/* Solo - 2 starts */

.oc-efficacy-solo2 #maincontent p.banner-subhead {
    font-size: 18px;
    line-height: 24px;
    color: white;
}

.oc-efficacy-solo2 #maincontent h1 {
    padding: 0 !important;
}
#maincontent .sticky-nav .dropdown-toggle#on-this-page {
    display: none;
}

#maincontent .sticky-nav {
    background-color: #004D74;
    border-top: 1px solid white;
    padding: 19px 0 8px;
}

#maincontent .npp-max-width {
    max-width: 1024px;
    margin: 0 auto;
}

#maincontent .sticky-nav .npp-max-width img {
    padding: 0 !important;
    margin: 0 !important;
    width: 28px;
}

#maincontent .sticky-nav .dropdown-toggle {
    display: flex;
    gap: 16px;
}


#maincontent .sticky-nav .dropdown-toggle .content p {
    margin: 0;
    color: white;
    font-size: 12px;
    line-height: 120%;
    text-transform: uppercase;
}

#maincontent .sticky-nav .dropdown-toggle .content p.sticky-head {
    font-size: 16px;
    text-transform: uppercase;
    font-family: 'Roboto-Bold';
}

#maincontent .sticky-nav ul.sticky-inpage-links {
    padding-top: 11px;
    color: white;
    display: flex;
    background-color: #004D74;
    border-radius: 0;
    position: static;
    min-width: unset;
    max-width: unset;
    width: 100% !important;
    margin: 0 !important;
    float: unset;
}

#maincontent .sticky-nav ul.sticky-inpage-links a {
    color: white;
    font-size: 14px;
    line-height: 24px;
    font-family: 'Roboto-Bold';
    padding: 0 !important;
    margin: 0;
    border-bottom: 5px solid transparent;
}

#maincontent .sticky-nav ul.sticky-inpage-links li {
    padding: 0 32px;
    border-right: 1px solid white;
}

#maincontent .sticky-nav ul.sticky-inpage-links li:first-child {
    padding-left: 0;
}

#maincontent .sticky-nav ul.sticky-inpage-links li:last-child {
    border: none;
}

#maincontent .sticky-nav ul.sticky-inpage-links a.section-active,
#maincontent .sticky-nav ul.sticky-inpage-links a:hover {
    border-bottom: 5px solid white;
}

.oc-efficacy-solo2 .esmo-sec-id, .dosing .esmo-sec-id{
    scroll-margin-top: 190px;
}

.oc-efficacy-solo2 #maincontent .section-eyebrow {
    color: #004D74;
    font-size: 25px;
    line-height: 120%;
    margin-bottom: 13px;
}

.oc-efficacy-solo2 #maincontent .section-eyebrow span {
    padding: 4px 10px 4px 8px;
    background-color: #56849F;
    color: white;
}

#maincontent .explore-next-section .flex-box .box p.card-title:has(span) span.solo-1 {
    background-color: #2076A5;
}

.eff-solo2 p.bannerftnote {
    margin-bottom: 13px;
}

.oc-efficacy-solo2 .bicr.bicr2 {
    margin-bottom: 40px;
}

.explore-next-section {
    background-color: #EAF2FA;
    padding: 30px 0;
}

#maincontent .explore-next-section .section-head p {
    font-size: 25px;
    line-height: 34px;
    color: #004D74;
    margin-bottom: 16px;
}

#maincontent .explore-next-section .flex-box .box {
    border: 1px solid #7F9C21;
    width: 100%;
    display: flex;
    gap: 16px;
    padding: 16px;
    background-color: white;
}

#maincontent .explore-next-section .flex-box {
    display: flex;
    justify-content: space-between;
    gap: 32px;
}

#maincontent .explore-next-section .flex-box .box p.card-title {
    font-size: 24px;
    line-height: 100% !important;
    font-family: 'Roboto-Bold';
    color: #004D74;
    margin-bottom: 3px;
}

#maincontent .explore-next-section .flex-box .box p.card-title:has(span) {
    font-size: 25px;
    line-height: 120%;
    margin-bottom: 8px;
}

#maincontent .explore-next-section .flex-box .box p.card-title:has(span) span {
    background-color: #60829D;
    color: white;
    padding: 7px 8px;
    display: inline-block;
}

#maincontent .explore-next-section .flex-box .box img {
    padding: 0;
    width: auto;
}

#maincontent .explore-next-section .flex-box .box .card-img {
    max-width: 77px;
    width: 100%;
    text-align: center;
    padding-left: 8px;
}

#maincontent .explore-next-section .flex-box .box a.card-link {
    display: inline-block;
    border: 1px solid #7F9C21;
    padding: 8px 27px 8px 16px;
    border-radius: 8px;
    color: #7F9C21;
    text-decoration: underline;
    font-family: 'Roboto-Bold';
    position: relative;
    font-style: italic;
}

#maincontent .explore-next-section .flex-box .box a.card-link:after {
    content: "";
    position: absolute;
    width: 6px;
    height: 12px;
    background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-oc/oc-npp-opt/desktop/dropdown-green-arrow.svg);
    background-size: cover;
    right: 16px;
    top: 50%;
    transform: translateY(-50%);
}

#maincontent .explore-next-section .flex-box .box p.card-data {
    font-size: 16px;
    line-height: 120%;
    margin-bottom: 16px;
}

#maincontent .explore-next-section .flex-box .box a.card-link:hover {
    text-decoration: none;
}

/* Solo - 2 ends */
#maincontent .explore-next-section .flex-box .box p.card-title:has(span) span.dark {
    background-color: #004D74;
}

#maincontent .explore-next-section .flex-box .box a.card-link.external-link::after {
    background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-oc/oc-npp-opt/desktop/linkout-icon.svg);
    width: 16px;
    height: 16px;
}

#maincontent .explore-next-section .flex-box .box a.card-link.external-link {
    padding-right: 37px;
}

/* Dosing starts */

#maincontent .section-head-tag {
    margin-bottom: 20px;
}

.dosing-page #maincontent .section-head-tag p.section-eyebrow {
    margin: 0;
    font-size: 25px;
    line-height: 120%;
    color: white;
    font-family: 'Roboto-Bold';
    border-bottom: 2px solid #2076A5;
}

.dosing-page #maincontent .section-head-tag p.section-eyebrow span {
    background-color: #2076A5;
    display: inline-block;
    padding: 4px 10px;
    font-style: italic;
    margin-right: 12px;
}

.dosing-page #maincontent .section-head-tag p.section-eyebrow span.solo-2 {
    background-color: #56849F;
}

.dosing-page #maincontent .section-head-tag p.section-eyebrow span.paola-1 {
    background-color: #004D74;
}

.dosing-page #maincontent #combination-therapy .section-head-tag {
    margin-top: 70px;
    margin-bottom: 8px;
}

.dosing-page #maincontent #combination-therapy .section-banner-content p {
    color: #004D74;
    font-family: 'Roboto-Bold';
    margin-bottom: 0;
    font-size: 25px;
    line-height: 120%;
}

.dosing-page #maincontent #combination-therapy .section-banner-content p:first-child {
    margin-bottom: 8px;
    font-size: 19px;
}

.dosing-page #maincontent #combination-therapy .section-banner-content p .green-color {
    color: #7F9C21 !important;
}

.dosing-page #maincontent #combination-therapy .section-banner-content {
    margin-bottom: 70px;
}

.dosing-comb-esmo2 .yellow-container {
    margin-top: 0;
}

.dosing span.ss-notskew {
    transform: skewX(10deg);
    display: inline-block;
}

.dosing-page thead {
    border: 1px solid #000000;
}

.dosing-page .dosing-new-table td,
.dosing-new-table th {
    border: 1px solid black;
}

.dosing-page .dosing-new-table.dosing-c-tab table thead tr:last-child {
    border: none;
}

.dosing-page .dosing-new-table thead tr:first-child th {
    font-size: 16px;
    font-family: 'Roboto-Bold';
    background-color: #E6EFF5;
}

.dosing-page .dosing-new-table thead tr:nth-child(2) th {
    font-size: 15px;
}

.dosing-page .dosing-new-table.dosing-c-tab tbody td {
    font-size: 15px;
    padding-left: 8px;
    font-weight: 600;
    line-height: 120%;
    padding: 11px !important;
}

.dosing-page .new-median p.bold-blackhead {
    margin-bottom: 0 !important;
}

.dosing-page .orange-content {
    margin: 33px auto 40px;
}

.dosing-comb-esmo2 .dosing-new-table.dosing-c-tab+ul.blue-list {
    padding-left: 25px;
}

.dosing-page  .rec-dosage-body img.desktop {
    max-width: 445px;
    padding-bottom: 0;
}
.dosing  .dose-img-text-container .dose-img {
    max-width: 70px;
    width: 100%;
    padding: 0;
    margin-right: 16px;
}

.dosing-comb-esmo2.dosing  .dosing-callouts .dose-img-text-container img {
    padding-bottom: 4px;
}
/* Dosing ends */
/**Staging 1 feedback**/
.select-from-text {
    background: #004D74;
    border-top: 1px solid white;
    padding: 19px 0 17px;
}
.select-from-text > div {
    max-width: 1024px;
    margin: 0 auto;
    display: flex;
    gap: 16px;
    justify-content: flex-start; 
}
#maincontent .select-from-text img {
    margin: 0 !important;
    padding: 0 !important;
    width: 28px;
}
#maincontent .select-from-text p {
    margin: 0;
    color: white !important;
    font-size: 16px  !important;
    text-transform: uppercase;
    font-family: 'Roboto-Bold' !important;
}
#maincontent .select-from-text .content p.sticky-desc {
    font-size: 12px !important;
    line-height: 120%;
    font-family: 'Roboto-Regular' !important;
}
body:has(.select-from-text) #maincontent .sticky-nav {
    padding-top: 0;
    border-top: 0;
}
body:has(.select-from-text) #maincontent .sticky-nav div#on-this-page {
    display: none;
}
.hrd-testing .common-headline h1.esmo-h1 {
    font-size: 30px !important;
    line-height: 36px !important;
}
.rich-text:has(.in-page-sec-menus) {
    /*top: 75px;*/
}
@media screen and (min-width:1004px){
    #dosing  .dosing-callouts {
    	padding-bottom: 129px;
	}
    .dosing-comb-esmo2 #maincontent .container-center.inner-wrapper .neww-table+h2,.dosing-comb-esmo2 #maincontent .container-center.inner-wrapper .neww-table+h2+h2 {
    	font-size: 19px !important;
    	line-height: 120% !important;
    	margin-bottom: 8px !important;
	}
	.eff-solo2 .common-headline .container-center {
    	max-width: 1027px;
	}
	.dosing  .dose-img-text-container {
    	align-items: center;
	}
	.dosing-administration-oc.dosing.combination-therapy .common-headline {
    	padding: 32px 0 !important;
	}
}

@media screen and (max-width:1003px) {
    #maincontent .npp-max-width {
        padding: 0 16px;
    }

    #maincontent .sticky-nav ul.sticky-inpage-links {
        padding-top: 31px;
        padding-left: 42px;
    }

    #maincontent .sticky-nav ul.sticky-inpage-links li {
        padding: 0 0 16px 20px !important;
        border: none;
        border-left: 1px solid white !important;
    }

    #maincontent .sticky-nav ul.sticky-inpage-links li a.section-active {
        background-image: none;
        /* border: none; */
    }

    #maincontent .sticky-nav ul.sticky-inpage-links li a {
        background: transparent;
        border: none;
        display: inline;
    }

    #maincontent .sticky-nav ul.sticky-inpage-links li:last-child {
        padding-bottom: 0 !important;
    }

    .oc-efficacy-solo2 .esmo-sec-id,.dosing .esmo-sec-id {
        scroll-margin-top: 170px;
    }

    .eff-solo2 p.bannerftnote {
        margin-bottom: 24px;
    }

    .oc-efficacy-solo2 #maincontent .section-eyebrow {
        margin-bottom: 24px;
    }

    #maincontent .sticky-nav .npp-max-width {
        padding: 16px;
    }

    .explore-next-section {
        padding: 20px 0;
    }

    #maincontent .explore-next-section .flex-box {
        flex-direction: column;
    }

    #maincontent .section-head-tag {
        margin-top: 28px;
    }

    .dosing-callouts .container-center.inner-wrapper,
    .dosage.doubled-ORR .container-center.inner-wrapper,
    .dosage.doubled-ORR+.container-center.new-median {
        padding: 0 20px;
    }

    .dosing-page #maincontent #combination-therapy .section-banner-content {
        margin-bottom: 30px;
    }

    .dosing-page #maincontent #combination-therapy .section-head-tag {
        margin-top: 50px;
    }

    .dosing-page #maincontent #combination-therapy .section-banner-content p:last-child {
        font-size: 33px;
    }

    .dosing-page .dosing-new-table thead tr:nth-child(2) th {
        font-weight: 700;
    }

    .dosecallout .callout .text {
        max-width: 100% !important;
    }

    .dosing-comb-esmo2 .dosecallout .callout .image.mob-mg-0 img {
        margin: 0;
        max-width: 180px;
        width: 100%;
    }

    .combination-therapy.dosing-administration-oc .grid.section .dosingcallout .col-xs-12.col-sm-4:last-child {
        margin-bottom: 16px;
    }

    .dosing-comb-esmo2 .dosecallout .callout .image.mob-mg-0 {
        max-width: 100%;
        width: 100%;
    }
	.combination-therapy.dosing-administration-oc .grid.section .dosingcallout .col-xs-12.col-sm-4:nth-child(2) .image.mob-mg-0 img {
    	max-width: 80px;
	}
    /**staging 1 feedback**/
    .rich-text:has(.in-page-sec-menus) {
        top: auto;
    }
    .select-from-text > div {
        padding: 16px 16px 0;
    }
    body:has(.select-from-text) #maincontent .sticky-nav .npp-max-width {
        padding-top: 0;
    }
    .select-from-text {
        padding-bottom: 0;
    }
    .dosing-page.monotherapy.esmo-body main#maincontent, .combi.esmo-body main#maincontent {
        margin-top: 159px !important;
    }
	.dosing-comb-esmo2 #maincontent .dosing-callouts .container-center.inner-wrapper h2,
    .dosing-comb-esmo2 #maincontent .container-center.inner-wrapper h2.bluehead,
.dosing-comb-esmo2 #maincontent #monotherapy .new-median.container-center .median-common-ar h2.bluehead:first-child {
    	font-size: 19px !important;
    	line-height: 23px !important;
	}
    .dosing-comb-esmo2 #maincontent .container-center.inner-wrapper h2.subchart-head {
    	font-size: 16px !important;
    	line-height: 19px !important;
	}
    .dosing-page .new-median p.bold-blackhead:last-child {
    	margin-bottom: 40px !important;
	}
    .safety-p1 .content-inner-wrapper h2 {
        font-size: 25px !important;
        line-height: 32px !important;
    }
    .dosing-comb-esmo2 .big-note.bulleted.sub-list:before {
        padding-left: 2px;
    }
    .dosecallout.flex_two_two .callout {
    	display: flex;
	}
	.dosecallout.flex_two_two .callout .image {
    	max-width: 80px !important;
    	margin-top: -60px;
	}
	.dosecallout.flex_two_two .callout .text .callout-text {
    	font-size: 14px !important;
	}
	.oc-efficacy-solo2 #maincontent img.mtop-16 {
    	margin-top: 16px;
	}
	.oc-safety-tolerability-solo2 .footer-parsys>.text>.container-center:has(.esmo-abbv-section) {
    	padding: 0 20px;
	}
	.dosing-administration-oc .modifications .row-head {
    	min-width: 42px;
	}
}

@media (min-width:320px) and (max-width: 327px) {

 .npp-solo-update.oc-npp-opt-solo2.oc-efficacy-solo2 .common-headline{
            padding-top: 40px !important;
}


}


@media (min-width:1004px) and (max-width: 1030px) {

.oc-npp-opt-solo2 .explore-next-section {
    
    padding: 30px 20px!important;
}

}

@media (min-width:1004px) and (max-width: 1105px) {
.hrd-com .explore-next-section {
    padding: 30px!important;
                            }
        .oc-safety-tolerability-solo2 .explore-next-section {

    padding: 30px 20px !important;
        }

}




@media (min-width:1004px) and (max-width: 1030px) {

.hrd-com .esmo-max-width {

    padding: 0 18px!important;
                            }
                            }

        @media (min-width:1023px) and (max-width: 1035px) {
       .oc-safety-tolerability-solo2 .study-design ul.body-foot {
    padding-left: 10px !important;
}





    }
            @media (min-width:1023px) and (max-width: 1040px) {
            .oc-safety-tolerability-solo2 .neww-table {

    padding: 0 10px;
}
                   .oc-safety-tolerability-solo2 .study-design h2.bluehead {
    padding-left: 10px;
}
                         .oc-safety-tolerability-solo2 .study-design p.bold-blackhead {
    padding-left: 10px;
}
                                    .oc-safety-tolerability-solo2 .study-design ul.body-foot {
        padding-left: 16px !important;
                                            }


        }
@media (min-width:1004px) and (max-width: 1070px) {

.oc-safety-tolerability-solo1 .explore-next-section {

    padding: 30px 20px;
}

}

@media (min-width:1023px) and (max-width: 1040px) {
        .container-center, .isi {
        padding-left: 20px!important;
        padding-right: 20px!important;
    }
}

@media screen and (min-width:1004px) and (max-width:1300px){
	.in-page-header .in-page-menus ul li.has-subpage:last-child:has(a:hover) ul li a {
    	padding: 8px;
	}
	.in-page-menus>div {
    	max-width: 1096px;
	}
}

@media (min-width:1004px) and (max-width: 1075px) {
.dosing-comb-esmo2 #maincontent .container-center.inner-wrapper {
        padding-left: 30px !important;
        padding-right: 30px !important;
    }
.dosing-comb-esmo2 .section-head-tag p.section-eyebrow {

    margin-left: 30px!important;
    margin-right: 30px!important;
}
.dosing-comb-esmo2 #maincontent #combination-therapy .section-banner-content {

    margin: 0 30px!important;
}
.dosing-comb-esmo2 .explore-next-section {

    padding: 30px!important;
}
.dosing-comb-esmo2 .esmo-max-width {

    margin: 0 30px!important;
}


}
 @media (min-width:320px) and (max-width: 345px) {
 .dosing-page .dosing-new-table.dosing-c-tab tbody td {

    padding: 0px 2px !important;


                    }
                                    .dosing-page .dosing-new-table thead tr:nth-child(2) th {
    font-size: 14px!important;
}
                                }

                        @media (min-width:1004px) and (max-width: 1055px) {
                        .dosing-page .select-from-text {
    background: #004D74;
    border-top: 1px solid white;
    padding: 19px 0 17px;
    padding-left: 25px;
                    }
        .dosing-page #maincontent .sticky-nav ul.sticky-inpage-links {
        padding-left: 25px;}}

@media only screen and (min-width: 1004px) and (max-width: 1055px) {
   .oc-safety-tolerability-solo2 #maincontent .common-headline {
        padding: 50px 20px !important;
    }
}
    @media only screen and (min-width: 500px) and (max-width: 1003px) {
        .combination-therapy .dosecallout.flex_two_three .callout.callout2 .image img {

         margin-left: 0px!important;
    }
        }


    @media only screen and (min-width: 378px) and (max-width: 768px) {
    .combination-therapy.dosing-administration-oc .grid.section .dosingcallout .col-xs-12.col-sm-4:nth-child(2) .image.mob-mg-0 img {

        margin-left: 14px!important;
    }
}
  @media only screen and (min-width: 530px) and (max-width: 1003px) {
    .combination-therapy.dosing-administration-oc .grid.section .dosingcallout .col-xs-12.col-sm-4:nth-child(2) .image.mob-mg-0 img {

        margin-top: 20px!important;
                 margin-left: 2px!important;                                                                                  }} 

  @media only screen and (min-width: 1004px) and (max-width: 1020px) {
.oc-safety-tolerability-solo1 .isi-tray .isi-tray-head .tray-opener {

        margin-right: 25px!important;
                                                                                                        }}
 @media only screen and (min-width: 1024px) and (max-width: 1041px) {
   .dosecallout .callout .text {

        margin-right: 8px!important;

                                                                                                                    }}

   @media only screen and (min-width: 1004px) and (max-width: 1023px){
  .dosing-comb-esmo2 .rec-dosage {
         flex-direction: row!important; 
                                                                                                           }
     .mono .recommended-dosage.rec-dosage {

        margin-bottom: 0px !important;
    }
     .monotherapy .dose-reduction, .monotherapy .dose-interruption {
        margin-top: 10px;
    }
                                                                                                                            }

@media only screen and (min-width: 320px) and (max-width: 360px) {
    .combination-therapy .dosecallout.flex_two_three .callout.callout2 .image img {

 margin-left: 0px!important; }


.combination-therapy .callout-heading {

    margin-right: 20px!important;
                                                                                                                     }}



  @media only screen and (min-width: 768px) and (max-width: 1003px) {
    .combination-therapy.dosing-administration-oc .grid.section .dosingcallout .col-xs-12.col-sm-4:nth-child(2) .image.mob-mg-0 img {

              margin-left: 12px !important;
    }
}



  @media (min-width:991px) and (max-width: 1003px) {
    .hrd-testing .hrd-test-sec .what-box {

  flex-direction: column!important;}
                                                                                                                                       }

    @media (min-width:361px) and (max-width: 1003px) {
  br.sp-content {
    display: none;
}                                                                                                                                              }

    @media (min-width:1003px) and (max-width: 2560px) {
  br.sp-content {
    display: none;
}                                                                                                                                              }

 @media (min-width:320px) and (max-width: 361px) {
     .oc-safety-tolerability-solo2 .neww-table .reaction-name {
        font-size: 14px !important;                                                                                                                                             
                            }}


 @media (min-width:320px) and (max-width: 335px) {
     .dosing-page .dosing-new-table.dosing-c-tab tbody td {
    font-size: 13px!important;                                                                                                                                            
                            }}

 @media (min-width:1004px) and (max-width: 1023px) {
   .oc-efficacy-solo2 .container-center.content-inner-wrapper img.desktop {
    display: block !important;
}  
 .oc-efficacy-solo2 .container-center.content-inner-wrapper img.mobile {
    display: none !important;
}


                            }

 @media (min-width:1023px) and (max-width: 1040px) {
     .oc-safety-tolerability-solo1 .year-ans.desktop.container-center {
    padding-left: 50px !important;
    padding-right: 50px !important;

                            }}


 @media (min-width:1023px) and (max-width: 1024px) {
   .monotherapy #maincontent p.tablets-size {

    top: 4% !important;

                            }}

 @media (min-width:767px) and (max-width: 1003px) {

.oc-efficacy-solo2 .bicr2 .median-pf-container .median-pfs > div {
  display: block!important;
  transform: none !important;
}
.oc-efficacy-solo2 .bicr2 .median-pf-container .median-pfs p {
  transform: none !important;
}
.oc-efficacy-solo2 .bicr2 .median-pf-container .median-pfs>div {
  max-width: 335px !important;
}
.oc-efficacy-solo2 .bicr2 .median-pf-container .median-pfs > div {
  margin-top: 0px !important;
}
.oc-efficacy-solo2 .bicr2 .median-pf-container {
  display: flex!important;
  justify-content: center !important;
}
 .oc-efficacy-solo2 .bicr2 .median-pfs {

        margin: 0 auto!important;
                                     }
    .oc-efficacy-solo2 .bicr2 .median-pf-container .median-pfs>div:first-child {

        margin-left: 0% !important;
                                                                                            }}


 @media (min-width:1004px) and (max-width: 1021px) {
   .isi-tray .isi-tray-head .tray-opener {

        margin-right: 20px!important;
    }

                            }


@media only screen and (min-width: 1004px) and (max-width: 1022px) {
   .oc-efficacy-solo2 #maincontent .common-headline {
        padding: 50px 20px !important;
    }
.oc-npp-opt-solo2 .select-from-text {
        padding-left: 20px!important;
    }
   .oc-npp-opt-solo2 #maincontent .sticky-nav ul.sticky-inpage-links {
        padding-left: 20px!important;
    }                                                                                             
}

@media (min-width:1023px) and (max-width: 1040px) {
.oc-npp-opt-solo2 .select-from-text {
   
    padding-left: 20px!important;
}
.oc-npp-opt-solo2 #maincontent .sticky-nav ul.sticky-inpage-links {
  
    padding-left: 20px!important;
}
 .oc-npp-opt-solo2  #maincontent .common-headline {
        padding: 50px 0px !important;
    }  
                                                                                        }

 @media (min-width:1004px){ 


#combination-therapy .heading-custom-top{
  font-size: 28px !important;
    line-height: 33px !important;
    font-family: Roboto-bold;
    color: #004D74;
    border-bottom: none !important;
    padding-left: 0 !important;
    padding-bottom: 70px!important;}

  .dosing-page #maincontent #combination-therapy .section-head-tag {
    margin-top: 40px;
    margin-bottom: 8px;
}                                                                                              }


 .dosing-callouts .heading-custom-top {
   font-size: 28px !important;
    line-height: 33px !important;
    font-family: Roboto-bold;
    color: #004D74;
    border-bottom: none !important;
    padding-left: 0 !important;
    padding-bottom: 30px;
    padding-top: 20px;
}


  @media (max-width:1003px){ 
.dosing-callouts .heading-custom-top {  

padding-top:28px;
padding-bottom:30px;                                                                                }

     .rec-dosage {

        margin-top: 0px!important;
    }

  #combination-therapy .heading-custom-top{
  font-size: 25px !important;
    line-height: 33px !important;
    font-family: Roboto-bold;
    color: #004D74;
    border-bottom: none !important;
    padding-left: 0 !important;
    padding-bottom: 30px!important;
     padding-top:20px     }                                                                          

    .dosing-page #maincontent #combination-therapy .section-head-tag {
        margin-top: 0px!important;
                                                                            }}


@media screen and (min-width: 1004px) {
    #dosing .dosing-callouts {
        padding-bottom: 40px!important;
    }
}

@media (min-width: 1004px) {
    .dosing-page #maincontent #combination-therapy .section-head-tag {
        margin-top: 80px!important;

    }
}

@media (max-width: 1003px) {
    #combination-therapy .heading-custom-top {
           padding-top: 40px!important;
                                                                    }}


   .in-page-header .in-page-menus ul.oc-dropdown li.has-subpage:has(a:hover):last-child ul a {
    min-width: 188px;
    font-family: 'Roboto-Regular';
}

@media only screen and (min-width: 764px) and (max-width: 768px) {
    .combination-therapy.dosing-administration-oc .grid.section .dosingcallout .col-xs-12.col-sm-4:nth-child(2) .image.mob-mg-0 img {
        margin-left: 4px !important;
    }
}



#maincontent .explore-next-section .flex-box .box a.card-link:after {

    width: 8px!important;

}

@media only screen and (min-width: 768px) and (max-width: 1003px) {
        .combination-therapy.dosing-administration-oc .grid.section .dosingcallout .col-xs-12.col-sm-4 {

        width: 100%!important;
    }
}

@supports (-webkit-touch-callout: none) {
 
  @media only screen and (min-width: 820px) and (max-width:1106px) {

.in-pages-menus > div {
                                                                                                                                    max-width:1096px;
                                                                                                                                }
                                                                                                                                        .main-navigation .dropdown.select-tumor-dropdown > a {

                                                                                                                                                         background: url(../../../../../../content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-header-redesign/white-down-arrow.svg) no-repeat center right 7px!important;
                                                                                                                            }

 
  }

}


#maincontent .explore-next-section .flex-box .box a.card-link.cust-vtml::after {

                                                                                                                        width: 16px!important;}