#prostate-cancer-nav #mob-carousel {
    background-color: #990064;
}

.ff-roboto-reg {
      font-family: "roboto", sans-serif;
      font-weight: 400;
}
#pr-efficacy-combination-therapy #section-3 .skew-maroon-head {
        width: 96%;
    padding-left: 20px;
        margin-top: 45px;
}
#pr-efficacy-monotherapy #section-8-inner .list-section.secondary-endpoints-list .list-item {
        font-size: 16px;
    line-height: 22.8571px;
}
#pr-efficacy-monotherapy #section-8-inner .list-section.secondary-endpoints-list .list-item .list-bullet {
    margin-left: -6px;
    margin-right: -4px;
}
#pr-efficacy-monotherapy #section-4-inner .graph-data {
    padding: 10px 16px 20px 15px;
}
#pr-efficacy-monotherapy #section-4-inner .list-section .list-item {
    padding-left: 10px;
}
#pr-efficacy-monotherapy #section-5-inner.monotherapy-heading {
    margin-top: 20px;
}
#pr-home .combination-container .comb-ref-links .comb-links {
    flex-direction: column;
    text-align: center;
        gap: 11px;
    justify-content: center;
    align-items: center;
    padding: 14px 0 24px;
}
.ff-normal-400n {
    font-weight: 400;
}
.section-3.flex-box .card .card-content .flex-content .content p:nth-child(4){
    letter-spacing: -0.8px;
}
.section-3.flex-box .card .card-content .flex-content .content p:nth-child(5){
    padding-top: 7px;
    letter-spacing: -0.8px;
}
       #prostate-cancer-nav #global-nav-desktop .cmp-navigation__group .cmp-navigation__dropdownmenu .cmp-navigation__item--level-1 .cmp-navigation__item-link {
       padding: 10px 15px; 
    }
#pr-home #pr-home-references,
#pr-efficacy-combination-therapy #pr-efficacy-combination-therapy-references,
#pr-efficacy-monotherapy #pr-efficacy-monotherapy-references,
#pr-dosing #pr-dosing-references,
#pr-testing #pr-testing-references,
#pr-moa #pr-moa-references,
#pr-safety-combination-therapy #pr-safety-combination-therapy-references,
#pr-safety-monotherapy #pr-safety-monotherapy-references,
#pr-patient-profiles #pr-patient-profiles-references ,
#pr-nccn-guidelines #pr-nccn-guidelines-references{
    display: block;
}
#pr-patient-profiles:has(#patient-profiles-tabs-item-a26885cdb5-tab.cmp-tabs__tab--active)
 #pr-patient-profiles-references .mono-foots{
    display: none;
}

#pr-patient-profiles:has(#patient-profiles-tabs-item-08e0bc4a44-tab.cmp-tabs__tab--active)
 #pr-patient-profiles-references .combi-foots {
    display: none;
}



#pr-home #lynparzahcp-footer-container-2 #footer-pr-home, 
#pr-efficacy-combination-therapy #lynparzahcp-footer-container-2 #footer-pr-efficacy-combination-therapy,
#pr-efficacy-monotherapy #lynparzahcp-footer-container-2 #footer-pr-efficacy-monotherapy,
#pr-dosing #lynparzahcp-footer-container-2 #footer-pr-dosing,
#pr-testing #lynparzahcp-footer-container-2 #footer-pr-testing, 
#pr-moa #lynparzahcp-footer-container-2 #footer-pr-moa, 
#pr-safety-combination-therapy #lynparzahcp-footer-container-2 #footer-pr-safety-combination-therapy,
#pr-safety-monotherapy #lynparzahcp-footer-container-2 #footer-pr-safety-monotherapy,
#pr-patient-profiles #lynparzahcp-footer-container-2 #footer-pr-patient-profiles,
#pr-nccn-guidelines #lynparzahcp-footer-container-2 #footer-pr-nccn-guidelines,
#pr-resource-library #lynparzahcp-footer-container-2 #footer-pr-resource-library {
    display: block;
}
#prostate-cancer-nav .carousel-body a, #prostate-cancer-nav  .carousel-body .carousel-mob-sub-menu {
    color: #ffffff;
}
#prostate-cancer-nav .carousel-mob-sub-menu.active::after {
      background-color: #ffffff;
    width: calc(100% - 20px);
    height: 3px;
    left: 10px;
    display: inline-block;
    position: absolute;
    bottom: 6px;
    border-radius: 10px;
    content: "";
}

#prostate-cancer-nav  .carousel-body ul li.carousel-mob-sub-menu.show-subnav ul.sub-nav.has-select-txt li:nth-last-child(2) {
    border: none;
}
#prostate-cancer-nav .carousel-body .carousel-mob-sub-menu.dropdown-icon {
    padding-right: 8px;
}
#prostate-cancer-nav #mob-carousel .carousel-mob-sub-menu.show-subnav {
    background-color: #990064;
}
#prostate-cancer-nav #mob-carousel .carousel-mob-sub-menu.show-subnav .sub-nav {
     background-color: #990064;
}
#prostate-cancer-nav  .carousel-body ul>li>ul li {
    border-bottom: 2px solid #ffffff;
    border-right: none;
    padding: 20px 0;
}
#prostate-cancer-nav .dropdown-icon-span::after {
    background-image: url(/content/dam/intelligentcontent/brands/lynparzahcp-ic/us/en/images/global/header-dropdown-white.svg);
    position: relative;
    width: 12px;
    height: 18px;
}
#prostate-cancer-nav  .carousel-body li {
    padding: 10px 10px 11px;
    border-right: 1px solid #ffffff;
}
#pr-main-container{
    padding-top: 19px;
}
#pr-home #pr-main-container .cta-button{
    justify-content: flex-start;
    background: transparent;
}
#pr-home #pr-main-container {
    padding-top: 12px;
}

.parpi-image img,.celeb-10y img{
    width: 100%;
}
.banner-section-2 {
    padding: 20px 40px 9px 20px;
}
.pr-hero__container .pink-bg{
    padding: 20px 26px 20px 8px;
    text-align: left;
    color: #FFFFFF;
    font-family: "roboto", sans-serif;
      font-weight: 700;
    background-color: #990064;
}
.pr-hero__container .pink-bg h1{
    max-width: 1004px;
    margin: 0 auto;
    font-size: 24px;
    line-height: 30px;
    font-style: italic;
    font-weight: 700;
}
.pr-hero__container .pink-bg .pad-left.ittp-font {
        font-size: 20px;
    line-height: 26px;
    }
.pr-hero__container  .pink-bg  h1 span {
    margin-left: -2px;
}
.cmp-text .graph-data{
        width: 100%;
                padding: 10px 16px 20px 15px;
}
.fs-normal {
    font-style: normal;
}
.superscript-gap {
    margin-left: 2px;
}
#pr-efficacy-monotherapy #section-2-inner .image,
#pr-efficacy-monotherapy #section-3-inner .image,
#pr-efficacy-monotherapy #section-4-inner .image,
#pr-efficacy-monotherapy #section-5-inner .image,
#pr-efficacy-monotherapy #section-6-inner .image,
#pr-efficacy-monotherapy #section-7-inner .image{
    padding: 0 18px;
    margin: 20px 20px 0 18px;
}
#pr-main-container sup{
    font-size: .65em;
    top: -.5em;
    line-height: 0;
    position: relative;
    vertical-align: baseline;
}
#Reference-list .prostate-cancer-indication  .oc-home-footnote {
    margin-bottom: 40px;
}
#Reference-list .prostate-cancer-indication .footnote,.prostate-cancer-indication  .reference {
    font-size: 16px;
    line-height: 20px;
    font-family: "roboto", sans-serif;
      font-weight: 400;
}
#pr-efficacy-monotherapy #section-6-inner .graph-data{
        padding: 10px 16px 10px 15px;
}
#pr-efficacy-monotherapy #section-6-inner .list-section.last-para{
        margin: 20px 0;
}
#pr-efficacy-monotherapy #section-6-inner .list-section .list-item {
  padding-left: 10px;  
}
#pr-efficacy-monotherapy #section-6-inner .list-item .list-bullet {
        margin-left: -6px;
    margin-right: 0;
}

.prostate-cancer-indication .reference{
    margin-bottom: 45px;
    }
 
.pink-bg {
    background-color: #990064;
}
.home-combination  {
    max-width: 1366px;
    margin: 0 auto;
    margin-top: 7px;
    background-repeat: no-repeat;
    background-position-y: bottom;
}
.home-combination .combination-container{
    max-width: 1010px;
    margin: 0 auto;
}

    .home-combination .combination-container .section-1 {
    max-width: 724PX;
    margin: 0 0 0 auto;
       padding-top: 94px;
}
.home-combination .combination-container .section-1 .section-subhead {
    font-size: 18px;
    line-height: 24px;
    max-width: 630PX;
}
.ff-medium-500n {
    font-weight: 500;
}
.roboto-new-ff {
    font-family: "roboto", sans-serif;
}
.skew-maroon-head .pros-update-lime-clr-text {
    color: #B2D234;
}
    .ff-900n {
    font-weight: 900;
}
.mbottom_5 {
    margin-bottom: 5px;
}
 .graph-data p, .graph-data li {
    font-size: 16px;
    line-height: 20px;
    color: #333333;
}
        .desk-ot {
        display: none;
    }
        .mob-ot {
        display: block;
            white-space: nowrap;
    }
    .combination-container .section-heading i {
        font: normal normal 900 22px / 27px Roboto;
    }
    .pros-update-lime-clr-text {
        color: #E3C8D7;
    }
    .home-combination .not-actual-text {
        width: fit-content;
        margin-left: auto;
        font-size: 16px;
    line-height: 16px;
    }
        .flex-box.section-2 {
        display: flex;
        justify-content: space-between;
    }
    .flex-box.section-2 .box-1 {
    max-width: 696px;
    width: 100%;
}

   .ff-bold-700n {
    font-weight: 700;
}
.midd-pc{
        font-size: 16px;
    line-height: 22px;
}
.hgf-txt{
    font-size: 16px;
    line-height: 22.8571px;
}
.section-3.flex-box .card .card-content .flex-content .percentage {
    max-width: 98px;
    width: 100%;
}
.section-3.flex-box .card .card-content .flex-content .percentage p {
    font-size: 60px;
    line-height: 60px;
    letter-spacing: -3.84px;
}
#pr-efficacy-combination-therapy #section-2{
    padding-top: 4px;
}
.pink-color {
    color: #990064;
}
#pr-efficacy-monotherapy  #section-8-inner .list-section .list-item {
    font-family: "roboto", sans-serif;
      font-weight: 400;
    padding-left: 10px;
    line-height: 17.1429px;
    font-size: 12px;
}

.section-3.flex-box .card .card-content .flex-content .content p{
    font-size: 20px;
    margin-bottom: 3px;
    line-height: 24px;
}
.section-3.flex-box .card .card-content .flex-content .content p:nth-child(2n), .section-3.flex-box .card .card-content .flex-content .content p:nth-child(5) {
    font-size: 16px;
    line-height: 19px;
}
.padd-bot15 {
        padding-bottom: 15px;
    }
.ef-below-gragh-block .last-note {
    font-size: 10px;
    line-height: 12px;
}
#pr-home .card-link a {
    display: inline-block;
    max-width: 257px;
    width: 100%;
    text-align: center;
    border-radius: 7px;
    border: 2px solid #990064;
    font-family: "roboto", sans-serif;
      font-weight: 700;
    padding: 12.5px 0;
        font-size: 16px;
    line-height: 22.8571px;
}
#pr-home .card-link a:hover {
    background-color: #990064;
    color: white;
    text-decoration: underline;
}
#pr-home .nccn-section .nccn-container .card-link a:hover {
    background-color: #004D74;
    color: white;
}
#pr-home  .card-link a:after {
    content: "";
    display: inline-block;
    background-image: url(/content/dam/intelligentcontent/brands/lynparzahcp-ic/us/en/images/prostate-cancer/global/right-arrow-pink.png);
    width: 12px;
    height: 12px;
    background-size: cover;
    background-repeat: no-repeat;
    vertical-align: middle;
    margin-left: 9px;
}
#pr-home  .card-link  a:hover:after {
    background-image: url(/content/dam/intelligentcontent/brands/lynparzahcp-ic/us/en/images/right-arrow-white.png) !important;
}
.section-3.flex-box {
    display: flex;
    justify-content: space-between;
}
.section-3.flex-box .card {
    display: flex;
    flex-direction: column;
    justify-content: space-between;
}
.section-3.flex-box .card .card-content>p.newly-added-header {
    position: relative;
    font-size: 20px;
    line-height: 24px;
    top: 3px;
}
.section-3.flex-box .card .card-content>p {
    font-size: 18px;
    line-height: 24px;
}
.section-3.flex-box .card .card-content .flex-content {
    display: flex;
    justify-content: space-between;
    gap: 9px;
}
.text-underline {
    text-decoration: underline;
}
.pros-footnote {
    font-size: 13px;
    line-height: 16px;
}
.combination-container .comb-ref-links .comb-links {
    list-style: none;
    display: flex;
    margin-bottom: 10px;
}
.combination-container .comb-ref-links .comb-links  li a{
    font-size: 13px;
    line-height: 16px;
    color: #000;
}
.section-3.flex-box .card {
    background: #FFFFFF;
}
.section-3.flex-box {
    display: flex;
    padding: 0 2.5px;
    justify-content: space-between;
}
#pc-home-references .text-break-home {
        word-break: break-all;
    }
.skew-maroon-head{
    margin-bottom: 8px;
    margin-top: 24px;
    margin-right: 30px;
    width: 91%;
    padding: 15px 16px;
    padding-right: 16px;
    padding-left: 25px;
    background-color: #990064;
    transform: skewX(170deg);
    margin-left: -20px;
}
.skew-maroon-head h2{
    margin: 0;
    padding-left: 20px;
    line-height: 20px;
    font-size: 16px;
    color: #ffffff;
    transform: skewX(10deg);
    font-family: "roboto", sans-serif;
      font-weight: 700;
}
.propel-content .heading p {
        margin: 0 0 16px 0;
        font-size: 25px;
        line-height: 26px;
        font-family: "roboto", sans-serif;
      font-weight: 700;
    }
      
   #pr-efficacy-combination-therapy #section-2-inner{
        padding: 0 20px  8px 20px;
         background: #F8FFF7;
    }
    .list-section .list-item {
        font-size: 10px;
     font-family: "roboto", sans-serif;
      font-weight: 400;
    line-height: 14.2857px;
    }
   
    .ef-below-gragh-block {
        margin-top: 25px;
    }
    .ef-below-gragh-block div {
    margin-bottom: 20px;
}
.ef-below-gragh-block .list-graph {
    padding-left: 17px;
        margin-bottom: 10px;
            font-size: 16px;
    line-height: 22.8571px;
    list-style: disc;
}
.ef-below-gragh-block p {
    font-family: "roboto", sans-serif;
      font-weight: 400;
    font-size: 16px;
    line-height: 20px;
}
#pr-main-container .cmp-text{
    padding:  0;
}
#home-mono {
background: transparent linear-gradient(89deg, #801852 0%, #54222E 100%) 0% 0% no-repeat padding-box;
}

#home-mono  .card-link>a {
    background-color: #F3E8EE;
    color: #074E72;
    border: 2px solid #004D74;
}
#home-mono  .card-link {
    margin: 40px 0 40px;
}
#home-mono  #home-monotherapy-image{
    display: none;
}
#home-mono  #home-monotherapy-content .card {
    text-align: center;
}
#home-mono  #home-monotherapy-content .card {
background: transparent;
    box-shadow: none;
        padding: 0;
    margin: 0;
        margin-bottom: 10px;
}
#home-mono .home-eyebrow-subhead{
    padding-top: 24px;
    padding-bottom: 7px;
    color: #fff;
    font-size: 20px;
    line-height: 24px;
}
    #home-mono {
        margin-top: -9px;
    }
    #home-mono .cust-dev-c.div-pp{
       color: #FFFFFF;
    font-size: 16px;
    line-height: 19px;
    opacity: 1;
    text-align: center;
    }
    #home-mono .secondary-link a{
            font-size: 16px;
    line-height: 22.8571px;
    color: #fff;
    }
    #home-mono #home-monotherapy-inner{
            padding: 23px 30px 34px 30px;
    }
    #home-mono #home-monotherapy-content .image{
        margin-left: -30px;
    margin-top: 0;
    max-width: 270px;
    height: auto;
    width: 250px;
    }
    .nccn-section .nccn-container {
    background-color: #E5EDF0;
    }
    .ff-roboto-bold {
    font-family: "roboto", sans-serif;
      font-weight: 700;
}
#pr-efficacy-monotherapy #pr-main-container .cta-button a:after {
    position: relative;
    left: 8px;
}
#pr-efficacy-monotherapy .cta-button .blue-color {
    color: #004D74;
    padding: 17px 19px;
    min-width: 268px;
    text-align: left;
}
#section-8-inner {
    margin: 24px 0;
    padding-top: 14px;
}
#section-8-inner .black-color {
    margin-bottom: 8px;
    font-size: 18px;
}
.nccn-section .nccn-container  p {
    margin: 0 0 10px;
}
.white-bg {
    background-color: white;
}
#pr-home .nccn-section .nccn-container .card-link a {
    min-width: 282px;
    width: 100%;
    border-color: #004D74;
}
#pr-home  .parpi-section .flex-box.parpi-img-section {
    display: flex;
    justify-content: space-between;
    margin-bottom: 13px;
}
#pr-home .pros-footnote {
    font-size: 13px;
    line-height: 16px;
}
#pr-home .ast-footnote {
    margin-left: -7px;
}
#pr-efficacy-monotherapy .cta-button .blue-color {
    color: #004D74;
    padding: 17px 19px;
    min-width: 268px;
    text-align: left;
}
.cta-button a.blue-color {
    border: 5px solid #004D74;
    background-color: #B5CCD8;
    color: #004D74;
}
#pr-home  .nccn-section .nccn-container .flex-box p.card-link a:after {
    background-image: url(/content/dam/intelligentcontent/brands/lynparzahcp-ic/us/en/images/prostate-cancer/global/right-arrow-blue.png);
}
.dose-modification-safety-update table tr td:first-child {
    padding-left: 12px;
    border-left: none;
}
.dose-modification-safety-update table tr:first-child td {
    border: none;
}
.dose-modification-safety-update table tr td:first-child {
    color: #333333;
}
.dose-modification-safety-update table tr td {
        font-size: 16px;
        line-height: 20px;
    }
 .dose-modification-safety-update table tr td {
    padding: 12px 0 14px 12px;
}
.dose-modification-safety-update table tr:first-child td:last-child {
    font-size: 16px;
}
 .dose-modification-safety-update table {
    max-width: 709px;
    margin: 0 auto;
    width: 100%;
}
 .dose-modification-safety-update table tr td {
    border: 1px solid #3E4444;
}
.dose-modification-safety-update table tr:first-child td:last-child {
    padding: 3px 26px 5px;
}
.dose-modification-safety-update table tr:first-child td:last-child {
    background-color: #B2D234;
}
.dose-modification-safety-update table tr td:last-child {
    text-align: center;
}
.dose-modification-safety-update table tr .green-shade-bg {
    background-color: #F7FAEA;
}
#pr-efficacy-combination-therapy .pink-bg {
        padding: 20px 22px 21px 18px;
    box-shadow: 0 5px 10px #99006484;
}
.pink-bg .max-width p {
            line-height: 24px;
    font-size: 20px;
    font-family: "roboto", sans-serif;
      font-weight: 700;
    }
    .pink-bg .max-width  h1 {
    font-size: 24px;
    line-height: 30px;
    margin-top: 8px;
    letter-spacing: 0.24px;
    font-family: "roboto", sans-serif;
      font-weight: 700;
}
.pink-bg .max-width .banner-heading sup {
    font-style: normal;
    margin-left: 5px;
}
 #pr-main-container #summary-bottom-section .image img {
    position: absolute;
    max-width: 292px;
    z-index: 9;
    top: -208px;
    width: 292px;
    left: -27px;
}
   #pr-main-container #summary-top-section {
        background: #F5E5EF;
    }
   #pr-main-container #summary-bottom-section,#pr-main-container .scroll-info-section {
        background: #990064;
    }
    #pr-main-container .scroll-content {
    color: #ffffff;
}
#pr-efficacy-monotherapy #summary-top-section #summary-top-section-content {
        max-width: 752px;
}

    #pr-main-container #summary-top-section #summary-top-section-img {
        width: 234px;
    }
   #pr-main-container #summary-section .not-actual-patient{
        position: absolute;
    bottom: 1px;
    font-size: 14px;
    line-height: 10px;
    text-shadow: none;
    color: #fff;
    top: 59px;
    left: 94px;
    font-weight: 700;
    }
   .banner-section-2 .flex-container {
    gap: 16px;
    display: flex;
    flex-direction: column;
}
    .banner-section-2 .flex-container .column .column-2.content p:last-child {
   font-family: "roboto", sans-serif;
      font-weight: 700;
    line-height: 17px;
    margin: 0px;
}
.banner-section-2 .flex-container .column>p,.banner-section-2 .flex-container .para-2 {
    font-size: 15px;
    line-height: 17px;
    margin: 0;
}
.banner-section-2 .flex-container .column-1.column .para-2,
.banner-section-2 .flex-container .column-2.column .content p:last-child{
      padding-right: 20px;
}
.ff-myriad {
    font-family: "myriad-pro", sans-serif;
}
.banner-section-2 .flex-container .flex-container {
    display: flex;
    margin-top: 4px;
    gap: 0;
    flex-direction: row;
}
.banner-section-2 .flex-container .percentage.column-1 p{
   font-family: "roboto", sans-serif;
      font-weight: 900;
    font-size: 65px;
    line-height: 55px;
    margin-left: -5px;
    margin-right: 8px;
    letter-spacing: -5.2px;
}
#pr-efficacy-monotherapy .banner-section-2 .flex-container .percentage.column-1 p{
        letter-spacing: -2.54px;
}
#pr-efficacy-monotherapy .banner-section-2 {
    padding: 20px 20px 9px 20px;
}
#pr-main-container .scroll-info-section .flex-container{
        padding: 15px 35px 12px 18px;
    flex-direction: column-reverse;
    align-items: center;
    gap: 8px;
    display: flex;
    max-width: 1014px;
    margin: 0 auto;
}
.mobile-only.image-content.clinical-endpoints-section p{
    font-size: 16px;
    line-height: 20px;
}

.primary-endpoint-content, .secondary-endpoints-list li{
    font-family: "roboto", sans-serif;
      font-weight: 400;
    color: #58595B;
}
.secondary-endpoint-heading{
        margin: 22px 0 11px;
    }
   .mobile-only.image-content.clinical-endpoints-section .mob-new-content.treatment-note{
        font-size: 20px;
    line-height: 24px;
    font-family: "roboto", sans-serif;
    color: #58595B;
    text-align: center;
    max-width: 948px;
    }
    .patient-eligibility-note{
     margin: 27px 0 9px;
    padding-right: 5px;
    line-height: 26px;
    font-size: 20px;
    text-align: center;   
    }
   
  #pr-efficacy-monotherapy  .list-section.secondary-endpoints-list .list-item.secondary-endpoint-item{
    padding-left: 10px;
}
 #pr-main-container .flex-container .column> .para-3 {
    margin-top: 9px;
}
.banner-section-2 .row-2 {
    font-size: 15px;
    line-height: 17px;
    margin-top: 6px;
    margin-bottom: 0;
}
#pr-main-container .banner-section-2 .flex-container .percentage.column-1 p sup{
    font-size: 32px;
    font-style: normal;
    top: -24px;
    margin-left: 12px;
}

.banner-section-2 .flex-container .column-2.content .pink-color{
    font-size: 16px;
    letter-spacing: -0.78px;
    line-height: 18px;
   font-family: "roboto", sans-serif;
      font-weight: 700;
}
.flex-container .column .column-2.content p:last-child {
    font-family: "roboto", sans-serif;
      font-weight: 700;
    line-height: 17px;
    margin-top: 0;
}
.banner-section-2 .flex-container .column .para-1 {
        padding-right: 17px;
    padding-left: 5px;
    font-weight: 700;
    }
     #pr-main-container.scroll-info-section .flex-container {
    padding: 15px 35px 12px 18px;
        flex-direction: column-reverse;
        align-items: center;
        gap: 8px;
        }
        .propel-examined {
     margin: 0 20px 0;
    align-items: center;
    gap: 16px;
    flex-direction: column;
    display: flex;
    padding: 40px 0 0;
    max-width: 1005px;
        }
        .propel-examined>p {
    font-size: 25px;
    line-height: 28px;
    max-width: 729px;
    font-family: "roboto", sans-serif;
      font-weight: 700;
}
#section-8-inner .monotherapy-heading {
    padding-right: 15px;
    font-size: 25px;
    line-height: 28px;
}
#propel-p3,#profound-p3{
    scroll-margin-top: 150px;
}
.propel-examined a.flex-container {
        flex-direction: row;
        max-width: 319px;
    padding: 15px 24px;
    border: 3px solid #990064;
    border-radius: 8px;
    background-color: #EEDAE7;
    text-align: center;
    gap: 16px;
    width: 100%;
    font-size: 16px;
    line-height: 20px;
    display: flex;
    font-family: "roboto", sans-serif;
      font-weight: 700;
    padding-left: 32px;
}
.propel-content .Primary_endpoint {
    margin: 4px auto 0;
    overflow: auto;
}
.propel-content .skew-maroon-head {
    width: 91%;
    margin: 24px 30px 8px -20px;
    padding: 15px 16px;
    background-color: #990064;
    box-shadow: none;
    transform: skewX(-10deg);
}
.skew-maroon-head .eff-comb-update {
        font-size: 16px;
    line-height: 20px;
    margin-bottom: 5px;
}
    .propel-link::after {
    content: "";
    display: inline-block;
    max-width: 17px;
    height: 40px;
    margin-left: 8px;
    background: url(/content/dam/intelligentcontent/brands/lynparzahcp-ic/us/en/images/prostate-cancer/global/downarrow-magenta.svg) no-repeat center;
    background-size: contain;
    transition: background-image 0.3s ease;
    vertical-align: middle;
    width: 100%;
}

.propel-examined a.flex-container.pink-color:hover {
    text-decoration: none;
    background: #990064;
    color: #ffffff;
}
.propel-link:hover::after {
    background-image: url('/content/dam/intelligentcontent/brands/lynparzahcp-ic/us/en/images/prostate-cancer/global/downarrow-white.svg');
}
#pr-efficacy-combination-therapy #section-3-inner {
    padding: 0 20px 8px 20px;
}
#pr-efficacy-combination-therapy #section-4{
        padding: 0 20px;
                margin-top: 4px;
}
#section-4 .skew-maroon-head {
    margin-left: 6px;
    max-width: 188px;
    padding: 10px 12px;
    margin-top: 4px;
    margin-bottom: 0;
}
.monotherapy-heading{
        margin-top: 13px;
    padding-left: 18px;
    padding-right: 20px;
    font-size: 20px;
    line-height: 25px;
}
#section-4 .skew-maroon-head h2 {
    padding: 0;
}
#section-4 .section-heading p{
    font-size: 20px;
    margin: 20px 0 23px;
    line-height: 28px;
}
 #section-4 .content {
        margin-top: 32px;
    }
    #section-4 .content  p{
        font-size: 14px;
    line-height: 20px;
    font-family: "roboto", sans-serif;
      font-weight: 400;
    }
     #section-4 .content p:nth-child(2) {
        margin: 19px 0 19px;
    }
     #section-4 .content ul {
        margin: 11px 0 24px;
    }
    #section-4 .content li {
        font-size: 12px;
    position: relative;
    padding-left: 10px;
    font-family: "roboto", sans-serif;
      font-weight: 400;
    line-height: 17.1429px;
    }
      #section-4 .content li sup,#section-4 .content li span {
        margin-left: -7px;
     }
    #pr-efficacy-monotherapy .pr-hero__container .pink-bg {
    padding: 20px 17px 20px 16px;
    box-shadow: 0 5px 10px #99006484;
}
#pr-efficacy-monotherapy .pink-bg h1 span {
     margin-left:0; 
}
#pr-efficacy-monotherapy .pink-bg .banner-heading {
    font-size: 24px;
    line-height: 30px;
    font-family: "roboto", sans-serif;
      font-weight: 700;
    margin-top: 8px;
    font-style: italic;
    letter-spacing: 0;
}
#pr-efficacy-monotherapy .pink-bg .banner-heading sup {
    font-style: normal;
    margin-left: 5px;
}
.graph-head{
        overflow: hidden;
    padding: 24px 0 0;
}
.graph-head .pink-bg.skew-10{
        margin-left: -15px;
    margin-right: 90px;
}
.graph-head .pink-bg.skew-10 h2{ 
    margin: 0;
    padding: 15px 29px;
    padding-left: 35px;
}
.graph-head .pink-bg.skew-10 h2 .side-heading{ 
    font-size: 13px;
    line-height: 20px;
}
.graph-head .pink-bg.skew-10 h2  p{
    font-size: 16px;
    line-height: 18px;
}
.efficacy-secondary-endpoint{
        max-width: 1005px;
    margin: 0 auto;
}
.efficacy-secondary-endpoint .cohort-a {
    margin: 16px 0 24px 20px;
    max-width: 87%;
    transform: skew(-5deg);
    border-left: 5px solid #990064;
    background-color: #EBDCE6;
    margin-top: 0;
}
.efficacy-secondary-endpoint .cohort-a>.skew10{
    transform: skew(5deg);
    padding: 8px 22px 6px 20px;
    max-width: 835px;
}
.efficacy-secondary-endpoint .cohort-a .card-head {
    font-size: 20px;
    line-height: 26px;
}
.efficacy-secondary-endpoint .cohort-a .card-content {
    font-size: 16px;
    line-height: 23px;
    font-family: "roboto", sans-serif;
      font-weight: 400;
}
.efficacy-secondary-endpoint .cohort-a .card-foot{
    font-size: 12px;
    line-height: 14px;
    font-family: "roboto", sans-serif;
      font-weight: 400;
}
#section-8-inner .image{
    margin: 5px 0 15px 0;
    padding: 0;
}
#section-8-inner .image img{
    max-width: 377px;
}
#section-8-inner .inner-content{
    padding: 0 14px 1px 18px;
    }
 #pr-efficacy-monotherapy   .propel-examined {
    padding: 0;
    gap: 34px;
    padding-top: 16px;
}
 #pr-efficacy-monotherapy  .propel-link::after {
    height: 20px;
}
 #pr-efficacy-monotherapy  .propel-examined a.flex-container {
        padding: 15px 0;
    max-width: 339px;
    justify-content: center;
    gap: 8px;
}
.graph-data .last-para {
    margin-top: 8px;
    font-family: "roboto", sans-serif;
      font-weight: 700;
}
.graph-head .pros-update-lime-clr-text {
    color: #B2D234;
}
 #pr-efficacy-monotherapy .list-item .list-bullet {
    margin-left: -6px;
    margin-right: 5px;
}
 #pr-efficacy-monotherapy .list-section  {
     margin-bottom: 10px;
 }
 #pr-efficacy-monotherapy #section-8-inner .list-section li:nth-child(1) {
    padding-bottom: 0;
}

 #pr-efficacy-monotherapy  #section-8-inner .list-section .list-item .list-bullet {
   margin-left: -6px;
       margin-right: 0;
}
#section-5-inner .graph-head .pink-bg.skew-10,
#section-6-inner .graph-head .pink-bg.skew-10{
    margin-right: 50px;
}
#section-6-inner .graph-head .pink-bg.skew-10 h2 {
    padding-right: 60px;
}
/* #pr-efficacy-monotherapy .list-section li:nth-child(1) {*/
/*    padding-bottom: 4px;*/
/*}*/
#section-4-inner .graph-head .pink-bg.skew-10 {
    margin-right: 30px;
}
#section-4-inner .graph-data .last-para {
    margin-top: 20px;
    padding: 8px 0;
}
#section-4-inner .graph-data {
        padding: 20px 16px 40px 15px;
}
    #pr-efficacy-monotherapy #section-3,
    #pr-efficacy-monotherapy #section-5,
    #pr-efficacy-monotherapy #section-8 {
        background-color: rgba(0, 77, 116, 0.05);
    }
 #pr-efficacy-monotherapy .list-section .list-item {
    font-family: "roboto", sans-serif;
      font-weight: 400;
    padding-left: 15px;
    font-size: 16px;
    line-height: 20px;
}
.fw-regular {
    font-weight: 400;
}
#pr-main-container #summary-section .scroll-icon img {
    max-width: 33.354px;
}
#pr-main-container .scroll-content .scroll-heading {
    font-family: 'myriad-pro', sans-serif;
    font-weight: 700;
    font-size: 18px;
    line-height: 18px;
}
#pr-main-container .scroll-content .scroll-description {
    font-weight: 700;
    font-family: 'myriad-pro', sans-serif;
    font-size: 18px;
    line-height: 18px;
}
#section-3 .monotherapy-heading {
    margin-top: 19px;
}
#pr-efficacy-monotherapy .cta-button .blue-color:hover {
        color: #fff;
}
#pr-home #home-mono .card-link a:after {
    background-image: url(/content/dam/intelligentcontent/brands/lynparzahcp-ic/us/en/images/prostate-cancer/global/right-arrow-blue.png);
}
    
    @media (max-width: 992px) {
        #pr-home .parpi-section {
        padding: 18px 20px 0;
    }
    #testing-inner .section-2 .section-2-content table tr td {
    padding-top: 19px;
}
    #testing-inner .section-2 .box.table-content ul li {
    padding-right: 10px;
}
   #pr-home .parpi-section .pros-footnote {
        padding-right: 20px;
    }
   #pr-home  .parpi-section .flex-box.parpi-img-section {
        flex-direction: column;
        gap: 12px;
    }
        .nccn-section .nccn-container .flex-box .pros-footnote {
        margin: 0;
        padding-right: 18px;
    }
        .nccn-section .nccn-container .flex-box {
        flex-direction: column;
        gap: 24px;
        display: flex;
                align-items: center;
    }
        .nccn-section .nccn-container>p:nth-child(2) {
        margin: 12px 0;
        padding-right: 10px;
        line-height: 22.8571px;
    }
        .nccn-section .nccn-container>p:first-child {
        font-size: 32px;
        line-height: 38px;
    }
        .home-combination .combination-container .section-1 .section-heading {
        margin-right: 0;
        margin-left: auto;
        width: fit-content;
        margin: 38px 0 0 184px;
        font-size: 22px;
        line-height: 27px;
        max-width: 172px;
    }
   
        .home-combination .combination-container .section-1 {
   padding: 20px 31px 0 17px;
}
       #pr-efficacy-combination-therapy .combination-container .comb-ref-links .comb-links {
        flex-direction: column;
        gap: 8px;
        justify-content: center;
        align-items: center;
        padding: 14px 0 22px;
    }
    
        .combination-container .comb-ref-links {
        padding: 10px 34px 0 20px;
    }
        .combination-container .comb-ref-links {
        margin: 0;
        background-color: #F5E6F0;
    }
        .section-3.flex-box .card .card-content .flex-content {
        margin-bottom: 40px;
    }
            .section-3.flex-box {
        flex-direction: column;
        padding: 0;
    }
        .section-3.flex-box .card .card-content>p.newly-added-header {
        margin-left: 103px;
    }
    .section-3.flex-box .card.card-1 {
        border-bottom: 8px solid #990064;
    }
    .section-3.flex-box .card {
        padding: 12px 25px 21px 14px;
    }
            .section-3.flex-box .card-link {
        text-align: center;
        margin-bottom: 26px;
    }
            .section-3.flex-box .card .card-content .flex-content .content .subhead {
        letter-spacing: -1.2px;
    }
        .section-3.flex-box .card .card-content .flex-content .content p {
        letter-spacing: -0.48px;
    }
        
    .flex-box.section-2 .box-2 {
        max-width: 100%;
        text-align: left;
        display: flex;
        flex-direction: row-reverse;
        gap: 20px;
        align-items: center;
        padding-top: 2px;
        padding-bottom: 5px;
    }
        .home-combination .not-actual-text {
        max-width: 172px;
        z-index: 2;
    margin: 30px 20px 5px auto;
    position: relative;
    top: -13px;
    }
    .home-eyebrow-subhead {
        font-size: 16px;
        line-height: 19px;
    }
    .section-2 .home-eyebrow-subhead {
        margin: 10px 0 14px;
    }
        .flex-box.section-2 {
        gap: 20px;
        max-width: calc(100%);
        position: relative;
        z-index: 1;
        align-items: flex-start;
        margin: 6px 0 0;
        flex-direction: column-reverse;
    }
        .flex-box.section-2>* {
        padding: 0 32px 0 20px;
    }
    .flex-box.section-2 .box-2 {
        background: transparent linear-gradient(90deg, #990064 0%, #54222E 100%) 0% 0% no-repeat padding-box;
    }
    .combination-container .mob-bg-gradient {
    background-size: cover;
    background-image: url(/content/dam/intelligentcontent/brands/lynparzahcp-ic/us/en/images/prostate-cancer/mobile/pat-mob-img.jpg);
}
.combination-container .mob-bg-gradient {
        background-position-y: top 28%;
    }
     .home-combination .combination-container .section-1 {
        padding-right: 17px;
        min-height: auto;
        padding-bottom: 44%;
    }
    .nccn-section .nccn-container {
        margin: 0;
        padding: 12px 18px 20px 18px;
    }
    }
    
    /*#patient-profiles.html#monotherapy*/
    
   #patient-profiles-tabs .cmp-tabs__tablist{
   background: #990064;
    padding: 20px 0 202px;
    display: flex;
    justify-content: center;
    margin: 0;
    list-style: none;
    gap: 0;
}

#patient-profiles-tabs .cmp-tabs__tablist li{
    background:#fff;
    flex:1 1 50%;
    max-width:248px;

    padding:10px 11px 15px;
    font-size:15px;
    line-height:18px;
    color:#990064;
    font-family: "roboto", sans-serif;
      font-weight: 700;

    text-align:center;
    box-sizing:border-box;
    background-color: #F3E8EE;
color: rgba(128, 24, 82, 0.35);
font-style: italic;
}
#patient-profiles-tabs .cmp-tabs__tablist .cmp-tabs__tab.cmp-tabs__tab--active{
    color:#990064;
    background:#fff;
}
.patient-profiles-heading{
    line-height: 40px;
    color: #fff;
    font-size: 30px;
    font-family: "roboto", sans-serif;
      font-weight: 700;
    font-style: italic;
    position: absolute;
        margin: 100px 34px 22px 20px;
    z-index: 10;
}
#patient-profiles-tabs{
    z-index: 9;
    position: relative;
}


/*isi*/
#Reference-list .prostate-cancer-indication #pr-home-references .oc-home-footnote{
    margin-bottom: 17px;
}
#pr-home-references .reference{
        margin-bottom: 34px;
        margin-left: -1px;
}
#pr-efficacy-monotherapy-references .footnote_end{
    margin-bottom: 40px;
}
    #pr-efficacy-combination-therapy .prostate-cancer-indication p.footnote {
    margin-bottom: 7px;
}
#pr-testing-references p,#pr-testing-references .reference-container{
    font-family: "roboto", sans-serif;
      font-weight: 400;
    font-size: 16px;
    line-height: 22.8571px;
}
#pr-testing-references  .reference-container{
        margin: 24px 0;
}
#pr-dosing-references .footnote_end {
        padding-top: 25px;
    margin-bottom: 20px;
}
#pr-dosing-references .refs.reference p{
    font-family: "roboto", sans-serif;
      font-weight: 400;
    font-size: 14px;
    line-height: 20px;
}
#pr-safety-combination-therapy-references .footnote{
    margin-bottom: 20px;
    color: #333333;
}
#pr-patient-profiles #Reference-list .prostate-cancer-indication  .footnote{
        margin-bottom: 20px;
   line-height: 20px;
}
#pr-moa-references .footnote,
#pr-nccn-guidelines-references .footnote{
    margin-bottom: 20px;
}
#pr-safety-combination-therapy .pr-hero__container .pink-bg {
    padding: 20px 26px 20px 18px;
}
    #pr-patient-profiles .section-head p sup{
            margin-left: 4px;
    }
    #pr-patient-profiles #pr-main-container .aem-Grid::after {
    clear: none;
}
@media only screen and (min-width: 992px) {
    #pr-efficacy-monotherapy #section-6-inner .image{
        padding: 20px 0 0;
    margin: 0;
    }
    #pr-efficacy-monotherapy #section-6-inner .graph-data {
       padding: 20px 0 40px; 
    }
     #pr-patient-profiles .box-2.box .patient-details-list ul li .patient-details-sublist {
    padding-left: 39px;
   }
    #pr-safety-combination-therapy .pr-hero__container .pink-bg h1 span {
    margin-left: -2px;
    font-size: 30px;
    line-height: 36px;
}
  #pr-home  #pr-main-container{
    padding-top: 36px;
}
    #pr-main-container {
        padding-top: 45px;
    }
    .desk-ot {
        display: inline-block;
    }
        .mob-ot {
        display: none;
            white-space: nowrap;
    }

     #lynparzahcp-header .cmp-navigation__group li:nth-child(1).has-selected .cmp-navigation__item-link.tumor-prostate-cancer{
        padding: 6px 17px 6px 14px;   
       }

#prostate-cancer-nav {
        position: fixed;
        width: 100%;
        z-index: 99;
    }
     #prostate-cancer-nav #global-nav-desktop {
    display:block;
}  
#prostate-cancer-nav #global-nav-desktop .cmp-navigation__group .cmp-navigation__item--level-0 .cmp-navigation__item-link {
    padding: 12px 4px 7px;
}
    #main-container-pc {
    padding-top: 44px;
    }
    #prostate-cancer-nav #global-nav-desktop .cmp-navigation {
        background-color: #990064;
        box-shadow: 0px 3px 6px #00000029;
        height: 45px;
    }

#prostate-cancer-nav #global-nav-desktop .cmp-navigation__dropdownmenu {
        background-color: #990064;
        border-radius: 0 0 10px 10px;
    }
  #prostate-cancer-nav   .cmp-navigation__group .cmp-navigation__item--level-0 .cmp-navigation__item-link {
        color: #ffffff;
    }
   #prostate-cancer-nav .cmp-navigation__item--level-0.active > .cmp-navigation__item-link,
#prostate-cancer-nav .cmp-navigation__item--level-0 > .cmp-navigation__item-link:hover,
#pr-resource-library #prostate-cancer-nav .cmp-navigation__item--level-0:last-child> .cmp-navigation__item-link{
    border-bottom: 5px solid #fff;
}
/*      #prostate-cancer-nav #global-nav-desktop .cmp-navigation__group > li:nth-child(2) > .cmp-navigation__item-link::after, */
/*  #prostate-cancer-nav #global-nav-desktop .cmp-navigation__group > li:nth-child(5) > .cmp-navigation__item-link::after,*/
/*   #prostate-cancer-nav #global-nav-desktop .cmp-navigation__group > li:nth-child(6) > .cmp-navigation__item-link::after,*/
/*   #prostate-cancer-nav #global-nav-desktop .cmp-navigation__group > li:nth-child(7) > .cmp-navigation__item-link::after {*/
/*        content: "\f0d7";*/
/*        font-family: fontawesome;*/
/*        vertical-align: middle;*/
/*        font-size: 18px;*/
/*        color: #ffffff;*/
/*    }*/
/*    #prostate-cancer-nav #global-nav-desktop .cmp-navigation__group > li:nth-child(2):hover  > .cmp-navigation__dropdownmenu,*/
/*    #prostate-cancer-nav #global-nav-desktop .cmp-navigation__group > li:nth-child(5):hover  > .cmp-navigation__dropdownmenu,*/
/*    #prostate-cancer-nav #global-nav-desktop .cmp-navigation__group > li:nth-child(6):hover  > .cmp-navigation__dropdownmenu,*/
/*    #prostate-cancer-nav #global-nav-desktop .cmp-navigation__group > li:nth-child(7):hover  > .cmp-navigation__dropdownmenu{*/
/*     display: block;*/
/*         min-width: 100%;*/
/*    }*/

/*#prostate-cancer-nav #global-nav-desktop .cmp-navigation__group > li:nth-child(2):hover > .cmp-navigation__item-link::after,*/
/*#prostate-cancer-nav #global-nav-desktop .cmp-navigation__group > li:nth-child(5):hover > .cmp-navigation__item-link::after,*/
/*#prostate-cancer-nav #global-nav-desktop .cmp-navigation__group > li:nth-child(6):hover > .cmp-navigation__item-link::after,*/
/*#prostate-cancer-nav #global-nav-desktop .cmp-navigation__group > li:nth-child(7):hover > .cmp-navigation__item-link::after {*/
/*    content: "\f0d8";*/
/*}*/
#prostate-cancer-nav #global-nav-desktop .cmp-navigation__group > li > .cmp-navigation__item-link::after,
#breast-cancer-nav #global-nav-desktop .cmp-navigation__group > li > .cmp-navigation__item-link::after{
background-image: url(/content/dam/intelligentcontent/brands/lynparzahcp-ic/us/en/images/global/header-dropdown-white.svg);
}
.pr-hero__container .pink-bg {
    padding: 51px 0 39px;
}
.pink-bg .pad-left.ittp-font {
    line-height: 22px;
}
.pr-hero__container .pink-bg h1 { 
   font-size: 30px;
    line-height: 36px; 
}
.home-combination {
        background-image: url(/content/dam/intelligentcontent/brands/lynparzahcp-ic/us/en/images/prostate-cancer/desktop/patient-img-desktop.jpg);
        background-size: cover;
        background-repeat: no-repeat;
        max-width: 100%;
    }
         .home-combination {
        background-position-y: top;
    }
    .home-combination .combination-container .section-1 .section-heading {
    margin: 0;
    font-size: 34px;
    line-height: 44px;
}
.section-3.flex-box .card {
        border: 1px solid #004D74;
    }
    .home-combination .not-actual-text {
        letter-spacing: .3px;
        margin-left: 0;
    }
       .flex-box.section-2 {
        margin: 11px 0;
    }
    .flex-box.section-2 .home-eyebrow-subhead{
        padding-top: 6px;
    }
    .hgf-txt {
        line-height: 19px;
    }
    .flex-box.section-2 .box-2 img{
            position: relative;
    bottom: 10px;
    }
    .flex-box.section-2 .box-1 {
    max-width: 696px;
    width: 100%;
}
    .flex-box.section-2 .box-2 {
        display: flex;
        align-items: center;
        flex-direction: column-reverse;
    }
    .midd-pc {
        font-size: 20px;
    line-height: 24px;
    }
    .flex-box.section-2 .box-2 {
    max-width: 266px;
    width: 100%;
    text-align: center;
}
.section-3.flex-box .card {
    max-width: 490px;
    width: 100%;
    display: flex;
    flex-direction: column;
    justify-content: space-between;
    padding: 14px 18px 21px 17px;
}
.section-3.flex-box .card .card-content>p.newly-added-header {
    margin-left: 108px;
}
.section-3.flex-box .card-link {
    text-align: right;
}
.combination-container .comb-ref-links {
        margin: 10px 0 0;
        color: #FFFFFF;
        max-width: 607px;
    }
    .pros-footnote {
    font-size: 13px;
    line-height: 16px;
}
.combination-container .comb-ref-links .comb-links li a {
    font-size: 16px;
    line-height: 22.8571px;
    color: #ffffff;
}
#home-mono {
        margin-top: -11px;
    }
   #home-mono .home-eyebrow-subhead {
    margin-bottom: 7px;
    font-size: 20px;
    line-height: 24px;
    color: #004D74;
    padding: 0;
}
#home-mono .cust-dev-c.div-pp {
        color: #004D74;
    }
    .combination-container .section-heading i {
    font: normal normal 900 34px / 44px Roboto;
}
.home-combination .combination-container .section-1 .section-subhead {
    margin-top: 10px;
    margin-bottom: 26px;
}
#home-mono #home-monotherapy-image {
    display: block;
    margin-left: 40px;
}
  #pr-home  #home-monotherapy-inner .not-real-patients p {
            padding: 0;
    left: 0px;
    letter-spacing: .3px;
    font-family: "roboto", sans-serif;
    }
#home-mono #home-monotherapy-content .card {
           background: white;
        box-shadow: 0px 0px 16px rgba(0, 0, 0, 0.7);
        padding: 15px 26px;
        width: 100%;
    margin-top: 10px;
    padding-bottom: 16px;
    margin-bottom: 5px;
}
#home-mono {
    border-top: 6px solid #990064;
    border-bottom: 6px solid #990064;
    background: transparent linear-gradient(90deg, #54222E 0%, #801852 28%, #801852 77%, #54222E 100%) 0% 0% no-repeat;
}
#pr-main-container .nccn-section {
           max-width: 1004px;
    margin: 0 auto;
    padding-top: 0;
}
#home-mono #home-monotherapy-inner {
    padding: 0;
    margin-top: 22px;
    max-width: 1010px;
    justify-content: flex-start;
}
#home-mono #home-monotherapy-content .image {
    margin-left: 0;
    margin-bottom: 0;
}
#pr-main-container  #home-monotherapy-content{
        padding-top: 15px;
}
#home-mono .card-link {
    margin: 13px 0 22px;
}
#home-mono .secondary-link a {
        color: #004D74;
}
.nccn-section .nccn-container {
    margin: 24px 0;
    padding: 12px 18px 12px 15px;
}
.nccn-section .nccn-container>p:first-child {
    font-size: 32px;
    line-height: 50px;
}
.nccn-section .nccn-container>p:nth-child(2) {
    margin: 10px 0 12px;
        line-height: 22.8571px;
}
#pr-home .nccn-section .nccn-container .card-link{
    margin: 0 24px 4px 0;
}
 .nccn-section .nccn-container .flex-box {
    display: flex;
    justify-content: space-between;
}
.nccn-section .nccn-container .flex-box .pros-footnote {
    margin: 0;
    max-width: 549px;
    width: 100%;
    margin-top: 21px;
}
#pr-efficacy-combination-therapy .pink-bg {
        padding: 20px 0 34px;
}
.pink-bg .max-width p {
        max-width: 1024px;
    margin: 0 auto;
    padding: 0 10px;
    line-height: 32px;
}
.pink-bg .max-width h1 {
    font-size: 30px;
    line-height: 36px;
    margin-top: 0;
    letter-spacing: 0;
}
 .banner-section-2{
        min-width: 672px;
        padding: 0;
    }
    .banner-section-2 .flex-container,.banner-section-2 .flex-container .flex-container {
    flex-direction: row;
}
#pr-main-container #summary-top-section {
    padding: 18px 0 11px;
}
.banner-section-2 .flex-container .percentage.column-1 p{
    margin-left: -13px;
}
     #pr-main-container .scroll-info-section .flex-container {
flex-direction: row;
    padding: 14px 12px;
    gap: 34px;
}
    .banner-section-2 .flex-container, .banner-section-2 .flex-container .flex-container .column-2.content{
            min-height: 74px;
    }
#pr-main-container #summary-bottom-section #flex-container .container.responsivegrid:first-child {
        flex: 0 0 246px;
    }
    .banner-section-2 .flex-container .column .para-1 {
        padding: 0;
    }
    .propel-examined {
        margin: 0 auto;
    flex-direction: row;
        gap: 49px;
        align-items: flex-start;
    }
    #pr-efficacy-combination-therapy #section-2,
    #pr-efficacy-combination-therapy #section-4{
        max-width: 1024px;
        margin: 40px auto 40px;
                padding: 0;
    }
     #pr-efficacy-combination-therapy #section-3{
        max-width: 1024px;
        margin: 0 auto ;
    }

#section-4 .section-heading p {
        margin: 32px 0 23px;
    font-size: 25px;
    line-height: 28px;
}
.propel-examined>p {
        max-width: 100%;
}
    #pr-efficacy-combination-therapy #lt-green-bg{
            background-color: #F8FFF7; 
            padding: 40px 0 20px;
    }
    #pr-efficacy-combination-therapy #section-2-inner{
        background-color: #ffffff;
            padding: 0 20px 0 10px;
    }
    .skew-maroon-head {
            width: 97%;
    padding: 5px 20px 5px 20px;
    margin: 0 auto 0;
    margin-left: 8px;
    }
    .skew-maroon-head h2 {
    max-width: 900px;
    color: #ffffff;
    margin: 10px 0;
    transform: skewX(10deg);
    font-size: 25px;
    line-height: 30px;
    padding-left: 0px;
}
.skew-maroon-head h2  .eff-comb-update {
    font-size: 16px;
    line-height: 20px;
    margin-bottom: 5px;
}
 .propel-content .heading p {
    letter-spacing: 0;
    margin: 16px 0;
}
#pr-efficacy-monotherapy #section-2-inner,
#pr-efficacy-monotherapy #section-3-inner,
#pr-efficacy-monotherapy #section-4-inner,
#pr-efficacy-monotherapy #section-5-inner,
#pr-efficacy-monotherapy #section-6-inner,
#pr-efficacy-monotherapy #section-7-inner,
#pr-efficacy-monotherapy #section-8-inner{
    max-width: 1005px;
    margin: 0 auto;
}
#pr-efficacy-monotherapy #section-1,
#pr-efficacy-monotherapy #section-2,
#pr-efficacy-monotherapy #section-4,
#pr-efficacy-monotherapy #section-6,
#pr-efficacy-monotherapy #section-8{
    background-color: rgba(0, 77, 116, 0.05);
}
#section-4 .skew-maroon-head {
    max-width: 379px;
    padding: 5px 45px 5px 25px;
    margin-top: 0;
}
#section-5 .cta-button ,#pr-efficacy-monotherapy .cta-button{
    justify-content: flex-end;
    max-width: 1005px;
    margin: 0 auto;
}
#pr-efficacy-monotherapy #pr-main-container #summary-bottom-section .image img {
        top: -240px;
        left: -25px;
    }
#pr-efficacy-monotherapy #pr-main-container #summary-section .not-actual-patient {
    color: #000000;
}
#pr-efficacy-monotherapy .pr-hero__container .pink-bg {
       padding: 39px 0 46px; 
}
#pr-efficacy-monotherapy .pink-bg .banner-heading{
        font-size: 30px;
    line-height: 36px;
    margin-top: 0;
}
.graph-head {
    padding-top: 30px;
    overflow: visible;
}
.graph-head .pink-bg.skew-10 {
    margin: 0;
    padding: 0;
}
.graph-head .pink-bg.skew-10 h2 {
        margin: 0;
    padding: 15px 29px;
}
.graph-head .pink-bg.skew-10 h2 .side-heading {
    font-size: 25px;
    line-height: 30px;
}
.graph-head .pink-bg.skew-10 h2 p {
     font-size: 30px;
    line-height: 30px;
}
.monotherapy-heading {
        margin: 31px 0 54px;
    font-size: 25px;
    line-height: 28px;
    padding: 0;
}
    /*#patient-profiles.html#monotherapy*/
#patient-profiles-tab-container-heading .tab-heading{
        max-width: 1005px;
    margin: 0 auto;
}
.patient-profiles-heading {
    margin: 0;
    max-width: 786px;
    font-size: 36px;
    line-height: 43px;
    padding-top: 34px;
}
#patient-profiles-tabs{
    background: #990064;
}
#patient-profiles-tabs .cmp-tabs__tablist{
    max-width: 1005px;
    margin: 0 auto;
            padding: 118px 0 0;
    justify-content: flex-end;
}
#patient-profiles-tabs .cmp-tabs__tablist li {
    padding: 12.5px;
    font-size: 18px;
    line-height: 20px;
}
#patient-profiles-tabs .cmp-tabs__tabpanel{
    background: #fff;
}
.nccn-grey {
       margin: 13px 13.5px 0 6px;
    font-size: 16px;
    line-height: 20px;
    letter-spacing: -0.48px;
    box-sizing: border-box;
    min-width: 280px;
    width: 100%;
    max-width: 280px;
}
.efficacy-secondary-endpoint {
max-width: 922px;
    margin: 80px 0 80px 19px;
}
.efficacy-secondary-endpoint .cohort-a .card-head {
    font-size: 30px;
    line-height: 22px;
}
.efficacy-secondary-endpoint .cohort-a>.skew10 {
    padding: 25px 0 22px 40px;
    max-width: 835px;
    transform: skewX(10deg);
}
.efficacy-secondary-endpoint .cohort-a .card-content {
        font-size: 18px;
    line-height: 23px;
    margin: 12px 0;
}
.efficacy-secondary-endpoint .cohort-a .card-foot{
    font-size: 15px;
    line-height: 22px;
}
.efficacy-secondary-endpoint .cohort-a{
    border-left: 9px solid #990064;
    transform: none;
    max-width: 922px;
}
#pr-efficacy-monotherapy #section-8 {
    padding: 40px 0;
    margin-bottom: 40px;
}
#pr-efficacy-monotherapy #section-8 .monotherapy-heading {
    margin: 0;
}
#section-8-inner .image img {
    margin: 20px 0 0;
    max-width: 100%;
}
.patient-eligibility-note {
        padding-right: 30px;
    margin: 40px 0 40px;
}
#section-8-inner .black-color{
    margin-bottom: 35px;
    max-width: 948px;
    font-size: 20px;
    line-height: 20px;
}
#pr-efficacy-monotherapy  #section-8-inner .list-section .list-item {
    font-family: "roboto", sans-serif;
      font-weight: 400;
    padding-left: 10px;
    font-size: 10px;
    line-height: 14.2857px;
}
#pr-nccn-guidelines .container.responsivegrid #inner-content {
        max-width: 1024px;
        padding: 0 10px;
        padding-right: 20px;
    }
.nccn-table-sec tr:last-child td p {
    padding: 0 6px;
    padding-bottom: 0;
    min-height: 91px;
}
.nccn-table-sec tr:last-child td:nth-child(1) p,
.nccn-table-sec tr:last-child td:nth-child(3) p {
    width: 164px;
}

.nccn-table-sec tr:last-child td:nth-child(2) p,
.nccn-table-sec tr:last-child td:nth-child(4) p {
    width: 183px;
}
.nccn-table-sec tr:last-child td .nccn-grey {
        margin: 0;
}
#pr-nccn-guidelines .nccn-table-sec tr:nth-child(7) td:nth-child(3) p {
        margin-bottom: 0;
    }
#pr-home .combination-container .comb-ref-links .comb-links {
    flex-direction: row;
    padding: 10px 0;
    gap: 27px;
    justify-content: flex-start;
}
#pr-home .combination-container .comb-ref-links .comb-links li a {
        font-size: 13px;
        line-height: 16px;
    }
  
    /*isi*/
#Reference-list .prostate-cancer-indication #pr-home-references .oc-home-footnote{
    margin-bottom: 40px;
}
#pr-home-references  .reference{
    padding-right: 10px;
}
#pr-efficacy-combination-therapy .prostate-cancer-indication p.footnote {
    margin-bottom: 15px;
}
.prostate-cancer-indication .container-center {
    max-width: 1024px;
    margin: 0 auto;
    padding-left: 10px;
    padding-right: 10px;
}
.prostate-cancer-indication .reference.container-center {
    margin-bottom: 45px;
}
#pr-testing-references .reference-container {
    margin: 40px 0;
}
#pr-dosing-references .footnote_end {
    padding-top: 0;
    margin-bottom: 41px;
}
#pr-safety-combination-therapy-references .footnote {
    margin-bottom: 10px;
}
#pr-nccn-guidelines-references   .reference.container-center {
        padding-right: 0px;
    padding-left: 9px;
}
.section-3.flex-box .card .card-content .flex-content .content p:nth-child(2n), .section-3.flex-box .card .card-content .flex-content .content p:nth-child(5) {
    letter-spacing: 0;
    padding-right: 7px;
}
.section-3.flex-box .card .card-content .flex-content .content p:nth-child(5) {
    padding-bottom: 12px;
}
   #pr-efficacy-combination-therapy #summary-top-section #summary-top-section-content {
        padding: 0;
    }
    .banner-section-2 .flex-container {
    gap: 32px;
    }
       #pr-main-container #summary-bottom-section #flex-container .container.responsivegrid:nth-child(2) {
        flex: 0 0 690px;
    }
       #pr-main-container #summary-bottom-section-content {
        max-width: 690px;
        width: 100%;
    }
    
#pr-main-container #summary-bottom-section .image img {
    position: absolute;
    max-width: 292px;
    z-index: 9;
    top: -214px;
    width: 292px;
    left: -22px;
}
    #pr-main-container .scroll-info-section .flex-container .scroll-content{
            min-width: 620px;
    max-width: 620px;
    }
    #pr-main-container #summary-top-section #flex-container{
        gap: 24px;
    }
      #pr-main-container  .banner-section-2 .flex-container {
        gap: 25px;
    }
    #pr-main-container #summary-section .not-actual-patient{
            left: 100px;
    top: 58px;
    }
        #pr-efficacy-combination-therapy #section-2 .skew-maroon-head{
            margin: 0 auto;
            margin-left: 18px;
    width: 94%;
    padding: 5px 20px 5px 25px;
        }
        #pr-efficacy-combination-therapy   #pr-main-container .cta-button a{
            padding: 15px;
        }
     #pr-efficacy-combination-therapy   #pr-main-container .cta-button a:after {
    margin-left: 25px;
}
        #pr-efficacy-combination-therapy #section-3    .skew-maroon-head {
                  width: 94%;
    padding: 5px 45px 5px 25px;  
    margin-top: 0;
            }
              #pr-efficacy-combination-therapy #section-3  .skew-maroon-head h2 {
                        padding: 2px 10px 1px 0px;
                }
                #pr-efficacy-combination-therapy #section-3-inner {
    padding: 0 ;
}
#pr-efficacy-monotherapy .banner-section-2, #pr-efficacy-monotherapy    #summary-top-section #summary-top-section-content  {
    padding: 0;
}
#pr-efficacy-monotherapy #pr-main-container .banner-section-2 .flex-container {
                gap: 36px;
    }
        #pr-efficacy-monotherapy #pr-main-container .banner-section-2 .flex-container  .flex-container  {
        gap: 0;
    }
    #pr-efficacy-monotherapy .banner-section-2 .flex-container .column .column-2.content p:last-child {
        max-width: 214px;
    }
   #pr-efficacy-monotherapy  .banner-section-2 .flex-container .column>p, .banner-section-2 .flex-container .para-2 {
     padding-right: 0; 
}
    #pr-main-container .scroll-info-section .flex-container{
            padding-bottom: 12px;
    }
    #pr-efficacy-monotherapy .propel-examined a.flex-container {
            max-width: 245px;
    padding: 15px 20px;
    align-items: center;
    }
      #pr-efficacy-monotherapy  .efficacy-secondary-endpoint .cohort-a {
            transform: skewX(-10deg);
            margin-left: 0;
        }
            #pr-resource-library .downloadable-pdfs .card {
                padding: 15px 18px;
                margin: 0;
            }
            #pr-resource-library .downloadable-pdfs .pan-col-text {
        padding-right: 0;
    }
    #pr-resource-library  .pan-col-text.margin-right-45{
        padding-right: 50px;
    }
    #pr-main-container .banner-section-2 .flex-container .flex-container{
                gap:0;
                margin-bottom: 2px;
    }
    #pr-efficacy-combination-therapy .propel-examined a.flex-container{
            max-width: 225px;
    padding: 15px 18px;
    }
    .ef-below-gragh-block {
    margin-top: 16px;
}
#pr-efficacy-monotherapy .propel-examined{
    padding-top: 40px;
}
.monotherapy-heading p{
    margin-left: -10px;
}
#pr-efficacy-monotherapy #section-2-inner .image{
    padding: 0;
    margin: 0;
}
.cmp-text .graph-data {
       padding: 20px 0 40px;
}
 #pr-efficacy-monotherapy #section-3-inner .image{
         padding: 0 17px;
    margin: 20px 0 0 0;
 }
 #pr-efficacy-monotherapy #section-4-inner .image{
         margin: 20px 0 0 0;
    padding: 0 51px 0 65px;
 }
 #pr-efficacy-monotherapy #section-5-inner .image,#pr-efficacy-monotherapy #section-6-inner .imag{
     margin: 20px 0 0;
    padding: 0;
 }
 #pr-efficacy-monotherapy #pr-main-container .cta-button a:after {
    margin-left: 19px;
}
  #section-3-inner .monotherapy-heading ,
  #section-4-inner .monotherapy-heading,
  #section-5-inner .monotherapy-heading,
  #section-6-inner .monotherapy-heading {
     margin: 20px 0 0;
 }
 #pr-efficacy-monotherapy #section-3, #pr-efficacy-monotherapy #section-5{
    background-color: #fff;
}
#pr-home #Reference-list .prostate-cancer-indication .footnote,#pr-home .prostate-cancer-indication .reference {
    font-family: "roboto", sans-serif;
      font-weight: 400;
}
#pr-home .prostate-cancer-indication .reference.container-center  {
        padding-right: 10px;
}
#section-5-inner .graph-head .pink-bg.skew-10, #section-6-inner .graph-head .pink-bg.skew-10 {
     margin-right: 0; 
}
#section-4-inner .graph-data .last-para {
    margin-top: 20px;
    padding:0;
}
#pr-efficacy-monotherapy #section-4-inner .graph-data {
    padding: 20px 0 40px;
}
#pr-efficacy-monotherapy #section-4-inner .graph-head .pink-bg.skew-10 {
    margin-right: 0;
}
#pr-efficacy-monotherapy #section-2-inner .list-item .list-bullet {
    margin-left: -15px;
     margin-right: 0; 
}
}

@media only screen and (min-width: 1004px) and (max-width: 1100px) {
    .home-combination .combination-container .section-1 {
        max-width: 524px;
        padding-top: 37px;
    }
}
@media screen and (min-width: 1004px) and (max-width: 1300px) {
  .home-combination .combination-container .section-1{
        max-width: 620px;
        padding-top: 85px;
        
    }
    .home-combination .combination-container, .home-mono .home-mono-container, .home.prostate-home .nccn-section {
        padding: 0 30px;
    }
    .home-combination {
            background-position-x: -140px;
    }
}