/**/
/* Temp fix*/
/*.isi-tray{ display: none !important;}
/* Temp fix ends */
.paola-1.paola-veeva.eff-paola1.paola1-asco .references {
    letter-spacing: -0.03px;
}

span.space{
	padding-left:2px;
}
span.escapeItalic {
    font-style: normal;
}
	.patient-baseline .hrdPositiveChartLhs .eyebrow1{
                font-size: 14px;
    			margin-bottom: -15px;
     }
.induction{
        width:100%;
    }
sup.nineda {
    position: relative;
    left: 2px;
    font-style:normal;
}
span.ashh {
    position: relative;
    top: -2px;
}
sup.topr {
    position: relative;
    top: -11px;
}
.paolacontent-cell li,
.key-criteria li,
.paola-1 p,
.hrd-testing p {
	font-size: 16px;
	line-height: 20px;
}
.footer p{font-size: 14px;}
.hrd-testing .bold{font-family: 'Roboto-Bold';}
.daignosis-block{
	background-color: #EAF2FA;
}
.HRD-Testingv2 .common-headline h4{
    margin-top: 0px;
}
.hrd-testing .block-three h3{
    margin-top: 0px;
}
.hrd-testing .callout-block {
    margin-top: 30px;
}
.HRD-Testingv2 .callout-block {
    margin-bottom: 30px;
}
.patient-baseline .calloutDemographics p {
    color: #004D74;
    font-family: 'Roboto-Bold';
    font-size: 18px;
    line-height: 22px;
}
.hrd-testing .content-inner-wrapper{
    padding-top: 30px;
    }
.nccn_clinical {
    font-size: 18px;
    font-family: 'Roboto-Bold';
    padding-left: 15%;

}
.olaprib_cat {
    font-family: 'Roboto-Regular';
    font-size: 16px;
    padding-left: 15%;
}
.hrd-testing h3 {
	font-size: 20px;
	line-height: 25px;
	font-family: 'Roboto-bold';
	color: #004D74;
	border-bottom: 3px solid #004D74;
	/*padding-bottom: 15px;*/
	padding: 0px 0 8px 40px;
}
.pink-vars {
	color: #ff00c6 !important;
}
.pink-vars::before {
	content: "[" !important;
}
.pink-vars::after {
	content: "]" !important;
}
.hrd-testing .common-headline h3 {
    font-size: 20px;
    line-height: 25px;
    margin-bottom: 7px;
    font-style: italic;
    color: #ffffff;
            padding: 0;
}
.paola-1 .orange-color,
.hrd-testing .orange-color {
	color: #F7931D;
}
.normal{
    font-family: "Roboto-Regular";
    }
.block-one,
.block-two,
.block-three {
	margin-left: 4%;
}
.semi-colon{
	padding-left:2px;
    }

.block-one span.note img {
	margin-top: 40px;
	margin-bottom: 40px;
	margin-left: -10px;
}
.block-one p.block-one-text {
	font-size: 18px;
	line-height: 20px;
	font-family: Roboto-Bold;
}
.block-one p.block-one-text .normal-style {
	font-style: normal;
}
.block-one .image-scroll.mobile {
	margin-top: 30px;
}
.block-one .image-scroll.mobile img {
	height: 400px;
}

.common-headline h4 .pink-vars {
	color: #ff00c6 !important;
}
.common-headline h4 .pink-vars:before {
	content: "[";
}
.common-headline h4 .pink-vars:after {
	content: "]";
}
.footnote.extra-space {
	margin-top: 20px;
}


img.mark-img {
	position: absolute;
	margin: -40px;
}

.block-one p,
.block-two p {
	padding: 0px 0 0px 40px;
	margin: 33px 0px 45px 0px;
}

.block-three .three {
	margin: 38px 0px 0px 0px;
}
.block-three .tissue-order .list-capsule{
    margin-left: -22px;
}
.block-three .tissue-order .list-capsule a:active {
	color:#2a6496;
    text-decoration:underline;
}
/*.footnote {
	margin: 0px 0px 0px 24px;
}*/
.callout-block p {
    line-height: 26px;
	margin-bottom: 0;
	transform: skewX(10deg);
    font-size: 22px;
}

.callout-block {
	background-color: #ffe6cb;
	max-width: 70%;
	margin: 20px 0;
	text-align: left;
	color: #004D74;
	font-family: 'Roboto-Bold';
	font-style: italic;
	padding: 15px 30px;
	transform: skewX(-10deg);
	border-left: solid 9px #f7931d;
}

.tissue-order {
	margin-left: 2%;
    font-family: Roboto-Bold;
    font-size:16px;
}
.daignosis-block .tissue-order{
    padding-bottom: 5px;
}
.daignosis-block .block-three .tissue-order{

margin: 20px 0 0 40px;
}
.green-color {
	color: #B2D234;
}

.paola-1 .blue-color, .blue{
	color: #004D74;

}
.recommend_content {
    margin: 20px 0 0px 50px;
}

/*------------START OF EFFICACYPAOLA-1-----------------*/
/*.hrd-testing .pink-var, .paola-1 .pink-var{
	color: #ff00c6 !important;
}*/
.paola-1 .pink-var:before{
	content: "[";
}
.paola-1 .pink-var:after{
	content: "]";
}
.paola-1 .ftnote1.footnote{margin-left:0;}
.paola-1 ul.endpoint-list li{list-style:none;}
.paola-1 li.horline:last-child {
	border: none;
	margin-bottom: 0;
}

.paola-1 ul.list-view {
	margin-top: 35px;
	padding-left: 0px;
}

.paola-1 .sub-head p {
	font-size: 18px;
	text-align: center;
	font-family: 'Roboto-Bold';
	font-style: italic;
	line-height: 22px;
}
.paola-1 .references {
    margin-bottom: 45px;
}
.paola-1 ul.sub-list {
	padding: 0 0 0 20px;
	margin-top: 15px;
}

.paola-1 li.horline {
	font-family: 'Roboto-Bold';
}

.paola-1 ul.sub-list li, .paola-1 ul.sub-list p {
	font-family: 'Roboto-Regular';
}

.paola-1 ul.sub-list p {
	margin:0;
}

.paola-1 .sub-head p span.myriad-choice {
        background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-oc/desktop/my-choice-cdx-logo.png);
        width: 181px;
        height: 40px;
        display: inline-block;
        vertical-align: middle;
        background-size: 90%;
        background-repeat: no-repeat;
        background-position: -7px 0;
        mix-blend-mode: multiply;
    }    

.paola-1 .list-view li {
	list-style: none;
}

.paola-1 li.horline {
	margin: 20px 0px;
	padding: 0 0 15px 30px;
	border-bottom: 2px solid #333;
}

.paola-1 ul.endpoint-list li::before {
	content: ".";
	color: #333333;
	font-weight: bold;
	display: inline-block;
	width: 12px;
	margin-left: -13px;
	font-size: 30px;
	position: absolute;
	margin-top: -9px;
}
.paola-1 ul.sub-list li::before {
	content: ".";
	color: #333333;
	font-weight: bold;
	display: inline-block;
	width: 12px;
	margin-left: -19px;
	font-size: 30px;
	position: absolute;
	margin-top: -9px;
}


.paola-1 .list-view li::before {
	content: "\2500";
	color: #333333;
	font-weight: bold;
	display: inline-block;
	width: 16px;
	margin-left: -20px;
	font-size: 13px;
	position: absolute;
}

.paola-1 .paola-enrolled {
	position: relative;
}

.paola-1 .hrd-positive {
	background-color: #e5edf0;
}

.paola-1 .key-criteria {
	margin-left: 0%;
}

.paola-1 .patient-enrolled {
    font-family: 'Roboto-Bold';
    font-size: 17px;
    margin: 5px 0 25px 0;
    color: #004D74;
}
.paola-1 .key {
	font-size: 16px;
	font-family: 'Roboto-Bold';
	color: #004D74;
	border-bottom: 3px solid #004D74;
	padding: 0px 0px 12px 58px;
}

.paola-1 .paola-enrolled .circle {
	background-color: #B2D234;
	width: 51px;
	height: 51px;
	border-radius: 30px;
	position: absolute;
	margin-left: -2px;
}

.paola-1 .hrd-positive h2,
.paola-1 .patient-baseline h2,
.paola-1 .paola-study h2,
.paola-1 .paola-enrolled h2 {
	font-family: 'Roboto-Bold';
	line-height: 22px;
	font-size: 18px;
	color: #004D74;
	margin-top: 0;
}

.paola-1 .ftnote1.footnote p {
	font-size: 10px;
	line-height: 12px;
	font-family: 'Roboto-Light';
	color: #000000;
	margin-bottom: 0;
}

.paola-1 .indent-1 {
	text-indent: -5px;
	display: inline-block;
	width: 0!important;
}

.paola-1 .ftnote1.footnote {
	margin-top: 45px;
}

.paola-1 .patient-baseline .ftnote1.footnote {
	margin-top: 20px;
}

.paola-1 .patient-baseline {
	background-color: #e5edf0;
}
.paola-1 .paola-graph-func{
	background-color: #e5edf0;
}
.paola-1 p.ecog-per {
	margin-top: 25px;
}

.paola-1 .heading {
	margin-bottom: 25px;
}

.paola-1 p.cell-head {
	font-family: 'Roboto-Bold';
}

.paola-1 .paolacontent-cell {
	/*padding-top: 44px;*/
}
.paola-1 .paolacontent-cell p {
	margin-bottom: 4px;
}
.paola-1 .paolacontent-cell p,
.paola-1 .paolacontent-cell ul li {
	font-size: 14px;
	color: #3F4444;
	line-height: 17px;
}
.paola-1 .paolacontent-cell .paolacontent-cell-1 {
	/*border-top: 2px solid #B2D234;
	border-bottom: 2px solid #B2D234;*/
	padding: 0 10px;
}

.paola-1 .paolacontent-cell .paolacontent-cell-2 {
	margin-top: 22px;
	border: 2px solid #B2D234;
	padding: 15px;
}
.paola-1 .paolacontent-cell .paolacontent-cell-2 .cell-head {
	margin-bottom: 5px;
}
.paola-1 .paolacontent-cell .cell-head {
	color: #004D74;
}

.paola-1 .paolacontent-cell .pink-var {
	color: #FF00FF;
}

p.cell-head.secondary.blue-color {
	padding-top: 10px;
}

.paola-1 .paolacontent-cell ul {
	padding-left: 15px;
	margin-bottom: 0;
}

.paola-1 .paolacontent-cell ul li:before {
	color: #B2D234;
	vertical-align: middle;
}

.paola-1 .patient-baseline .ftnote1.footnote p:last-child {
	margin-top: 20px;
}

.paola-1 .piechart-content p {
	font-size: 16px;
	font-family: 'Roboto-Bold';
	color: #004D74;
	font-style: italic;
}

.paola-1 .women-callout {
	transform: skewX(-8deg);
	background-color: #B2D234;
	color: #fff;
	font-family: 'Roboto-Bold';
	color: #004D74;
	padding: 10px;
	text-align: center;
	margin-top: 35px;
}
.paola-1 .women-callout .normal{font-style: initial;}
.paola-1 .women-callout p {
	font-size: 15px;
	line-height: 18px;
	margin-bottom: 0;
        transform: skewX(8deg);
    font-style: italic;
}
.paola-1 .references {
    margin-bottom: 45px;
}
.paola-1 .hrd-positive .ftnote1.footnote p:last-child {
	margin-top: 20px;
}

.patient-baseline .calloutDemographics{
    background: #FFE6CB;
    border-left: 6px solid #F7931D;
    width: 80%;
    margin: 40px auto;
    text-align: left;
    transform: skewX(-10deg);
    padding: 1.5% 5.5% 1.5% 2.5%;
}

.patient-baseline .calloutDemographics p, 
.patient-baseline .calloutDemographics h2{
    transform: skewX(8deg);
        margin-bottom: 0;
}
.abbrevation .footnote.ftnote1 {
    margin-top: -10px;
}
.patient-baseline .hrdPositiveChart{
    display: flex;
    flex-direction: column;
    margin: 35px 0;
}
.patient-baseline .hrdPositiveChartLhs h3 {
    font-family: 'Roboto-Medium';
    color: #004D74;
    font-style: italic;
    font-size: 21px;
    margin: 30px 0;
}

.patient-baseline .hrdPositiveChartLhs p {
    font-family: 'Roboto-Medium';
    color: #004D74;
    font-size: 17px;
    line-height: 20px;	
}

.patient-baseline .patient-baselineH3 {
    font-size: 17px;
}

.paola-1 .patient-baseline .ftnote2.footnote {
    margin: 20px 0 0 0;
}

.bevacizumabChartHead{ margin-top: 30px; }

.patient-baseline .font-bold{
	font-family: "Roboto-Bold";
    }

.paola-graph-func .bevacizumabChart {
    max-width: 100%;
    margin: 10px auto;
}

.paola-1 .paola-graph-func h3 {
    line-height: 22px;
    font-family: Roboto-bold;
    color: #004D74;
    font-size: 18px;
}

.paola-graph-func .hrdSubgroup {
    border: 2px solid #b2d234;
    border-left: none;
    border-right: none;
    padding: 20px 25px 10px 25px;
    margin: 30px 0;
}

.paola-graph-func .hrdSubgroup p {
    font-size: 16px;
	line-height: 22px;
}

.paola-graph-func .hrdSubgroupAdditional {
    padding: 0 25px;
}

.paola-graph-func .hrdSubgroup p span.blue-text {
    font-family: 'Roboto-Bold';    
    color: #004D74;
}
.paola-graph-func .hrdSubgroupHead, .paola-graph-func ul.subGroupList li p span{
    font-family: 'Roboto-Bold';
}

.paola-graph-func ul.subGroupList{
    margin:20px 0;
} 

.patient-baseline .calloutDemographics .footnote.ftnote1 {
    transform: skewX(10deg);
    padding: 0 0 0 9px;
    margin: 10px 0 0 0;
}

.paola-1 .font-normal {
	font-style: normal;
}

.paola-1 .font-bold {
	font-family: "Roboto-Bold";
}
.isi-body strong {
	font-family: "Roboto-Bold";
}

/*------------END OF EFFICACYPAOLA-1-----------------*/

@media only screen and (min-width: 1024px) {
 ul.sub-list li {
    line-height: 22px;
}
    span.note img {
        margin-left: -14px;
    }
        .recommend_content {
        margin: 20px 0 0px 7.8%;
    }
    .HRD-Testingv2  .recommend_content {
        margin: 20px 0 20px 7.8%;
    }
    .callout-block {
    margin: 20px 10px;
    }
	.hrd-testing .grid-section {
		max-width: 91%;
		margin: 0 auto;
		display: flex;
		padding-bottom: 30px;
		padding-top: 25px;
	}
	.hrd-testing .grid-section .section-collect.female_icon {
		margin: 0 30px 0 0;
	}
	.hrd-testing .section-collect span:first-child img {
		margin: 0 auto;
	}
	.hrd-testing .section-collect span:last-child {
		width: 57%;
		margin: 0px auto;
		text-align: center;
		display: block;
		position: relative;
		top: 16px;
	}
	.hrd-testing .section-collect.female_icon span:last-child {
		padding: 0;
	}

    .grid-section .tumor-icon{
        width: 25%;
          position: relative;
    }
    .tumor-icon .left-img {
        height: 129px;    
        margin-top: 0px;
        display: flex;
        align-items: center;
        justify-content: center;
    }

    .tumor-icon:after{
            content: "";
        background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-oc/desktop/d_global_right_arrow_green.png);
        background-size: cover;
        width: 18px;
        height: 38px;
        position: absolute;
        top: 44px;
        right: 0;
    }
    .tumor-icon.four:after{
        display: none;
    }

    .tumor-icon .left-img img{
        max-width: 67px;
    }

    .tumor-icon.second .left-img img{
         max-width: 84px;
    }

    .tumor-icon.four .left-img img{
        max-width: 92px;
    }

    .tumor-icon .right-text p{
        text-align: center;
        padding: 0;
        margin: 0;
            margin-top: 20px;
    }

    .tumor-icon .right-text p span{
        display: block;
    }
	.hrd-testing .section-collect span:first-child {
		display: block;
		width: 35%;
		margin: 0 auto;
	}
	.hrd-testing .collect {
		padding-top: 20px;
    	font-size: 16px;
	}
	.hrd-testing .section-collect span.note {
		width: 45%;
	}
	.hrd-testing .unprecedented-efficacy .why-tumor h2 {
		padding-top: 3px;
	}
	.hrd-testing .container-center.content-inner-wrapper.issue {
		padding-bottom: 0;
	}
	.hrd-testing .section-collect.tissue span.collect {
		top: 25px;
	}
	.hrd-testing .section-collect.tissue {
		width: 33%;
	}
    .block-two .list-capsule{
        margin-bottom: 28px;
    }
	/*------------START OF EFFICACYPAOLA-1-----------------*/


	.paola-1 .paolaimg-cell {
		/*display: flex;
		width: 79%;*/
		padding: 0 23px 0 0;
	}
	.paola-1 .paolaimg-cell p.footnote {
	    display: block;
    	margin: 20px 0 0 238px;
    	line-height: 17px;
	}
	.paola-1 .paolaimg-cell p.footnote span.indent {
		text-indent: -6px;
		display: inline-block;
	}
	.paola-1 .paolaimg-cell div.footnote p:nth-child(2) {
		margin-top: 20px;
	}
	.paola-1 .imgcontent-table {
		display: flex;
	}
	.paola-1 li.horline p {
		margin: 15px 0 0 0;
		font-family: 'Roboto-Regular';
	}
	.paola-1 li.horline ul.sub-list p{
    	margin: 15px 0 0 -12px;
	}
	.paola-1 .key-criteria {
		margin-left: 5%;
	}
	.paola-1 .paola-enrolled .circle {
		margin-top: 8px;
	}
.paola-1 .patient-baseline .ftnote1.footnote.ecog {
    margin: 35px auto 4px auto;
}
	.paola-1 .patient-baseline .ftnote1.footnote {
    width: 826px;
    margin: 5px auto 4px auto;
    max-width: 100%;
}
    .paola-1 .patient-baseline .hrdPositiveChartLhs  .ftnote1.footnote{
        width:auto;
		margin: 20px 0 0 0;                                        
     }                
    .patient-baseline img.desktop {
        max-width: 100%;
        margin: 0 auto;
    width:82%;
    }

	.patient-baseline .calloutDemographics p {
    color: #004D74;
    font-family: 'Roboto-Bold';
    font-size: 22px;
    line-height: 26px;
}
	.patient-baseline .hrdPositiveChart{
    	margin: 40px 0;
    	flex-direction: row;
	}
	.patient-baseline .hrdPositiveChartLhs{
    	width: 50%;
    	margin: 0 5% 0 9%;
    }
	.paola-1 .paola-graph-func p.eyebrow{width:80%}
	.paola-graph-func .calloutGreenBg{float: left;
    width:42%;
    margin: 7px 25px 0 0;}
	.paola-1 .paola-graph-func h3{
        line-height: 32px;
        font-size: 22px;
        margin-top: 30px;
    }
.paola-graph-func .graph-study{

    margin-top:23px;
    position: relative;
    top: 28px;
}
	.patient-baseline .patient-baselineH3{ font-size: 17px;    width: 82%;    margin: 0 auto; }
        .bevacizumabChartHead{ margin-top: 10px; }
	/*.paola-graph-func .bevacizumabChart{    max-width: 100%; margin: 0 auto; }*/
	.paola-1 .patient-baseline .ftnote2.footnote{
        margin: 20px auto 0 auto;
        width: 82%;
    }

    .patient-baseline .hrdPositiveChartLhs h3{margin: 18px 0;}
    /*.patient-baseline .hrdPositiveChartLhs p{font-family: 'Roboto-Bold'; color:#004D74; font-size: 17px;}*/
	.patient-baseline .hrdPositiveChartRhs{
    	width: 40%;
	}
	/*.paola-graph-func .hrdSubgroup {
        border: 1px solid #b2d234;
        border-left: none;
        border-right: none;
        padding: 20px 25px;
        margin: 30px 0;
    }

    .paola-graph-func .hrdSubgroup p span{
        font-family: 'Roboto-Bold';    
        color: #004D74;
    }
    .paola-graph-func .hrdSubgroupHead, .paola-graph-func ul.subGroupList li p span{
        font-family: 'Roboto-Bold';
    }

    .paola-graph-func ul.subGroupList{
        margin:20px 0;
    } */
	.paola-1 p.key {
		font-size: 20px;
		padding: 0px 0px 12px 8%;
	}
	.paola-1 .hrd-positive h2,
	.paola-1 .patient-baseline h2,
	.paola-1 .paola-study h2,
	.paola-1 .paola-enrolled h2 {
		font-size: 25px;
		line-height: 30px;
		margin-bottom: 25px;
		margin-top: 4px;
	}
    .patient-baseline .calloutDemographics h2 {
        margin: 0;
    }
	.paola-1 p.patient-enrolled {
		font-size: 20px;
		margin-bottom: 25px;
        margin-top: 5px;
	}
	.paola-1 li.horline {
		margin: 25px 0px;
		padding: 0 0 25px 22px;
    	width: 95%;
	}
	.paola-1 .sub-head p {
		font-size: 20px;
		line-height: 22px;
	}
	/*.paola-1 .sub-head p span.myriad-choice {
		background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-oc/desktop/my-choice-cdx-logo.png);
		width: 181px;
		height: 40px;
		display: inline-block;
		vertical-align: middle;
		background-size: 100%;
		mix-blend-mode: multiply;
	}*/
	.paola-1 img.paola-img {
		float: left;
		margin: 8px 10px 0px 0px;
	}
	.paola-1 .ftnote1.footnote p {
		font-size: 14px;
		line-height: 17px;
	}
	.split{
          width:75%;
                }
	.paola-1 .pie-charthrd {
		display: flex;
		position: relative;
		margin-top: 35px;
	}

	.paola-1 .piechart-content {
		max-width: 55%;
	}

    .paola-1 .women-callout p {
        font-size: 18px;
        line-height: 22px;
        margin-bottom: 0;
        text-align: left;
    }

	.paola-1 .piechart-content p {
		font-size: 18px;
		max-width: 68%;
		margin-left: 15%;
	}

	.paola-1 .women-hrd {
		position: absolute;
		margin-top: -9%;
	}

	.paola-1 .women-callout {
        max-width: 38%;
        margin-left: 10%;
        padding: 12px 18px;
	}
    .paola-graph-func .bevacizumabChart {
    margin: 75px auto 10px auto;
    display: block;
}
.patient-baseline .calloutDemographics {width:75%;}
	/*------------END OF EFFICACYPAOLA-1-----------------*/
}



@media (max-width: 1023px) {
.paola-graph-func .bevacizumabChart {
    max-width: initial;
    margin: 30px auto;
}
        .paola-graph-func .bevacizumabChart.mobile {width:100%;}

.paola-study img.mobile {
    max-width: 100%;
    margin-bottom: 30px;
    margin:0 auto;
}
.paola-1 .paola-graph-func h2, .paola-1 .paola-graph-func .bevacizumabChartHead h3 {
    line-height: 25px;
    font-size: 22px;
}

.scroll-more.mobile p {
    font-size: 10px;
    font-family: 'Roboto-Light';
}

        .patient-baseline .calloutDemographics{padding: 4% 7% 4% 4%;width:95%;transform:skewX(-8deg);}
        .patient-baseline .calloutDemographics h2{margin:0}

.mCSB_horizontal.mCSB_inside > .mCSB_container {
    padding: 0 0 20px 0;
}


.patient-baseline .patient-baselineH3 {
    font-size: 16px;
    line-height: 20px;
}

.paola-1 li.horline {
    padding: 0 0 15px 21px;
    font-size: 15px;
    border-bottom: 1px solid #333;
}

    .paola-1 ul.sub-list p{
        margin: 0 0 0 -20px;
    }

    .paola-1 .paolacontent-cell .paolacontent-cell-1{ width: 90%;}        

.paola-1 ul.sub-list li.sub-list {
        font-size: 13px;
}    

.patient-baseline .calloutDemographics .footnote.ftnote1 {
    padding: 0 0 0 10px;
}

.hrdPositiveChart .hrdPositiveChartLhs{order:2;}
.hrdPositiveChart .hrdPositiveChartRhs{order:1;}
.hrdPositiveChart .hrdPositiveChartRhs img{margin: 0 auto; max-width:100%;}

.paola-1 .paola-study h2{text-align:left;}
.paola-1 .paolaimg-cell p.footnote span.indent {
    text-indent: -5px;
    display: inline-block;
}
.paola-1 .heading {
    margin-bottom: 15px;
}
.daignosis-block .tissue-order {
    padding-bottom: 15px;
}
.callout-block p {
font-size: 15px;
    line-height: 18px;
    }
	/*img.mark-img { max-width: 6.7%; margin-top: -5%; left: 3%;}*/
	.paolacontent-cell li,
	.key-criteria li,
	.paola-1 p,
	.hrd-testing p {
		font-size: 16px;
		line-height: 20px;
	}
	.hrd-testing .common-headline h3 {
		font-size: 17px;
		line-height: 18px;
	}
	.hrd-testing .section-collect {
		display: flex;
	}
	.hrd-testing .section-collect span:nth-child(2) img {
		width: 63%;
		margin: 0 auto;
	}
	.hrd-testing .section-collect.tissue span:nth-child(2) img {
		width: 63%;
		margin: 0;
	}
	.hrd-testing .section-collect span:nth-child(3) {
		position: relative;
		top: 15px;
		width: 191px;
	}
	.hrd-testing .down-img img {
		margin: 0 auto;
		position: relative;
		top: 16px;
		margin-top: 18px;
		margin-bottom: 30px;
	}
	.hrd-testing .promptly {
		margin-left: 17px;
	}
	.hrd-testing .grid-section {
		margin-bottom: 25px;
		margin-top: 35px;
        margin-left: -4%;
	}
	.hrd-testing .breaking {
		display: inline-block;
	}
.hrd-testing .breakingblock {
		display: block;
	}
	.hrd-testing .unprecedented-efficacy p:first-child {
		color: #333;
	}
	.hrd-testing .link-bg a {
		position: relative;
		left: 0px;
	}
	.hrd-testing .arrow-img {
		background-position: 290px center;
	}
	.hrd-testing .unprecedented-efficacy .content-section p:first-child {
		padding-top: 13px;
		color: #fff;
	}
	.hrd-testing .solo-heading h1 {
		width: 100%;
		margin: auto;
	}


.grid-section .tumor-icon{
    padding-bottom: 77px;	
      position: relative;
    max-width: 375px;
    margin: 0 auto;
}

.grid-section .tumor-icon.four{
  padding-bottom: 0px;
}
.tumor-icon .left-img {

    margin-top: 0px;
    display: flex;
    align-items: center;
    justify-content: center;
}

.tumor-icon:after{
	    content: "";
    background-image: url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-oc/mobile/m_global_down_arrow_green.png);
    background-size: cover;
    width: 38px;
    height: 18px;
    position: absolute;
  bottom: 32px;
    left: 44%;
}
.tumor-icon.four:after{
	display: none;
}

.tumor-icon .left-img img{
    max-width: 70px;
}

.tumor-icon.second .left-img img{
     max-width: 93px;
}
.tumor-icon.third .left-img img{
     max-width: 74px;
}
.tumor-icon.four .left-img img{
    max-width: 86px;
}

.tumor-icon .right-text p{
    text-align: center;
    padding: 0;
    margin: 0;
        margin-top: 20px;
}
.tumor-icon .right-text{
     max-width: 242px;
    margin: 0 auto;
}


	/*------------START OF EFFICACYPAOLA-1-----------------*/
	/*.paola-1 #maincontent .patient-baseline .image-scroll .image-scroll-inner {
        width: 616px;
        height: 440px;
    }*/

	.paola-1 .paolacontent-cell .paolacontent-cell-2 {
        margin-top: 30px;
    }

	.paola-1 .paolacontent-cell {
        padding: 30px 0 0 0;
    }

	.paola-1 .sub-head p {
		max-width: 81%;
		margin: 0 auto;
		text-align: left;
	}
	.paola-1 .ftnote1.footnote {
        margin-top: 25px;
    }
	.paola-1 .sub-head p span.myriad-choice {
        background-size: 80%;
    }
.paola-study img.mobile {margin-bottom:30px;}
	/*------------END OF EFFICACYPAOLA-1-----------------*/

.patient-baseline .hrdPositiveChartLhs h3{margin: 23px 0;}

}

@media (max-width: 767px) {
.space-out li{
	line-height:20px !important;
    }
.block-one span.note img {
    margin-left: 0px;
    width:100%;
}
.block-one span.note img:nth-child(2) {
    margin-top: -20px;
}
sup.topr {
    position: relative;
    top: -8px;
}
.footer p {
    font-size: 12px;
}
.paolacontent-cell li,
	.key-criteria li,
	.paola-1 p,
	.hrd-testing p {
		/*font-size: 13px;*/
		/*line-height:16px;*/
	}
.rec-icon img {
    margin-left: 20px;
}
	img.mark-img {
		margin: -40px -40px -40px -20px;
	}
	.hrd-testing .grid-section {

		    margin-left: -4%;
		padding-bottom: 14px;
	}
	.hrd-testing .down-img img {
		top: 12px;
		left: 5px;
		width: 16%;
	}
	.hrd-testing h3.bold.nccn-clinic {
		line-height: 18px;
		font-size: 15px;
		margin-bottom: 5px;
	}
	.hrd-testing .partner {
		margin-top: 20px;
		margin-bottom: 20px;
	}
	.hrd-testing .solo-heading h1 {
		width: 100%;
		margin: 0 auto;
	}
	.hrd-testing .why-tumor {
		max-width: 90%;
		margin: 0 auto;
	}
	.hrd-testing .arrow-img {
		background-position: 265px center;
		background-size: 17px;
	}
	.hrd-testing .germline {
		padding: 7px 88px 9px 19px;
		transform: skew(10deg);
		max-width: 100%;
	}
	.hrd-testing .link-bg a {
		position: relative;
		left: 0px;
		height: 62px;
	}
	.hrd-testing .link-bg a:active {
		height: 62px;
		border: solid 3px #004D74;
	}
	.hrd-testing .why-tumor h2 {
		margin-bottom: 40px;
	}
	.hrd-testing .section-collect .collect {
		top: 4px !important;
		left: -8px;
	}
	.hrd-testing .section-collect .collect.receive {
		top: 18px !important;
		left: 3px;
	}
	.hrd-testing .section-collect.female_icon .collect.receive {
		top: 42px !important;
		left: 28px;
	}
	.hrd-testing .section-collect .promptly {
		top: 24px !important;
	}
	.hrd-testing .consider-testing {
		padding-bottom: 5px;
	}
	.hrd-testing .content-section-nccn {
		padding-bottom: 45px;
	}
	.hrd-testing .section-collect span.promptly {
		width: 65%;
	}
     .patient-baseline .calloutDemographics p {
    color: #004D74;
        }
	/*------------START OF EFFICACYPAOLA-1-----------------*/
	.paola-1 img.paola-img {
		margin: 0 auto 15px auto;
		display: block;
	}
	.paola-1 img.mobile.mCS_img_loaded {
		margin-top: 20px;
	}
	.paola-1 .hrd-positive h2 {
		margin-bottom: 30px;
	}
	.piechart-content {
		padding-bottom: 30px;
	}
   .piechart-img img {
    max-width: 100%;
}
	.paola-study img.mobile {
		max-width: 100%;
		margin-bottom: 30px;
	}

.patient-baseline .hrdPositiveChartLhs h3{margin: 22px 0;}
	/*------------END OF EFFICACYPAOLA-1-----------------*/
}

@media only screen and (min-width: 768px) and (max-width: 1024px) {
	/*img.mark-img {
    max-width: 5%;
    margin-top: -3.5%;
    left: 1.5%;
}
    .paola-1 .sub-head p {
    max-width: 84%;
            }*/
            .paola-1 .paola-img {
    margin: 7px 10px 15px 290px;
    display: block;
}
.callout-block p {
    line-height: 26px;
    font-size: 20px;
}
.olaprib_cat,.nccn_clinical {
    padding-left: 22%;
}
.block-one p.block-one-text {margin-top:15px;}

.paola-graph-func .calloutGreenBg {
    width: 75%;
    margin-bottom: 15px;
}

}

@media only screen and (min-device-width: 768px) and (max-device-width: 1024px) and (orientation: landscape) {
    .paola-1 .sub-head p {
    max-width: 95%;
}
    .block-one span.note img {
    margin-left: 5px;
    width:100%;
}
    .paola-1 .women-hrd {
    position: absolute;
    margin-top: -12%;
}
    .olaprib_cat, .nccn_clinical {
    padding-left: 15%;
}
}

@media only screen and (min-device-width: 768px) and (max-device-width: 1024px) and (orientation: portrait) {
    .paola-1 .sub-head p {
    max-width: 88.5%;
}
.paola-graph-func .calloutGreenBg{
           width:75% !important ;
           margin-bottom: 15px;
        }
    .block-one span.note img {
    margin: 25px auto;
}
            .scroll-more.mobile p {
    padding: 0;
    font-style: italic;
    margin: 0;
    /*display:none;*/
}
 .paola-1 .imgcontent-table {
    
    margin: 0 auto;
}
 .paola-1 .piechart-content {
    margin: 30px 0;
}
 .paola-1 .piechart-img {
    margin: 0 auto;
    max-width: 50%;
}
 .paola-1 .women-callout {
    padding: 10px 20px;
 }
.paola-1 #maincontent .patient-baseline .image-scroll .image-scroll-inner {margin:0 auto;}
.paola-1 #maincontent .patient-baseline .scroll-more.mobile {display:none!important;}
.patient-baseline .image-scroll-inner {text-align:center;}
.patient-baseline .scroll-more {display:none!important;}

}

@media (max-width: 767px) {
.paola-graph-func .calloutGreenBg{
	width:100%  !important ;
        }
.paola-graph-func .graph-study{
       /* width:100%;*/

    margin: 27px 0 -6px 0;
} 
.HRD-Testingv2 .recommend_content {
    margin: 25px 0 30px -39px;
}

.scroll-more p{
margin:0px;
}
.HRD-Testingv2 .image-scroll .image-scroll-inner {
    width: 939px;
    height: 781px;
}
.block-one p.block-one-text {
	font-size: 13px;
	line-height: 16px;
}
.block-one p{
    padding: 0px 0 0px 0px;
}
.block-three .three {
    margin: 38px 0px 0px 23px;
}
.block-three .tissue-order .list-capsule {
    margin-left: 0px;
}
.tissue-order {
    margin-left: -32px;
    }

.daignosis-block .block-three .tissue-order {
    margin: 20px 0 0 -30px;
}
.daignosis-block .block-three .tissue-order .footnote{
    margin: 0px 0 0 30px;

}
.tissue-order {
    font-size: 13px;
	line-height: 16px;
}
.callout-block{
	left: 10px;
    max-width: 90%;
    position: relative;
    transform: skewX(-7deg);
    padding: 15px;
    text-align: center;
    border-width: 5px;
}
.callout-block p {
	transform: skewX(7deg);
}
    .recommend_content {
    margin: 0 0 0 -30px;
}

.daignosis-block .tissue-order {
    padding-bottom: 15px;
}
.nccn_clinical {
    padding-top: 35px;
    padding-left: 148px;
    margin-right: 46px;
}

.olaprib_cat {
    padding-top:50px;
    padding-left: 20px;
}
    .HRD-Testingv2 .callout-block p{
    font-size: 15px;
    width: 92%;
    padding-left: 8%;
    }
    .HRD-Testingv2 .callout-block p{
    width: 94% !important;
    padding-left: 5% !important;
    }
.paola-graph-func .hrdSubgroup p {
    font-size: 13px;
}
}
@media screen and (-ms-high-contrast: active), (-ms-high-contrast: none) {
    .block-one span.note img {width:100%;}
.paola-1 .sub-head p span.myriad-choice {background-image:url(/content/dam/physician-services/us/590-lynparza-hcp-branded/hcp-oc/desktop/my-choice-cdx-logo-ie.png);background-position:0px 0px;opacity:.4;}

}

@-moz-document url-prefix() {.block-one span.note img {width:100%;} }


@media screen and (min-width: 767px) and (max-width: 768px)  {/*
.paola-graph-func .calloutGreenBg{
	width:100%  !important ;
        }*/
    .paola-graph-func .calloutGreenBg{
           width:75% !important ;
           margin-bottom: 15px;
        }
.paola-graph-func .graph-study{
       /* width:100%;*/

    margin: 27px 0 -6px 0;
}            
    }
@media screen and (min-device-width: 481px) and (max-device-width: 1024px) and (orientation:portrait) {
img.graph-study{
    margin: 7px 0 -6px 0;
    width:70%
    }
}

@media only screen and (max-width:360px)(orientation :portrait){
    .iphone5-nowrap{
		white-space: nowrap;

        }
}
    @media only screen and (min-width: 320px) and (orientation :portrait){
    .iphone5-nowrap{
		white-space: nowrap;

        }
}
@media(max-width: 375px){
.paola-1 .paolacontent-cell .paolacontent-cell-2 {
    	padding: 15px 10px;
	}
  }