#oc-paola-1 .hero {
   padding: 30px 20px 20px 20px; 
}
#oc-paola-1 .esmo-3-heading.green-color{
    font-size: 46px;
    line-height: 46px;
    letter-spacing: -0.3px;
    margin-bottom: 16px;
    color: #B2D234;
    font-style: italic;
    font-family: "roboto", sans-serif;
    font-weight: 900;
    margin-top: 0;
}
#summary-top-section-content .banner-content-solo1{
    margin: 11px 0 4px;
}
#oc-solo-1 #summary-top-section-content .esmo-mbottom_8{
    margin-bottom: 4px;
}
.esmo-italic-gap {
    margin-right: 3px;
}
.mrg-1{
margin-left: 1px;
}
#paola-67-img{
       margin: 20px auto 11px; 
}
#paola1-38-img{
    margin-bottom: 8px;
}
#ovarian-cancer-solo-2 .hero .h1-space-right {
    margin: 0;
    max-width: 1004px;
    font-weight: 700;
}
#ovarian-cancer-solo-2 .hero  h1 span {
    font-style: normal;
    padding-left: 3px;
}
#hrd-testing .container-center,.paola-enrolled.paola-1-sec  .container-center{
    max-width: 1004px;
    margin: 0 auto;
    padding-left: 0px; 
    padding-right: 0px; 
}
#hrd-testing .oc-end-nav-button a {
    padding: 14px 26px;
}
#end-nav-efficacy-paola-1 .esmo-end-nav-sec{
        margin-bottom: 0;
}
#end-nav-efficacy-paola-1 .esmo-end-nav-sec .oc-end-nav-button {
    margin: 0 auto;
}
#end-nav-efficacy-paola-1 .esmo-end-nav-sec .oc-end-nav-button a{
    padding: 14px 27px;
    min-width: 293px;
}
/*#end-nav-efficacy-paola-1 .esmo-end-nav-sec .oc-end-nav-button a:after {*/
/*    right: 26px;*/
/*}*/
#hrd-testing  .oc-end-nav-button {
    width: 215px;
}
#ovarian-cancer-solo-2 .hero  h1  sup{
    font-style: normal;
    font-family: "roboto", sans-serif;
    font-weight: 500;
    font-size: .55em;
    left: 2px;
    top: -11.5px;
}
#ovarian-cancer-solo-2 .hero .h1-space-right i{
    font-size: 30px;
    font-family: "roboto", sans-serif;
  font-weight: 700;
    line-height: 36px;
}
#oc-solo-1 #summary-top-section-content .banner-content-solo1>p:nth-child(3) i {
    padding-right: 3px;
}
#ovarian-cancer-solo-2 .hero .banner-subhead{
    margin-bottom: 10px;
    font-size: 18px;
    font-family: "roboto", sans-serif;
    font-weight: 400;
    line-height: 24px;
    font-style: italic;
}
#oc-paola-1 .hero h2{
margin: 0;
}
#pfs-at-5-years  h2{
    margin: 0;
}
#os-at-7-years .esmo-fs-16 {
    font-size: 16px;
    line-height: 19px;
        margin-bottom: 16px;
}
#oc-solo-1 .esmo-graph-data {
    margin: 16px 0 16px;
}
 .esmo-h2-subhead-eyebrow {
    font-size: 19px;
    line-height: 22px;
    color: #004D74;
    font-family: "roboto", sans-serif;
    font-weight: 700;
    margin-bottom: 5px;
}
.esmo-h2 {
    font-size: 28px;
    line-height: 33px;
    color: #004D74;
}
#oc-paola-1 #summary-top-section {
    background: url(/content/dam/intelligentcontent/brands/lynparzahcp-ic/us/en/images/ovarian-cancer/mobile/paola1-banner-bg.png) no-repeat;
    background-size: cover;
}
/*#oc-solo-1 #study-design .esmo-end-nav-sec .oc-end-nav-button a:after {*/
/*    right: 15px;*/
/*}*/
#pfs-at-5-years  .esmo-graph-update table {
        margin: 20px 0 15px;
    }
 #pfs-at-5-years  .esmo-graph-update table .text-left {
    text-align: left;
}
 #pfs-at-5-years  .chart1{
    padding: 20px 0;
    margin: 0 auto;
}
.esmo-fs-16 {
    font-size: 16px;
    line-height: 19px;
    font-family: "roboto", sans-serif;
    font-weight: 400;
}
#pfs-at-5-years  .footnote-small-q1-npp-update , #os-at-7-years .footnote-small-q1-npp-update ,
#study-design .footnote-small-q1-npp-update  {
        font-size: 13px;
    }
     #pfs-at-5-years .esmo-footnote.ff-roboto-light {
        margin-bottom: 50px;
    }
.esmo-table-text {
    font-family: "roboto", sans-serif;
    font-weight: 400;
        font-size: 13px;
        line-height: 15px;
    }
.updated-bicr-section .content-inner-wrapper {
        padding: 0 0 40px 0;
    }
#oc-paola-1 .hero .esmo-3-subhead{
    margin-bottom: 16px;
    font-size: 19px;
    line-height: 22px;
    font-family: "roboto", sans-serif;
    font-weight: 700;
}
#oc-paola-1 .hero .esmo-h1-foot{
    font-size: 16px;
    line-height: 19.2px;
    font-family: "roboto", sans-serif;
    font-weight: 400;
}
#oc-solo-1 .hero .esmo-h1-eyebrow{
    font-family: "roboto", sans-serif;
    font-weight: 400;
    font-size: 19px;
    line-height: 22.8px;
    font-style: normal;
    color: #FFFFFF;
    padding-left: 2px;
}
#oc-solo-1 .hero {
    padding: 30px 20px;
    position: relative;
    box-shadow: 0px 0px 16px 0px #004D74;
}
#oc-solo-1 .hero .esmo-h1 {
    margin-bottom: -6px;
    margin-top: -3px;
}
#oc-solo-1 #summary-top-section {
    background: #004D741A;
}
#oc-solo-1 #summary-top-section-content p {
    color: #004D74;
    font-size: 16px;
    line-height: 19px;
    font-family: "roboto", sans-serif;
    font-weight: 700;
}
#oc-solo-1 #summary-top-section-content .green-color {
    color: #576B14;
}
#oc-solo-1 #summary-top-section-content .banner-content-solo1>p:nth-child(2),#oc-solo-1 #summary-top-section-content .banner-content-solo1>p:nth-child(3) {
    font-size: 20px;
    line-height: 24px;
}
#oc-solo-1 #summary-top-section-content{
    padding: 20px;
}
.fs-italic {
    font-style: italic;
}
.hrdPositiveChartRhs{
    margin: 20px auto;
    width: 100%;
    max-width: 328px;
}
#oc-solo-1 .years-data {
    margin-top: 16px;
}
.years-data .flex-container {
    flex-direction: row;
    padding: 0;
    align-items: flex-start;
    gap: 16px;
    display: flex;
    max-width: 1014px;
    margin: 0 auto;
}
.years-data .skew-10.bg-blue {
    max-width: fit-content;
    width: 100%;
    box-shadow: 0px 0px 16px 0px #00000040;
}

.bg-blue {
    background-color: #004D74;
}
.skew-10 {
    transform: skewX(-10deg);
}
.skew10 {
    transform: skewX(10deg);
}
.years-data .flex-container:first-child {
    margin-bottom: 18px;
}
#oc-solo-1 #summary-top-section-content .years-data .skew-10.bg-blue>p {
    color: white ;
    font-size: 24px;
    line-height: 30px;
    padding: 10px 16px 11px;
    text-align: center;
    font-family: "roboto", sans-serif;
    font-weight: 700;
}

.scroll-info-section.scroll-info-section--blue ,  #oc-solo-1  #summary-bottom-section {
    background-color: #004D74;
}

.scroll-info-section.scroll-info-section--blue .scroll-content {
    color: #ffffff;
}
#oc-solo-1 #summary-top-section-content .years-data .skew-10.bg-blue>p .green-color {
    color: #B2D234;
}
#Key-eligibility-criteria{
    margin-bottom: 35px;
}
#end-nav-efficacy-paola-1 .esmo-max-width {
    margin: 16px auto 0;
}
 #oc-paola-1 .esmo-max-width,
#pfs .pfs-analysis, #pfs .image, 
#os .pfs-analysis, #os .image,
#pfs-at-5years .pfs-analysis,#pfs-at-5years .image{
        padding: 0 20px;
    }
    #oc-efficacy-paola-1-references .esmo-max-width{
        padding: 0;
    }
#summary-top-section {
    background: url("/content/dam/intelligentcontent/brands/lynparzahcp-ic/us/en/images/oc-home-banner-2%20(1).png") no-repeat;
    background-size: cover;
}
#summary-section   img,#summary-section .not-actual-patient{
display: none;
}
#summary-section  .scroll-icon img{
  display:block;  
          max-width: 28px;
          position: static;
}
#summary-top-section .clinical-results-section{
    padding: 34px 20px 6px 20px;
}
#summary-top-section .primary-endpoint-grid,#summary-top-section .secondary-endpoint-grid{
            display: flex;
    flex-direction: column;
    margin-bottom: 18px;
    
}
#summary-top-section .clinical-results-section .metric-card{
    box-shadow: 0px 4px 16px 0px #0000004D;
    margin: 0 auto 12px;
    padding: 15px 0 16px;
    text-align: center;
    max-width: 140px;
    width: 100%;
    display: flex;
    font-family: "roboto", sans-serif;
    font-weight: 900;
    align-items: center;
    background: #b2d234;
    transform: skewX(-10deg);
}
#summary-top-section .clinical-results-section .skew-inner{
    transform: skewX(10deg);
}
#summary-top-section .clinical-results-section .skew-inner p:first-child{
        font-size: 12.5px;
       font-family: "futura-pt-web", 'roboto';
    line-height: 15px;
    color: #004D74;
    margin-bottom: 10px;
}
#summary-top-section .clinical-results-section .skew-inner p:last-child {
    font-size: 53px;
    line-height: 23px;
    margin: 0;
    letter-spacing: -3px;
    color: #004D74;
}
#summary-top-section .clinical-results-section .skew-inner  p:last-child>span {
    font-size: 23.6px;
    line-height: 28px;
    letter-spacing: 0;
}
#summary-top-section .metric-details .endpoint-title{
    font-size: 20px;
    line-height: 24px;
    color: #fff;
    font-style: italic;
    font-family: "roboto", sans-serif;
    font-weight: 700;
}
#summary-top-section .metric-details .endpoint-label{
    font-size: 16px;
    line-height: 19px;
    color: #fff;
    margin: 5px 0;
    font-family: "roboto", sans-serif;
    font-weight: 400;
}
#summary-top-section .metric-details .endpoint-stat,.endpoint-description{
        font-size: 16px;
    line-height: 19px;
    color: #fff;
    font-family: "roboto", sans-serif;
    font-weight: 400;
}
#summary-top-section .metric-details .stat-bold{
    font-family: "roboto", sans-serif;
    font-weight: 700;
}
#summary-top-section .metric-details .endpoint-description{
    font-style: italic;
}
#summary-top-section .section-link{
    margin: 26px 0 8px;
    font-size: 24px;
    line-height: 28px;
    position: relative;
    color: #fff;
    font-style: italic;
    font-family: "roboto", sans-serif;
    font-weight: 700;
}
#oc-paola-1 .scroll-content .scroll-heading , #oc-paola-1.scroll-content .scroll-description {
    line-height: 20px;
}
#summary-top-section .secondary-endpoint-grid .metric-card {
    margin-bottom: 21px;
}
#summary-top-section .section-disclaimer{
        font-size: 16px;
    line-height: 19px;
    margin: 0 0 8px;
    font-family: "roboto", sans-serif;
    font-weight: 700;
    color: #fff;
}
#summary-top-section .metric-details{
        padding-top: 7px;
}
.scroll-info-section{
        background: #b2d234;
}
.scroll-info-section .flex-container {
       padding: 22px 20px;
    display: flex;
    max-width: 1014px;
    margin: 0 auto;
    gap: 14px;
    align-items: center;
}
.hoc.bg-white .container-center{
    padding: 0 0 30px;
}
#oc-solo-1 #study-design .esmo-end-nav-sec {
    margin: 16px 30px 0 28px;
}
#oc-solo-1 .esmo-end-nav-sec .oc-end-nav-button {
        margin: 0 auto;
    min-width: 282px;
}
#oc-solo-1 .esmo-end-nav-sec .oc-end-nav-button a {
    padding: 14px 27px;
}
#oc-solo-1 .esmo-end-nav-sec {
    margin-bottom: 0;
}
/*#oc-solo-1  .esmo-end-nav-sec .oc-end-nav-button a:after {*/
/*    right: 20px;*/
/* }*/
#oc-efficacy-solo-1-references .esmo-footnote{
    line-height: 15.6px;
}
#orr .esmo-head-flag-sec {
    margin-bottom: 8px;
}
#orr h2{
        margin: 0;
}
.scroll-content{
   font-family: "roboto", sans-serif;
    font-weight: 400;
    color: #004D74;
}
#os-at-7-years .bg-lt-green{
    padding: 16px 8px 10px 20px;
}
#os-at-7-years  .esmo-graph-data .desc p .black-color {
    font-size: 16px;
}
.scroll-content .scroll-heading {
    font-size: 16px;
    line-height: 19px;
    font-style: italic;
    font-family: "roboto", sans-serif;
    font-weight: 700;
}
.scroll-content .scroll-description{
    font-size: 16px;
    line-height: 19px;
    font-style: italic;
}
.esmo-footnote.no-footnote.esmo-fs-16{
    font-size: 16px;
    line-height: 19px;
}
#pfs .paola1-flag-img-sec {
        margin: 8px auto;
        border-bottom: none;
    }
    #pfs .esmo-h2-subhead {
    font-size: 19px;
    line-height: 22.8px;
    margin: 0;
    color: #004D74;
    font-family: "roboto", sans-serif;
    font-weight: 700;
}
#orr .esmo-head-flag-sec p {
        font-family: "roboto", sans-serif;
    font-weight: 700;
}
#pfs .paola1-comp-sec{
    flex-direction: column;
    gap: 24px;
    align-items: center;
    display: flex;
    width: 100%;
    justify-content: space-between;
    margin: 8px 0 24px;
}
.pfs-analysis .esmo-graph-data .bg-lt-green.skew-8 ,
#os .esmo-graph-data .bg-lt-green.skew-8,
#pfs-at-5years .esmo-graph-data .bg-lt-green.skew-8{
        padding: 16px 8px 10px 20px;
}
#pfs-at-5years .esmo-graph-data {
    margin: 16px 0 16px;
}
#os .esmo-graph-data .content.skew8 {
        gap: 9px;
}
.black-color{
    line-height: 20px;
    color: black;
    margin-bottom: 10px;
    font-size: 16px;
    font-family: "roboto", sans-serif;
    font-weight: 400;
}
.esmo-footnote {
    margin: 0;
    padding: 0 0 0 7px;
    font-size: 13px;
    line-height: 15.6px;
}
 .ff-roboto {
   font-family: "roboto", sans-serif;
    font-weight: 400;
}
 .ff-roboto-light {
    font-family: "roboto", sans-serif;
    font-weight: 300;
}
.esmo-jump-link{
  margin-bottom: 10px;  
  margin-top: 8px;
}
#os-at-7-years .esmo-head-flag-sec p {
    margin-bottom: 0;
}
#os-at-7-years .new-pfs-data{
    margin-top: 5px;
}
#os-at-7-years h2{
margin: 0;    
}
.study-design-link{
    flex-direction: column;
    align-items: center;
    max-width: 100%;
    display: flex;
    justify-content: flex-end;
}
.study-design-link a{
    border: 3px solid #004d74;
    border-radius: 100px;
    background: #E4EDC4;
    color: #004D74;
    padding: 10px;
    width: 244px;
    justify-content: center;
    align-items: center;
    display: flex;
    height: 50px;
    text-align: center;
    font-size: 16px;
    line-height: 18px;
    font-family: "roboto", sans-serif;
    font-weight: 700;
}
.esmo-jump-link a{
    color: #004D74;
    font-size: 16px;
    line-height: 19.2px;
    border: 3px solid #004D74;
    border-radius: 25px;
    background: #E3EAC5;
    padding: 12.5px 0;
    display: block;
    min-width: 244px;
    text-align: center;
    font-family: "roboto", sans-serif;
    font-weight: 900;
}
.esmo-jump-link a:after ,.study-design-link a:after{
    content: '';
    background: url(/content/dam/intelligentcontent/brands/lynparzahcp-ic/us/en/images/bottom-icon.svg) no-repeat;
    background-size: 100%;
    width: 17px;
    position: relative;
    display: inline-block;
    height: 17px;
    margin: -3px 0 -3px 10px;
}
 .esmo-h3 {
    font-size: 28px;
    line-height: 33px;
    font-family: "roboto", sans-serif;
    font-weight: 700;
    color: #004D74;
    margin: 0;
}
 .pfs-analysis .margin_8 {
    margin-top: 8px;
    margin-bottom: 8px;
}
.dark-green-color {
    color: #7F9C21;
}
.esmo-h3-eyebrow {
    font-size: 19px;
    line-height: 22px;
    font-family: "roboto", sans-serif;
    font-weight: 700;
    color: #004D74;
    margin: 4px 0;
}
.pfs-analysis {
        margin: 0px auto 40px;
    }
    .esmo-graph-data{
            margin: 12px 0 0;
    display: flex;
    justify-content: center;
    }
   .esmo-graph-data .bg-lt-green.skew-8{
        padding: 6px 20px 8px;
    max-width: 93%;
    background-color: #F7FAEB;
    transform: skewX(-8deg);
    }
   .esmo-graph-data .content.skew8{
            display: flex;
    gap: 9.5px;
    transform: skewX(8deg);
    }
    .esmo-graph-data .percentage{
        font-size: 33px;
    line-height: 39px;
    color: #004D74;
    font-style: italic;
    font-family: "roboto", sans-serif;
    font-weight: 700;
    }
    .esmo-graph-data .desc p{
        font-size: 19px;
    line-height: 22px;
   font-family: "roboto", sans-serif;
    font-weight: 700;
    color: #004D74;
    font-style: italic;
    }
    #oc-paola-1 .esmo-graph-data .desc .number,#oc-paola-1  .esmo-graph-data .desc .number .black-color{
        font-size: 16px;
    }
    .esmo-graph-data  .black-color{
        color: #000;
    }
   #oc-efficacy-paola-1-references .esmo-footnote.no-footnote{
       line-height: 15.6px;
   }
    .esmo-fs-14 {
    font-size: 14px;
    line-height: 17px;
}
.subgroup-data.light-blue-bg {
    background: #EAF2FA;
    padding: 50px 0;
    margin: 50px 0;
}
.subgroup-data .subgrp-text {
    font-family: "roboto", sans-serif;
    font-weight: 400;
    font-size: 18px;
    line-height: 21.6px;
    color: #000000;
    margin-bottom: 15px;
}
.subgroup-data .subgrp-text .fw-bold {
    font-family: "roboto", sans-serif;
    font-weight: 700;
}
.subgroup-data .subgrp-text.fw-bold {
    font-family: "roboto", sans-serif;
    font-weight: 700;
    margin-bottom: 0;
}
/*.esmo-graph-data .desc p:last-child {*/
/*    padding-top: 5px;*/
/*}*/
/*.esmo-graph-data .content .desc {*/
    /* padding-top: 7px; */
/*}*/
.esmo-graph-data .desc .number{
    font-size: 16px;
}
#oc-solo-1 #os-at-7-years{
    margin-bottom: 50px;
}
#oc-solo-1  #study-design .esmo-head-flag-sec p {
    margin-bottom: 0;
}
.esmo-head-flag-sec p {
    color: #004D74;
    transform: skewX(-10deg);
    width: fit-content;
    font-size: 16px;
    line-height: 18px;
    font-family: "roboto", sans-serif;
    font-weight: 900;
    background: #B2D234;
    padding: 4.5px 12px;
    text-transform: uppercase;
    margin-bottom: -2px;
}
.subgroup-data p.subgrp-text.bullet:before {
    content: '•';
    font-size: 24px;
    position: relative;
    left: 0;
}
.subgroup-data.light-blue-bg     .esmo-footnote.no-footnote {
         padding:  0; 
    }
.esmo-head-flag-sec {
    border-bottom: 2px solid #B2D234;
    padding-left: 2px;
}
#oc-solo-1 .study-design-link a:after {
        position: relative;
    right: 10px;
    width: 18px;
    margin: 0;
}
#oc-solo-1 .study-design-link a {
    gap: 10px;
}
#os .esmo-graph-data {
    margin: 40px 0 40px;
}
.pfs-risk-skew-callout {
    background: #004D74;
    transform: skewX(-10deg);
    margin: 0 3px;
}
.pfs-risk-skew-callout p {
    transform: skewX(10deg);
    color: #FFFFFF;
    font-size: 18px;
    line-height: 21px;
    font-family: "roboto", sans-serif;
    font-weight: 900;
    padding: 14px 7px;
    margin-bottom: 0;
}
.green-color {
    color: #B2D234;
}
.esmo-mbottom_8 {
    margin-bottom: 8px;
}
.pfs-risk-list-sec p{
    line-height: 20px;
    font-size: 16px;
    font-family: "roboto", sans-serif;
    font-weight: 400;
}
.pfs-risk-list-sec li {
    font-size: 16px;
    line-height: 19px;
    padding-left: 6px;
    list-style-type: none;
    position: relative;
    margin-bottom: 8px;
    font-family: "roboto", sans-serif;
    font-weight: 400;
}
.os-data.esmo-max-width h2{
    margin: 0;
}
#oc-paola-1 .pfs-risk-list-sec li:before {
    left: -2px;
}
.cmp-text  .pfs-risk-list-sec ul {
    padding-left: 0;
    margin-top: 8px;
    margin-bottom: 10px;
}
.pfs-risk-list-sec li:before, .paola1-sd-endpoints ul li:before {
    content: '•';
    position: absolute;
    left: 0;
    color: #004D74;
}
.pfs-risk-table, .os-risk-table {
    margin: 16px 0;
}
    .esmo-body .esmo-graph-update table {
        margin-top: 16px;
        margin-bottom: 16px;
    }
    .esmo-body .esmo-graph-update table {
    width: 100%;
    }
    .esmo-body .esmo-graph-update table th {
    padding: 9.5px 6px;
    font-weight: normal;
}
#hrd-testing .endpoint-list li b {
       font-family: "roboto", sans-serif;
       font-weight: 700;
    }
.esmo-graph-update table th {
        padding: 10px;
        font-size: 14px;
        line-height: 14px;
        font-weight: 400;
    }
     .esmo-graph-update table td, .esmo-graph-update table th {
    text-align: center;
    border: 1px solid black;
    /*font-size: 16px;*/
    /*line-height: 16px;*/
    width: 33.33%;
}
.blue-color, .blue {
    color: #004D74;
}
.white-color {
    color: #FFFFFF;
}
.bg-lt-green {
    background-color: #EFF6D4;
}
.bg-grey {
    background-color: #7E736D;
}
    .esmo-graph-update table td {
        line-height: 18px ;
        padding: 10px 12px;
        font-size: 14px;
    }
    .ff-roboto-bold {
    font-family: "roboto", sans-serif;
    font-weight: 700;
    }
    .mobile-only{
       display:block; 
    }
    .desktop-only{
        display:none;
    }
    .pfs-clinical-blue-sec {
    background: #EAF2FA;
    padding: 16px 9px;
    margin: 16px 0;
    font-family: "roboto", sans-serif;
    font-weight: 400;
}
.pfs-clinical-blue-sec .head {
    color: #004D74;
    text-transform: uppercase;
}

.pfs-clinical-blue-sec p {
    font-size: 19px;
    line-height: 22px;
    margin-bottom: 8px;
    
}
.clinical-normal-text {
    font-size: 16px;
    line-height: 20px;
    font-family: "roboto", sans-serif;
    font-weight: 700;
    margin-bottom: 8px;
}

.clinical-normal-text:first-child {
    margin-bottom: 16px;
}
.esmo-max-width .esmo-footnote {
    padding: 0 0 0 7px;
}
.pfs-risk-list-sec li[aria-hidden="true"] {
    visibility: hidden;
}
.os-clinical-headline span.green-color {
    color: #7F9C21;
}
.esmo-footnote.no-footnote {
    padding-left: 0;
}
#os-by-clinical-risk {
    margin: 50px 0;
}
    .os-clinical-headline {
    font-size: 18px;
    line-height: 21px;
    font-family: "roboto", sans-serif;
    font-weight: 900;
    color: #004D74;
    margin: 16px 0;
}
.esmo-mbottom_16 {
    margin-bottom: 16px;
}
#study-design .esmo-h3-eyebrow {
    margin: 30px 0;
}
#hrd-testing{
        margin: 50px 0;
}
    .oc-end-nav-button {
        height: 60px;
    margin: 0 auto;
    transform: skewX(-10deg);
    border: 5px solid #B2D234;
    background: #E3EAC5;
    width: 225px;
    }
.oc-end-nav-button a {
    font-size: 19px;
    line-height: 22px;
    font-family: "roboto", sans-serif;
    font-weight: 700;
    color: #004D74;
    padding: 14px 27px;
    display: block;
    text-decoration: none;
}
/*.oc-end-nav-button a:after {*/
/*    content: "\f054";*/
/*    font-family: 'FontAwesome';*/
/*    -webkit-text-stroke: 0.5px #E3EAC5;*/
/*    margin-left: 20px;*/
/*}*/
.pie-head-link-sec {
        flex-direction: column;
        gap: 16px;
    display: flex;
    justify-content: space-between;
}
#hrd-testing li{
    position: relative;
    padding-left: 15px;
    font-family: "roboto", sans-serif;
    font-weight: 400;
    font-size: 16px;
    line-height: 20px;
    padding-right: 2px;
}
#hrd-testing .endpoint-list li::before {
    position: absolute;
    margin: 0;
    left: 0;
    top: -13px;
    content: ".";
    color: #004D74;
    font-size: 40px;
}
.callout-blue {
    background: #EAF2FA;
    padding: 15px 6px;
    padding-right: 30px;
    transform: skewX(-10deg);
    margin-bottom: 10px;
    margin-left: 8px;
    position: relative;
}
.hrdPositiveChartLhs .callout-blue p {
    font-family: "roboto", sans-serif;
    font-weight: 700;
    color: #004D74;
    font-size: 18px;
    line-height: 20px;
    margin: 0;
    position: relative;
    z-index: 999;
    transform: skewX(10deg);
    font-style: italic;
}
.left-cover {
    background: #eaf2fa;
    width: 20px;
    height: 100%;
    position: absolute;
    top: 0;
    left: -10px;
    transform: skewX(10deg);
    z-index: 1;
}
.hrdPositiveChartLhs p {
    font-family: "roboto", sans-serif;
    font-weight: 400;
    color: #000000;
    font-size: 16px;
    line-height: 20px;
    margin: 0 0 10px;
}
.hrd-table .chart-sub-text {
        font-size: 18px;
        line-height: 22px ;
    font-family: "roboto", sans-serif;
    font-weight: 700;
    color: #004D74;
    font-style: normal;
    margin: 0 0 10px;
}
.esmo-graph-img.study-design1-img {
    margin-bottom: 30px;
}
.esmo-graph-update table .bg-lt-grey { 
background: #7E736D80; 
} 

.esmo-graph-update table td.text-left { 
text-align: left; 
} 
.hrdPositiveChart {
        flex-direction: column;
        margin: 20px 0;
        display: flex;
    }
    #hrd-testing .esmo-max-width .esmo-footnote {
    padding: 0 0 0 6px;
}
    .list-view {
    background: #EAF2FA;
}
 .list-view .horline:first-child {
    border-top: 3px solid #004d7470;
        padding: 6px 0 5px;
    text-align: center
}
  .list-view .horline{
    margin: 5px 0px;
    width: 100% ;
    border-bottom: 2px solid #9A9B9F ;
    font-family: "roboto", sans-serif;
    font-weight: 700;
    color: #004D74;
    font-size: 16px;
    padding: 0 0 5px 22px
 }
 .sub-list {
    margin-top: 5px ;
        padding-left: 15px;
        color: #000000;
    font-family: "roboto", sans-serif;
    font-weight: 400;
    }
 .list-view div {
    font-size: 16px;
    line-height: 22.8571px;
}


.sub-list div::before {
    content: "." ;
    color: #004D74;
    font-weight: bold;
    display: inline-block;
    width: 12px;
    margin-left: -14px;
    font-size: 30px;
    position: absolute;
    margin-top: -10px;
}
.normal.esmo-black-color-000 {
    font-family: "roboto", sans-serif;
    font-weight: 400;
    color: #000000;
}
#unprecedented-efficacy #content-inner-wrapper {
        padding: 40px 20px 50px;
    }
    .flex-container.esmo-heading-and-link{
        margin: 18px 0 16px;
    flex-direction: column;
    display: flex;
    }
    #pfs .chart-sub{
        font-size: 19px;
    line-height: 22px ;
    font-family: "roboto", sans-serif;
    font-weight: 700;
    margin-bottom: 12px;
    color: #004D74;
    margin-top: 0;
    }
    #pfs .flex-container.primary-analysis .box-1 p {
        font-size: 19px;
    line-height: 22px;
    margin-bottom: 4px;
    }
    #pfs .esmo-h2 {
        margin: 0 0 16px;
        font-size: 28px;
    line-height: 33px;
    color: #004D74;
    }
    /* #pfs .flex-container.primary-analysis p:last-child {*/
    /*margin-top: 16px;*/
    /* }*/
     #pfs .flex-container.primary-analysis .box-1 .black-color {
    font-size: 16px;
    margin-top: 14px;
    line-height: 19px;
}
      #pfs .flex-container.primary-analysis .visuali {
        margin: 16px 0 0;
    }
    .updated-bicr-section p {
    font-size: 16px;
    line-height: 120%;
    font-family: "roboto", sans-serif;
    font-weight: 400;
}
.oc-p-btm {
    margin-bottom: 6px;
}
   #pfs .foot{
    padding: 13px;
    color: #000000 ;
    font-family: "roboto", sans-serif;
    font-weight: 400;
    margin: 0 0 16px;
    font-size: 16px;
    line-height: 14px;
    border: 1px solid #000000;
    width: 100%;
    max-width: 395px;
    text-align: center;
}
#pfs .updated-bicr-section .esmo-h2 {
        font-size: 19px;
    line-height: 120%;
    margin-top: 16px;
}
#pfs .median.median-f{
        font-size: 16px;
    line-height: 20px;
    font-family: "roboto", sans-serif;
    font-weight: 400;
}
#pfs .median.median-f:last-of-type {
        margin-top: 8px;
    }
     .visuali {
    display: flex;
    flex-direction: column;
    align-items: center;
    width: 100%;
}
.visuali p.head {
    font-size: 19px ;
    line-height: 23px;
    margin-bottom: 0;
    color: #004D74;
    font-family: "roboto", sans-serif;
    font-weight: 700;
}
.visual-sec {
    display: flex;
    flex-direction: row;
    justify-content: center;
    width: 100%;
}
.visual-sec {
        gap: 5px;
    }
    #pfs .flex-container.primary-analysis .visual-box {
    margin: 16px 0 16px 6px;
    height: 51px;
}
#pfs-at-5-years .esmo-head-flag-sec p{
    margin-bottom: 0;
}
#os-at-7-years .esmo-h2 sup{
    margin-left: 1px;
}
#os-at-7-years .esmo-container {
        margin: 10px 0 16px;
}
.visual-box {
    background: #004D74;
    width: 100%;
    max-width: 185px;
    height: 60px;
    display: flex;
    align-items: center;
    justify-content: center;
    margin: 12px 6px;
    transform: skewX(-10deg);
    padding: 10px;
    text-align: center;
}
.visual-box span {
    font-size: 16px;
    line-height: 22px;
    font-family: "roboto", sans-serif;
    font-weight: 700;
    color: #fff;
    transform: skewX(10deg);
}
.visual-box:last-child {
    background: #7E736D;
}
#study-design .esmo-end-nav-sec .oc-end-nav-button a {
    padding: 4px 50px 2px 25px;
    position: relative;
}
#study-design .image-section {
        margin: 16px 0;
}
#orr .top-img {
        margin-top: 40px;
        text-align: center;
        width: 100%;
    }
    .orr-top-content .center-text span {
    color: #7E736D;
}
.orr-top-content .center-text span .txt-blue{
        color: #004d74;

}
#orr .orr-div.one{
    padding-top: 7%;
}
#orr  .center-text  {
    font-size: 19px;
    line-height: 23px;
    margin-top: 25px;
    text-align: center;
    color: #004d74;
    font-family: "myriad-pro", sans-serif;
    font-weight: 700;
}
.orr-lynp-container .orr-lynp {
        padding: 0 0 43px;
        display: flex;
        flex-direction: column;
        align-items: center;
    }
#orr .container-center.content-inner-wrapper {
        padding: 50px 0;
    }
  .orr-lynp-container .orr-lynp .orr-mid-grid    {
    margin: 15px 0;
    max-width: 100%;
    padding: 10px 30px 20px;
    height: auto;
    border: 1px solid #B2D234;
    background-color: #F7FAEB;
}
.orr-lynp-container .orr-lynp .orr-mid-grid .orr-callout {
    margin-top: 15px;
    background-color: transparent;
    font-family: "roboto", sans-serif;
    font-weight: 700;
    padding: 4px 0;
    transform: skewX(-10deg);
    max-width: 90%;
    width: 100%;
    display: inline-block;
}
#orr .orr-lynp-container .orr-callout p{
    font-size: 26px;
    font-family: "myriad-pro", sans-serif;
    font-weight: 900;
    color: #004d74;
    transform: skewX(10deg);
    line-height: 24px;
    font-style: italic;
    margin-top: 0;
}
#orr .orr-lynp-container p{
    font-family: "myriad-pro", sans-serif;
        font-weight: 400;
    border: none;
    font-size: 20px;
    max-width: 100%;
    padding: 0 5px;
    margin-top: 0;
    color: #000000;
    line-height: 22px;
}
.orr-lynp-container .orr-block p b {
            font-family: "myriad-pro", sans-serif;
    font-weight: 900;
        color: #004d74;
    font-style: italic;
    }
   #orr .hoc p {
    font-size: 16px;
    line-height: 20px;
    color: #000;
    font-family: "roboto", sans-serif;
    font-weight: 400;
    padding: 0;
    text-align: left;
}
.hrd-table table th:last-child span {
    display: block;
    font-family: "roboto", sans-serif;
    font-weight: 300;
    font-size: 16px;
    line-height: 18px;
}
#hrd-testing .hrd-table .esmo-update-table td {
    background-color: rgba(19, 19, 19, 0.1);
    padding: 7px 0;
}

#hrd-testing  .container-center .fs-normal {
    padding: 0;
}
.hrdPositiveChartLhs .callout-blue p {
    font-style: normal;
}
.esmo-graph-data .desc p  .black-color {
    color: #000;
    font-size: 19px;
    line-height: 22px;
    font-family: "roboto", sans-serif;
    font-weight: 700;
}
.esmo-max-width .esmo-footnote.ff-roboto {
    font-family: "roboto", sans-serif;
    font-weight: 400;
}
#oc-paola-1 .select-from-text .sticky-desc {
    font-size: 12px;
    line-height: 20px;
}
#oc-paola-1 #pfs, #oc-paola-1 #os, #oc-paola-1 #pfs-at-5years, #oc-paola-1 #pfs-by-clinical-risk,
#oc-paola-1 #os-by-clinical-risk, #oc-paola-1 #study-design,#oc-paola-1 #hrd-testing ,
#oc-solo-1 #pfs, #oc-solo-1 #pfs-at-5-years, #oc-solo-1 #os-at-7-years, #oc-solo-1 #orr, #oc-solo-1 #study-design {
    scroll-margin-top: 175px;
}
#study-design-solo2-inner, #bicr2-inner,#paola-2-sec-inner{
    scroll-margin-top: 190px;
}
@media only screen and (min-width: 992px) {
    #oc-paola-1 #pfs,#oc-paola-1 #pfs-at-5years, #oc-paola-1 #pfs-by-clinical-risk,
#oc-paola-1 #os-by-clinical-risk,#oc-paola-1 #hrd-testing ,
#oc-solo-1 #pfs-at-5-years, #oc-solo-1 #os-at-7-years,  #oc-solo-1 #study-design{
    scroll-margin-top: 190px;
}
#oc-solo-1 #orr{
 scroll-margin-top: 140px;   
}
 #oc-paola-1 #os{
   scroll-margin-top: 195px;  
 }
 #oc-solo-1 #pfs{
   scroll-margin-top: 180px;  
 }
  #oc-paola-1 #study-design {
    scroll-margin-top: 190px;
}
    .desktop-only{
        display:block;
    }
    .mobile-only{
       display:none;
    }
    .esmo-graph-update table th ,.esmo-graph-update table td {
    font-size: 16px;
    line-height: 16px;
    padding: 12px;
}
.esmo-table-text{
    padding-right: 10px;
}
.hrd-table table th:first-child ,.hrd-table table th:last-child {
    line-height: 24px;
}
.clinical-normal-text {
    font-size: 16px;
    line-height: 20px;
}
.hrd-table .chart-sub-text {
    font-size: 20px;
    line-height: 28px;
}
    #ovarian-cancer-solo-2 .hero {
      padding: 50px 0;  
    }
    #study-design .esmo-end-nav-sec .oc-end-nav-button a {
    padding: 14px 10px 12px 20px;
}
/*#oc-solo-1 #study-design .esmo-end-nav-sec .oc-end-nav-button a:after {*/
/*    right: 18px;*/
/*}*/
.orr-lynp-container .orr-lynp {

    flex-direction: row;
}
    .list-view .horline:first-child {
    padding-left: 22px;
    text-align: left;
}
     .sub-list div::before {
        margin-left: -11px;
    }
    .hrdPositiveChart {
        flex-direction: row;
        margin: 40px 0 24px;
    }
    .paola1-flag-img-sec img {
    margin-bottom: -10px;
}
#oc-paola-1 .esmo-max-width,
#pfs .pfs-analysis, #pfs .image,
#os .pfs-analysis, #os .image,
#pfs-at-5years .pfs-analysis, #pfs-at-5years .image {
    padding: 0;
}
    #pfs .paola1-flag-img-sec {
    margin: 16px auto 13px;
    border-bottom: 2px solid #004D74;
}
    .pfs-clinical-comp-data-sec1 ,.os-clinical-comp-data-sec {
    display: flex;
    gap: 16px;
}
.esmo-graph-img img{
    width: 100%;
}
    .col-sm-4 {
        width: 33.33333333%;
    }
    .orr-lynp-container .orr-lynp>.col-xs-12.col-sm-4:last-child {
        position: relative;
    right: 5px;
    bottom: 7px;
    }
    #oc-paola-1 .hero {
       padding: 32px 0; 
    }
    #oc-paola-1 .esmo-3-heading.green-color {
        font-size: 54px;
    line-height: 64.8px;
    text-shadow: none;
    margin-bottom: 8px;
    letter-spacing: 0;
    }
    #oc-paola-1 .hero .esmo-3-subhead{
        font-size: 23px;
    line-height: 27.6px;
    margin-bottom: 10px;
    }
    #oc-paola-1 #summary-top-section{
    background: url("/content/dam/intelligentcontent/brands/lynparzahcp-ic/us/en/images/desktop/oc-home-banner-2.jpg") no-repeat;
    background-size: cover;
}
#summary-section   img,#summary-section .not-actual-patient{
display: block;
}
#summary-section #summary-top-section img{
      visibility: hidden;
    max-height: 300px;  
}
    #summary-top-section #flex-container{
        gap: 16px;
    }
   #summary-bottom-section #flex-container{
       gap: 20px;
   }
    #oc-solo-1 .years-data {
        margin-left: 5px;
    }
    #oc-solo-1 #summary-top-section-content .esmo-mbottom_8{
        margin-bottom: 4px;
    }
#summary-top-section #flex-container ,#summary-bottom-section #flex-container{
    display: flex;
    max-width: 1014px;
    margin: 0 auto;
}
#summary-top-section #summary-top-section-img{
width: 336px;
    
}
#summary-top-section #summary-top-section-content{
    max-width: 658px;
    width: 100%;
        padding: 11px 0 0 0;
}
#summary-top-section .primary-endpoint-grid{
    margin-bottom: 12px;
    margin-top: 22px;

}
#summary-top-section .primary-endpoint-grid, #summary-top-section .secondary-endpoint-grid {
    flex-direction: row;
    
}
#summary-top-section .clinical-results-section {
     padding: 0px; 
}
#summary-bottom-section-img .image{
    position: relative;
    max-width: 336px;
    width: 100%;
}
#summary-bottom-section img{
    position: absolute;
    max-width: 326px;
    z-index: 9;
       top: -350px;
}

#summary-bottom-section-content{
    max-width: 658px;
    width: 100%;
}
    #summary-bottom-section{
        background: #b2d234;
    }
    #summary-top-section .clinical-results-section .metric-card {
    margin-right: 22px;
    padding-top: 20px;
    padding-bottom: 20px;
}
/*#summary-top-section .clinical-results-section .skew-inner p:first-child {*/
/*    font-size: 9.5px;*/
/*}*/
.metric-details{
    padding: 7px 0 6px 7px;
}
#oc-paola-1 #summary-top-section #summary-top-section-content {
        padding: 0; 
    }
.primary-endpoint-grid .metric-details{
        padding-left: 0;
}
#summary-top-section .secondary-endpoint-grid {
    margin-bottom: 0;
}
#summary-top-section .section-link {
    margin-top: 4px;
    margin-left: -10px;
}
#summary-top-section .section-disclaimer {
    margin-left: -10px;
}
#oc-solo-1 .select-from-text {
        padding: 19px 0 17px;
    }
  #oc-solo-1  .study-design-link a {
        padding-left: 0px;
    }
    .flex-container.esmo-heading-and-link {
            margin: 30px 0 30px;
    }
    .esmo-footnote.esmo-fs-14 {
        padding: 0;
    }
     #oc-paola-1 #pfs .pfs-analysis p.esmo-footnote{
    padding: 0;
    max-width: 997px;
    margin: 0 auto;
    }
    #oc-paola-1 #pfs .image{
            max-width: max-content;
    }
/*#summary-bottom-section-img{*/
/*    width: 336px;*/
/*}*/
.scroll-info-section .flex-container{
    padding: 12px 0;
    gap: 37px;
}
#summary-section .scroll-icon img {
    max-width: 32px;
}
#summary-section .not-actual-patient{
    left: 131px;
    bottom: 25px;
    text-shadow: 0px 0px 9px #ffffff, 1px 0px 10px #ffffff;
    font-family: "roboto", sans-serif;
    font-weight: 400;
    line-height: 19px;
    top: 38px;
    position: absolute;
    color: black;
    font-size: 16px;
    z-index: 9;
}
#summary-section .scroll-icon img{
    height: 48px;
    width: 48px;
}
#summary-bottom-section #flex-container .container.responsivegrid:first-child {
    flex: 0 0 336px;
}

#summary-bottom-section #flex-container .container.responsivegrid:nth-child(2) {
    flex: 0 0 658px;
}
#pfs .paola1-comp-sec{
    flex-direction: row;
    gap: 40px;
}
#pfs .pfs-analysis, #pfs .image,
#os .pfs-analysis, #os .image,
#pfs-at-5years .pfs-analysis, #pfs-at-5years .image{
        margin: 0 auto;
    max-width: 1004px;
}
.pfs-clinical-low-risk {
    flex: 0 0 505px;
}
.pfs-clinical-high-risk{
    flex: 0 0 482px;
}
.pfs-clinical-blue-sec {
        margin-top: 108px;
    }
       .middle-para {
        position: absolute;
        max-width: 1004px;
    }
    .esmo-footnote.no-footnote {
    padding: 16px 0;
}
/*.clinical-normal-text {*/
/*    margin-bottom: 16px;*/
/*}*/
.hrdPositiveChartRhs {
    width: 32%;
    order: 2;
    margin: 0 22px;
}
.hrd-table {
    width: 33%;
    order: 3;
}
.hrdPositiveChartLhs {
    width: 32%;
    margin: 0;
    order: 1;
}
.pie-head-link-sec {
    flex-direction: row;
}
.flex-container.esmo-heading-and-link{
        flex-direction: row;
    align-items: flex-start;
}
#pfs .flex-container.primary-analysis {
    margin-bottom: 30px;
        display: flex;
}
#pfs .flex-container.primary-analysis .visuali {
    max-width: 408px;
    margin-left: 63px;
    margin-top: 0;
}
#pfs .flex-container.primary-analysis .box-1 {
    max-width: 494px;
    width: 100%;
}
#pfs-at-5-years  .footnote-small-q1-npp-update , #os-at-7-years .footnote-small-q1-npp-update,
#study-design .footnote-small-q1-npp-update{
    font-size: 14px;
}
#os-at-7-years .esmo-footnote.no-footnote {
        padding: 0; 
    }
#unprecedented-efficacy{
    max-width: 1024px;
    margin: 0 auto;

}
.esmo-footnote.no-footnote.esmo-fs-16 {
    margin: 0;
}
#pfs-at-5-years .chart1 {
    padding-top: 95px;
    padding-bottom: 10px;
    margin: 0;
}
#unprecedented-efficacy #content-inner-wrapper {
    padding: 40px 0 0;
}
.esmo-container .esmo-graph-update {
        max-width: 334px;
        width: 100%;
        position: absolute;
        right: 0;
        font-family: "myriad-pro", sans-serif;
        top: -53px;
    }
         .esmo-container {
        position: relative;
          margin: 50px 0 22px;
         }
         #pfs-at-5-years .esmo-graph-update table {
    margin: 20px 0 8px;
}
#pfs-at-5-years .esmo-graph-update table .text-left {
    padding: 12px;
}
    #oc-paola-1 #study-design .esmo-head-flag-sec.esmo-mbottom_16{
    margin-bottom: 30px;
}
#oc-paola-1 #study-design  .ast-foot-symbol {
    margin-left: -7px;
}
#oc-paola-1 #study-design .esmo-footnote.no-footnote {
         padding: 0;
    }
#oc-paola-1 #study-design  .ss-mleft {
    margin-left: 3px;
}
#hrd-testing .container-center ,.paola-enrolled .container-center{
   padding: 0; 
}
#hrd-testing .esmo-h3-eyebrow {
    margin-top: 0;
}

#hrd-testing .endpoint-list li b{
    font-family: "roboto", sans-serif;
    font-weight: 700;
}
   .oc-end-nav-button {
       margin: 0;
    max-width: 216px;
    position: relative;
    margin-bottom: -60px;
    margin-top: 20px;
   }
   .hrdPositiveChartLhs .callout-blue p {
    font-size: 16px;
    padding-right: 0;
   }
   #hrd-testing .esmo-max-width .esmo-footnote {
    padding: 0 0 0 5px;
}
.sub-list {
    padding-left: 10px;
}
.hrd-table table th:last-child {
    padding: 10px 12px;
}
.hrdPositiveChartLhs p {
    padding-right: 42px;
}
#oc-paola-1 .esmo-end-nav-sec .oc-end-nav-button {
    min-width: 303px;
        margin: 0 0 0 auto;
}
#oc-paola-1 .esmo-end-nav-sec .oc-end-nav-button a {
    padding: 14px 27px;
}
/*#oc-paola-1 .esmo-end-nav-sec .oc-end-nav-button a:after {*/
/*        content: '';*/
/*    border: 4px solid #004d74;*/
/*    border-bottom: none;*/
/*    border-left: none;*/
/*    width: 14px;*/
/*    height: 14px;*/
/*    position: relative;*/
/*    right: -28px;*/
/*    top: 0;*/
/*    margin-left: -20px;*/
/*    display: inline-block;*/
/*    transform: rotate(40deg);*/
/*}*/
#oc-solo-1     #summary-bottom-section-img .image {
   width: 409px; 
   max-width: 100%;
}
   #oc-solo-1 #summary-bottom-section img {
        top: -252px;
        min-width: max-content;
    }
    #oc-solo-1 .hero {
           box-shadow: 0px 0px 16px 0px #004D74;
    padding: 32px 0; 
    }
    #oc-solo-1 .hero .esmo-h1 {
    margin-bottom: 0;
    margin-top: 0;
    padding: 8.5px 0;
}
#pfs-at-5-years .esmo-head-flag-sec p {
        margin-bottom: 0;
}
.visual-sec {
    gap: 0px;
}
#pfs .flex-container.primary-analysis .visual-box {
        max-width: 190px;
}
.visual-box span {
    font-size: 19px;
}
#pfs .median.median-f:last-of-type {
    margin-top: 16px;
}
#unprecedented-efficacy #pfs,
#unprecedented-efficacy #pfs-at-5-years,
#unprecedented-efficacy #os-at-7-years,
#orr .hoc p {
    padding: 0 10px;
}
.orr-lynp-container .orr-lynp {
        padding: 0 10px 43px;
    }
#unprecedented-efficacy #study-design{
        margin-top: 50px;
}
#unprecedented-efficacy #study-design .esmo-head-flag-sec{
    margin-bottom: 40px;
}
#unprecedented-efficacy #study-design .image-section{
        margin: 32px 0;
}
#os-at-7-years .new-pfs-data h2{
    margin: 5px 0 0;
}

   #os-at-7-years .esmo-container {
            margin: 10px 0 0;
    }
    .esmo-graph-data .desc p:last-child {
    padding-top: 5px;
        font-size: 16px;
}
        .clinical-normal-text.esmo-desktop-mbottom_16 {
        margin-bottom: 16px;
    }
.updated-bicr-section .content-inner-wrapper {
    padding: 0 0 50px 0;
}
#oc-solo-1 #study-design .esmo-end-nav-sec.esmo-max-width.solo1-testing-link {
        margin: auto 20px auto auto;
        max-width: 480px;
        width: 100%;
    }
    #oc-solo-1 .esmo-end-nav-sec.esmo-max-width .oc-end-nav-button {
        margin: 0 0 0 auto;
    }
    #orr .container-center.content-inner-wrapper{
            padding: 50px 0 10px;
    }
    #orr .esmo-h3 {
    padding-top: 5px;
}
#oc-solo-1   #orr .esmo-end-nav-sec {
    width: 301px;
        margin: 0 0 0 auto;
        padding-right: 10px;
        padding-top: 10px;
}
   #os .esmo-graph-data .desc p:last-child {
        padding-top: 5px;
         font-size: 19px; 
    }
    #survival-data-section .btn-outline {
        font-style: normal;
    }
    
#orr .center-text{
    font-family: "roboto", sans-serif;
    font-weight: 500;
    padding-right: 30px;
    padding-bottom: 10px;
}
.orr-lynp-container .orr-lynp .orr-mid-grid{
    height: auto;
    min-height: 318px;
    margin: 0px 24px;
    max-width: 304px;
    width: 100%;
    font-family: "myriad-pro", sans-serif;
    padding: 0;
    position: relative;
    right: 27px;
    top: 5px;
}
#orr .orr-lynp-container .orr-callout p {
        padding: 0;
}
#orr .orr-lynp-container p {
      padding: 0 28px; 
      line-height: 24px;
}
#orr .orr-div.one {
    padding-top: 0; 
}
.orr-mid-grid .orr-block:last-child .orr-callout {
    margin-top: 31px;
}
   #oc-solo-1 #summary-top-section #summary-top-section-content {
        max-width: 658px;
        width: 100%;
        padding: 0 0 32px 0;
    }
#pfs .flex-container.primary-analysis .visual-box{
    margin: 16px 6px;
}
#oc-solo-1 #pfs-at-5-years .esmo-graph-update table th {
    padding: 10px 0;
}
#oc-solo-1 .study-design-link a {
     gap: 0; 
}
#oc-solo-1 .study-design-link a:after {
    position: static;
    width: 18px;
    margin: -3px 0 -3px 10px;
}
   #oc-paola-1 #summary-top-section #flex-container {
        gap: 20px;
    }
    #oc-paola-1 #summary-section .not-actual-patient {
        font-weight: 700;
    left: 10px;
    top: 42px;
    text-shadow: 0px 0px 8px #FFFFFF;
    }
    #oc-paola-1 #summary-top-section .clinical-results-section .metric-card {
            margin-right: 16px;
    margin-bottom: 0;
    }
   #oc-paola-1 #summary-top-section .primary-endpoint-grid{
        margin-bottom: 23px;
    margin-top: 22px;
    }
     #oc-paola-1 #summary-top-section .metric-details {
        padding: 7px 0 7px 6px;
    }
     #oc-paola-1 .secondary-endpoint-grid .metric-details {
            padding: 7px 0 7px 6px;
    margin-left: 6px;
    }
        #oc-paola-1 #summary-top-section .section-link {
           margin: 16px 0 8px;
    margin-left: -10px; 
        }
        #end-nav-efficacy-paola-1 .esmo-max-width {
    margin: 50px auto 0;
}
#oc-dosing .dose-card.card-2 .dose-text {
    width: 56%;
}
#oc-dosing .dose-card.card-2 .dose-image.img-2 img {
            position: relative;
        width: 54px;
        max-width: 54px;
        top: 10px;
}
.pfs-analysis .esmo-footnote.esmo-fs-14{
        padding-left: 7px;
}
.pfs-analysis .esmo-footnote.esmo-fs-14 .single-foot-symbol {
    margin-left: -5px;
}
#video-thumbnail-container-1 .image .cmp-image__image {
    min-height: 255px;
}
#oc-moa .parbase .moa-bottom-content {
    padding: 0;
}
.parbase .footnote-content .new.thick-txt{
        padding: 20px 10px 10px;
}
br.sp-content {
        display: none;
    }
   #oc-safety-tolerability-solo-1-page .safety-year-section.is-desktop .safety-main-title{
               margin: 20px 0 15px -20px;
   }
       .cmp-text #adverse-reactions .safety-footnotes {
        padding-bottom: 8px;
    }
    #adverse-reactions table {
    min-width: 1004px;
}
#oc-dosing .dose-title {
        margin-right: 0;
    }
        .order-button a:hover {
    text-decoration: none;
}
}
@media (max-width: 991px) {
    .sticky-nav {
        position: static !important;
        width: 100% !important;
    }
   #oc-brca-testing #brca-detection-panel-inner {
    padding: 20px 20px 30px 10px;
}
    .os-risk-img-sec {
        margin-bottom: 16px;
    }
    .pfs-risk-list-sec li[aria-hidden="true"] { 
visibility: hidden; 
display: none; 
} 
}