-tagging {
            background: unset;
        }
  .nccn_guidelines {
            margin-top: 1.4%!important;
        }
        img.video-thumb.thumb0.philp-video-thumbnail {
            height: auto !important;
        }

/* end home page compatability*/
        .home_footnote .footnote-acronym {
  padding-left: 20px;
}

.safety-tolerability .home_footnote p {
  padding: 0;
}

}

@media only screen and (min-width: 768px) {

.flex_container_two{
margin-bottom: 20px;
}
.brca-testing .test-patient-wrap{
text-align: center;
}
.brca-testing .when-steps{
display: flex;
align-items: baseline;
}
.brca-testing .whenSteps p {
margin-top: 30px;
line-height: 16px;
color: #000000;
}
.brca-testing .test-patient-wrap .when-steps img{
padding-right: 24px !important;
padding-left: 24px !important;                        
}
.randomization-step img {
max-width: 130px;
}
/*.brouchure-desc p {
padding-left: 8px;
}*/
 .nccn_guidelines {
            margin-top: 1.4%;
        }
}
@media only screen and (max-width: 767px) {
 /*compatibility test */
/*.dosing-page #maincontent h1, .dosing-administration-oc #maincontent h1, .dosing-administration-bc #maincontent h1 {
 font-size: 16px !important;
  }
.polo.olaparib-safety-tolerability.safety-tolerability .container-center, .fullheader .logos .logo {
                padding-left: 10px !important;
 padding-right: 20px !important;
                    }*/
.treatment_paradigm .flex_two img {
            max-height: unset !important;
        }

/* end  compatibility test */
.flex_container_two p.flex_content{
padding: 0 !important;
}
.flex_container_two.container-center div {
margin-bottom: 48px;
margin-top: 0;
}
.flex_container_two .flex_two_two img,
.flex_container_two .flex_two_three img,
.flex_container_two .flex_two_one img{
margin-bottom: 24px;
}
.flex_container_two .flex_two_two img,        
.flex_container_two .flex_two_three img {
padding-top: 0;
}
.randomization-step img {
max-width: 250px;
}
.flex_two_three .flex_content {
margin-left: 0 !important;
padding: 0;
}
.olaparib-efficacy .container-center.nw-img .progress_img{
right: 0;
}
}  
.recommendPadLeft {
 padding-left:10% !important;

}
.pad0left{
padding-left:0% !important;
    padding-right: 10%;
}
.borderbox {
    border-style: solid;
    border-width: 1px;
    border-color: black;
}
.blueboxright{
	width: 128px;
    height: 88px;
    float: left;
    background: #004d74;
        padding-top: 2%;
    padding-left: 10px;
}
.whitextbox {
	color:white;
    font-family: 'Roboto-Regular';
    margin-top: 30px !important;
    font-style: italic;
}
.blacktpadtop {
color:black;
    padding-top:8px;
}
.home_footnote.container-center.indent.pad0left {
    text-indent: 0px;
}

.moa .yellow_eyebrow h1 {
    margin: 0;
    font-size: 30px;
    font-family: 'Roboto-Bold';
    line-height: 35px;
    color: #004D74;
}