/*/safety-about*/

/*common css */

.bar span.w-3-3 {
  width: 3.3%;
}

.bar span.w-1-8 {
  width: 1.8%;
}

.bar span.w-2-3 {
  width: 2.3%;
}

.bar span.w-0-3 {
  width: 0.3%;
}

.bar span.w-0-5 {
  width: 0.5%;
}

.bar span.w-1-2 {
  width: 1.2%;
}

.bar span.w-1-3 {
  width: 1.3%;
}

.bar span.w-97 {
  width: 97%;
}

.bar span.w-81 {
  width: 81%;
}

.bar span.w-49 {
  width: 49%;
}

.bar span.w-46 {
  width: 46%;
}

.bar span.w-98 {
  width: 98%;
}

.bar span.w-73 {
  width: 73%;
}

.bar span.w-62 {
  width: 62%;
}

.text-center {
  text-align: center;
}

.subheading {
  font-family: "roboto", sans-serif;
  font-weight: 700;
}

.cta-button a.blue-color {
  border: 5px solid #004D74;
  background-color: #B5CCD8;
}

.blue-bg {
  background-color: #004D74;
}

.mobile-view-only {
  display: block;
}

.desktop-view-only {
  display: none;
}

.cta-button.desktop-view-only {
  display: none;
}

.cta-button.mobile-view-only {
  text-align: center;
  display: inline-block;
}
  

/*common css end */
#inner-content {
 font-family: "roboto", sans-serif;
  font-weight: 400;
  line-height: 1.42857143;
  padding: 0 20px;
  margin: 0 auto;
}

#testing-inner {
  font-family: "roboto", sans-serif;
  font-weight: 400;
  line-height: 1.42857143;
  font-size: 16px;
  color: #000;
}

.cmp-text {
  font-family: "roboto", sans-serif !important;
}

#headTable h2 {
  font-family: "roboto", sans-serif;
  font-weight: 700;
  font-size: 20px;
  line-height: 26px;
  color: #004d74;
  margin: 0 auto;
  margin-top: 27px;
}

#inner-content .footnote {
  font-family: "roboto", sans-serif;
  font-weight: 400;
  color: #000000;
}
#pr-efficacy-combination-therapy .cta-button a {
    padding: 15px 22px;
}

#headTable .neww-table {
  margin: 18px auto 0px;
}

#headTable .safety-study-section, #headTable .safety-bar-table {
  margin: 0;
}

#headTable .safety-study-section .safety-legend ul {
  padding: 0;
  margin-top: 0;
  margin-bottom: 5px;
  margin-right: 7px;
}

#headTable .safety-study-section .safety-legend ul li {
  font-size: 9px;
  margin-left: 0;
  margin-bottom: 2px;
  line-height: inherit;
}

#headTable .safety-legend ul li:first-child span, #headTable .safety-bar-table ul.chart li:first-child .bar span {
  background-color: #B2D234;
}

#headTable .safety-legend ul li span {
  width: 18px;
  height: 18px;
}

#headTable .neww-table th {
  font-size: 11px;
  line-height: 16px;
  letter-spacing: -0.4px;
}

#headTable .neww-table tr:first-child th {
  border-bottom: 3px solid #56849f;
}

#pr-main-container #headTable .neww-table td,#pr-main-container .neww-table th {
  padding: 5px 8px;
}

#headTable .neww-table tr:first-child th:first-child {
  padding-top: 12px;
  padding-bottom: 12px;
}

#headTable .safety-bar-table th {
  text-align: left;
}

#headTable .neww-table tr:first-child th {
  text-align: center;
}

#headTable .safety-bar-table .neww-table tr:first-child th:first-child {
  text-align: left;
}

#headTable .neww-table td {
  font-size: 14px;
  line-height: 21px;
}

#headTable .val {
  font-family: "roboto", sans-serif;
  font-weight: 700;
  font-size: 10px;
  line-height: 12px;
}

#headTable .safety-bar-table .reaction-name.pad-40 {
  padding-left: 20px;
}

#headTable .neww-table .reaction-name {
  font-size: 10px;
  line-height: 12px;
}

#inner-content .footnotecontiner.container-center {
  margin-top: 10px;
}

#inner-content .footnote.footnote-color {
  font-family: "roboto", sans-serif;
  font-weight: 400;
  color: #333333;
  font-size: 12px;
  line-height: 14px;
  text-indent: 0px;
  margin-bottom: 3px;
}

#inner-content .footnote .indent-1 {
  text-indent: -5px;
  display: inline-block;
  width: 0;
}

#inner-content .container-center {
  padding: 0;
}

#inner-content .container-center.safetylistsect {
  margin-top: 15px;
  margin-bottom: 34px;
  padding-left: 4px;
}

#inner-content .container-center.safetylistsect ul {
  line-height: 18px;
  font-size: 14px;
  color: #333333;
}

#inner-content .container-center.safetylistsect ul li {
  margin-top: 5px;
  margin-bottom: 5px;
  list-style-type: none;
  text-indent: -5px;
}

#inner-content .safetylistsect ul li:before {
  content: "•";
  font-size: 16px;
  position: relative;
  left: -5px;
}

#inner-content .safetylistsect li span.left3 {
  left: -3px;
  position: relative;
}

#inner-content .container-center.safetylistsect ul li:nth-of-type(3) {
  margin-top: 8px;
}

#inner-content .heading.blue-color.ff-roboto-bold {
  font-size: 20px;
  line-height: 22px;
  margin: 8px 0 16px;
}

#inner-content .dose-modification-safety-update table tr td {
  padding-top: 4px;
  padding-bottom: 4px;
}

#inner-content .dose-modification-safety-update table tr td:first-child {
  font-size: 13px;
  padding-right: 30px;
  line-height: 13px;
  padding-left: 6.5px;
}

#inner-content .dose-modification-safety-update table tr:first-child td:first-child {
  padding-bottom: 0;
  padding-top: 0;
}

#inner-content .dose-modification-safety-update table tr:first-child td:last-child {
  font-size: 12px;
  line-height: 10px;
  padding: 12px 0px 14px;
}

#inner-content .dose-modification-safety-update table tr td.green-shade-bg {
  font-size: 12px;
  line-height: 9px;
  padding: 12px 75px 14px;
  background-color: #F7FAEA;
}

#inner-content .dose-modification-safety-update table+p {
  font-size: 16px;
  line-height: 20px;
  margin: 16px 0 18px;
  font-family: "roboto", sans-serif;
  font-weight: 400;
}

#inner-content .dose-modification-safety-update>div:last-child {
  transform: skew(0);
  margin: 0;
  text-align: left;
  margin-bottom: 44px;
}

#inner-content .dose-modification-safety-update>div:last-child>p {
  font-size: 20px;
  line-height: 28px;
  transform: skew(0);
  padding: 10px 0px 10px 8px;
}

#inner-content .dose-modification-safety-update>div:last-child {
  background-color: #F5E5EF;
  max-width: 905px;
  border-left: 9px solid #990064;
}

#inner-content .tbl-section-two .footnotecontiner.container-center {
  margin-top: 20px;
}

.cta-margin .cta-button {
  max-width: none;
}

.propel-content .cta-margin .cta-button {
  max-width: none;
  display: flex;
  justify-content: center;
}

#pr-main-container .cta-button {
  justify-content: center;
  text-align: right;
  width: 100%;
  display: flex;
}

.cta-button>div {
  max-width: fit-content;
}

.cta-button a {
  border: 5px solid #990064;
  max-width: fit-content;
  width: 100%;
  display: inline-block;
  text-align: center;
  padding: 15px 19px;
  background: #D9B9CA;
  font-size: 20px;
  line-height: 20px;
  text-decoration: none;
}

#pr-patient-profiles #pr-main-container .cta-button a:after ,
#pr-moa #pr-main-container .cta-button a:after ,
#pr-nccn-guidelines #pr-main-container .cta-button a:after {
  content: "";
  display: inline-block;
  width: 14px;
  height: 14px;
  border: 4px solid;
  transform: rotate(45deg);
  border-left: none;
  border-bottom: none;
}

.cta-button a.pink-color:hover {
  text-decoration: none;
  background-color: #990064;
  color: #fff;
}

#pr-patient-profiles .cta-button a.pink-color:hover {
  background-color: #990064;
}

.cta-button a.blue-color {
  border: 5px solid #004D74;
  background-color: #B5CCD8;
  color: #004D74;
}

.cta-button a.blue-color:hover {
  color: #fff;
  text-decoration: none;
  background-color: #004D74;
}

.blue-color {
  color: #004D74;
}

/*Monotherapy start */
#pr-safety-combination-therapy .propel-content .cta-button a {
  padding: 15px 13px;
}

#pr-safety-combination-therapy .propel-content .cta-button a:after {
  margin-left: 15px;
}

#pr-safety-combination-therapy .propel-content .cta-margin {
  margin-top: 24px;
  margin-left: -10px;
}

#pr-safety-monotherapy #headTable h2 {
  margin-top: 35px;
}

#pr-safety-monotherapy .safety-legend ul li {
  flex-direction: row-reverse;
}

#pr-safety-monotherapy .safety-legend ul li span {
  margin-right: 0px;
  margin-left: 8px;
}

#pr-safety-monotherapy #inner-content .container-center {
  padding-left: 4px;
}

#pr-safety-monotherapy #inner-content .container-center.safetylistsect {
  padding-left: 8px;
}

#pr-safety-monotherapy #inner-content .safetylistsect ul li:before {
  content: "•";
  font-size: 24px;
  position: relative;
  left: -5px;
  bottom: -4px;
}

#pr-safety-monotherapy #headTable #sfTableTwo h2 {
  margin-top: 55px;
}

#pr-safety-monotherapy .monotherapy-footnote.mar-top {
  margin-bottom: 10px;
}

#pr-safety-monotherapy #inner-content .monotherapy-footnote {
  color: #333333;
  font-size: 12px;
  line-height: 15px;
}

#pr-safety-monotherapy .propel-content .cta-margin {
  margin-top: 40px;
  left: -7px;
  position: relative;
}
 #pr-safety-monotherapy .pr-hero__container .pink-bg{
     padding: 20px;
 }
#pr-safety-monotherapy .propel-content .cta-margin .cta-button a {
  padding: 17px;
}

#pr-safety-monotherapy .cta-button a:after {
  margin-left: 15px;
}

#pr-safety-monotherapy #inner-content .tbl-section-two .footnotecontiner.container-center {
  padding-left: 5px;
}
#pr-safety-monotherapy #inner-content .footnotecontiner.container-center{
        margin-top: 15px;
    }

#pr-safety-monotherapy #inner-content .container-center.safetylistsect ul li:nth-of-type(3) {
        margin-top: 21px;
    }
.propel-content-testing .container-center {
     padding-left: 0; 
    padding-right: 0;
    }

/*Mechanism of action */
#pr-moa .moa-combi .sect-1 .heading-1 {
  margin-top: 20px;
}

#pr-moa .heading-1 {
  font-family: "roboto", sans-serif;
  font-weight: 700;
  color: #004D74;
}

#pr-moa  .hp-margin, #pr-moa .hg-margin {
  padding-top: 3px;
  padding-bottom: 3px;
  display: flex;
}

#pr-moa .hp-margin, #pr-moa .hg-margin {
  margin-bottom: 16px;
  clip-path: polygon(0 0, 100% 0%, 96% 100%, 0% 100%);
  background: #990064;
  width: fit-content;
  padding: 3px 15px 3px 10px;
}

#pr-moa .hg-margin {
  background: #004D74;
}

#pr-moa .hp-margin span, #pr-moa .hg-margin span {
  line-height: 18px;
}

#pr-moa span.hc-text-bg {
  font-size: 16px;
      font-family: "futura-pt-web", 'roboto';
  font-weight: 700;
  color: #ffffff;
  letter-spacing: 1.6px;
  font-weight: bold;
  font-style: italic;
}

#pr-moa p.sub-heading.spadd {
  padding-bottom: 18px;
  margin: 0px;
}

#pr-moa .sub-heading {
  color: #2B2E34;
  font-family: "roboto", sans-serif;
  font-weight: 400;
  font-size: 16px;
  line-height: 20px;
}

#pr-moa .sub-heading .bold {
  font-family: "roboto", sans-serif;
  font-weight: 700;
}

#pr-moa .heading-1 h2 {
  font-size: 20px;
  line-height: 24px;
  margin: 0;
  font-family: "roboto", sans-serif;
    font-weight: 700;
}

#pr-moa .img_sec img.mobile {
  max-width: 100%;
}

#pr-moa .img_sec {
  text-align: center;
}

.mobile {
  display: inline-block;
}

.desktop {
  display: none;
}

#pr-moa .moa-combi .sect-1 .heading-1 {
  margin-bottom: 8px;
}

#pr-moa .end-notes {
  margin-bottom: 10px;
  margin-top: 6px;
}

#pr-moa .end-notes .footnotes {
  font-family: "myriad-pro", sans-serif;
  font-weight: 400;
  color: #333333;
  font-size: 12px;
  line-height: 14px;
  margin-bottom: 10px;
}
#pr-moa .pr-hero__container .pink-bg {
       padding: 21px 20px; 
}

.fw-bold {
  font-weight: 700;
}

#pr-moa .end-notes .footnotes.fw-bold {
  font-family: "myriad-pro", sans-serif;
  font-weight: 700;
}

#pr-moa .end-notes p.footnotes:last-child {
  text-indent: 0px;
}

#pr-moa p.sub-heading.spadd-m {
  margin: 0px;
  padding-bottom: 5px;
  margin-top: -5px;
}

#pr-moa .sect-1 .img-cont {
  margin-bottom: 16px;
  margin-left: -5px;
  text-align: center;
}

#pr-moa p.footnote.note-text, #pr-moa p.footnote.subnote-text {
  font-size: 12px;
  line-height: 16px;
}

#pr-moa p.footnote.note-text {
  margin-bottom: 16px;
}

#pr-moa .propel-content, #pr-nccn-guidelines .propel-content {
  margin-top: 24px;
  margin-bottom: 10px;
}

#pr-moa .cta-margin, #pr-nccn-guidelines .cta-margin {
  margin-top: 0px;
}

#pr-moa .propel-content .cta-button a, #pr-nccn-guidelines .propel-content .cta-button a {
  padding: 15px 15px;
}

#pr-moa  .propel-content .cta-button a:after, #pr-nccn-guidelines .propel-content .cta-button a:after {
  margin-left: 15px;
}

#pr-moa  .indent-1, #pr-nccn-guidelines .indent-1 {
  text-indent: -6px;
  display: inline-block;
  width: 0;
}

#pr-moa p.footnote, #pr-moa p.footnotes {
  font-family: "myriad-pro", sans-serif;
  font-weight: 400;
}

#pr-moa p.footnote.fw-bold, #pr-moa p.footnotes.fw-bold {
  font-family: "myriad-pro", sans-serif;
  font-weight: 700;
}

.nccn-table-sec .text-center.first-child {
    padding: 0 0 21px;
}
/*NCCN Guidelines */
#pr-nccn-guidelines #inner-content {
  padding: 0 15px 0 20px;
}
#pr-nccn-guidelines .pr-hero__container .pink-bg {
    padding-left: 20px;
    padding-right: 27px;
}
#pr-nccn-guidelines  .pr-hero__container sup{
    margin-left: 2px;
    font-style: normal;
}

.nccn-mobile-only {
  display: block;
}

.nccn-desktop-only {
  display: none;
}

.nccn-table-sec, .nccn-update-footnote-sec {
  margin: 26px 0 24px;
}

.nccn-table-sec .text-center {
  text-align: left;
  padding: 16px 7px 21px 6px;
}

.nccn-table-sec {
  font-size: 16px;
}

.nccn-table-head {
  font-size: 25px;
  line-height: 28px;
}

.nccn-table-sec td {
  border-left: 1px solid #004D74;
  border-right: none;
}

.nccn-table-inner-head {
  font-size: 18px;
  line-height: 21px;
  padding: 6px 6px;
  letter-spacing: -0.54px;
}

#pr-nccn-guidelines .nccn-table-inner-head {
  padding-right: 51px;
}

.nccn-table-inner-head > p {
  margin: 0;
}

.blue-cell {
  background: #e5edf1;
}

.nccn-body-cell {
  padding: 16px 7px 15px 6px;
  margin: 0;
  width: 100%;
}

.nccn-table-sec tr:nth-child(4) td p {
  padding-bottom: 0;
}

.nccn-body-cell span:nth-child(2) {
  display: block;
}

.nccn-grey {
  color: #57585B;
}

.nccn-table-sec tr:nth-child(5) td {
  border-right: 4px solid #004D74;
}

.nccn-table-sec tr:last-child td p {
  padding-bottom: 0;
}

p.nccn-footnote {
  padding-left: 7px;
}

p.nccn-footnote {
  font-size: 10px;
  line-height: 12px;
  margin: 0;
  color: #525252;
  font-family: "myriad-pro", sans-serif;
    font-weight: 400;
}

p.nccn-footnote.fw-bold {
    font-family: "myriad-pro", sans-serif;
  font-weight: 700;
  margin-bottom: 4px;
  padding-right: 5px;
}

.ast-footnote {
  margin-left: -7px;
}

.single-footnote {
  margin-left: -5px;
}

.nccn-guidelines.lynhcp-pro-integrate .nccn-mono.container-center {
  padding-left: 0;
  padding-right: 0;
}

.nccn-guidelines.lynhcp-pro-integrate .nccn-mono.container-center {
  display: block;
}

#pr-nccn-guidelines .cta-margin {
  margin-top: 40px;
}

.nccn-table-sec tr:nth-child(4) {
  border-bottom: 40px solid #FFFFFF;
}
/*Hypothetical Patient Cases*/
/*#pr-patient-profiles*/
#pr-patient-profiles .section-head p {
  padding: 12px 22px 24px;
}

#pr-patient-profiles .section-head p {
  font-size: 30px;
  line-height: 38px;
  margin: 0;
}

.fs-normal {
  font-style: normal;
}

#pr-patient-profiles .flex-box.patient {
  display: flex;
  flex-direction: column;
  gap: 0;
  column-gap: 54px;
}

#pr-patient-profiles .flex-box.patient .box {
  max-width: 475px;
  width: 100%;
}

#pr-patient-profiles .flex-box.patient .box>* {
  padding-left: 20px;
  padding-right: 20px;
}

#pr-patient-profiles .patient-heading {
  font-size: 22px;
  line-height: 38px;
  margin-bottom: 10px;
}

#pr-patient-profiles .patient-image {
  margin-bottom: 13px;
}

#pr-patient-profiles .patient-details-list  .detaials-list-heading {
  margin: 0;
  font-size: 24px;
  line-height: 38px;
  position: relative;
}

#pr-patient-profiles .detaials-list-heading.pink-ball:before {
  content: "";
  position: absolute;
  width: 23px;
  height: 23px;
  background: #990064;
  left: -33px;
  border-radius: 50%;
  top: 7px;
}

#pr-patient-profiles .patient-details-list ul {
  padding: 0;
  list-style: none;
  margin-bottom: 18px;
}

#pr-patient-profiles .patient-details-list ul li {
  padding-left: 11px;
  position: relative;
  font-size: 20px;
  line-height: 26px;
  font-family: "roboto", sans-serif;
  font-weight: 400;
}

#pr-patient-profiles .patient-details-list ul li:before {
  content: "";
  display: inline-block;
  width: 4px;
  height: 4px;
  background-color: black;
  border-radius: 10px;
  position: absolute;
  top: 10px;
}

#pr-patient-profiles .patient-details-list ul li:before {
  left: 1px;
}

#pr-patient-profiles .patient-details-list ul li ul.patient-details-sublist {
  padding-left: 17px;
  margin-bottom: 0;
}

#pr-patient-profiles .patient-details-list ul li ul.patient-details-sublist {
  margin: 0;
}

#pr-patient-profiles .patient-details-list ul {
  padding: 0;
  list-style: none;
}

#pr-patient-profiles .patient-details-list ul li ul.patient-details-sublist li:before {
  content: "–";
  background: none;
  width: auto;
  height: auto;
  top: 0;
  left: -5px;
 font-family: "roboto", sans-serif;
  font-weight: 400;
}

#pr-patient-profiles .detaials-list-heading.pink-ball:before {
  content: "";
  position: absolute;
  width: 23px;
  height: 23px;
  background: #990064;
  left: -33px;
  border-radius: 50%;
  top: 7px;
}

#pr-patient-profiles .skew-desc {
  max-width: 475px;
  transform: none;
  margin: 6px 0 34px;
}

#pr-patient-profiles .skew-desc p {
  font-size: 18px;
  line-height: 23px;
  text-align: center;
  padding: 16px;
  transform: none;
}

#pr-patient-profiles .cta-button a {
  max-width: 312px;
  padding: 15.5px 0;
  background-color: #F5E6F0;
}

#pr-patient-profiles .cta-button a:after {
  margin: 0 3px;
}

#pr-patient-profiles .cta-button a span {
  display: inline-block;
}

#pr-patient-profiles .pr-combination-therapy .flex-box.patient .box-2 {
  max-width: 466px;
  padding-left: 33px;
  padding-top: 0;
  padding-right: 15px;
}


/*pr-monotherapy */
#pr-patient-profiles .pr-combination-therapy, #pr-patient-profiles .pr-monotherapy {
  margin: 0 auto;
}

#pr-patient-profiles .pr-monotherapy .cta-button a {
  background-color: #004D741A;
}

#pr-patient-profiles .pr-monotherapy .cta-button a:hover {
  background-color: #004D74;
}

#pr-patient-profiles .bg-color {
  background-color: #F3E8EE;
}

#pr-patient-profiles .pr-monotherapy .patient-details-list:has(.pink-ball) {
  padding-left: 53px;
  padding-right: 34px;
}

#pr-patient-profiles .flex-box.patient .cta-button.mobile-view-only {
  margin-bottom: 40px;
}
#testing-inner .section-2 .section-2-content>h2 {
    margin-bottom: 10px;
}
 #pr-main-container .cta-button.desktop-view-only {
    display: none;
}
 /*.nccn-table-sec tr:last-child td:first-child {*/
 /*       vertical-align: top;*/
 /*   }*/
    #pr-moa p.footnote.fw-bold{
        font-size: 12px;
    }

#pr-testing .pr-hero__container .pink-bg h1 {
    font-size: 25px;
}
#pr-testing{
    margin-right: -5px;
}
/*Desktop */
@media (min-width: 992px) {
   
  .desktop-view-only {
    display: block;
  }
#pr-moa p.footnote.fw-bold {
    font-size: 10px;
    line-height: 12px;
}
    #pr-dosing .pr-hero__container .pink-bg h1 sup{
         font-size: 16px;   
    }
  .mobile-view-only {
    display: none;
  }
   #pr-testing{
    margin-right: 0;
}

  .cta-button.mobile-view-only {
    display: none;
  }

  .cta-button.desktop-view-only {
    display: block;
  }

  .desktop {
    display: inline-block;
  }

  .mobile {
    display: none;
  }

  .nccn-mobile-only {
    display: none;
  }

  .nccn-desktop-only {
    display: block;
  }
     
#pr-safety-combination-therapy .propel-content .cta-margin {
    margin-top: 40px;
}
  #testing-inner .flex-container.desktop-view-only {
    display: flex;
    flex-direction: row;
    align-items: center;
  }

  #testing-inner .flex-container.mobile-view-only {
    display: none;
  }

  #pr-moa .desktop.img-responsive-desktop1 {
    width: 100%;
  }
  #pr-moa .pr-hero__container .pink-bg h1{
      font-size: 30px;
    line-height: 36px;
  }
  #pr-moa .pr-hero__container .pink-bg{
          padding-top: 67px;
    padding-bottom: 50px;
  }

  #headTable h2 {
    font-size: 25px;
    line-height: 30px;
    padding-right: 170px;
    margin-top: 36px;
  }
  #pr-safety-combination-therapy .pr-hero__container .pink-bg {
          padding: 51px 0 39px;
  }
 #pr-safety-monotherapy .pr-hero__container .pink-bg{
     padding: 54px 0 67px;
 }
  #inner-content {
    max-width: 1024px;
    padding: 0 10px;
  }

  #headTable .neww-table {
    margin: 16px auto 35px auto;
  }

  #headTable .safety-study-section .safety-legend ul {
    margin-right: 0;
  }

  #headTable .safety-study-section .safety-legend ul li {
    margin-bottom: 0;
    font-size: 16px;
    margin-left: 16px;
    margin-top: 1px;
  }

  #headTable .neww-table th {
    font-size: 17px;
    line-height: 27px;
    letter-spacing: 0;
  }

  #headTable .neww-table td {
    font-weight: 400;
    font-size: 17px;
    line-height: 23px;
    color: #2B2E34;
    font-family: "roboto", sans-serif;
  }

  #headTable .val {
    font-size: 16px;
  }

  #headTable .safety-bar-table .reaction-name.pad-40 {
    padding-left: 40px;
  }

  #headTable .neww-table .reaction-name {
    font-size: 16px;
    line-height: 27px;
  }

  #inner-content .footnote.footnote-color {
    font-size: 10px;
    line-height: 12px;
  }

  .propel-content .cta-margin .cta-button {
    justify-content: flex-end;
  }

  #inner-content .sf-tbl-two .neww-table {
    margin-bottom: 0;
  }

  #inner-content .tbl-section-two .footnotecontiner.container-center {
    margin-top: 5px;
  }

  .propel-content .cta-margin {
    margin-top: 40px;
  }
.propel-content-testing .container-center {
     padding-left: 0; 
    padding-right: 10px;
}
  #headTable .neww-table td {
    font-size: 17px;
    line-height: 23px;
  }

  #headTable .neww-table td, #headTable .neww-table th {
    padding: 5px 8px;
  }

  #headTable .neww-table tr th:first-child, #headTable .neww-table tr td:first-child {
    padding-left: 20px;
  }

  #headTable .safety-bar-table .neww-table ul.chart li {
    margin: 5px auto;
  }

  #headTable .sf-tbl-two .safety-bar-table .neww-table ul.chart li {
    margin: 5px auto;
  }

  #inner-content .container-center.safetylistsect {
    margin-top: 25px;
    margin-bottom: 34px;
  }

  #inner-content .container-center.safetylistsect ul {
    font-size: 16px;
    padding-right: 4px;
  }

  #inner-content .container-center.safetylistsect ul li {
    margin-top: 2px;
    margin-bottom: 2px;
    line-height: 20px;
  }

  #inner-content .safetylistsect ul li:before {
    content: "•";
    font-size: 24px;
    position: relative;
    left: -5px;
    bottom: -4px;
  }

#pr-safety-monotherapy  #inner-content .container-center.safetylistsect ul li:nth-of-type(3) {
    margin-top: 2px;
  }

  #inner-content .footnote.footnote-color {
    margin-bottom: 0;
  }

  #inner-content .heading.blue-color.ff-roboto-bold {
    font-size: 25px;
    line-height: 28px;
  }

  #inner-content .footnotecontiner.container-center {
    padding-left: 5px;
  }

  #inner-content .container-center.safetylistsect {
    padding-left: 8px;
            padding-right: 6px;
  }
#inner-content .container-center.safetylistsect ul li:nth-of-type(3) {
     margin-top: 0; 
}
  #inner-content .dose-modification-safety-update table tr td {
    padding: 12px 0 14px 12px;
  }

  #inner-content .dose-modification-safety-update table tr td:first-child {
    font-size: 16px;
    line-height: 20px;
    padding-right: 0;
  }

  #inner-content .dose-modification-safety-update table tr:first-child td:last-child {
    font-size: 16px;
    padding: 3px 26px 5px;
    line-height: 20px;
  }

  #inner-content .dose-modification-safety-update table tr td.green-shade-bg {
    padding: 12px 26px 14px;
    font-size: 17px;
    line-height: 20px;
  }

  #inner-content .dose-modification-safety-update table tr td:first-child {
    padding-left: 12px;
  }

  #inner-content .dose-modification-safety-update table tr:first-child td:last-child {
    font-size: 16px;
    padding: 3px 26px 5px;
    line-height: 20px;
  }

  #inner-content .dose-modification-safety-update>div:last-child>p {
    font-size: 20px;
    line-height: 28px;
    padding: 10px 75px;
    transform: skewX(10deg);
  }

  #inner-content .dose-modification-safety-update>div:last-child {
    margin-left: 45px;
    transform: skewX(-10deg);
    margin-bottom: 0;
    text-align: center;
  }

  #headTable #sfTableTwo h2 {
    margin-top: 32px;
  }

  #headTable .neww-table td ul {
    display: flex;
    flex-direction: column;
    gap: 0;
  }

/*combination therapy end */
/*Monotherapy start */
#pr-safety-monotherapy #inner-content .monotherapy-footnote {
    font-size: 10px;
    line-height: 12px;
}
  #pr-safety-monotherapy #inner-content .dose-modification-safety-update table tr:first-child td:first-child {
    padding-bottom: 14px;
    padding-top: 12px;
  }

  #pr-safety-monotherapy #inner-content .dose-modification-safety-update table tr td:first-child {
    padding-right: 0;
  }

  #pr-safety-monotherapy .neww-table {
    margin-bottom: 0px;
  }

  #inner-content .monotherapy-footnote {
    font-size: 10px;
    line-height: 12px;
    color: #333333;
  }

  #headTable #sfTableTwo h2 {
    padding-right: 0;
  }

  #pr-safety-monotherapy #inner-content .dose-modification-safety-update table+p {
    font-size: 15px;
  }

  #pr-safety-monotherapy .safety-legend ul li {
    flex-direction: row;
  }

  #pr-safety-monotherapy .safety-legend ul li span {
    margin-right: 8px;
    margin-left: 0;
  }

  #pr-safety-monotherapy #inner-content .container-center {
    padding-left: 10px;
  }

  #pr-safety-monotherapy #inner-content .container-center.safetylistsect {
    padding-left: 14px;
  }

  #pr-safety-monotherapy #headTable #sfTableTwo h2 {
    margin-top: 35px;
  }

  #pr-safety-monotherapy .monotherapy-footnote.mar-top {
    margin-bottom: 0;
  }

  #pr-safety-monotherapy .propel-content .cta-margin {
    left: -4px;
  }
 #pr-safety-monotherapy #inner-content .footnotecontiner.container-center {
    margin-top: 5px;
}

/*Mechanism of action */
  #pr-moa .moa-combi .sect-1 .heading-1 {
    margin-bottom: 35px;
  }

  #pr-moa .heading-1 h2 {
    font-size: 25px;
    line-height: 28px;
    margin: 0;
  }

  #pr-moa .moa-combi .sect-1 .end-notes {
    margin-bottom: 35px;
  }

  #pr-moa .end-notes .footnotes {
    font-size: 10px;
    line-height: 12px;
  }

  #pr-moa .moa-combi .end-notes, .moa-mono p.footnote:nth-child(2) {
    padding-left: 8px;
  }

  #pr-moa .sect-1 .img-cont {
        margin-bottom: 0;
    margin-left: 0px;
    text-align: center;
    margin-right: -9px;
  }

  #pr-moa .footnote.note-text {
    font-size: 10px;
    line-height: 12px;
  }

  #pr-moa p.footnote.subnote-text {
    font-size: 12px;
    line-height: 14px;
  }

/*NCCN Guidelines*/
  .nccn-table-sec {
    margin: 36px auto;
  }

  .nccn-table-head {
    padding-bottom: 10px;
  }

  .nccn-table-sec .text-center {
    text-align: center;
  }

  .nccn-table-sec td {
    border-right: 1px solid #004D74;
    border-left: none;
  }

  .nccn-table-sec  tr:nth-child(3) td {
    height: 117px;
  }

  td.nccn-table-body p {
    margin: 13px 13.5px 0px 6px;
    min-width: 280px;
    width: 100%;
    max-width: 280px;
    font-size: 16px;
    line-height: 20px;
    letter-spacing: -0.48px;
  }

  .nccn-table-sec .nccn-body-cell {
    margin: 0 auto;
    width: fit-content;
    padding: 0 6px;
  }

  .nccn-table-sec tr:nth-child(4) {
    border-bottom: 30px solid #FFFFFF;
  }

  .nccn-table-sec  tr:nth-child(6) td:nth-child(2), .nccn-table-sec tr:nth-child(6) td:nth-child(3) {
    height: 134px;
  }

  .nccn-table-sec .nccn-body-cell span:nth-child(2) {
    display: block;
    margin: 0;
  }

  .nccn-table-sec tr:nth-child(7) td:nth-child(3) p {
    margin-bottom: 19px;
  }

  .nccn-table-sec tr:nth-child(7) td:nth-child(3) p {
    margin-bottom: 19px;
  }

  .nccn-table-sec .nccn-table-head {
    font-size: 25px;
    line-height: 28px;
    padding-bottom: 0;
  }

  #pr-nccn-guidelines .nccn-table-inner-head {
    padding-right: 0;
  }

  .nccn-table-sec tr:nth-child(5) td {
    border-right: 1px solid #004D74;
  }
  .nccn-table-sec .text-center {
    padding-bottom: 10px;
}
#pr-nccn-guidelines .nccn-table-sec tr:last-child td:nth-child(2) p, #pr-nccn-guidelines .nccn-table-sec tr:last-child td:nth-child(4) p {
        width: unset;
    }

#pr-nccn-guidelines .pr-hero__container .pink-bg {
        padding: 40px 0;
    }
#pr-nccn-guidelines .pr-hero__container .pink-bg h1{
        font-size: 30px;
    line-height: 36px;
    }

/*Hypothetical Patient Cases*/
  #pr-patient-profiles .patient-image img {
    width: 100%;
    max-width: 475px;
  }
#pr-patient-profiles .patient-heading {
    font-size: 24px;
}
  #pr-patient-profiles .flex-box.patient .box-2 {
    padding-top: 0;
    padding-right: 15px;
  }

  #pr-patient-profiles .flex-box.patient .box-2 {
    max-width: 466px;
    padding-left: 33px;
  }

  #pr-patient-profiles #pr-patient-profiles .patient-details .flex-box.patient {
    display: flex;
    flex-direction: row;
    column-gap: 54px;
  }

  #pr-patient-profiles .pr-combination-therapy, #pr-patient-profiles .pr-monotherapy {
    max-width: 1005px;
  }

  #pr-patient-profiles .flex-box.patient {
    flex-direction: row;
  }

  #pr-patient-profiles .skew-desc {
    max-width: 475px;
    margin: 26px auto 36px;
  }

  #pr-patient-profiles .skew-desc {
    transform: skewX(-10deg);
  }

  #pr-patient-profiles .skew-desc p {
    transform: skewX(10deg);
  }

  #pr-patient-profiles .pr-combination-therapy .flex-box.patient .box-2 {
    padding-top: 40px;
    padding-right: 0;
  }

  #pr-patient-profiles .section-head p {
    padding: 22px 0 20px;
  }

  #pr-patient-profiles .flex-box.patient .box>* {
    padding-left: 0;
    padding-right: 0;
  }

  #pr-patient-profiles .cta-button.desktop-view-only {
    text-align: center;
    display: inline-block;
  }

  #pr-patient-profiles .pr-monotherapy .patient-heading {
    font-size: 24px;
  }

  #pr-patient-profiles .pr-monotherapy .flex-box.patient .box-2 {
    max-width: 475px;
    width: 100%;
    padding-left: 0;
  }

  #pr-patient-profiles .pr-monotherapy .flex-box.patient .box-2 {
    padding-right: 0;
  }

  #pr-patient-profiles .pr-monotherapy .patient-details-list:has(.pink-ball) {
    padding-left: 33px;
    padding-right: 15px;
  }

  #pr-patient-profiles .pr-monotherapy .skew-desc {
    margin: 42px auto 36px;
  }

  #pr-patient-profiles .pr-monotherapy .patient-details-list ul li ul.patient-details-sublist {
    padding-left: 39px;
  }
  #pr-main-container .cta-button {
    justify-content: flex-end;
  }
  #pr-patient-profiles #pr-main-container  .cta-button {
    justify-content: center;
  }
  #pr-main-container .cta-button.mobile-view-only {
      display:none;
  }
 #pr-main-container .cta-button.desktop-view-only {
    display: block;
}
  #pr-safety-monotherapy .pr-hero__container .pink-bg h1 {
        font-size: 30px;
    line-height: 33px;
}
#pr-testing .pr-hero__container .pink-bg h1 {
    font-size: 30px;
}

}